DK0629133T3 - Farmaceutisk anvendelse af peptidmetalioner - Google Patents

Farmaceutisk anvendelse af peptidmetalioner

Info

Publication number: DK0629133T3
Authority: DK; Denmark
Prior art keywords: metal ions; useful metal; medically useful; pharmaceutical use; biological
Prior art date: 1992-01-03

Application number

DK93902846T

Other languages

English (en)

Inventor

Buck A Rhodes

Paul O Zamora

Original Assignee

Rhomed Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-03

Filing date

1992-12-31

Publication date

2001-04-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27542230&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0629133(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1992-01-03 Priority claimed from US07/816,477 external-priority patent/US5460785A/en

1992-01-03 Priority claimed from US07/816,476 external-priority patent/US5346687A/en

1992-02-20 Priority claimed from US07/840,077 external-priority patent/US5443816A/en

1992-12-30 Priority claimed from US07/998,820 external-priority patent/US5738838A/en

1992-12-30 Priority claimed from US07/998,910 external-priority patent/US5556609A/en

1992-12-31 Application filed by Rhomed Inc filed Critical Rhomed Inc

2001-04-02 Application granted granted Critical

2001-04-02 Publication of DK0629133T3 publication Critical patent/DK0629133T3/da

Links

229910021645 metal ion Inorganic materials 0.000 title abstract 5
108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
230000008827 biological function Effects 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
XQQUSYWGKLRJRA-RABCQHRBSA-N (2s)-2-[[(2s)-2-[[(2s)-2-[[(2s)-6-amino-2-[[(2s,3s)-2-amino-3-methylpentanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-3-methylbutanoic acid Chemical compound CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O XQQUSYWGKLRJRA-RABCQHRBSA-N 0.000 abstract 1
MWOGMBZGFFZBMK-LJZWMIMPSA-N (2s)-2-[[(2s)-2-[[2-[[(2s,3s)-2-[[(2s)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid Chemical compound NC(N)=NCCC[C@@H](C(O)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](N)CC1=CC=C(O)C=C1 MWOGMBZGFFZBMK-LJZWMIMPSA-N 0.000 abstract 1
125000003275 alpha amino acid group Chemical group 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
108010088381 isoleucyl-lysyl-valyl-alanyl-valine Proteins 0.000 abstract 1
230000001575 pathological effect Effects 0.000 abstract 1
108010052768 tyrosyl-isoleucyl-glycyl-seryl-arginine Proteins 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Optics & Photonics (AREA)
Physics & Mathematics (AREA)
Pharmacology & Pharmacy (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Radiology & Medical Imaging (AREA)
Immunology (AREA)
Endocrinology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK93902846T 1992-01-03 1992-12-31 Farmaceutisk anvendelse af peptidmetalioner DK0629133T3 (da)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US07/816,477 US5460785A (en)	1989-08-09	1992-01-03	Direct labeling of antibodies and other protein with metal ions
US07/816,476 US5346687A (en)	1989-08-09	1992-01-03	Direct radiolabeling of antibody against stage specific embryonic antigen for diagnostic imaging
US07/840,077 US5443816A (en)	1990-08-08	1992-02-20	Peptide-metal ion pharmaceutical preparation and method
US07/998,820 US5738838A (en)	1992-02-20	1992-12-30	IKVAV peptide radiopharmaceutical applications
US07/998,910 US5556609A (en)	1992-02-20	1992-12-30	YIGSR peptide radiopharmaceutical applications
PCT/US1992/011334 WO1993012819A1 (en)	1992-01-03	1992-12-31	Protein- and peptide-metal ion pharmaceutical applications

Publications (1)

Publication Number	Publication Date
DK0629133T3 true DK0629133T3 (da)	2001-04-02

Family

ID=27542230

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93902846T DK0629133T3 (da)	1992-01-03	1992-12-31	Farmaceutisk anvendelse af peptidmetalioner

Country Status (8)

Country	Link
EP (1)	EP0629133B1 (da)
AT (1)	ATE197767T1 (da)
AU (1)	AU683833B2 (da)
CA (1)	CA2127284C (da)
DE (1)	DE69231586T2 (da)
DK (1)	DK0629133T3 (da)
ES (1)	ES2155447T3 (da)
WO (1)	WO1993012819A1 (da)

