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DK0561983T3 - Systemer til transdermal indgivelse af lægemidler under anvendelse af sorbitanestere til forbedring af hudgennemtrængelighe - Google Patents

Systemer til transdermal indgivelse af lægemidler under anvendelse af sorbitanestere til forbedring af hudgennemtrængelighe

Info

Publication number
DK0561983T3
DK0561983T3 DK92902108T DK92902108T DK0561983T3 DK 0561983 T3 DK0561983 T3 DK 0561983T3 DK 92902108 T DK92902108 T DK 92902108T DK 92902108 T DK92902108 T DK 92902108T DK 0561983 T3 DK0561983 T3 DK 0561983T3
Authority
DK
Denmark
Prior art keywords
delivery systems
drug delivery
sorbitan esters
transdermal drug
skin permeability
Prior art date
Application number
DK92902108T
Other languages
Danish (da)
English (en)
Inventor
Charles D Ebert
Dinesh Patel
Sonia Heiber
Original Assignee
Theratech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27090035&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0561983(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/702,043 external-priority patent/US5122383A/en
Application filed by Theratech Inc filed Critical Theratech Inc
Application granted granted Critical
Publication of DK0561983T3 publication Critical patent/DK0561983T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
DK92902108T 1990-12-10 1991-12-06 Systemer til transdermal indgivelse af lægemidler under anvendelse af sorbitanestere til forbedring af hudgennemtrængelighe DK0561983T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/625,906 US5202125A (en) 1990-12-10 1990-12-10 Method and systems for administering nitroglycerin transdermally at enhanced transdermal fluxes
US07/702,043 US5122383A (en) 1991-05-17 1991-05-17 Sorbitan esters as skin permeation enhancers
PCT/US1991/009215 WO1992010154A1 (en) 1990-12-10 1991-12-06 Method and systems for administering drugs transdermally using sorbitan esters as skin permeation enhancers

Publications (1)

Publication Number Publication Date
DK0561983T3 true DK0561983T3 (da) 1998-10-19

Family

ID=27090035

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92902108T DK0561983T3 (da) 1990-12-10 1991-12-06 Systemer til transdermal indgivelse af lægemidler under anvendelse af sorbitanestere til forbedring af hudgennemtrængelighe

Country Status (12)

Country Link
US (2) US5202125A (pt)
EP (1) EP0561983B1 (pt)
JP (1) JP2604097B2 (pt)
AT (1) ATE167384T1 (pt)
AU (1) AU656755B2 (pt)
CA (1) CA2098196C (pt)
DE (1) DE69129632T2 (pt)
DK (1) DK0561983T3 (pt)
ES (1) ES2117042T3 (pt)
GR (1) GR3027652T3 (pt)
PT (1) PT99749B (pt)
WO (1) WO1992010154A1 (pt)

