DK0813411T3 - Anvendelse af vincopetinderivater til hæmning af dannelse eller afsondring af amyloid -protein - Google Patents
Anvendelse af vincopetinderivater til hæmning af dannelse eller afsondring af amyloid -proteinInfo
- Publication number
- DK0813411T3 DK0813411T3 DK96901960T DK96901960T DK0813411T3 DK 0813411 T3 DK0813411 T3 DK 0813411T3 DK 96901960 T DK96901960 T DK 96901960T DK 96901960 T DK96901960 T DK 96901960T DK 0813411 T3 DK0813411 T3 DK 0813411T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- optionally substituted
- secretion
- date
- vincopetine
- Prior art date
Links
- 230000028327 secretion Effects 0.000 title abstract 2
- 102000009091 Amyloidogenic Proteins Human genes 0.000 title 1
- 108010048112 Amyloidogenic Proteins Proteins 0.000 title 1
- 230000014616 translation Effects 0.000 title 1
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2668795 | 1995-02-15 | ||
| PCT/JP1996/000265 WO1996025161A1 (en) | 1995-02-15 | 1996-02-08 | Use of vinpocetine derivatives for inhibiting production or secretion of amyloid beta protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0813411T3 true DK0813411T3 (da) | 2002-05-13 |
Family
ID=12200316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96901960T DK0813411T3 (da) | 1995-02-15 | 1996-02-08 | Anvendelse af vincopetinderivater til hæmning af dannelse eller afsondring af amyloid -protein |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5965568A (da) |
| EP (1) | EP0813411B1 (da) |
| AT (1) | ATE212227T1 (da) |
| AU (1) | AU4632996A (da) |
| CA (1) | CA2213094A1 (da) |
| DE (1) | DE69618765T2 (da) |
| DK (1) | DK0813411T3 (da) |
| ES (1) | ES2171646T3 (da) |
| HU (1) | HUP9801155A3 (da) |
| PT (1) | PT813411E (da) |
| WO (1) | WO1996025161A1 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000024392A1 (en) * | 1998-10-26 | 2000-05-04 | Sumitomo Pharmaceuticals Company, Limited | β-AMYLOID FORMATION INHIBITORS |
| US8153646B2 (en) * | 2000-08-10 | 2012-04-10 | Dart Neuroscience (Cayman) Ltd. | Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation |
| EP1355669B1 (en) * | 2000-08-10 | 2011-09-28 | Cold Spring Harbor Laboratory | Augmented cognitive training |
| WO2004047854A2 (en) * | 2002-11-22 | 2004-06-10 | Novartis Ag | Methods for the treatment of alzheimers disease and compositions therefore |
| CA2544035C (en) * | 2003-10-28 | 2012-01-10 | Universidad Nacional Autonoma De Mexico | Utilization of vinpocetine to avoid complications in particular those associated to hearing which occur with epilepsy, and treatment thereof |
| RU2376990C2 (ru) * | 2003-10-28 | 2009-12-27 | Универсидад Насиональ Аутонома Де Мексико | Применение винпоцетина для предупреждения осложнений, в частности осложнений, связанных со слухом, которые сопутствуют эпилепсии и ее лечению |
| GB0329498D0 (en) * | 2003-12-19 | 2004-01-28 | Novartis Ag | Organic compounds |
| JP2007528892A (ja) * | 2004-03-12 | 2007-10-18 | エギシュ ヂョヂセルヂャール エンニュ・エル・テー | 認知機能の減退を阻止するための複合医薬組成物 |
