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DK0669923T3 - Rapamycincarbonsyreestere som immunosuppresive midler - Google Patents

Rapamycincarbonsyreestere som immunosuppresive midler

Info

Publication number
DK0669923T3
DK0669923T3 DK93923281.5T DK93923281T DK0669923T3 DK 0669923 T3 DK0669923 T3 DK 0669923T3 DK 93923281 T DK93923281 T DK 93923281T DK 0669923 T3 DK0669923 T3 DK 0669923T3
Authority
DK
Denmark
Prior art keywords
rapamycin
immunosuppressants
carboxylic acid
acid esters
bromine
Prior art date
Application number
DK93923281.5T
Other languages
Danish (da)
English (en)
Inventor
David Cheng Hu
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Application granted granted Critical
Publication of DK0669923T3 publication Critical patent/DK0669923T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Grinding And Polishing Of Tertiary Curved Surfaces And Surfaces With Complex Shapes (AREA)
DK93923281.5T 1992-11-19 1993-10-06 Rapamycincarbonsyreestere som immunosuppresive midler DK0669923T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/979,072 US5260300A (en) 1992-11-19 1992-11-19 Rapamycin carbonate esters as immuno-suppressant agents

Publications (1)

Publication Number Publication Date
DK0669923T3 true DK0669923T3 (da) 1997-08-25

Family

ID=25526670

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93923281.5T DK0669923T3 (da) 1992-11-19 1993-10-06 Rapamycincarbonsyreestere som immunosuppresive midler

Country Status (15)

Country Link
US (1) US5260300A (fr)
EP (1) EP0669923B1 (fr)
JP (1) JPH08503210A (fr)
KR (1) KR950704330A (fr)
AT (1) ATE151769T1 (fr)
AU (1) AU5322094A (fr)
CA (1) CA2149669A1 (fr)
DE (1) DE69309954T2 (fr)
DK (1) DK0669923T3 (fr)
ES (1) ES2100572T3 (fr)
GR (1) GR3023801T3 (fr)
HK (1) HK109197A (fr)
HU (1) HUT73418A (fr)
SG (1) SG47595A1 (fr)
WO (1) WO1994011380A1 (fr)

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Also Published As

Publication number Publication date
DE69309954D1 (de) 1997-05-22
JPH08503210A (ja) 1996-04-09
CA2149669A1 (fr) 1994-05-26
ATE151769T1 (de) 1997-05-15
HU9501464D0 (en) 1995-07-28
EP0669923B1 (fr) 1997-04-16
EP0669923A1 (fr) 1995-09-06
HUT73418A (en) 1996-07-29
ES2100572T3 (es) 1997-06-16
GR3023801T3 (en) 1997-09-30
US5260300A (en) 1993-11-09
SG47595A1 (en) 1998-04-17
AU5322094A (en) 1994-06-08
KR950704330A (ko) 1995-11-17
HK109197A (en) 1997-08-22
WO1994011380A1 (fr) 1994-05-26
DE69309954T2 (de) 1997-07-24

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