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DK0533410T3 - Fremgangsmåder til administration af dipalmitoylphosphatidylcholindispersioner - Google Patents

Fremgangsmåder til administration af dipalmitoylphosphatidylcholindispersioner

Info

Publication number
DK0533410T3
DK0533410T3 DK92308285.3T DK92308285T DK0533410T3 DK 0533410 T3 DK0533410 T3 DK 0533410T3 DK 92308285 T DK92308285 T DK 92308285T DK 0533410 T3 DK0533410 T3 DK 0533410T3
Authority
DK
Denmark
Prior art keywords
dispersion
administering
dipalmitoylphosphatidylcholine
lungs
patient
Prior art date
Application number
DK92308285.3T
Other languages
English (en)
Inventor
Craig William Davis
Rodney Gary Snyder
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of DK0533410T3 publication Critical patent/DK0533410T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0082Lung surfactant, artificial mucus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK92308285.3T 1991-09-19 1992-09-11 Fremgangsmåder til administration af dipalmitoylphosphatidylcholindispersioner DK0533410T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919120005A GB9120005D0 (en) 1991-09-19 1991-09-19 Method of administering phospholipid dispersions

Publications (1)

Publication Number Publication Date
DK0533410T3 true DK0533410T3 (da) 1997-09-08

Family

ID=10701652

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92308285.3T DK0533410T3 (da) 1991-09-19 1992-09-11 Fremgangsmåder til administration af dipalmitoylphosphatidylcholindispersioner

Country Status (19)

Country Link
US (1) US5299566A (da)
EP (1) EP0533410B1 (da)
JP (1) JPH06505505A (da)
KR (1) KR930702006A (da)
AT (1) ATE150312T1 (da)
AU (1) AU2554292A (da)
CA (1) CA2096537C (da)
CZ (1) CZ93593A3 (da)
DE (1) DE69218329T2 (da)
DK (1) DK0533410T3 (da)
ES (1) ES2100296T3 (da)
FI (1) FI932254L (da)
GB (1) GB9120005D0 (da)
GR (1) GR3023534T3 (da)
HU (1) HUT64697A (da)
IL (1) IL103216A0 (da)
SK (1) SK51093A3 (da)
WO (1) WO1993005787A1 (da)
ZA (1) ZA927178B (da)

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US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
DE69811407T2 (de) 1997-12-24 2003-11-20 Britannia Pharmaceuticals Ltd., Redhill Verwendung eines oberflächenaktiven mittels zur herstellung eines arzneimittels zur behandlung von erkrankungen des mittelohrs
US5883084A (en) * 1998-06-08 1999-03-16 Clarion Pharmaceuticals Inc. Treatment of respiratory diseases utilizing α-tocopheryl-phosphocholine
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6676930B2 (en) 1999-11-28 2004-01-13 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
US6156294A (en) 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
DE19957898A1 (de) * 1999-12-01 2001-06-07 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US7273847B2 (en) * 2000-06-30 2007-09-25 Mccormack Jr Francis X Peptides with antioxidant and antimicrobial properties
US6770619B2 (en) * 2000-09-01 2004-08-03 Marcus Larsson Lung surfactant compositions with dynamic swelling behavior
RU2189820C1 (ru) * 2001-05-03 2002-09-27 Институт медицинских проблем Севера СО РАМН Способ лечения бронхиальной астмы
WO2003053411A1 (en) 2001-12-19 2003-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
US20040055595A1 (en) * 2002-09-19 2004-03-25 Noymer Peter D. Aerosol drug delivery system employing formulation pre-heating
JP2007537833A (ja) * 2004-05-20 2007-12-27 ディスカバリー ラボラトリーズ,インコーポレイテッド 非侵襲的な肺吸入のための方法、システム、及び装置
US8337815B2 (en) * 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
US8028697B2 (en) 2005-04-28 2011-10-04 Trudell Medical International Ventilator circuit and method for the use thereof
US20070031342A1 (en) * 2005-06-22 2007-02-08 Nektar Therapeutics Sustained release microparticles for pulmonary delivery
EP2086617A4 (en) * 2006-10-26 2013-11-20 Next Breath Llc INHALATION SYSTEM BASED ON PHOSPHOLIPIDS
DE102007025898A1 (de) * 2007-06-01 2008-12-04 Matthias W. Dr. Amrein Behandlung von Surfactanten
EP2265309B1 (en) * 2008-03-17 2015-12-16 Discovery Laboratories, Inc. Ventilation circuit adaptor and proximal aerosol delivery system
CA2683353C (en) 2008-10-22 2015-12-15 Trudell Medical International Modular aerosol delivery system
MX2013001936A (es) 2010-08-23 2013-03-08 Takeda Gmbh Particulas humidificadas que comprenden una sustancia terapeuticamente activa.
AU2016225111B2 (en) 2015-02-27 2021-12-09 Board Of Regents, The University Of Texas System Polypeptide therapeutics and uses thereof
AU2019339260B2 (en) 2018-09-10 2025-06-26 Rein Therapeutics, Inc. Modified peptide fragments of Cav-1 protein and the use thereof in the treatment of fibrosis
WO2020185826A1 (en) 2019-03-11 2020-09-17 Lung Therapeutics, Inc. Compositions and methods for protecting type 2 alveolar epithelial cells (aec2)

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US5038769A (en) * 1983-06-29 1991-08-13 Krauser Robert S Method and apparatus for treating ailments
US4912038A (en) * 1984-12-11 1990-03-27 California Biotechnology Inc. Recombinant DNA sequence encoding alveolar surfactant protein
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US5057502A (en) * 1987-06-02 1991-10-15 Walsh William E Composition and topical and systemic treatments of conditions caused by heavy, oily or greasy secretions
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JP3171445B2 (ja) * 1990-10-17 2001-05-28 ザ リポソーム カンパニー,インコーポレイテッド 合成肺表面活性剤

Also Published As

Publication number Publication date
SK51093A3 (en) 1993-10-06
US5299566A (en) 1994-04-05
GR3023534T3 (en) 1997-08-29
ATE150312T1 (de) 1997-04-15
FI932254A7 (fi) 1993-07-02
EP0533410B1 (en) 1997-03-19
WO1993005787A1 (en) 1993-04-01
KR930702006A (ko) 1993-09-08
HU9301430D0 (en) 1993-09-28
DE69218329D1 (de) 1997-04-24
DE69218329T2 (de) 1997-07-03
FI932254L (fi) 1993-07-02
GB9120005D0 (en) 1991-11-06
CA2096537A1 (en) 1993-03-20
ES2100296T3 (es) 1997-06-16
CA2096537C (en) 2003-12-30
AU2554292A (en) 1993-04-27
ZA927178B (en) 1994-03-18
EP0533410A1 (en) 1993-03-24
FI932254A0 (fi) 1993-05-18
CZ93593A3 (en) 1994-02-16
HUT64697A (en) 1994-02-28
JPH06505505A (ja) 1994-06-23
IL103216A0 (en) 1993-02-21

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