[go: up one dir, main page]

DK0946538T3 - Indan- eller dihydroindole derivater - Google Patents

Indan- eller dihydroindole derivater

Info

Publication number
DK0946538T3
DK0946538T3 DK97949999T DK97949999T DK0946538T3 DK 0946538 T3 DK0946538 T3 DK 0946538T3 DK 97949999 T DK97949999 T DK 97949999T DK 97949999 T DK97949999 T DK 97949999T DK 0946538 T3 DK0946538 T3 DK 0946538T3
Authority
DK
Denmark
Prior art keywords
compounds
indan
optionally substituted
dihydroindole
dopamine
Prior art date
Application number
DK97949999T
Other languages
English (en)
Inventor
Ivan Mikkelsen
Henrik Pedersen
Jens Kristian Perregaard
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of DK0946538T3 publication Critical patent/DK0946538T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK97949999T 1996-12-20 1997-12-19 Indan- eller dihydroindole derivater DK0946538T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK146996 1996-12-20
PCT/DK1997/000588 WO1998028290A1 (en) 1996-12-20 1997-12-19 Indane or dihydroindole derivatives

Publications (1)

Publication Number Publication Date
DK0946538T3 true DK0946538T3 (da) 2003-11-03

Family

ID=8105168

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97949999T DK0946538T3 (da) 1996-12-20 1997-12-19 Indan- eller dihydroindole derivater

Country Status (11)

Country Link
US (1) US6331544B1 (da)
EP (1) EP0946538B1 (da)
JP (1) JP2001506657A (da)
AT (1) ATE246683T1 (da)
AU (1) AU5311098A (da)
CA (1) CA2275299C (da)
DE (1) DE69724000T2 (da)
DK (1) DK0946538T3 (da)
ES (1) ES2205267T3 (da)
PT (1) PT946538E (da)
WO (1) WO1998028290A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1007523B9 (en) * 1997-07-25 2004-09-08 H. Lundbeck A/S Indole and 2,3-dihydroindole derivatives, their preparation and use
EP1228064A1 (en) * 1999-11-08 2002-08-07 Wyeth N-aryl-(homopiperazinyl)-cyclohexyl amines as 5-ht transporters
CN1802153A (zh) * 2002-10-22 2006-07-12 药物滥用科学研究公司 用选择性多巴胺d1受体激动剂治疗认知损害

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2692264B1 (fr) 1992-06-12 1994-08-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
ZA954689B (en) 1994-06-08 1996-01-29 Lundbeck & Co As H 4-Aryl-1-(indanmethyl dihydrobenzofuranmethyl or dihydrobenzothiophenemethyl) piperidines tetrahydropyridines or piperazines
FR2734819B1 (fr) * 1995-05-31 1997-07-04 Adir Nouveaux composes de la piperazine, de la piperidine et de la 1,2,5,6-tetrahydropyridine, leur procede de preparation et les compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
US6331544B1 (en) 2001-12-18
EP0946538A1 (en) 1999-10-06
DE69724000D1 (de) 2003-09-11
CA2275299A1 (en) 1998-07-02
JP2001506657A (ja) 2001-05-22
ES2205267T3 (es) 2004-05-01
DE69724000T2 (de) 2004-07-22
CA2275299C (en) 2003-12-16
AU5311098A (en) 1998-07-17
WO1998028290A1 (en) 1998-07-02
ATE246683T1 (de) 2003-08-15
PT946538E (pt) 2003-12-31
EP0946538B1 (en) 2003-08-06

Similar Documents

Publication Publication Date Title
ATE166650T1 (de) Spiroazacyclischderivate als substanz p antagonisten
PT641328E (pt) Derivados aza-biciclicos em ponte como antagonistas da substancia p
DE69725171D1 (de) Substituierte pyrrolylverbindungen zur behandlung von entzündungen
ATE269312T1 (de) N-(amidinophenyl)-n'-(subst.)-3h-2,4- benzodiazepin-3-on derivative als faktor xa inhibitoren
DE69926919D1 (de) N-ureidoalkylpiperidine als modulatoren der aktivität der chemokinrezeptoren
TR200101969T2 (tr) Enflamasyon tedavisi için sübstitüe edilmiş benzopiran analogları.
EA199700156A1 (ru) Производные индола как антагонисты рецептора 5-нт
DE69516866D1 (de) Stereochemische wortmanninderivate
ES2179273T3 (es) N-bencil-2-fenilindolas como agentes estrogenicos.
DE69705829D1 (de) Meta-substituierte phenylsulphonamidderivate
NO20000521D0 (no) 1-(N-fenylaminoalkyl)-piperazin derivater substituert i posisjon 2 på fenylringen
ATE247639T1 (de) Arylsubstituierte cyclische amine als selektive dopamin-d3-liganden
ATE206708T1 (de) Benzimidazolonderivate mit zentraler dopaminerger aktivität
ATE264268T1 (de) Verfahren zur herstellung von zsm-5 und zsm-11
ES2073258T3 (es) Nuevos derivados de la urea, su preparacion y su aplicacion en terapeutica.
TR199500956A2 (tr) Benzimidazol türevleri.
ES2174113T3 (es) Nuevos derivados de ((3-alcoxi-fenoxi)-etil)-dialquilamina y su utilizacion como anestesicos locales.
DE69724000D1 (de) Indan- oder dihydroindol-derivate
CA2241845A1 (en) 4,5-dihydronaphth[1,2-c]isoxazoles and derivatives thereof having cns activity
DE69604976D1 (de) Herstellung von Diamanteinkristallen aus amorphen hydrogenierten Kohlstoff
NO974155L (no) Ny fremgangsmåte for fremstilling av 2,3-dihydrobenzofuranolderivater
NO962620L (no) Nye mellomprodukter for syntese av L-aspartyl-D--aminoalkanoyl-(S)-N--alkylbenzylamider anvendbare son kunstige sötningsmidler
DE69808922D1 (de) Thiazolobenzoheterocyclen, ihre herstellung und diese enthaltende phatrmazeutische zubereitungen
ATE243695T1 (de) 5-bicycloindolverbindungen
ATE199547T1 (de) Arylalkoxyphenoxyimidazolinverbindungen