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DK0785773T3 - Etherlipidliposomer og deres terapeutiske anvendelse - Google Patents

Etherlipidliposomer og deres terapeutiske anvendelse

Info

Publication number
DK0785773T3
DK0785773T3 DK95935710T DK95935710T DK0785773T3 DK 0785773 T3 DK0785773 T3 DK 0785773T3 DK 95935710 T DK95935710 T DK 95935710T DK 95935710 T DK95935710 T DK 95935710T DK 0785773 T3 DK0785773 T3 DK 0785773T3
Authority
DK
Denmark
Prior art keywords
liposomes
etherlipid
therapeutic use
phosphatidylethanolamine
underivatized
Prior art date
Application number
DK95935710T
Other languages
Danish (da)
English (en)
Inventor
Imran Ahmad
Eric Mayhew
Andrew S Janoff
Suresh K Bhatia
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of DK0785773T3 publication Critical patent/DK0785773T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK95935710T 1994-10-14 1995-10-12 Etherlipidliposomer og deres terapeutiske anvendelse DK0785773T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32304294A 1994-10-14 1994-10-14
PCT/US1995/012721 WO1996011670A1 (fr) 1994-10-14 1995-10-12 Liposomes comportant des lipides ethers et leur utilisation therapeutique

Publications (1)

Publication Number Publication Date
DK0785773T3 true DK0785773T3 (da) 2001-01-29

Family

ID=23257529

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95935710T DK0785773T3 (da) 1994-10-14 1995-10-12 Etherlipidliposomer og deres terapeutiske anvendelse

Country Status (15)

Country Link
US (1) US5762958A (fr)
EP (1) EP0785773B1 (fr)
JP (1) JPH10507450A (fr)
KR (1) KR100381449B1 (fr)
AT (1) ATE198419T1 (fr)
AU (1) AU707414B2 (fr)
CA (1) CA2199179A1 (fr)
DE (1) DE69519802T2 (fr)
DK (1) DK0785773T3 (fr)
ES (1) ES2153053T3 (fr)
FI (1) FI971494A0 (fr)
GR (1) GR3035689T3 (fr)
NO (1) NO316206B1 (fr)
PT (1) PT785773E (fr)
WO (1) WO1996011670A1 (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6007839A (en) * 1996-02-16 1999-12-28 The Liposome Company, Inc. Preparation of pharmaceutical compositions containing etherlipid-containing multiple lipid liposomes
USRE39042E1 (en) * 1996-02-16 2006-03-28 The Liposome Company, Inc. Etherlipid-containing multiple lipid liposomes
US5942246A (en) * 1996-02-16 1999-08-24 The Liposome Company, Inc. Etherlipid containing multiple lipid liposomes
US5965159A (en) * 1996-02-16 1999-10-12 The Liposome Company, Inc. Etherlipid-containing multiple lipid liposomes
US6667053B1 (en) 1996-02-16 2003-12-23 Elan Pharmaceuticals, Inc. D and L etherlipid stereoisomers and liposomes
US5932242A (en) * 1996-10-15 1999-08-03 The Liposome Company, Inc. Ether lipid-containing pharmaceutical compositions and therapeutic uses thereof
DE19829448A1 (de) * 1998-07-01 2000-10-12 Medmark Pharma Gmbh 1-Octadecyl-2-methyl-sn-glycero-3-phosphocholin (ET180CH3) zur Behandlung von humanen Mammakarzinomen
ES2154560B1 (es) * 1998-09-16 2001-12-01 Lipotec Sa Composicion a base de derivados de cromanos y su uso para reducir quimicamente las reacciones oxidativas o inducidas por radicales libres.
JP2002532553A (ja) 1998-12-21 2002-10-02 インケイサ．ソシエダ アノニマ 有害な胃腸副作用を引き起こさない有力な抗炎症剤としてのエーテルリゾリン脂質の使用
US7893226B2 (en) 2004-09-29 2011-02-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Use of lipid conjugates in the treatment of diseases
US9040078B2 (en) 2000-01-10 2015-05-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases of the nervous system
US8304395B2 (en) 2000-01-10 2012-11-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Lipid conjugates in the treatment of disease
US7608598B2 (en) 2000-01-10 2009-10-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of conjunctivitis
US8501701B2 (en) 2000-01-10 2013-08-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Use of lipid conjugates in the treatment of disease
US8916539B2 (en) 2000-01-10 2014-12-23 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of disease
US8076312B2 (en) 2000-01-10 2011-12-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Use of lipid conjugates in the treatment of disease
US7772196B2 (en) 2000-01-10 2010-08-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases
US8883761B2 (en) 2001-01-10 2014-11-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases associated with vasculature
WO2006042751A2 (fr) * 2004-10-19 2006-04-27 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Formulations contenant des alkylphosphocholines faisant intervenir de nouveaux porteurs de charge negatifs
CN101175499B (zh) * 2004-11-17 2010-12-22 耶路撒冷希伯来大学依苏姆研究发展公司 脂质结合物在制备治疗疾病药物中的用途
JP2006248978A (ja) * 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
US8906882B2 (en) 2005-11-17 2014-12-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Lipid conjugates in the treatment of allergic rhinitis
US8859524B2 (en) 2005-11-17 2014-10-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Lipid conjugates in the treatment of chronic rhinosinusitis
DE102006019907A1 (de) * 2006-04-28 2007-10-31 Müller-Enoch, Dieter, Prof. Dr. Verwendung von substituierten Glycerinderivaten zur Herstellung einer pharmazeutischen Zubereitung
CA2705785A1 (fr) 2006-11-14 2008-05-22 Saul Yedgar Utilisation de conjugues lipidiques dans le traitement de maladies ou de troubles oculaires
US8637688B2 (en) * 2006-12-20 2014-01-28 Julia Diederichs Topical dosage form comprising tri-substituted glycerol compounds
US9161944B2 (en) 2010-02-18 2015-10-20 Inserm (Institut National De La Sante Et De La Sante Et De La Recherche Medicale) Method for preventing cancer metastasis
US20150132369A1 (en) * 2013-11-09 2015-05-14 Exir Nano Sina Company Nanoliposomal cyclosorin formulations for immunosuppresion and methods for the production thereof
CN114469865B (zh) * 2022-03-17 2023-09-22 中国医学科学院输血研究所 一种与血细胞膜结合的脂质体药物载体及其制备方法和用途
ES3037760T3 (en) 2022-12-15 2025-10-06 Lifesome Therapeutics Sl Carrier as a multifunctional system