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US8038994B2 (en)	1996-05-15	2011-10-18	Quest Pharmatech Inc.	Combination therapy for treating disease
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US7060251B1 (en)	1997-09-08	2006-06-13	The General Hospital Corporation	Imaging agents for early detection and monitoring of cardiovascular plaque
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US7317104B2 (en)	2003-06-13	2008-01-08	Bristol-Myers Squibb Pharma Company	Chelants and macrocyclic metal complex radiopharmaceuticals thereof
US7319149B2 (en)	2003-06-13	2008-01-15	Bristol-Myers Squibb Pharma Company	Chelants and macrocyclic metal complex radiopharmaceuticals thereof
WO2005019247A2 (en) *	2003-08-15	2005-03-03	Board Of Regents, The University Of Texas System	Cyclic peptide and imaging compound compositions and uses for targeted imaging and therapy
EP1670520A4 (en)	2003-09-08	2009-07-22	Proportional Technologies Inc	MINIATURIZED 62ZN / 62CU GENERATOR FOR THE HIGHLY CONCENTRATED CLINICAL PROVISION OF A 62CU KIT FORMULATION FOR THE EASY MANAGEMENT OF RADIOACTIVELY MARKED CU-BIS (THIOSEMICARBAZONE) COMPOUNDS
US7763234B2 (en)	2004-03-04	2010-07-27	Ge Healthcare As	Pharmaceutical compounds
US7439012B2 (en)	2004-08-17	2008-10-21	Wake Forest University Health Sciences	Ambient stored blood plasma expanders containing keratose
US8920827B2 (en)	2005-10-21	2014-12-30	Wake Forest University Health Sciences	Keratin bioceramic compositions
US7892573B2 (en)	2006-02-10	2011-02-22	Wake Forest University Health Sciences	Nerve regeneration employing keratin biomaterials
EP1983927B1 (en)	2006-02-17	2014-11-05	Wake Forest University Health Sciences	Coatings and biomedical implants formed from keratin biomaterials
US8273702B2 (en)	2006-02-17	2012-09-25	Wake Forest University Health Sciences	Wound healing compositions containing keratin biomaterials
US9068162B2 (en)	2007-08-17	2015-06-30	Wake Forest University Health Sciences	Keratin biomaterials for cell culture and methods of use
FR2940103B1 (fr)	2008-12-19	2011-06-10	Oreal	Procede de coloration eclaircissante de matieres keratiniques mettant en oeuvre une emulsion comprenant un colorant et un agent alcalin et une composition oxydante
CN101822619B (zh)	2008-12-19	2014-03-26	莱雅公司	在无机碱存在下着色或色泽变淡的方法以及试剂盒
JP5711883B2 (ja)	2008-12-19	2015-05-07	ロレアル	脂肪物質に富む水性組成物の存在下で、淡色化し、あるいは淡色化直接染色し、あるいは酸化染色する方法、及びそのためのデバイス
FR2940077B1 (fr)	2008-12-19	2012-07-20	Oreal	Procede de coloration eclaircissante de matieres keratiniques mettant en oeuvre une composition anhydre colorante comprenant un agent alcalin et une composition oxydante.
US7935154B2 (en)	2008-12-19	2011-05-03	L'oreal S.A.	Process for lightening or lightening direct dyeing or oxidation dyeing in the presence of at least one organic amine and at least one inorganic base, and device therefor
BRPI0910081A2 (pt)	2008-12-19	2012-03-13	L'oreal	Processo de clareamento das fibras queratínicas humanas, processo de coloração das fibras queratínicas humanas e dispositivos com vários compartimentos
US7918902B2 (en)	2008-12-19	2011-04-05	L'oreal S.A.	Process for lightening or process for direct dyeing or oxidation dyeing of keratin fibers in the presence of at least one ammonium salt and device therefor
CN101780015A (zh)	2008-12-19	2010-07-21	莱雅公司	使用无水组合物和单乙醇胺/碱性氨基酸混合物染色或色泽变淡人角蛋白纤维的方法,和用于该方法的合适设备
FR2942704B1 (fr)	2009-03-04	2011-09-02	Oreal	Dispositif de distribution d'une composition tinctoriale pour les fibres keratiniques et procede associe.
FR2949971B1 (fr)	2009-09-17	2012-08-17	Oreal	Procede d'eclaircissement ou de coloration en presence d'une composition anhydre particuliere et dispositif
FR2951080B1 (fr)	2009-10-13	2012-01-20	Oreal	Composition comprenant un corps gras et un acide organophosphonique ou l'un de ses sels, procede de coloration ou d'eclaircissement la mettant en oeuvre et dispositifs
WO2011076647A2 (en)	2009-12-22	2011-06-30	L'oreal	Inverse emulsion for treating the hair comprising a particular fatty substance and an alkaline agent
FR2954160B1 (fr)	2009-12-22	2012-03-30	Oreal	Composition de coloration ou d'eclaircissement comprenant un corps gras et un polymere amphotere
FR2954127B1 (fr)	2009-12-22	2015-10-30	Oreal	Agent de coloration et/ou de decoloration des fibres keratiniques en deux parties, comprenant un corps gras et un agent sequestrant.
FR2954101B1 (fr)	2009-12-22	2012-05-11	Oreal	Agent de coloration et/ou de decoloration des fibres keratiniques en deux parties ou plus, comprenant une composition alcaline en emulsion inverse.
FR2954113B1 (fr)	2009-12-22	2013-03-08	Oreal	Agent de coloration et/ou de decoloration des fibres keratiniques en deux parties ou plus, sous forme d'emulsion.
WO2011076646A2 (en)	2009-12-22	2011-06-30	L'oreal	Agent for dyeing and/or bleaching keratin fibres, comprising an inverse emulsion comprising an oxidizing agent
FR2954121B1 (fr)	2009-12-22	2016-03-25	Oreal	Agent de coloration et/ou de decoloration des fibres keratiniques en deux parties, comprenant un corps gras particulier et une reductone.
FR2954161B1 (fr)	2009-12-23	2012-03-02	Oreal	Procede de coloration ou d'eclaircissement de fibres keratiniques en presence d'alcane(s) lineaire(s) volatil(s) et dispositif
EP2542564B1 (en)	2010-03-05	2018-05-09	Wake Forest University Health Sciences	Controlled delivery system
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FR2958161B1 (fr)	2010-04-02	2012-04-27	Oreal	Procede de traitement des cheveux mettant en oeuvre une emulsion directe comprenant un agent oxydant et une emulsion directe contenant un agent alcalin
FR2959127B1 (fr)	2010-04-22	2016-01-01	Oreal	Emulsion inverse pour le traitement des cheveux comprenant un solvant particulier
FR2960773B1 (fr)	2010-06-03	2015-12-11	Oreal	Procedes de traitement cosmetique utilisant un revetement a base d'un polymere polyamide-polyether
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NZ314680A (en) *	1989-05-09	2000-08-25	Ortho Pharma Corp	Treating localised infection or inflammation with a therapeutically conjugated chemotactic peptide
GB8914020D0 (en) *	1989-06-19	1989-08-09	Antisoma Ltd	Synthetic peptides for use in thrombus detection
AU638043B2 (en) *	1989-07-20	1993-06-17	Novartis Ag	Labeled polypeptide derivatives
WO1991001754A1 (en) *	1989-08-09	1991-02-21	Rhodes Buck A	Direct radiolabeling of antibodies and other proteins with technetium or rhenium
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CA2101942C (en) *	1991-02-08	2001-01-30	Richard T. Dean	Technetium-99m labeled polypeptides for imaging