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US5613958A (en) * 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
CN1170360A (zh) * 1994-12-21 1998-01-14 瑟垃技术有限公司 具有粘性贴面和剥离密封圆片的经皮输送系统
US20020048596A1 (en) * 1994-12-30 2002-04-25 Gregor Cevc Preparation for the transport of an active substance across barriers
US6024974A (en) * 1995-01-06 2000-02-15 Noven Pharmaceuticals, Inc. Composition and methods for transdermal delivery of acid labile drugs
IL116539A (en) * 1995-01-06 2002-02-10 Noven Pharma Preparations given through the skin of unstable anti-acid drugs
US7094422B2 (en) 1996-02-19 2006-08-22 Acrux Dds Pty Ltd. Topical delivery of antifungal agents
US6929801B2 (en) 1996-02-19 2005-08-16 Acrux Dds Pty Ltd Transdermal delivery of antiparkinson agents
US6923983B2 (en) 1996-02-19 2005-08-02 Acrux Dds Pty Ltd Transdermal delivery of hormones
AUPN814496A0 (en) 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
US6916486B2 (en) 1996-02-19 2005-07-12 Acrux Dds Pty Ltd Transdermal delivery of analgesics
US6916487B2 (en) 1996-02-19 2005-07-12 Acrux Dds Pty Ltd Transdermal delivery of antiemetics
US6998138B2 (en) 1996-02-19 2006-02-14 Acrux Dds Pty. Ltd. Topical delivery of anti-alopecia agents
GR1002807B (el) 1996-06-20 1997-11-13 Lavipharm A.E. Συστημα για την τοπικη θεραπεια της ακμης και μεθοδος παραγωγης του
HUP0201299A2 (en) * 1996-06-20 2002-08-28 Lavipharm Sa Device for topical treatment of acne and its method of manufacture
US6440980B1 (en) * 1996-09-17 2002-08-27 Avanir Pharmaceuticals Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
AU717183B2 (en) * 1996-10-30 2000-03-16 Theratech, Inc. Fatty acid esters of lactic acid salts as permeation enhancers
US7087240B1 (en) 1998-06-25 2006-08-08 Lavipharm Laboratories Inc. Device and method for the treatment of erectile dysfunction
PL345087A1 (en) * 1998-06-25 2001-12-03 Lavipharm Lab A device and method for the treatment of erectile dysfunction
KR20010071049A (ko) * 1998-07-29 2001-07-28 야스이 쇼사꾸 점착성 조성물 및, 각각 당해 조성물을 함유하는 투습성점착 테이프, 점착성 약제 조성물 및 점착 테이프 제제
EP1039880A1 (en) * 1998-10-23 2000-10-04 Idea Innovative Dermale Applikationen GmbH Method for developing, testing and using associates of macromolecules and complex aggregates for improved payload and controllable de/association rates
ATE216875T1 (de) 1999-01-27 2002-05-15 Idea Ag Nichtinvasive impfung durch die haut
PT1031347E (pt) 1999-01-27 2002-09-30 Idea Ag Transporte/imunizacao transnasal com veiculos muitissimo adaptaveis
DE19925338A1 (de) * 1999-06-02 2000-12-07 Lohmann Therapie Syst Lts Substratabschnitte mit erhöhter Lagerstabilität während ihrer Lagerung in Beutelverpackung, sowie Verfahren zu ihrer Herstellung
AU5409699A (en) * 1999-07-05 2001-01-22 Idea Ag A method for the improvement of transport across adaptable semi-permeable barriers
GB9917290D0 (en) * 1999-07-22 1999-09-22 Glaxo Wellcome Spa Pharmaceutical composition
US7083781B2 (en) * 1999-08-19 2006-08-01 Lavipharm S.A. Film forming polymers, methods of use, and devices and applications thereof
GB9930875D0 (en) * 1999-12-24 2000-02-23 Jehan David Patch for transdermal therapy
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US7473432B2 (en) * 2002-10-11 2009-01-06 Idea Ag NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery
US7105263B2 (en) * 2003-12-30 2006-09-12 Samsung Electronics Company Dry toner comprising encapsulated pigment, methods and uses
US20060008432A1 (en) * 2004-07-07 2006-01-12 Sebastiano Scarampi Gilsonite derived pharmaceutical delivery compositions and methods: nail applications
JP2008519784A (ja) * 2004-11-12 2008-06-12 イデア アクチェンゲゼルシャフト 皮膚状態の治療における拡張表面凝集体
US20060188558A1 (en) * 2005-02-18 2006-08-24 Mylan Technologies, Inc. Transdermal systems having control delivery system
ITMI20050477A1 (it) * 2005-03-23 2006-09-24 Bouty S P A Cerotto transdermico
CA2624788C (en) 2005-10-12 2011-04-19 Unimed Pharmaceuticals, Llc Improved testosterone gel and method of use
EP1774964B1 (en) * 2005-10-13 2014-08-06 Nitto Denko Corporation Nicotine transdermal preparation and production method thereof
JP5005277B2 (ja) * 2006-07-13 2012-08-22 日東電工株式会社 貼付剤および貼付製剤
KR20110007088A (ko) * 2008-01-25 2011-01-21 비 앤드 티 에스.알.엘. 화장품 분야에서의 트랜스에스테르화 올리브 오일의 용도
US9302085B2 (en) * 2009-03-11 2016-04-05 The Regents Of The University Of California Methods and compositions for facilitating arterial access
DE102010000661A1 (de) * 2010-01-04 2011-07-07 Acino Ag, 83714 Verfahren und Vorrichtung zur Herstellung einer überlappenden Schutzfolie für ein transdermales therapeutisches System
CN113125596B (zh) * 2021-04-07 2023-01-13 马应龙药业集团股份有限公司 一种高效液相色谱法测定硝酸甘油软膏中有关物质的方法
WO2024006305A1 (en) * 2022-06-27 2024-01-04 Permeatus, Inc. Topical formulations of nitroglycerin

