DK0557519T3 - Fremgangsmåde til fremstilling af sulfonamidderivater af norbornan - Google Patents
Fremgangsmåde til fremstilling af sulfonamidderivater af norbornanInfo
- Publication number
- DK0557519T3 DK0557519T3 DK90914953.6T DK90914953T DK0557519T3 DK 0557519 T3 DK0557519 T3 DK 0557519T3 DK 90914953 T DK90914953 T DK 90914953T DK 0557519 T3 DK0557519 T3 DK 0557519T3
- Authority
- DK
- Denmark
- Prior art keywords
- norbornane
- formula
- represented
- ch2oh
- defined above
- Prior art date
Links
- 229940124530 sulfonamide Drugs 0.000 title 1
- -1 sulfonamide derivatives of norbornane Chemical class 0.000 title 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 2
- HFFXLYHRNRKAPM-UHFFFAOYSA-N 2,4,5-trichloro-n-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C(=CC(Cl)=C(Cl)C=2)Cl)=N1 HFFXLYHRNRKAPM-UHFFFAOYSA-N 0.000 abstract 1
- 238000007167 Hofmann rearrangement reaction Methods 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- RPJTXFAFHGMXLE-UHFFFAOYSA-N bicyclo[2.2.1]heptane-4-carboxamide Chemical compound C1CC2CCC1(C(=O)N)C2 RPJTXFAFHGMXLE-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- UMRZSTCPUPJPOJ-KNVOCYPGSA-N norbornane Chemical compound C1C[C@H]2CC[C@@H]1C2 UMRZSTCPUPJPOJ-KNVOCYPGSA-N 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003461 sulfonyl halides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/20—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27442889 | 1989-10-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0557519T3 true DK0557519T3 (da) | 1997-06-23 |
Family
ID=17541537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90914953.6T DK0557519T3 (da) | 1989-10-18 | 1990-10-16 | Fremgangsmåde til fremstilling af sulfonamidderivater af norbornan |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5124462A (da) |
| EP (1) | EP0557519B1 (da) |
| JP (1) | JP2828334B2 (da) |
| KR (1) | KR0137673B1 (da) |
| AT (1) | ATE154005T1 (da) |
| DE (1) | DE69030884T2 (da) |
| DK (1) | DK0557519T3 (da) |
| ES (1) | ES2104612T3 (da) |
| GR (1) | GR3024010T3 (da) |
| WO (1) | WO1991005765A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3431204B2 (ja) * | 1993-04-22 | 2003-07-28 | 塩野義製薬株式会社 | ノルボルナン型エステル・ヒドロラーゼ |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1278577C (en) * | 1985-11-18 | 1991-01-02 | Tatsuo Tsuri | Bicyclic sulfonamide derivatives |
| DE3720760A1 (de) * | 1987-06-24 | 1989-01-05 | Bayer Ag | Norbornan- und norbornensulfonamide, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel |
| JP2756689B2 (ja) * | 1989-02-20 | 1998-05-25 | 塩野義製薬株式会社 | 置換ヘキセン酸誘導体 |
-
1990
- 1990-10-16 US US07/690,925 patent/US5124462A/en not_active Expired - Fee Related
- 1990-10-16 ES ES90914953T patent/ES2104612T3/es not_active Expired - Lifetime
- 1990-10-16 EP EP90914953A patent/EP0557519B1/en not_active Expired - Lifetime
- 1990-10-16 AT AT90914953T patent/ATE154005T1/de not_active IP Right Cessation
- 1990-10-16 WO PCT/JP1990/001330 patent/WO1991005765A1/ja not_active Ceased
- 1990-10-16 DK DK90914953.6T patent/DK0557519T3/da active
- 1990-10-16 DE DE69030884T patent/DE69030884T2/de not_active Expired - Fee Related
- 1990-10-17 JP JP2279806A patent/JP2828334B2/ja not_active Expired - Fee Related
-
1991
- 1991-06-18 KR KR91700627A patent/KR0137673B1/ko not_active Expired - Fee Related
-
1997
- 1997-07-08 GR GR970401665T patent/GR3024010T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0557519A4 (en) | 1992-02-20 |
| KR920701139A (ko) | 1992-08-11 |
| WO1991005765A1 (fr) | 1991-05-02 |
| DE69030884T2 (de) | 1997-12-18 |
| GR3024010T3 (en) | 1997-10-31 |
| ATE154005T1 (de) | 1997-06-15 |
| ES2104612T3 (es) | 1997-10-16 |
| EP0557519B1 (en) | 1997-06-04 |
| JPH03204852A (ja) | 1991-09-06 |
| EP0557519A1 (en) | 1993-09-01 |
| KR0137673B1 (en) | 1998-05-01 |
| US5124462A (en) | 1992-06-23 |
| DE69030884D1 (de) | 1997-07-10 |
| JP2828334B2 (ja) | 1998-11-25 |
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