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DK0594576T3 - Immunoafprøvninger for og monoklonale antistoffer over for prothrombin-aktivering-peptider og deres nedbrydningsprodukter - Google Patents

Immunoafprøvninger for og monoklonale antistoffer over for prothrombin-aktivering-peptider og deres nedbrydningsprodukter

Info

Publication number
DK0594576T3
DK0594576T3 DK91901032T DK91901032T DK0594576T3 DK 0594576 T3 DK0594576 T3 DK 0594576T3 DK 91901032 T DK91901032 T DK 91901032T DK 91901032 T DK91901032 T DK 91901032T DK 0594576 T3 DK0594576 T3 DK 0594576T3
Authority
DK
Denmark
Prior art keywords
immunoassays
monoclonal antibodies
degradation products
prothrombin activation
activation peptides
Prior art date
Application number
DK91901032T
Other languages
Danish (da)
English (en)
Inventor
Marcie J Hursting
Bryan T Butman
Jerald P Steiner
Bryant M Moore
Frederick A Dombrose
Original Assignee
Akzo Nobel Nv
Marcie J Hursting
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23714193&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0594576(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel Nv, Marcie J Hursting filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of DK0594576T3 publication Critical patent/DK0594576T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Exhaust Gas After Treatment (AREA)
  • Transceivers (AREA)
  • Mobile Radio Communication Systems (AREA)
DK91901032T 1989-11-06 1990-11-02 Immunoafprøvninger for og monoklonale antistoffer over for prothrombin-aktivering-peptider og deres nedbrydningsprodukter DK0594576T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43196489A 1989-11-06 1989-11-06
PCT/US1990/006501 WO1991006861A1 (fr) 1989-11-06 1990-11-02 Immunoanalyses de detection d'anticorps monoclonaux contre les peptides d'activation de prothrombine et leurs produits de degradation

Publications (1)

Publication Number Publication Date
DK0594576T3 true DK0594576T3 (da) 2000-02-07

Family

ID=23714193

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91901032T DK0594576T3 (da) 1989-11-06 1990-11-02 Immunoafprøvninger for og monoklonale antistoffer over for prothrombin-aktivering-peptider og deres nedbrydningsprodukter

Country Status (15)

Country Link
US (1) US5830681A (fr)
EP (1) EP0594576B1 (fr)
JP (1) JP2918688B2 (fr)
KR (1) KR100202773B1 (fr)
AT (1) ATE182366T1 (fr)
AU (1) AU655918B2 (fr)
CA (1) CA2071211C (fr)
DE (1) DE69033220T2 (fr)
DK (1) DK0594576T3 (fr)
ES (1) ES2136598T3 (fr)
FI (1) FI109204B (fr)
GR (1) GR3031607T3 (fr)
IE (1) IE903930A1 (fr)
WO (1) WO1991006861A1 (fr)
ZA (1) ZA908778B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3727610A1 (de) 1987-08-19 1989-03-02 Behringwerke Ag Synthetische peptide, gegen diese gerichtete antikoerper und deren verwendung
US5942443A (en) * 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
JP3788519B2 (ja) 1996-06-28 2006-06-21 カリパー・ライフ・サイエンシズ・インコーポレーテッド 微小スケール流体装置の高処理能力スクリーニングアッセイシステム
AUPP460398A0 (en) * 1998-07-10 1998-08-06 Life Therapeutics Limited Lupus anticoagulant
CA2437298A1 (fr) * 2000-02-23 2001-08-30 Besst-Test Aps Methode de correlation de l'activite de coagulation sanguine avec des marqueurs dans des liquides biologiques, par exemple l'urine
US20020098516A1 (en) * 2000-10-03 2002-07-25 Boystown National Research Hospital Immunodiagnostic determination of usher syndrome type IIA
DE10354403A1 (de) 2003-11-20 2005-06-23 Dade Behring Marburg Gmbh Gegen das Prothrombin-Fragment F 1+2 gerichtete Antikörper, ihre Herstellung und Verwendung
DE102004042124B4 (de) * 2004-08-30 2006-07-06 Dade Behring Marburg Gmbh Homogenes Verfahren zur Bestimmung eines Analyten in Gegenwart eines Überschusses von kreuzreagierenden Substanzen
KR100967614B1 (ko) * 2008-03-14 2010-07-05 주식회사 바이오인프라 Ｄｅｓ－Ｒ 프로트롬빈 활성 펩티드 단편 Ｆ２의 혈청 내농도 측정을 통한 암의 진단 및 스크리닝 방법
DE102008049601A1 (de) * 2008-09-30 2010-04-01 Siemens Healthcare Diagnostics Products Gmbh Antikörper zur Bestimmung des Prothrombin-Fragments F2/F1+2 in einem homogenen Immunoassay
EP2437887B1 (fr) 2009-06-04 2016-05-11 Lockheed Martin Corporation Puce microfluidique de plusieurs échantillon pour analyse de dna
AU2011315951B2 (en) 2010-10-15 2015-03-19 Lockheed Martin Corporation Micro fluidic optic design
US9322054B2 (en) 2012-02-22 2016-04-26 Lockheed Martin Corporation Microfluidic cartridge
EP4239338A1 (fr) 2022-03-03 2023-09-06 Siemens Healthcare Diagnostics Products GmbH Essai général destiné à la détermination de l'état du système de coagulation sanguine
WO2023208941A1 (fr) 2022-04-26 2023-11-02 Essilor International Article optique photochromique ayant un revêtement miroir
EP4325224A1 (fr) 2022-08-18 2024-02-21 Siemens Healthcare Diagnostics Products GmbH Essai d'activation plaquettaire destiné au diagnostic d'une thrombocytopénie induite à l'héparine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3727610A1 (de) * 1987-08-19 1989-03-02 Behringwerke Ag Synthetische peptide, gegen diese gerichtete antikoerper und deren verwendung

Also Published As

Publication number Publication date
GR3031607T3 (en) 2000-01-31
AU655918B2 (en) 1995-01-19
WO1991006861A1 (fr) 1991-05-16
CA2071211A1 (fr) 1991-05-07
FI109204B (fi) 2002-06-14
JP2918688B2 (ja) 1999-07-12
IE903930A1 (en) 1991-05-08
EP0594576A1 (fr) 1994-05-04
CA2071211C (fr) 2003-02-18
FI922017L (fi) 1992-05-05
EP0594576A4 (fr) 1993-03-15
EP0594576B1 (fr) 1999-07-21
FI922017A0 (fi) 1992-05-05
KR100202773B1 (ko) 1999-06-15
JPH05504473A (ja) 1993-07-15
US5830681A (en) 1998-11-03
AU6956391A (en) 1991-05-31
DE69033220D1 (de) 1999-08-26
DE69033220T2 (de) 2000-01-20
ES2136598T3 (es) 1999-12-01
ZA908778B (en) 1991-10-30
ATE182366T1 (de) 1999-08-15

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