DK0831879T3 - Fremgangsmåde til identifikation eller isolering af et molekyle, samt derved identificerede molekyler - Google Patents
Fremgangsmåde til identifikation eller isolering af et molekyle, samt derved identificerede molekylerInfo
- Publication number
- DK0831879T3 DK0831879T3 DK96919266T DK96919266T DK0831879T3 DK 0831879 T3 DK0831879 T3 DK 0831879T3 DK 96919266 T DK96919266 T DK 96919266T DK 96919266 T DK96919266 T DK 96919266T DK 0831879 T3 DK0831879 T3 DK 0831879T3
- Authority
- DK
- Denmark
- Prior art keywords
- identifying
- host cells
- molecule
- lysates
- sample
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56977—HLA or MHC typing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/479,328 US5698396A (en) | 1995-06-07 | 1995-06-07 | Method for identifying auto-immunoreactive substances from a subject |
| US08/580,980 US6025191A (en) | 1995-06-07 | 1996-01-03 | Isolated nucleic acid molecules which encode a melanoma specific antigen and uses thereof |
| US08/644,116 US6140464A (en) | 1995-06-07 | 1996-05-10 | Nonapeptides that bind a HLA-A2.1 molecule |
| PCT/US1996/009726 WO1996040209A1 (fr) | 1995-06-07 | 1996-06-07 | Procede d'identification ou d'isolation d'une molecule et molecules ainsi identifiees |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0831879T3 true DK0831879T3 (da) | 2002-12-16 |
Family
ID=23903564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96919266T DK0831879T3 (da) | 1995-06-07 | 1996-06-07 | Fremgangsmåde til identifikation eller isolering af et molekyle, samt derved identificerede molekyler |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US5698396A (fr) |
| EP (1) | EP0831879B1 (fr) |
| JP (1) | JP2002502354A (fr) |
| CN (1) | CN1136914C (fr) |
| AT (2) | ATE222116T1 (fr) |
| CA (1) | CA2223566C (fr) |
| DE (2) | DE69627056T2 (fr) |
| DK (1) | DK0831879T3 (fr) |
| ES (1) | ES2180782T3 (fr) |
| PT (1) | PT831879E (fr) |
| WO (1) | WO1996040209A1 (fr) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5589579A (en) * | 1994-07-19 | 1996-12-31 | Cytoclonal Pharmaceutics, Inc. | Gene sequence and probe for a marker of non-small cell lung carinoma |
| US20010053523A1 (en) * | 1995-06-02 | 2001-12-20 | M&E Biotech A/S. | Method for identification of biologically active peptides and nucleic acids |
| AU725716C (en) | 1996-01-23 | 2003-02-20 | Board Of Trustees Of The Leland Stanford Junior University | Methods for screening for transdominant effector peptides and RNA molecules |
| US6365344B1 (en) * | 1996-01-23 | 2002-04-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for screening for transdominant effector peptides and RNA molecules |
| US6027916A (en) | 1996-10-09 | 2000-02-22 | Human Genome Sciences, Inc. | Galectin 9 and 10SV Polynucleotides |
| US6287756B1 (en) * | 1997-05-05 | 2001-09-11 | Ludwig Institute For Cancer Research | Methods for determining presence of cancer in a sample by determining expression of an SSX gene |
| US6548064B1 (en) * | 1997-05-05 | 2003-04-15 | Ludwig Institute For Cancer Research | Isolated peptides consisting of amino acid sequences found in SSX or NY-ESO-1 molecules, which bind to HLA molecules |
| US6977074B2 (en) * | 1997-07-10 | 2005-12-20 | Mannkind Corporation | Method of inducing a CTL response |
