DK0531415T3 - Fremgangsmåde til behandling af alkoholisme med balmefen - Google Patents
Fremgangsmåde til behandling af alkoholisme med balmefenInfo
- Publication number
- DK0531415T3 DK0531415T3 DK91910595.7T DK91910595T DK0531415T3 DK 0531415 T3 DK0531415 T3 DK 0531415T3 DK 91910595 T DK91910595 T DK 91910595T DK 0531415 T3 DK0531415 T3 DK 0531415T3
- Authority
- DK
- Denmark
- Prior art keywords
- balmfef
- treating alcoholism
- alcoholism
- treating
- alcoholics
- Prior art date
Links
- 208000007848 Alcoholism Diseases 0.000 title abstract 2
- 201000007930 alcohol dependence Diseases 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- WJBLNOPPDWQMCH-MBPVOVBZSA-N Nalmefene Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=C)O)CC1)O)CC1CC1 WJBLNOPPDWQMCH-MBPVOVBZSA-N 0.000 abstract 1
- 235000013334 alcoholic beverage Nutrition 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229960005297 nalmefene Drugs 0.000 abstract 1
- 239000003401 opiate antagonist Substances 0.000 abstract 1
- 230000002787 reinforcement Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/532,424 US5086058A (en) | 1990-06-04 | 1990-06-04 | Method for treating alcoholism with nalmefene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0531415T3 true DK0531415T3 (da) | 1996-12-09 |
Family
ID=24121726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91910595.7T DK0531415T3 (da) | 1990-06-04 | 1991-05-10 | Fremgangsmåde til behandling af alkoholisme med balmefen |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5086058A (da) |
| EP (1) | EP0531415B1 (da) |
| JP (1) | JP3059213B2 (da) |
| AT (1) | ATE145329T1 (da) |
| AU (1) | AU642748B2 (da) |
| CA (1) | CA2084519C (da) |
| DE (1) | DE69123247T2 (da) |
| DK (1) | DK0531415T3 (da) |
| ES (1) | ES2097209T3 (da) |
| FI (1) | FI925513A0 (da) |
| GR (1) | GR3022289T3 (da) |
| HU (1) | HU210637B (da) |
| IE (1) | IE77333B1 (da) |
| LT (1) | LT3893B (da) |
| LV (1) | LV10190B (da) |
| NZ (1) | NZ238391A (da) |
| RU (1) | RU2090190C1 (da) |
| WO (1) | WO1991018605A1 (da) |
| ZA (1) | ZA914185B (da) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4882335A (en) * | 1988-06-13 | 1989-11-21 | Alko Limited | Method for treating alcohol-drinking response |
| US6271239B1 (en) * | 1992-04-13 | 2001-08-07 | Regents Of The University Of Minnesota | Delta opioid receptor-selective benzylidene-substituted morphinans |
| US5352680A (en) * | 1992-07-15 | 1994-10-04 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists to block opioid agonist tolerance and dependence |
| US5580876A (en) * | 1992-09-21 | 1996-12-03 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| US6096756A (en) | 1992-09-21 | 2000-08-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| USRE36547E (en) * | 1992-09-21 | 2000-02-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opioid agonists |
| US5298622A (en) * | 1993-05-12 | 1994-03-29 | Regents Of The University Of Minnesota | Spiroindane opiate analogs |
| US5457208A (en) | 1993-06-21 | 1995-10-10 | Regents Of The University Of Minnesota | Kappa opioid receptor antagonists |
| US5587381A (en) * | 1995-03-27 | 1996-12-24 | Sinclair; John D. | Method for terminating methadone maintenance through extinction of the opiate-taking responses |