| JP5160764B2 (ja) | 2006-10-13 | 2013-03-13 | 全薬工業株式会社 | 特定の構造の複素環化合物を含む抗鬱剤、脳保護剤、アミロイドβ沈着抑制剤または老化抑制剤 |
| KR101095026B1 (ko) * | 2009-01-23 | 2011-12-20 | 한국과학기술연구원 | 비스(스티릴)피리미딘 및 비스(스티릴)벤젠 유도체, 이의 약학적으로 허용 가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 베타아밀로이드 집적 관련 질환의 예방 또는 치료용 약학적 조성물 |
| WO2010103539A2 (en) | 2009-03-09 | 2010-09-16 | Dinesh Shantilal Patel | Sustained release oral formulation of vinpocetine |
| CN102875547B (zh) * | 2011-07-15 | 2015-05-27 | 海南灵康制药有限公司 | 一种长春西汀化合物及其制法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4035370A (en) * | 1971-11-03 | 1977-07-12 | Richter Gedeon Vegyeszeti Gyar Rt. | Alkaloid esters |
| HU181941B (en) * | 1979-11-23 | 1983-11-28 | Richter Gedeon Vegyeszet | Process for producing apovincaminic acid ester derivatives |
| HU201674B (en) * | 1987-08-26 | 1990-12-28 | Richter Gedeon Vegyeszet | Process for producing pharmaceutical composition suitable for curing autoimmune-type leukoencephalomyelitic diseases e.g. sclerosis multiplex |
| JPH02167279A (ja) * | 1988-09-30 | 1990-06-27 | Taisho Pharmaceut Co Ltd | アポビンカミン酸誘導体 |
| JPH02152979A (ja) * | 1988-12-06 | 1990-06-12 | Taisho Pharmaceut Co Ltd | アポビンカミン酸誘導体 |
| JPH02204488A (ja) * | 1989-02-03 | 1990-08-14 | Taisho Pharmaceut Co Ltd | エブルナメニン誘導体 |
| JP3053913B2 (ja) * | 1991-07-15 | 2000-06-19 | 帝三製薬株式会社 | ビンポセチン類含有貼付剤 |
| US5296478A (en) * | 1992-10-07 | 1994-03-22 | The Dupont Merck Pharmaceutical Co. | 1-substituted oxindoles as cognition enhancers |
| WO1994017197A1 (fr) * | 1993-01-25 | 1994-08-04 | Takeda Chemical Industries, Ltd. | ANTICORPS DIRIGE CONTRE LE β-AMYLOIDE OU UN DERIVE DE CE DERNIER ET SON UTILISATION |
-
1996
- 1996-02-08 DK DK96901960T patent/DK0813411T3/da active
- 1996-02-08 AU AU46329/96A patent/AU4632996A/en not_active Abandoned
- 1996-02-08 AT AT96901960T patent/ATE212227T1/de not_active IP Right Cessation
- 1996-02-08 DE DE69618765T patent/DE69618765T2/de not_active Expired - Fee Related
- 1996-02-08 ES ES96901960T patent/ES2171646T3/es not_active Expired - Lifetime
- 1996-02-08 WO PCT/JP1996/000265 patent/WO1996025161A1/en not_active Ceased
- 1996-02-08 PT PT96901960T patent/PT813411E/pt unknown
- 1996-02-08 CA CA002213094A patent/CA2213094A1/en not_active Abandoned
- 1996-02-08 EP EP96901960A patent/EP0813411B1/en not_active Expired - Lifetime
- 1996-02-08 US US08/646,354 patent/US5965568A/en not_active Expired - Fee Related
- 1996-02-08 HU HU9801155A patent/HUP9801155A3/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2171646T3 (es) | 2002-09-16 |
| EP0813411A1 (en) | 1997-12-29 |
| ATE212227T1 (de) | 2002-02-15 |
| CA2213094A1 (en) | 1996-08-22 |
| EP0813411B1 (en) | 2002-01-23 |
| PT813411E (pt) | 2002-07-31 |
| AU4632996A (en) | 1996-09-04 |
| WO1996025161A1 (en) | 1996-08-22 |
| HUP9801155A3 (en) | 1999-03-01 |
| DE69618765T2 (de) | 2002-10-17 |
| US5965568A (en) | 1999-10-12 |
| DE69618765D1 (de) | 2002-03-14 |
| HUP9801155A2 (hu) | 1998-09-28 |
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