DK0508995T3 - Muscarinreceptor-antagonister - Google Patents
Muscarinreceptor-antagonisterInfo
- Publication number
- DK0508995T3 DK0508995T3 DK91900776.5T DK91900776T DK0508995T3 DK 0508995 T3 DK0508995 T3 DK 0508995T3 DK 91900776 T DK91900776 T DK 91900776T DK 0508995 T3 DK0508995 T3 DK 0508995T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- independently
- muscarinic receptor
- receptor antagonists
- so2nh2
- Prior art date
Links
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 title abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 8
- 229910006074 SO2NH2 Inorganic materials 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- -1 -(CH2)qOH Chemical group 0.000 abstract 1
- 125000001637 1-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C(*)=C([H])C([H])=C([H])C2=C1[H] 0.000 abstract 1
- 125000001622 2-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C([H])=C(*)C([H])=C([H])C2=C1[H] 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
- 239000003149 muscarinic antagonist Substances 0.000 abstract 1
- 125000003373 pyrazinyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909000302A GB9000302D0 (en) | 1990-01-06 | 1990-01-06 | Muscarinic receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0508995T3 true DK0508995T3 (da) | 1994-03-21 |
Family
ID=10668923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91900776.5T DK0508995T3 (da) | 1990-01-06 | 1990-11-28 | Muscarinreceptor-antagonister |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0508995B1 (da) |
| JP (1) | JPH0692376B2 (da) |
| AT (1) | ATE101599T1 (da) |
| CA (1) | CA2069931C (da) |
| DE (1) | DE69006745T2 (da) |
| DK (1) | DK0508995T3 (da) |
| ES (1) | ES2062755T3 (da) |
| FI (1) | FI922346A7 (da) |
| GB (1) | GB9000302D0 (da) |
| IE (1) | IE63685B1 (da) |
| PT (1) | PT96420B (da) |
| WO (1) | WO1991010654A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4117123A1 (de) * | 1991-05-25 | 1992-11-26 | Dresden Arzneimittel | Neue 5-aminoacyl-5,10-dihydro-11h-dibenzo/b,e//1,4/-diazepin-11-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| WO1994022861A1 (en) * | 1993-04-05 | 1994-10-13 | Pharmaceutical Discovery Corporation | PYRIDO[2,3-b][1,4]BENZODIAZEPINONES AS M2 RECEPTOR LIGAND FOR THE TREATMENT OF NEUROLOGICAL DISORDERS |
| AU3754495A (en) * | 1994-10-31 | 1996-05-23 | Yamanouchi Pharmaceutical Co., Ltd. | Novel benzodiazepinone derivative and medicinal composition thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4210648A (en) * | 1977-05-31 | 1980-07-01 | Boehringer Ingelheim Gmbh | II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof |
| DE3820345A1 (de) * | 1988-06-15 | 1989-12-21 | Thomae Gmbh Dr K | Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1990
- 1990-01-06 GB GB909000302A patent/GB9000302D0/en active Pending
- 1990-11-28 AT AT91900776T patent/ATE101599T1/de not_active IP Right Cessation
- 1990-11-28 JP JP3501208A patent/JPH0692376B2/ja not_active Expired - Lifetime
- 1990-11-28 DK DK91900776.5T patent/DK0508995T3/da active
- 1990-11-28 WO PCT/EP1990/002044 patent/WO1991010654A1/en not_active Ceased
- 1990-11-28 CA CA002069931A patent/CA2069931C/en not_active Expired - Fee Related
- 1990-11-28 DE DE69006745T patent/DE69006745T2/de not_active Expired - Fee Related
- 1990-11-28 ES ES91900776T patent/ES2062755T3/es not_active Expired - Lifetime
- 1990-11-28 EP EP91900776A patent/EP0508995B1/en not_active Expired - Lifetime
-
1991
- 1991-01-04 PT PT96420A patent/PT96420B/pt not_active IP Right Cessation
- 1991-01-04 IE IE1791A patent/IE63685B1/en not_active IP Right Cessation
-
1992
- 1992-05-22 FI FI922346A patent/FI922346A7/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69006745T2 (de) | 1994-06-01 |
| CA2069931C (en) | 1997-08-26 |
| DE69006745D1 (de) | 1994-03-24 |
| FI922346A0 (fi) | 1992-05-22 |
| IE910017A1 (en) | 1991-07-17 |
| ATE101599T1 (de) | 1994-03-15 |
| CA2069931A1 (en) | 1991-07-07 |
| JPH05501711A (ja) | 1993-04-02 |
| WO1991010654A1 (en) | 1991-07-25 |
| PT96420B (pt) | 1997-05-28 |
| EP0508995B1 (en) | 1994-02-16 |
| GB9000302D0 (en) | 1990-03-07 |
| PT96420A (pt) | 1991-10-15 |
| EP0508995A1 (en) | 1992-10-21 |
| IE63685B1 (en) | 1995-05-31 |
| FI922346A7 (fi) | 1992-05-22 |
| ES2062755T3 (es) | 1994-12-16 |
| JPH0692376B2 (ja) | 1994-11-16 |
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