| WO1997018781A1 (en) * | 1995-11-20 | 1997-05-29 | University Of Miami | Method of treating nicotine dependence |
| US5878750A (en) * | 1996-11-14 | 1999-03-09 | Clemens; Anton H. | Method of treating the syndrome of coronary heart disease risk factors in humans |
| US5780479A (en) * | 1997-04-04 | 1998-07-14 | Regents Of The University Of Minnesota | Use of opioid antagonists to treat impulse-control disorders |
| US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
| CN1204890C (zh) | 1997-12-22 | 2005-06-08 | 欧罗赛铁克股份有限公司 | 防止阿片样物质滥用的方法 |
| PT1685839E (pt) | 1997-12-22 | 2013-07-08 | Euro Celtique Sa | Forma de dosagem farmacêutica por via oral compreendendo uma combinação de um agonista opióide e de um antagonista opióide |
| EP1248800A2 (en) * | 1999-11-30 | 2002-10-16 | Corixa Corporation | Compositions and methods for therapy and diagnosis of breast cancer |
| US6716449B2 (en) | 2000-02-08 | 2004-04-06 | Euro-Celtique S.A. | Controlled-release compositions containing opioid agonist and antagonist |
| WO2001058447A1 (en) | 2000-02-08 | 2001-08-16 | Euro-Celtique, S.A. | Controlled-release compositions containing opioid agonist and antagonist |
| US20040024004A1 (en) * | 2001-05-04 | 2004-02-05 | Sherman Barry M. | Novel compositions and methods for enhancing potency or reducing adverse side effects of opioid agonists |
| RU2227004C2 (ru) * | 2000-06-16 | 2004-04-20 | Писаренко Фаля Юрьевич | Способ лечения наркологической зависимости |
| US6846831B2 (en) | 2000-08-15 | 2005-01-25 | Cpd, Llc | Method of treating the syndrome of lipodystrophy |
| US6262062B1 (en) * | 2000-08-15 | 2001-07-17 | Cpd, Llc | Method of treating the syndrome of coronary heart disease risk factors in humans |
| US6528520B2 (en) * | 2000-08-15 | 2003-03-04 | Cpd, Llc | Method of treating the syndrome of coronary heart disease risk factors in humans |
| DE60238756D1 (de) | 2001-05-11 | 2011-02-10 | Endo Pharmaceuticals Inc | Opioid enthaltende arzneiform gegen missbrauch |
| CN1273075C (zh) * | 2001-07-13 | 2006-09-06 | 爱科来株式会社 | 分析用具、具备分析用具的浓度测定装置用的穿刺元件一体化安装体及体液采取用具 |
| AU2002316738B2 (en) * | 2001-07-18 | 2009-01-08 | Euro-Celtique S.A. | Pharmaceutical combinations of oxycodone and naloxone |
| US20030044458A1 (en) * | 2001-08-06 | 2003-03-06 | Curtis Wright | Oral dosage form comprising a therapeutic agent and an adverse-effect agent |
| US20030157168A1 (en) * | 2001-08-06 | 2003-08-21 | Christopher Breder | Sequestered antagonist formulations |
| ES2326794T3 (es) | 2001-08-06 | 2009-10-20 | Euro-Celtique S.A. | Formulaciones de agonistas opioides con antagonista liberable y secuestrado. |
| WO2003015783A1 (en) * | 2001-08-14 | 2003-02-27 | Biotie Therapies Corporation | Method of treating alcoholism or alcohol abuse |
| RU2215527C2 (ru) * | 2001-09-28 | 2003-11-10 | Областная наркологическая больница | Способ купирования алкогольного абстинентного синдрома, алкогольного делирия, острого алкогольного галлюциноза |
| RU2200556C1 (ru) * | 2001-12-05 | 2003-03-20 | Северцев Владимир Алексеевич | Лекарственная форма налтрексона |
| PT2425824T (pt) | 2002-04-05 | 2017-08-23 | Mundipharma Farmacêutica Lda | Preparação farmacêutica contendo oxicodona e naloxona |
