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DK0854707T3 - Faste lægemiddelformer, som opnåes ved ekstrusion af en isomalt indeholdende smeltet masse af en polymer og et biologisk virksomt stof - Google Patents

Faste lægemiddelformer, som opnåes ved ekstrusion af en isomalt indeholdende smeltet masse af en polymer og et biologisk virksomt stof

Info

Publication number
DK0854707T3
DK0854707T3 DK96934494T DK96934494T DK0854707T3 DK 0854707 T3 DK0854707 T3 DK 0854707T3 DK 96934494 T DK96934494 T DK 96934494T DK 96934494 T DK96934494 T DK 96934494T DK 0854707 T3 DK0854707 T3 DK 0854707T3
Authority
DK
Denmark
Prior art keywords
extrusion
isomal
polymer
active substance
biologically active
Prior art date
Application number
DK96934494T
Other languages
English (en)
Inventor
Juergen Zeidler
Joerg Rosenberg
Joerg Neumann
Joerg Breitenbach
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of DK0854707T3 publication Critical patent/DK0854707T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Indole Compounds (AREA)
DK96934494T 1995-09-29 1996-09-30 Faste lægemiddelformer, som opnåes ved ekstrusion af en isomalt indeholdende smeltet masse af en polymer og et biologisk virksomt stof DK0854707T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19536394A DE19536394A1 (de) 1995-09-29 1995-09-29 Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze
PCT/EP1996/004262 WO1997012603A1 (de) 1995-09-29 1996-09-30 Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze

Publications (1)

Publication Number Publication Date
DK0854707T3 true DK0854707T3 (da) 2002-12-16

Family

ID=7773633

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96934494T DK0854707T3 (da) 1995-09-29 1996-09-30 Faste lægemiddelformer, som opnåes ved ekstrusion af en isomalt indeholdende smeltet masse af en polymer og et biologisk virksomt stof

Country Status (22)

Country Link
US (1) US6187342B1 (da)
EP (1) EP0854707B1 (da)
JP (1) JP4041163B2 (da)
KR (1) KR19990063853A (da)
CN (1) CN1200694C (da)
AT (1) ATE228355T1 (da)
AU (1) AU7282896A (da)
BG (1) BG102346A (da)
BR (1) BR9610799A (da)
CA (1) CA2230950C (da)
CZ (1) CZ95998A3 (da)
DE (2) DE19536394A1 (da)
DK (1) DK0854707T3 (da)
ES (1) ES2187678T3 (da)
HU (1) HUP9903384A3 (da)
IL (1) IL123250A (da)
MX (1) MX9801988A (da)
NO (1) NO981394L (da)
RU (1) RU2197228C2 (da)
TW (1) TW438599B (da)
WO (1) WO1997012603A1 (da)
ZA (1) ZA968130B (da)