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IL61721A (en) * 1980-12-16 1984-03-30 Blank Izhak Nitroglycerin preparations
CA1218604A (en) * 1981-07-08 1987-03-03 Alec D. Keith Trinitroglycerol sustained release vehicles and preparations therefrom
US4559222A (en) * 1983-05-04 1985-12-17 Alza Corporation Matrix composition for transdermal therapeutic system
US4637930A (en) * 1984-02-08 1987-01-20 Yamanouchi Pharmaceutical Co, Ltd. Transdermal formulation of nicardipine hydrochloride
JPS60174716A (ja) * 1984-02-21 1985-09-09 Yamanouchi Pharmaceut Co Ltd パツチ剤
US4879119A (en) * 1984-02-21 1989-11-07 Yamanouchi Pharmaceutical Co., Ltd. Patch
DE3581188D1 (de) * 1984-07-24 1991-02-07 Key Pharma Klebende schicht zur transdermalen freigabe.
DE3586713T2 (de) * 1984-11-15 1993-05-13 Hercon Lab Vorrichtung zur kontrollierten abgabe von arzneimittelwirkstoffen.
US4751087A (en) * 1985-04-19 1988-06-14 Riker Laboratories, Inc. Transdermal nitroglycerin delivery system
US4615699A (en) * 1985-05-03 1986-10-07 Alza Corporation Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes
US4690683A (en) * 1985-07-02 1987-09-01 Rutgers, The State University Of New Jersey Transdermal varapamil delivery device
US4698062A (en) * 1985-10-30 1987-10-06 Alza Corporation Medical device for pulsatile transdermal delivery of biologically active agents
US4764381A (en) * 1985-12-06 1988-08-16 Key Pharmaceuticals, Inc. Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol
US4836970A (en) * 1987-01-30 1989-06-06 Robbins Edward S Iii Method of extrusion blow-molding container having upper and lower sections of different thickness
US4983395A (en) * 1987-11-12 1991-01-08 Theratech Inc. Device for administering an active agent to the skin or mucosa
US4906475A (en) * 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
US4814168A (en) * 1988-03-04 1989-03-21 Noven Pharmaceuticals, Inc. Transdermal multipolymer drug delivery system
DE69003632T2 (de) * 1989-02-28 1994-02-17 Teijin Ltd Pflaster sowie dessen herstellung.

Also Published As

Publication number Publication date
US5302395A (en) 1994-04-12
AU9141391A (en) 1992-07-08
GR3027652T3 (en) 1998-11-30
AU656755B2 (en) 1995-02-16
DE69129632D1 (de) 1998-07-23
EP0561983A1 (en) 1993-09-29
EP0561983B1 (en) 1998-06-17
CA2098196A1 (en) 1992-06-10
EP0561983A4 (en) 1993-10-20
CA2098196C (en) 1997-01-21
PT99749B (pt) 1999-05-31
US5202125A (en) 1993-04-13
ATE167384T1 (de) 1998-07-15
ES2117042T3 (es) 1998-08-01
PT99749A (pt) 1993-04-30
DE69129632T2 (de) 1998-11-05
HK1013790A1 (en) 1999-09-10
WO1992010154A1 (en) 1992-06-25
JP2604097B2 (ja) 1997-04-23
JPH06503576A (ja) 1994-04-21

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