| US7923454B2 (en) * | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7501433B2 (en) * | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7736665B2 (en) * | 2002-05-31 | 2010-06-15 | Titan Pharmaceuticals, Inc. | Implantable polymeric device for sustained release of buprenorphine |
| US7815934B2 (en) * | 2002-09-20 | 2010-10-19 | Alpharma Pharmaceuticals, Llc | Sequestering subunit and related compositions and methods |
| SI1610791T1 (sl) * | 2003-03-31 | 2011-05-31 | Titan Pharmaceuticals Inc | Implantibilna polimerna naprava za zadržano sproščanje dopaminskega agonista |
| US20040202717A1 (en) | 2003-04-08 | 2004-10-14 | Mehta Atul M. | Abuse-resistant oral dosage forms and method of use thereof |
| EP1613324A2 (en) * | 2003-04-14 | 2006-01-11 | Pain Therapeutics, Inc. | Methods for the treatment of pain comprising opioid antagonists |
| MY135852A (en) | 2003-04-21 | 2008-07-31 | Euro Celtique Sa | Pharmaceutical products |
| US8017622B2 (en) * | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US20060009478A1 (en) * | 2003-10-15 | 2006-01-12 | Nadav Friedmann | Methods for the treatment of back pain |
| EP1604666A1 (en) * | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD) |
| EP1702558A1 (en) * | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Method and device for the assessment of bowel function |
| PT2484346T (pt) | 2006-06-19 | 2017-04-26 | Alpharma Pharmaceuticals Llc | Composições farmacêuticas |
| BRPI0718420A2 (pt) | 2006-10-20 | 2013-11-12 | Cpd Llc | Método de restabelecimento do efeito da incretina |
| US8623418B2 (en) * | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
| WO2009088673A2 (en) * | 2007-12-17 | 2009-07-16 | Alpharma Pharmaceuticals, Llc | Pharmaceutical composition |
| US20100151014A1 (en) * | 2008-12-16 | 2010-06-17 | Alpharma Pharmaceuticals, Llc | Pharmaceutical composition |
| PL2307420T3 (pl) * | 2008-04-24 | 2012-04-30 | Janssen Pharmaceutica Nv | Proleki diestrowe nalmefenu |
| ME01319B (me) * | 2008-04-24 | 2013-12-20 | Janssen Pharmaceutica Nv | Prolijekovi nalmefena |
| MX2011000155A (es) * | 2008-07-07 | 2011-03-01 | Euro Celtique Sa | Uso de antagonistas opioides para el tratamiento de retencion urinaria. |
| RU2393864C1 (ru) * | 2008-12-29 | 2010-07-10 | Руслан Дмитриевич Илюк | Средство для профилактики и лечения алкоголизма и опиоидной наркомании |
| ME03298B (me) | 2009-03-10 | 2019-07-20 | Euro Celtique Sa | Farmaceutske kombinacije sa trenutnim oslobađanjem које obuhvataju oksikodon i nalokson |
| US20140005216A1 (en) | 2012-06-27 | 2014-01-02 | H. Lundbeck A/S | Nalmefene for reduction of alcohol consumption in specific target populations |
| WO2014170353A1 (en) * | 2013-04-17 | 2014-10-23 | H. Lundbeck A/S | Nalmefene for treatment of patients with sleep disorder |
| CN105517551A (zh) | 2013-07-23 | 2016-04-20 | 欧洲凯尔特公司 | 用于在患有疼痛和导致肠生态失调和/或提高肠细菌移位风险之疾病的患者中治疗疼痛的羟考酮与纳洛酮的组合 |
| JP6797691B2 (ja) * | 2014-04-22 | 2020-12-09 | 大塚製薬株式会社 | ブレクスピプラゾールとナルメフェンの組み合わせ剤及び物質関連障害を治療するためのその用途 |
| EP3215154B1 (en) | 2014-11-07 | 2020-01-29 | Regents of the University of Minnesota | Salts and compositions useful for treating disease |