| US6994851B1 (en) | 1997-07-10 | 2006-02-07 | Mannkind Corporation | Method of inducing a CTL response |
| US6043084A (en) * | 1997-10-10 | 2000-03-28 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules associated with colon cancer and methods for diagnosing and treating colon cancer |
| US6403373B1 (en) | 1997-10-10 | 2002-06-11 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules associated with colon, renal, and stomach cancer and methods of using these |
| US6218521B1 (en) | 1997-07-17 | 2001-04-17 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules associated with gastric cancer and methods for diagnosing and treating gastric cancer |
| US20030138808A1 (en) * | 1998-02-19 | 2003-07-24 | Simard John J.L. | Expression vectors encoding epitopes of target-associated antigens |
| US6140050A (en) * | 1998-06-26 | 2000-10-31 | Ludwig Institute For Cancer Research | Methods for determining breast cancer and melanoma by assaying for a plurality of antigens associated therewith |
| US6440663B1 (en) | 1998-10-05 | 2002-08-27 | Ludwig Institute For Cancer Research | Renal cancer associated antigens and uses therefor |
| WO2001000874A2 (fr) | 1999-06-30 | 2001-01-04 | Ludwig Institute For Cancer Research | Antigenes associes au cancer et leurs utilisations |
| WO2001047959A2 (fr) | 1999-11-30 | 2001-07-05 | Ludwig Institute For Cancer Research | Molecules d'acides nucleiques isoles codant pour des antigenes associes au cancers, ces antigenes et leur utilisation |
| WO2001053349A2 (fr) * | 2000-01-21 | 2001-07-26 | Ludwig Institute For Cancer Research | Antigenes associes au cancer du poumon a petites cellules et utilisations de ces antigenes |
| US6448073B1 (en) | 2000-01-28 | 2002-09-10 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof |
| US20030215425A1 (en) * | 2001-12-07 | 2003-11-20 | Simard John J. L. | Epitope synchronization in antigen presenting cells |
| ES2347762T3 (es) * | 2000-04-28 | 2010-11-04 | Mannkind Corporation | Sincronizacion de epitopos en celulas que presentan antigenos. |
| US6861234B1 (en) * | 2000-04-28 | 2005-03-01 | Mannkind Corporation | Method of epitope discovery |
| PT1914305E (pt) * | 2000-07-27 | 2010-01-29 | Novartis Vaccines & Diagnostic | Polipéptidos gsk3 |
| US20040086852A1 (en) * | 2000-12-01 | 2004-05-06 | Toshiro Ono | Cancer associated antigens and uses therefor |
| US20030044813A1 (en) * | 2001-03-30 | 2003-03-06 | Old Lloyd J. | Cancer-testis antigens |
| EP1453471B1 (fr) * | 2001-11-07 | 2011-01-05 | Mannkind Corporation | Vecteurs d'expression codant pour des epitopes d'antigenes et procedes permettant leur conception |
| EP2110669B1 (fr) | 2002-06-13 | 2011-08-03 | Merck Patent GmbH | Procédés d'identification d'allo-antigènes et leur utilisation dans la thérapie anticancéreuse et la transplantation |
| US8177823B2 (en) * | 2005-06-30 | 2012-05-15 | Depuy Spine Sarl | Orthopedic clamping hook assembly |
| US8672732B2 (en) * | 2006-01-19 | 2014-03-18 | Schneider Electric It Corporation | Cooling system and method |
| AU2007272785A1 (en) * | 2006-07-14 | 2008-01-17 | Mannkind Corporation | Methods to elicit, enhance and sustain immune responses against MHC class-I restricted epitopes, for prophylactic or therapeutic purposes |