1992
- 1992-12-31 ES ES93902846T patent/ES2155447T3/es not_active Expired - Lifetime
- 1992-12-31 DK DK93902846T patent/DK0629133T3/da active
- 1992-12-31 DE DE69231586T patent/DE69231586T2/de not_active Revoked
- 1992-12-31 AU AU34272/93A patent/AU683833B2/en not_active Ceased
- 1992-12-31 CA CA002127284A patent/CA2127284C/en not_active Expired - Fee Related
- 1992-12-31 EP EP93902846A patent/EP0629133B1/en not_active Revoked
- 1992-12-31 AT AT93902846T patent/ATE197767T1/de not_active IP Right Cessation
- 1992-12-31 WO PCT/US1992/011334 patent/WO1993012819A1/en not_active Ceased

Also Published As

Publication number	Publication date
AU3427293A (en)	1993-07-28
WO1993012819A1 (en)	1993-07-08
ES2155447T3 (es)	2001-05-16
CA2127284A1 (en)	1993-07-08
ATE197767T1 (de)	2000-12-15
DE69231586D1 (de)	2001-01-04
AU683833B2 (en)	1997-11-27
DE69231586T2 (de)	2001-07-19
CA2127284C (en)	2002-02-05
EP0629133A4 (en)	1995-02-01
EP0629133B1 (en)	2000-11-29
EP0629133A1 (en)	1994-12-21

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