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2009343C3 (de) * 1970-02-27 1980-10-23 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Verwendung von Lysolecithinen als immunologische Adjuvantien
US4163748A (en) * 1973-09-06 1979-08-07 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Propane-1,3-diol phosphatides and method of preparing the same
US4159988A (en) * 1974-08-06 1979-07-03 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Synthetic phospholipids, a process for their manufacture and their use
DE2619686C2 (de) * 1976-05-04 1986-08-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Verwendung eines Lysolecithins zur Tumorbehandlung
DE3011738A1 (de) * 1980-03-26 1981-10-01 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Neue glycerin-3-phosphorsaeurehalogenalkylester
DE3239858A1 (de) * 1982-07-06 1984-01-12 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Neue d-mannitderivate als ausgangsprodukte zur synthese von phospholipiden
JPS5972294A (ja) * 1982-10-18 1984-04-24 Hisaji Nakamura スピ−カ装置
PH26160A (en) * 1985-08-19 1992-03-18 Univ Texas Pharmaceutical compositions consisting of acylated phospholipids
US4983397A (en) * 1985-08-19 1991-01-08 Board Of Regents, University Of Texas System Pharmaceutical compositions consisting of acylated phospholipids
US4920016A (en) * 1986-12-24 1990-04-24 Linear Technology, Inc. Liposomes with enhanced circulation time
US4965391A (en) * 1987-10-23 1990-10-23 The University Of Michigan Radioiodinated phospholipid ether analogues
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
DE4111105A1 (de) * 1991-04-05 1992-10-08 Max Planck Gesellschaft Neue erucyl-, brassidyl- und nervonylderivate
US5277913A (en) * 1991-09-09 1994-01-11 Thompson David H Liposomal delivery system with photoactivatable triggered release
DE4132345A1 (de) * 1991-09-27 1993-04-01 Max Planck Gesellschaft Ether-lysolecithine und alkylphosphocholine in liposomen
CA2122638C (fr) * 1991-10-23 2001-05-08 G. Dennis Sprott Formation de liposomes stables a partir d'extraits lipidiques d'archeobacteries
US5614214A (en) * 1993-05-21 1997-03-25 The Liposome Company, Inc. Reduction of liposome-induced adverse physiological reactions
DE4408011C1 (de) * 1994-03-10 1995-11-02 Max Delbrueck Centrum Pharmazeutisches Mittel zur Tumortherapie

Also Published As

Publication number Publication date
NO971643D0 (no) 1997-04-10
CA2199179A1 (fr) 1996-04-25
KR970705378A (ko) 1997-10-09
WO1996011670A1 (fr) 1996-04-25
FI971494L (fi) 1997-04-10
PT785773E (pt) 2001-05-31
FI971494A7 (fi) 1997-04-10
ATE198419T1 (de) 2001-01-15
EP0785773A1 (fr) 1997-07-30
NO316206B1 (no) 2003-12-29
EP0785773B1 (fr) 2001-01-03
ES2153053T3 (es) 2001-02-16
GR3035689T3 (en) 2001-07-31
JPH10507450A (ja) 1998-07-21
FI971494A0 (fi) 1997-04-10
AU707414B2 (en) 1999-07-08
US5762958A (en) 1998-06-09
NO971643L (no) 1997-06-09
DE69519802T2 (de) 2001-04-19
KR100381449B1 (ko) 2003-07-18
DE69519802D1 (de) 2001-02-08
AU3762595A (en) 1996-05-06

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