DK0925290T3 - Fremgangsmåde til selektiv alkylering af epoxy-alkoholer - Google Patents
Fremgangsmåde til selektiv alkylering af epoxy-alkoholerInfo
- Publication number
- DK0925290T3 DK0925290T3 DK97930006T DK97930006T DK0925290T3 DK 0925290 T3 DK0925290 T3 DK 0925290T3 DK 97930006 T DK97930006 T DK 97930006T DK 97930006 T DK97930006 T DK 97930006T DK 0925290 T3 DK0925290 T3 DK 0925290T3
- Authority
- DK
- Denmark
- Prior art keywords
- selective alkylation
- epoxy alcohols
- alcohols
- epoxy
- alkylation
- Prior art date
Links
- 230000029936 alkylation Effects 0.000 title abstract 2
- 238000005804 alkylation reaction Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000004593 Epoxy Substances 0.000 title 1
- 150000001298 alcohols Chemical class 0.000 title 1
- NWIUTZDMDHAVTP-UHFFFAOYSA-N betaxolol Chemical compound C1=CC(OCC(O)CNC(C)C)=CC=C1CCOCC1CC1 NWIUTZDMDHAVTP-UHFFFAOYSA-N 0.000 abstract 1
- 229960004324 betaxolol Drugs 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/667,038 US5942633A (en) | 1996-06-19 | 1996-06-19 | Process for the selective alkylation of betaxolol intermediates |
| PCT/US1997/010337 WO1997048690A1 (fr) | 1996-06-19 | 1997-06-18 | Procede pour l'alkylation selective d'epoxy-alcools |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0925290T3 true DK0925290T3 (da) | 2004-03-29 |
Family
ID=24676556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97930006T DK0925290T3 (da) | 1996-06-19 | 1997-06-18 | Fremgangsmåde til selektiv alkylering af epoxy-alkoholer |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5942633A (fr) |
| EP (1) | EP0925290B1 (fr) |
| JP (1) | JP2000512999A (fr) |
| AT (1) | ATE254610T1 (fr) |
| DE (1) | DE69726293T2 (fr) |
| DK (1) | DK0925290T3 (fr) |
| ES (1) | ES2212113T3 (fr) |
| PT (1) | PT925290E (fr) |
| WO (1) | WO1997048690A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7019172B2 (en) * | 2004-06-30 | 2006-03-28 | Council Of Scientific And Industrial Research | Process for preparation of S-(-)-betaxolol and salts thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3541130A (en) * | 1967-02-06 | 1970-11-17 | Boehringer Sohn Ingelheim | 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes |
| GB1285038A (en) * | 1969-02-21 | 1972-08-09 | Ici Ltd | Alkanolamine derivatives |
| US4018778A (en) * | 1972-05-24 | 1977-04-19 | Cassella Farbwerke Mainkur Aktiengesellschaft | Derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production |
| FR2330383A1 (fr) * | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
| CA1265523A (fr) * | 1984-08-21 | 1990-02-06 | Stephen Vigmond | Preparation d'ethers phenoliques a l'aide d'intermediaires cycliques |
| ES8609190A1 (es) * | 1985-02-07 | 1986-07-16 | Pharma Investi S A | Un procedimiento para preparar eteres fenolicos |
| SE8801518D0 (sv) * | 1988-04-22 | 1988-04-22 | Astra Pharma Prod | A novel process |
| US5208352A (en) * | 1992-04-02 | 1993-05-04 | Sandoz Ltd. | Process for preparing the R- and S-isomers of 2-hydroxy-methyl-2-octadecyloxymethyl-tetrahydrofuran and their use in preparing stereoisomers of pharmacologically active compounds |
-
1996