| ES2527412T3 (es) * | 2007-02-15 | 2015-01-23 | Mannkind Corporation | Método para aumentar la respuesta de los linfocitos T |
| US20090131355A1 (en) * | 2007-05-23 | 2009-05-21 | Adrian Ion Bot | Multicistronic vectors and methods for their design |
| CN104873962B (zh) | 2007-10-25 | 2019-04-26 | 东丽株式会社 | 免疫诱导剂 |
| MX2011000117A (es) | 2008-07-10 | 2011-02-25 | Toray Industries | Composicion farmaceutica para tratamiento y prevencion de cancer. |
| DK2733492T3 (en) * | 2008-08-05 | 2016-04-25 | Toray Industries | Method for detection of cancer |
| AU2009278386B2 (en) | 2008-08-05 | 2015-05-21 | Toray Industries, Inc. | Pharmaceutical composition for treatment and prevention of cancers |
| KR20160127146A (ko) | 2008-08-05 | 2016-11-02 | 도레이 카부시키가이샤 | 면역 유도제 |
| US8691510B2 (en) * | 2008-11-07 | 2014-04-08 | Sequenta, Inc. | Sequence analysis of complex amplicons |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| GB2467704B (en) * | 2008-11-07 | 2011-08-24 | Mlc Dx Inc | A method for determining a profile of recombined DNA sequences in T-cells and/or B-cells |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| PL2387627T3 (pl) | 2009-01-15 | 2016-10-31 | Profilowanie odporności adaptacyjnej i wytwarzanie przeciwciał monoklonalnych | |
| BRPI1009873A2 (pt) | 2009-03-17 | 2016-03-08 | Glaxosmithkline Biolog Sa | detecção aperfeiçoada de expressão gênica |
| KR20120044941A (ko) | 2009-06-25 | 2012-05-08 | 프레드 헛친슨 켄서 리서치 센터 | 적응 면역의 측정방법 |
| MX2012004721A (es) | 2009-10-23 | 2012-06-25 | Mannkind Corp | Inmunoterapia de cancer y metodo de tratamiento. |
| US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
| ES2583777T3 (es) | 2010-02-04 | 2016-09-22 | Toray Industries, Inc. | Composición farmacéutica que comprende anticuerpos anti CAPRIN-1 para el tratamiento y/o la prevención del cáncer |
| PL2532366T3 (pl) | 2010-02-04 | 2017-02-28 | Toray Industries, Inc. | Kompozycja farmaceutyczna do leczenia i/lub zapobiegania nowotworowi |
| RU2603742C2 (ru) | 2010-02-04 | 2016-11-27 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики рака |
| US9180187B2 (en) | 2010-02-04 | 2015-11-10 | Toray Industries, Inc. | Medicament for treating and/or preventing cancer |
| BR112012019098B8 (pt) | 2010-02-04 | 2021-08-17 | Toray Industries | anticorpo, composição farmacêutica, combinação farmacêutica e usos de um anticorpo, de uma composição farmacêutica e de uma combinação farmacêutica |
| CN102821788B (zh) | 2010-02-04 | 2016-11-16 | 东丽株式会社 | 癌的治疗和/或预防用药物组合物 |
| KR101988895B1 (ko) | 2011-05-19 | 2019-06-13 | 도레이 카부시키가이샤 | 면역 유도제 |
| AU2012256757B2 (en) | 2011-05-19 | 2017-06-15 | Toray Industries, Inc. | Immunity inducing agent |
| MX351682B (es) | 2011-08-04 | 2017-10-25 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
| EP2740798B1 (fr) | 2011-08-04 | 2016-12-07 | Toray Industries, Inc. | Composition de médicament pour traitement et/ou prévention du cancer |
| JP6015448B2 (ja) | 2011-08-04 | 2016-10-26 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
| CA2844040C (fr) | 2011-08-04 | 2019-05-07 | Toray Industries, Inc. | Composition pharmaceutique destinee a traiter ou a prevenir le cancer |
| MX351414B (es) | 2011-08-04 | 2017-10-13 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion de cancer pancreatico. |
