DK0837680T3 - Anvendelse af phenoxy-pyridinderivater til behandling af sygdomme, som forårsages af forstyrrelser i dopaminsystemet - Google Patents
Anvendelse af phenoxy-pyridinderivater til behandling af sygdomme, som forårsages af forstyrrelser i dopaminsystemetInfo
- Publication number
- DK0837680T3 DK0837680T3 DK96921928T DK96921928T DK0837680T3 DK 0837680 T3 DK0837680 T3 DK 0837680T3 DK 96921928 T DK96921928 T DK 96921928T DK 96921928 T DK96921928 T DK 96921928T DK 0837680 T3 DK0837680 T3 DK 0837680T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- carbonyl
- amino
- hydrogen
- phenoxy
- Prior art date
Links
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 title abstract 4
- 229960003638 dopamine Drugs 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 2
- MEAAWTRWNWSLPF-UHFFFAOYSA-N 2-phenoxypyridine Chemical class C=1C=CC=NC=1OC1=CC=CC=C1 MEAAWTRWNWSLPF-UHFFFAOYSA-N 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 150000002431 hydrogen Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000006598 aminocarbonylamino group Chemical group 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 239000012876 carrier material Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- -1 lower-alkyl Inorganic materials 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH170495 | 1995-06-09 | ||
| PCT/EP1996/002430 WO1996041629A1 (en) | 1995-06-09 | 1996-06-04 | Use of phenoxy pyridine derivatives for the treatment of illnesses caused by disorders of the dopamine system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0837680T3 true DK0837680T3 (da) | 2001-05-07 |
Family
ID=4216657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96921928T DK0837680T3 (da) | 1995-06-09 | 1996-06-04 | Anvendelse af phenoxy-pyridinderivater til behandling af sygdomme, som forårsages af forstyrrelser i dopaminsystemet |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5698565A (da) |
| EP (1) | EP0837680B1 (da) |
| JP (1) | JP3004732B2 (da) |
| AT (1) | ATE198984T1 (da) |
| AU (1) | AU6300396A (da) |
| BR (1) | BR9609196A (da) |
| CA (1) | CA2222226A1 (da) |
| DE (1) | DE69611727T2 (da) |
| DK (1) | DK0837680T3 (da) |
| ES (1) | ES2154828T3 (da) |
| GR (1) | GR3035703T3 (da) |
| PT (1) | PT837680E (da) |
| TR (1) | TR199701577T1 (da) |
| WO (1) | WO1996041629A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9708171A (pt) * | 1996-03-08 | 1999-07-27 | Hoffmann La Roche | Uso de derivados de 4-fenil-3,6-di-hidro-2h-piridila como bloqueadores de subtipo de receptor nmda |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL133317C (da) * | 1966-06-24 | 1900-01-01 | ||
| US3816434A (en) * | 1966-06-24 | 1974-06-11 | Hoffmann La Roche | 4-(3-(4-phenyl-piperidino)-2-hydroxy-propoxy)-benzophenones |
| CH474511A (da) * | 1966-06-24 | 1969-06-30 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | |
| CH507240A (de) * | 1968-12-24 | 1971-05-15 | Hoffmann La Roche | Verfahren zur Herstellung von aromatischen Äthern |
| CH558354A (de) * | 1970-06-17 | 1975-01-31 | Hoffmann La Roche | Verfahren zur herstellung von aromatischen aethern. |
| JPS57145872A (en) * | 1981-03-05 | 1982-09-09 | Otsuka Pharmaceut Co Ltd | Carbostyrile derivative |
| FR2662355B1 (fr) * | 1990-05-22 | 1994-11-10 | Sanofi Sa | Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux. |
| HU211019B (en) * | 1991-12-02 | 1995-09-28 | Richter Gedeon Vegyeszet | Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds |
-
1996
- 1996-04-29 US US08/639,386 patent/US5698565A/en not_active Expired - Fee Related
- 1996-06-04 ES ES96921928T patent/ES2154828T3/es not_active Expired - Lifetime
- 1996-06-04 DK DK96921928T patent/DK0837680T3/da active
- 1996-06-04 BR BR9609196A patent/BR9609196A/pt not_active Application Discontinuation
- 1996-06-04 JP JP9502585A patent/JP3004732B2/ja not_active Expired - Lifetime
- 1996-06-04 AT AT96921928T patent/ATE198984T1/de not_active IP Right Cessation
- 1996-06-04 DE DE69611727T patent/DE69611727T2/de not_active Expired - Fee Related
- 1996-06-04 PT PT96921928T patent/PT837680E/pt unknown
- 1996-06-04 TR TR97/01577T patent/TR199701577T1/xx unknown
- 1996-06-04 AU AU63003/96A patent/AU6300396A/en not_active Abandoned
- 1996-06-04 CA CA002222226A patent/CA2222226A1/en not_active Abandoned
- 1996-06-04 EP EP96921928A patent/EP0837680B1/en not_active Expired - Lifetime
- 1996-06-04 WO PCT/EP1996/002430 patent/WO1996041629A1/en not_active Ceased
-
2001
- 2001-04-05 GR GR20010400551T patent/GR3035703T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10506651A (ja) | 1998-06-30 |
| DE69611727T2 (de) | 2001-08-23 |
| EP0837680B1 (en) | 2001-01-31 |
| US5698565A (en) | 1997-12-16 |
| ES2154828T3 (es) | 2001-04-16 |
| WO1996041629A1 (en) | 1996-12-27 |
| CA2222226A1 (en) | 1996-12-27 |
| MX9709393A (es) | 1998-07-31 |
| JP3004732B2 (ja) | 2000-01-31 |
| BR9609196A (pt) | 1999-05-11 |
| ATE198984T1 (de) | 2001-02-15 |
| PT837680E (pt) | 2001-07-31 |
| DE69611727D1 (de) | 2001-03-08 |
| TR199701577T1 (xx) | 1998-06-22 |
| AU6300396A (en) | 1997-01-09 |
| EP0837680A1 (en) | 1998-04-29 |
| GR3035703T3 (en) | 2001-07-31 |
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