| BR112018071705A2 (pt) * | 2016-04-22 | 2019-02-19 | Taiwanj Pharmaceuticals Co., Ltd. | método de profilaxia ou tratamento de nafld, nash ou ash, uso de um composto de fórmula (i), e composto de fórmula (i) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4882335A (en) * | 1988-06-13 | 1989-11-21 | Alko Limited | Method for treating alcohol-drinking response |
| US4857533A (en) * | 1988-12-15 | 1989-08-15 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for autoimmune diseases |
| US4863928A (en) * | 1989-01-04 | 1989-09-05 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for arthritic and inflammatory diseases |
| US5096715A (en) * | 1989-11-20 | 1992-03-17 | Alko Ltd. | Method and means for treating alcoholism by extinguishing the alcohol-drinking response using a transdermally administered opiate antagonist |
-
1990
- 1990-06-04 US US07/532,424 patent/US5086058A/en not_active Expired - Lifetime
-
1991
- 1991-05-10 RU RU9192016403A patent/RU2090190C1/ru active
- 1991-05-10 ES ES91910595T patent/ES2097209T3/es not_active Expired - Lifetime
- 1991-05-10 HU HU9203835A patent/HU210637B/hu unknown
- 1991-05-10 AT AT91910595T patent/ATE145329T1/de not_active IP Right Cessation
- 1991-05-10 DK DK91910595.7T patent/DK0531415T3/da active
- 1991-05-10 EP EP91910595A patent/EP0531415B1/en not_active Expired - Lifetime
- 1991-05-10 FI FI925513A patent/FI925513A0/fi unknown
- 1991-05-10 CA CA002084519A patent/CA2084519C/en not_active Expired - Lifetime
- 1991-05-10 DE DE69123247T patent/DE69123247T2/de not_active Expired - Lifetime
- 1991-05-10 AU AU79740/91A patent/AU642748B2/en not_active Expired
- 1991-05-10 WO PCT/US1991/003241 patent/WO1991018605A1/en not_active Ceased
- 1991-05-10 JP JP3509984A patent/JP3059213B2/ja not_active Expired - Lifetime
- 1991-06-03 ZA ZA914185A patent/ZA914185B/xx unknown
- 1991-06-04 NZ NZ238391A patent/NZ238391A/en not_active IP Right Cessation
- 1991-06-04 IE IE188891A patent/IE77333B1/en not_active IP Right Cessation
-
1993
- 1993-08-31 LV LVP-93-1052A patent/LV10190B/en unknown
- 1993-11-25 LT LTIP1486A patent/LT3893B/lt not_active IP Right Cessation
-
1997
- 1997-01-16 GR GR960403307T patent/GR3022289T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI925513A7 (fi) | 1992-12-04 |
| JPH06506665A (ja) | 1994-07-28 |
| ATE145329T1 (de) | 1996-12-15 |
| CA2084519C (en) | 1999-02-09 |
| AU7974091A (en) | 1991-12-31 |
| AU642748B2 (en) | 1993-10-28 |
| IE77333B1 (en) | 1997-12-03 |
| CA2084519A1 (en) | 1991-12-05 |
| LTIP1486A (en) | 1995-09-25 |
| ZA914185B (en) | 1992-07-29 |
| US5086058A (en) | 1992-02-04 |
| FI925513L (fi) | 1992-12-04 |
| RU2090190C1 (ru) | 1997-09-20 |
| EP0531415B1 (en) | 1996-11-20 |
| WO1991018605A1 (en) | 1991-12-12 |
| FI925513A0 (fi) | 1992-12-04 |
| HU9203835D0 (en) | 1993-03-29 |
| JP3059213B2 (ja) | 2000-07-04 |
| EP0531415A1 (en) | 1993-03-17 |
| LV10190B (en) | 1995-06-20 |
| DE69123247D1 (de) | 1997-01-02 |
| DE69123247T2 (de) | 1998-01-15 |
| LT3893B (en) | 1996-04-25 |
| HU210637B (en) | 1995-06-28 |
| NZ238391A (en) | 1997-06-24 |
| ES2097209T3 (es) | 1997-04-01 |
| HUT65523A (en) | 1994-06-28 |
| LV10190A (lv) | 1994-10-20 |
| IE911888A1 (en) | 1991-12-04 |
| GR3022289T3 (en) | 1997-04-30 |
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