| HUE030137T2 (en) | 2011-08-04 | 2017-04-28 | Toray Industries | Pharmaceutical preparation for the treatment and / or prevention of cancer |
| BR112014002616B1 (pt) | 2011-08-04 | 2022-01-18 | Toray Industries, Inc | Método para detectar câncer pancreático |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| CA2853088C (fr) | 2011-10-21 | 2018-03-13 | Adaptive Biotechnologies Corporation | Quantification de genomes de cellules immunitaires adaptatives dans un melange complexe de cellules |
| ES2867924T3 (es) | 2011-12-09 | 2021-10-21 | Adaptive Biotechnologies Corp | Diagnóstico de tumores malignos linfoides y detección de enfermedad residual mínima |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| WO2013125630A1 (fr) | 2012-02-21 | 2013-08-29 | 東レ株式会社 | Composition pharmaceutique pour le traitement et/ou la prévention du cancer |
| CA2864869C (fr) | 2012-02-21 | 2021-10-19 | Toray Industries, Inc. | Composition medicinale pour le traitement et/ou la prevention du cancer |
| DK2824114T3 (da) | 2012-02-21 | 2019-07-29 | Toray Industries | Farmaceutisk sammensætning til behandling af cancer |
| MX360208B (es) | 2012-02-21 | 2018-10-24 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
| ES2662128T3 (es) | 2012-03-05 | 2018-04-05 | Adaptive Biotechnologies Corporation | Determinación de cadenas de receptor inmunitario emparejadas a partir de la frecuencia de subunidades coincidentes |
| MX358224B (es) | 2012-03-30 | 2018-08-10 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion de cancer de higado. |
| KR102052400B1 (ko) | 2012-03-30 | 2019-12-06 | 도레이 카부시키가이샤 | 담낭암의 치료 및/또는 예방용 의약 조성물 |
| JP5756247B1 (ja) | 2012-05-08 | 2015-07-29 | アダプティブ バイオテクノロジーズ コーポレイション | マルチプレックスpcr反応における増幅バイアスを測定し校正する組成物及び方法 |
| EP2876446B1 (fr) | 2012-07-19 | 2018-12-26 | Toray Industries, Inc. | Procédé de détection de cancer |
| BR112015001100A2 (pt) | 2012-07-19 | 2018-03-27 | Toray Industries, Inc. | método de detecção de câncer |
| ES2660027T3 (es) | 2012-10-01 | 2018-03-20 | Adaptive Biotechnologies Corporation | Evaluación de la inmunocompetencia por la diversidad de los receptores de inmunidad adaptativa y caracterización de la clonalidad |
| WO2015160439A2 (fr) | 2014-04-17 | 2015-10-22 | Adaptive Biotechnologies Corporation | Quantification de génomes de cellules de l'immunité acquise dans un mélange complexe de cellules |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| US9862774B2 (en) | 2013-08-09 | 2018-01-09 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| EP3114240B1 (fr) | 2014-03-05 | 2019-07-24 | Adaptive Biotechnologies Corporation | Procédés dans lesquels on utilise des molécules synthétiques contenant des randomères |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| AU2015339191A1 (en) | 2014-10-29 | 2017-05-18 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| DK3290051T3 (da) | 2015-04-30 | 2020-01-06 | Toray Industries | Farmaceutisk sammensætning til behandling og/eller forebyggelse af cancer |
| EP3290048B1 (fr) | 2015-04-30 | 2020-09-23 | Toray Industries, Inc. | Agent inducteur de l'immunité |
| CN107604092A (zh) * | 2017-11-01 | 2018-01-19 | 中国医学科学院药用植物研究所 | 一种朝鲜淫羊藿与粗毛淫羊藿的分子鉴定方法 |
| CN107619876A (zh) * | 2017-11-01 | 2018-01-23 | 中国医学科学院药用植物研究所 | 一种箭叶淫羊藿与天平山淫羊藿的分子鉴定方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5583024A (en) * | 1985-12-02 | 1996-12-10 | The Regents Of The University Of California | Recombinant expression of Coleoptera luciferase |
