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WO1996020702B1 - The use of 2,3-alkylcarbonyloxybenzoic acid in treating adult respiratory distress syndrome - Google Patents

The use of 2,3-alkylcarbonyloxybenzoic acid in treating adult respiratory distress syndrome

Info

Publication number
WO1996020702B1
WO1996020702B1 PCT/US1995/016892 US9516892W WO9620702B1 WO 1996020702 B1 WO1996020702 B1 WO 1996020702B1 US 9516892 W US9516892 W US 9516892W WO 9620702 B1 WO9620702 B1 WO 9620702B1
Authority
WO
WIPO (PCT)
Prior art keywords
respiratory distress
distress syndrome
adult respiratory
treating adult
ards
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1995/016892
Other languages
French (fr)
Other versions
WO1996020702A1 (en
Filing date
Publication date
Priority claimed from US08/366,885 external-priority patent/US5504111A/en
Application filed filed Critical
Priority to EP95944240A priority Critical patent/EP0801563B1/en
Priority to JP8521126A priority patent/JPH10511953A/en
Priority to AT95944240T priority patent/ATE235238T1/en
Priority to DE69530120T priority patent/DE69530120T2/en
Priority to AU46090/96A priority patent/AU4609096A/en
Publication of WO1996020702A1 publication Critical patent/WO1996020702A1/en
Publication of WO1996020702B1 publication Critical patent/WO1996020702B1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Abstract

This invention relates to methods for treating Adult Respiratory Distress Syndrome (ARDS) which involves the administration of 2,3-alkylcarbonyloxybenzoic acid and salts thereof wherein the alkyl group has 2-18 carbon atoms.

Claims

- -AMENDED CLAIMS[received by the International Bureau on 2 July 1996 (02.07.96); new claims 3-6 added; remaining claims unchanged (1 page)]
1. A method for treating Adult Respiratory Distress Syndrome (ARDS) comprising administering to a subject in need of ARDS therapy an effective therapeutic amount of 2,3-alkylcarbonyloxybenzoic acid and salts thereof wherein the alkylcarbonyl group has 12-18 carbon atoms.
2. The method of Claim 1, wherein ibuprofen is administered in combination with 2,3-alkylcarbonyloxybenzoic acid.
3. A pharmaceutical composition for treating Adult Respiratory Distress Syndrome (ARDS) comprising 2,3-alkylcarbonyloxybenzoic acid or salts thereof wherein the alkylcarbonyl group has 2-18 carbon atoms.
4. The pharmaceutical composition of Claim 3, further comprising ibuprofen.
5. A pharmaceutical composition for treating Adult Respiratory Distress Syndrome (ARDS) comprising an effective therapeutic amount of 2,3- alkylcarbonyloxybenzoic acid or salts thereof and ibuprofen.
6. The pharmaceutical composition of Claim 5, wherein the alkylcarboxyl group has 2-18 carbon atoms.
PCT/US1995/016892 1994-12-30 1995-12-21 The use of 2,3-alkylcarbonyloxybenzoic acid in treating adult respiratory distress syndrome Ceased WO1996020702A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP95944240A EP0801563B1 (en) 1994-12-30 1995-12-21 The use of 2,3-alkylcarbonyloxybenzoic acid in treating adult respiratory distress syndrome
JP8521126A JPH10511953A (en) 1994-12-30 1995-12-21 Utilization of 2,3-alkylcarboxybenzoic acid in adult respiratory distress syndrome
AT95944240T ATE235238T1 (en) 1994-12-30 1995-12-21 USE OF 2,3-ALKYLCAEBONYLOXYBENZOIC ACID FOR THE TREATMENT OF RESPIRATORY UNAWARENESS SYDROME IN ADULTS
DE69530120T DE69530120T2 (en) 1994-12-30 1995-12-21 USE OF 2,3-ALKYLCAEBONYLOXYBENZOIC ACID FOR THE TREATMENT OF BREATHING TEMPERATURE IN ADDITIVES
AU46090/96A AU4609096A (en) 1994-12-30 1995-12-21 The use of 2,3-alkylcarbonyloxybenzoic acid in treating adult respiratory distress syndrome

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/366,885 US5504111A (en) 1994-12-30 1994-12-30 Use of 2,3 alkylcarbonyloxybenzoic acid in treating adult respiratory distress syndrome
US08/366,885 1994-12-30

Publications (2)

Publication Number Publication Date
WO1996020702A1 WO1996020702A1 (en) 1996-07-11
WO1996020702B1 true WO1996020702B1 (en) 1996-08-22

Family

ID=23444992

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/016892 Ceased WO1996020702A1 (en) 1994-12-30 1995-12-21 The use of 2,3-alkylcarbonyloxybenzoic acid in treating adult respiratory distress syndrome

Country Status (7)

Country Link
US (1) US5504111A (en)
EP (2) EP0801563B1 (en)
JP (1) JPH10511953A (en)
AT (2) ATE337789T1 (en)
AU (1) AU4609096A (en)
DE (2) DE69530120T2 (en)
WO (1) WO1996020702A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955496A (en) * 1996-08-13 1999-09-21 The Regents Of The University Of California Dihydroxy-oxy-eicosadienoates
US6174695B1 (en) 1997-08-12 2001-01-16 The Regents Of The University Of California Epoxide hydrolase inhibitor methods
WO2004032825A2 (en) * 2001-11-02 2004-04-22 Advanced Life Sciences, Inc. Use of 2,3 alkylcarbonyloxybenzoic acids in the treatment of anthrax
WO2004010989A1 (en) * 2002-07-25 2004-02-05 Advances Life Sciences, Inc. Use of 2,3 alkylcarbonyloxybenzoic acids, derivatives and analogues therefrom in the treatment of tissue and cellular dysfunction damage and injury in mammals

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3270988D1 (en) * 1981-07-20 1986-06-12 Upjohn Co Use of ibuprofen or flurbiprofen for the manufacture of a medicament for treating respiratory disorders
US4443476A (en) * 1981-07-20 1984-04-17 The Upjohn Company Treatment of adult respiratory distress syndrome
US4447451A (en) * 1981-07-20 1984-05-08 The Upjohn Manufacturing Company M Treatment of adult respiratory distress syndrome
US4686100A (en) * 1985-04-02 1987-08-11 The Board Of Trustees Of The Leland Stanford Junior University Method for the treatment of adult respiratory distress syndrome
US4703040A (en) * 1985-04-03 1987-10-27 Markov Angel K Treatment of adult respiratory distress syndrome (ARDS) using fructose diphosphate (FDP)
US5198420A (en) * 1989-10-02 1993-03-30 The General Hospital Corporation Use of mullerian inhibiting substance and its agonists and antagonists in the treatment of respiratory distress syndrome
IE911697A1 (en) * 1990-05-24 1991-12-04 Zeneca Ltd Therapeutic agent
JP2925391B2 (en) * 1992-01-09 1999-07-28 サントリー株式会社 Pharmaceutical composition for treating ARDS
US5389522A (en) * 1993-03-19 1995-02-14 Repine; John E. Serum antioxidants as predictors of the adult respiratory distress syndrome in septic patients

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