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US6465009B1 (en) 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
DE60028754T2 (de) * 1999-11-12 2007-05-31 Abbott Laboratories, Abbott Park Feste dispersion mit ritonavir, fenofibrat oder griseofulvin
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8088060B2 (en) * 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US20070141107A1 (en) * 2000-03-15 2007-06-21 Orbusneich Medical, Inc. Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
KR20040100835A (ko) * 2001-02-15 2004-12-02 킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨 안정된 제약및 갑상선 내분비 호르몬 구성물 및 그제조방법
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
EP1372392A4 (en) * 2001-03-26 2004-06-23 Smithkline Beecham Corp ORAL DOSAGE FORM CONTAINING NICOTINE
FR2823974B1 (fr) * 2001-04-25 2004-10-15 Pf Medicament Pastille medicamenteuse a liberation lente du principe actif
US20030190349A1 (en) * 2001-08-10 2003-10-09 Franz G. Andrew Methods of stabilizing pharmaceutical compositions
US20030180353A1 (en) * 2001-08-10 2003-09-25 Franz G. Andrew Stabilized pharmaceutical compositions
US20030198671A1 (en) * 2001-08-10 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique plasma AUC properties
US20030198667A1 (en) * 2001-08-10 2003-10-23 Franz Andrew G. Methods of producing dispersible pharmaceutical compositions
US20030195253A1 (en) * 2001-08-14 2003-10-16 Franz G. Andrew Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
US20030199587A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique Cmax properties
US20030203967A1 (en) * 2001-08-14 2003-10-30 Franz G. Andrew Levothyroxine compositions having unique Tmax properties
US20030198672A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique triidothyronine plasma AUC properties
US20030199586A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Unique levothyroxine aqueous materials
US20030190359A1 (en) * 2001-10-29 2003-10-09 Franz G. Andrew Levothyroxine compositions having unique triiodothyronine Tmax properties
KR100514590B1 (ko) * 2001-12-18 2005-09-14 주식회사 대웅 프라바스타틴나트륨 및 안정화제로서의 코폴리비돈을함유하는 약제 조성물
US20040101543A1 (en) * 2002-03-22 2004-05-27 John Liu Nicotine-containing oral dosage form
CN100473378C (zh) * 2002-12-17 2009-04-01 阿伯特有限及两合公司 包含非诺贝酸、其生理可接受的盐或衍生物的制剂
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
CN100594023C (zh) * 2003-02-03 2010-03-17 诺瓦提斯公司 药物制剂
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
GB2418854B (en) * 2004-08-31 2009-12-23 Euro Celtique Sa Multiparticulates
RU2276985C1 (ru) * 2004-10-07 2006-05-27 Открытое акционерное общество "Щелковский витаминный завод" Фармацевтическая композиция для лечения заболеваний поджелудочной железы и расстройств пищеварения, связанных с заболеванием печени
NZ569813A (en) * 2005-12-16 2011-07-29 Hanmi Holdings Co Ltd Solid dispersion comprising an active ingredient having a low melting point and an absorbent, and a tablet for oral administration comprising same
EP2140861A1 (en) * 2008-06-30 2010-01-06 Abbott GmbH & Co. KG Pharmaceutical dosage form comprising polymeric carrier composition
JP2014503470A (ja) * 2010-10-14 2014-02-13 アボット ゲーエムベーハー ウント カンパニー カーゲー クルクミノイド固体分散製剤
BR112013023879B1 (pt) 2011-03-21 2022-08-30 Boehringer Ingelheim International Gmbh Preparações sólidas que contém ambroxol, seu método de preparação, forma de dosagem farmacêutica e seus usos
US9375033B2 (en) 2014-02-14 2016-06-28 R.J. Reynolds Tobacco Company Tobacco-containing gel composition
ES2992002T3 (es) * 2016-04-06 2024-12-05 Astellas Pharma Inc Moldeo tridimensional de elución rápida, filamento para moldeo tridimensional de elución rápida y material para moldeo tridimensional de elución rápida

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DE3314003A1 (de) * 1983-04-18 1984-10-18 Boehringer Ingelheim KG, 6507 Ingelheim Teilbare tablette mit verzoegerter wirkstofffreigabe und verfahren zu deren herstellung
DE3612211A1 (de) 1986-04-11 1987-10-15 Basf Ag Kontinuierliches verfahren zum tablettieren
DE3826946C1 (da) * 1988-08-09 1990-03-15 A. Nattermann & Cie Gmbh, 5000 Koeln, De
ATE221772T1 (de) * 1994-06-14 2002-08-15 Biovail Tech Ltd Verfahren und apparat zur herstellung von schnelllöslichen dosierungseinheiten und daraus erhältliches produkt

Also Published As

Publication number Publication date
BG102346A (bg) 1998-10-30
EP0854707B1 (de) 2002-11-27
US6187342B1 (en) 2001-02-13
EP0854707A1 (de) 1998-07-29
JP4041163B2 (ja) 2008-01-30
ATE228355T1 (de) 2002-12-15
NO981394D0 (no) 1998-03-27
WO1997012603A1 (de) 1997-04-10
CN1198094A (zh) 1998-11-04
CZ95998A3 (cs) 1998-08-12
NO981394L (no) 1998-03-27
CA2230950A1 (en) 1997-04-10
MX9801988A (es) 1998-08-30
CN1200694C (zh) 2005-05-11
DE59609923D1 (de) 2003-01-09
TW438599B (en) 2001-06-07
RU2197228C2 (ru) 2003-01-27
JPH11512729A (ja) 1999-11-02
ZA968130B (en) 1998-03-27
AU7282896A (en) 1997-04-28
ES2187678T3 (es) 2003-06-16
BR9610799A (pt) 1999-07-13
IL123250A (en) 2000-08-31
CA2230950C (en) 2007-12-04
KR19990063853A (ko) 1999-07-26
HUP9903384A3 (en) 2001-04-28
IL123250A0 (en) 1998-09-24
DE19536394A1 (de) 1997-04-03
HUP9903384A2 (hu) 2000-10-28

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