| US5274087A (en) * | 1986-08-13 | 1993-12-28 | Molecular Diagnostics, Inc. | cDNA coding for carcinoembryonic antigen (CEA) |
| CA2079105C (fr) * | 1990-04-04 | 2000-06-13 | Michael Houghton | Protease du virus de l'hepatite c |
| AT401180B (de) * | 1990-08-13 | 1996-07-25 | Biomay Biotech Prod | Für das baumpollenallergen p14 codierende rekombinante dna-moleküle, daraus hergestellte und abgeleitete polypeptide und deren verwendung |
| US5342774A (en) * | 1991-05-23 | 1994-08-30 | Ludwig Institute For Cancer Research | Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1 |
| US5405940A (en) * | 1992-08-31 | 1995-04-11 | Ludwig Institute For Cancer Research | Isolated nonapeptides derived from MAGE genes and uses thereof |
| US5585464A (en) * | 1993-02-19 | 1996-12-17 | Theratech, Inc. | Recombinant antigen for diagnosing rheumatoid arthritis |
| CN1118572A (zh) * | 1993-03-05 | 1996-03-13 | 萨依特尔有限公司 | Hla-a2.1组合肽及其用途 |
| FR2705362B1 (fr) * | 1993-05-18 | 1995-08-04 | Agronomique Inst Nat Rech | Clônage et expression du gêne de l'enzyme malolactique de Lactococcus lactis. |
| WO1995014772A1 (fr) * | 1993-11-12 | 1995-06-01 | Kenichi Matsubara | Signature genique |
| US5589579A (en) * | 1994-07-19 | 1996-12-31 | Cytoclonal Pharmaceutics, Inc. | Gene sequence and probe for a marker of non-small cell lung carinoma |
-
1995
- 1995-06-07 US US08/479,328 patent/US5698396A/en not_active Expired - Fee Related
-
1996
- 1996-06-07 DE DE69627056T patent/DE69627056T2/de not_active Expired - Lifetime
- 1996-06-07 ES ES96919266T patent/ES2180782T3/es not_active Expired - Lifetime
- 1996-06-07 CN CNB961956380A patent/CN1136914C/zh not_active Expired - Lifetime
- 1996-06-07 WO PCT/US1996/009726 patent/WO1996040209A1/fr not_active Ceased
- 1996-06-07 AT AT96919266T patent/ATE222116T1/de active
- 1996-06-07 JP JP50197297A patent/JP2002502354A/ja not_active Ceased
- 1996-06-07 DK DK96919266T patent/DK0831879T3/da active
- 1996-06-07 PT PT96919266T patent/PT831879E/pt unknown
- 1996-06-07 EP EP96919266A patent/EP0831879B1/fr not_active Expired - Lifetime
- 1996-06-07 AT AT00117699T patent/ATE235248T1/de not_active IP Right Cessation
- 1996-06-07 CA CA002223566A patent/CA2223566C/fr not_active Expired - Lifetime
- 1996-06-07 DE DE69623014T patent/DE69623014T2/de not_active Expired - Lifetime
- 1996-12-06 US US08/761,119 patent/US5798264A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69623014D1 (de) | 2002-09-19 |
| ATE235248T1 (de) | 2003-04-15 |
| CA2223566C (fr) | 2002-09-03 |
| EP0831879A1 (fr) | 1998-04-01 |
| CA2223566A1 (fr) | 1996-12-19 |
| JP2002502354A (ja) | 2002-01-22 |
| ATE222116T1 (de) | 2002-08-15 |
| AU704109B2 (en) | 1999-04-15 |
| PT831879E (pt) | 2002-12-31 |
| EP0831879B1 (fr) | 2002-08-14 |
| AU6165296A (en) | 1996-12-30 |
| CN1190894A (zh) | 1998-08-19 |
| CN1136914C (zh) | 2004-02-04 |
| US5798264A (en) | 1998-08-25 |
| DE69623014T2 (de) | 2003-05-08 |
| US5698396A (en) | 1997-12-16 |
| DE69627056T2 (de) | 2004-01-29 |
| ES2180782T3 (es) | 2003-02-16 |
| WO1996040209A1 (fr) | 1996-12-19 |
| EP0831879A4 (fr) | 2000-01-26 |
| DE69627056D1 (de) | 2003-04-30 |
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