- 1996-06-19 US US08/667,038 patent/US5942633A/en not_active Expired - Lifetime
-
1997
- 1997-06-18 WO PCT/US1997/010337 patent/WO1997048690A1/fr not_active Ceased
- 1997-06-18 PT PT97930006T patent/PT925290E/pt unknown
- 1997-06-18 JP JP10503173A patent/JP2000512999A/ja not_active Ceased
- 1997-06-18 DK DK97930006T patent/DK0925290T3/da active
- 1997-06-18 EP EP97930006A patent/EP0925290B1/fr not_active Expired - Lifetime
- 1997-06-18 DE DE69726293T patent/DE69726293T2/de not_active Expired - Lifetime
- 1997-06-18 AT AT97930006T patent/ATE254610T1/de active
- 1997-06-18 ES ES97930006T patent/ES2212113T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000512999A (ja) | 2000-10-03 |
| DE69726293T2 (de) | 2004-09-23 |
| US5942633A (en) | 1999-08-24 |
| ATE254610T1 (de) | 2003-12-15 |
| PT925290E (pt) | 2004-04-30 |
| EP0925290A1 (fr) | 1999-06-30 |
| EP0925290B1 (fr) | 2003-11-19 |
| ES2212113T3 (es) | 2004-07-16 |
| DE69726293D1 (de) | 2003-12-24 |
| WO1997048690A1 (fr) | 1997-12-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL135590A (en) | Process for the reduction of oxiranyl epothilones to olefinic epothilones | |
| IS5447A (is) | Ferli til að smíða 1,3-díól | |
| DK0960109T3 (da) | Fremgangsmåde til fremstilling af tolterodin | |
| DK0937055T3 (da) | Fremgangsmåde til fremstilling af d,I-alfa-tocopherol | |
| ITTO960495A0 (it) | Procedimento per accrescere il flusso per elettrotrasporto di polipep-tidi. | |
| ES2109103T3 (es) | Procedimiento para la preparacion de trialquilsilil-7 bacatina iii. | |
| EA199900741A1 (ru) | Способ получения эпросартана | |
| DK1206452T3 (da) | Fremgangsmåde til fremstilling af benzoperhydro-isoindolforbindelser | |
| EA199900740A1 (ru) | Способ получения эпросартана (варианты) | |
| DK0931055T3 (da) | Selektiv alkylering af en alkohol-substitueret phenolforbindelse | |
| ES2177877T3 (es) | Procedimiento para la fabricacion de 1,4-bis(aminometil)ciclohexano. | |
| DK0925290T3 (da) | Fremgangsmåde til selektiv alkylering af epoxy-alkoholer | |
| MX9706744A (es) | Proceso novedosos para preparar derivados de 2,3-dihidro-benzofuranol. | |
| DK1308454T3 (da) | Fremgangsmåde til fremstilling af platinforbindelse | |
| DK0815092T3 (da) | Fremgangsmåde til fremstilling af 1,2-benzisothiazolin-3-oner | |
| DK0915858T3 (da) | Mellemprodukter til fremstilling af 2-imidazolin-5-oner | |
| DK27894A (da) | Fremgangsmåde til genvinding af alkyleringskatalysator | |
| IT1286475B1 (it) | Dispositivo per distribuire trucioli,particolarmente trucioli lunghi, nel corso della fabbricazione di piastre truciolari a orientamento | |
| DK1023292T3 (da) | Fremgangsmåde til syntese af chlorpurinintermediater | |
| EA200001153A1 (ru) | Очистка карбоксальдегида | |
| DK0975601T3 (da) | Fremgangsmåde til fremstilling af butylthio-isoquinolin og mellemprodukter derfor | |
| MX9305844A (es) | Procedimiento para preparar 1-alquilaril-2-alquil-5-formilimidazoles. | |
| DK0934256T3 (da) | Fremgangsmåde til fremstilling af cyanocinnamamider | |
| DK16496A (da) | Fremgangsmåde til trinvis alkylering af carbonhydridstrømme | |
| IS1853B (is) | Ný aðferð til að búa til 3-N,N-dísýklóbútýlamínó-8-flúor-3,4-díhýdró-2H-1-bensópýran-5-karboxamíð |