PE20000245A1 - DERIVADOS DE PIRAZOL [1,5-b]PIRIDAZINA - Google Patents
DERIVADOS DE PIRAZOL [1,5-b]PIRIDAZINAInfo
- Publication number
- PE20000245A1 PE20000245A1 PE1999000079A PE00007999A PE20000245A1 PE 20000245 A1 PE20000245 A1 PE 20000245A1 PE 1999000079 A PE1999000079 A PE 1999000079A PE 00007999 A PE00007999 A PE 00007999A PE 20000245 A1 PE20000245 A1 PE 20000245A1
- Authority
- PE
- Peru
- Prior art keywords
- pyridazine
- phenyl
- alkyl
- derivatives
- pirazolo
- Prior art date
Links
- PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical compound C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 title abstract 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- -1 3-FLUORO-PHENYL Chemical class 0.000 abstract 1
- 229940093444 Cyclooxygenase 2 inhibitor Drugs 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical compound C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 abstract 1
- 206010037660 Pyrexia Diseases 0.000 abstract 1
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A DERIVADOS DE PIRAZOL [1,5-b]PIRIDAZINA DE FORMULA I, DONDE R° ES HALOGENO, ALQUILO C1-C6, ALCOXI C1-C6 OPCIONALMENTE SUSTITUIDO POR FLUOR; O(CH2)nNR4R5; R1 Y R2 SON H, ALQUILO C1-C6 OPCIONALMENTE SUSTITUIDO POR FLUOR; ALCOXI C1-C6, HIDROXIALQUILO C1-C6, ENTRE OTROS; R3 ES ALQUILO C1-C6, NH2; R4 Y R5 SON H, ALQUILO C1-C6, O JUNTO CON EL N FORMAN UN ANILLO DE 4-8 MIEMBROS; n ES 1-4. SON COMPUESTOS PREFERIDOS 2-(4-ETOXI-FENIL)-3-(4-METANSULFONIL-FENIL)-PIRAZOLO[1,5-b]PIRIDAZINA, 6-DIFLUOROMETOXI-2-(3-FLUORO-FENIL)-3-(4-METANSULFONIL-FENIL)-PIRAZOLO[1,5-b]-PIRIDAZINA. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION. EL COMPUESTO I ES INHIBIDOR DE CICLOOXIGENASA-2 Y PUEDE SER UTIL EN EL TRATAMIENTO DEL DOLOR, FIEBRE, INFLAMACION
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PE1999000079A PE20000245A1 (es) | 1999-02-02 | 1999-02-02 | DERIVADOS DE PIRAZOL [1,5-b]PIRIDAZINA |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PE1999000079A PE20000245A1 (es) | 1999-02-02 | 1999-02-02 | DERIVADOS DE PIRAZOL [1,5-b]PIRIDAZINA |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20000245A1 true PE20000245A1 (es) | 2000-03-29 |
Family
ID=46799410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999000079A PE20000245A1 (es) | 1999-02-02 | 1999-02-02 | DERIVADOS DE PIRAZOL [1,5-b]PIRIDAZINA |
Country Status (1)
| Country | Link |
|---|---|
| PE (1) | PE20000245A1 (es) |
-
1999
- 1999-02-02 PE PE1999000079A patent/PE20000245A1/es not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |