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DK0555340T3 - Fremgangsmåde til fremstilling af florfenicol, analoger heraf og oxazolinmellemprodukter dertil - Google Patents

Fremgangsmåde til fremstilling af florfenicol, analoger heraf og oxazolinmellemprodukter dertil

Info

Publication number
DK0555340T3
DK0555340T3 DK91920162.4T DK91920162T DK0555340T3 DK 0555340 T3 DK0555340 T3 DK 0555340T3 DK 91920162 T DK91920162 T DK 91920162T DK 0555340 T3 DK0555340 T3 DK 0555340T3
Authority
DK
Denmark
Prior art keywords
formula
compound
oxazoline
oxazoline compound
pct
Prior art date
Application number
DK91920162.4T
Other languages
English (en)
Inventor
Jon E Clark
Doris P Schumacher
Guang-Zhong Wu
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK0555340T3 publication Critical patent/DK0555340T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK91920162.4T 1990-10-25 1991-10-23 Fremgangsmåde til fremstilling af florfenicol, analoger heraf og oxazolinmellemprodukter dertil DK0555340T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60357590A 1990-10-25 1990-10-25

Publications (1)

Publication Number Publication Date
DK0555340T3 true DK0555340T3 (da) 1995-03-06

Family

ID=24416027

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91920162.4T DK0555340T3 (da) 1990-10-25 1991-10-23 Fremgangsmåde til fremstilling af florfenicol, analoger heraf og oxazolinmellemprodukter dertil

Country Status (19)

Country Link
US (1) US5382673A (da)
EP (1) EP0555340B1 (da)
JP (1) JPH0645580B2 (da)
KR (1) KR960008665B1 (da)
AT (1) ATE115123T1 (da)
AU (1) AU646910B2 (da)
CA (1) CA2094810C (da)
CZ (1) CZ286239B6 (da)
DE (1) DE69105752T2 (da)
DK (1) DK0555340T3 (da)
ES (1) ES2067958T3 (da)
GR (1) GR3015221T3 (da)
HK (1) HK185496A (da)
HU (2) HU9301182D0 (da)
NZ (2) NZ250394A (da)
PL (1) PL166385B1 (da)
RU (1) RU2071468C1 (da)
SK (1) SK281740B6 (da)
WO (1) WO1992007824A1 (da)

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ATE406348T1 (de) 2004-09-23 2008-09-15 Schering Plough Ltd Bekämpfung von parasiten in tieren durch verwendung neuer trifluormethansulfonanilidoximetherderivate
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MX2007015729A (es) * 2005-06-09 2008-02-21 Schering Plough Ltd Control de parasitos en animales con derivados de n-[(feniloxi)fenil]-1,1,1-trifluorometansulfonamida y de n[(fenilsulfanil)fenil]-1,1,1-trifluorometansulfonamida.
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US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
US7518017B2 (en) 2006-02-17 2009-04-14 Idexx Laboratories Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
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CN101600686A (zh) * 2006-12-13 2009-12-09 先灵-普劳有限公司 氯霉素、甲砜霉素及其类似物的水溶性前药
KR20100028537A (ko) * 2007-04-27 2010-03-12 쉐링-프라우 리미티드 사이클로덱스트린을 사용하여 플로르페니콜 및 구조적으로 관련된 항생제의 용해도를 증진시키기 위한 화합물 및 방법
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
DK2957284T3 (da) 2007-06-27 2018-02-05 Du Pont Fremgangsmåde til at kontrollere skadedyr hos dyr
US7550625B2 (en) * 2007-10-19 2009-06-23 Idexx Laboratories Esters of florfenicol
MX2010005087A (es) * 2007-11-09 2010-05-21 Intervet Int Bv Formulacion solida de liberacion rapida, preparacion y uso de la misma.
TWI401023B (zh) 2008-02-06 2013-07-11 Du Pont 中離子農藥
JP2011529895A (ja) * 2008-07-30 2011-12-15 インターベツト・インターナシヨナル・ベー・ベー フロルフェニコール中間体として有用なオキサゾリン保護アミノジオール化合物を調製する方法
MX2012001651A (es) 2009-08-05 2012-03-16 Du Pont Pesticidas mesoionicos.
UA107804C2 (en) 2009-08-05 2015-02-25 Du Pont Mixtures of pesticides mezoionnyh
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
US20120122680A1 (en) 2009-08-05 2012-05-17 E.I. Du Pont De Nemours And Company Mesoionic pesticides
BRPI1002023A2 (pt) 2010-03-01 2011-10-25 Nanocore Biotecnologia S A forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
MX2012013758A (es) 2010-05-27 2013-01-24 Du Pont Forma cristalina de 4-[5-[3-cloro-5-trifluorometil)fenil]-4,5-dihi dro-5-(trifluorometil)-3-isoxazolil]-n-[2-oxo-2-[(2,2,2-trifluoro etil)amino]etil]-1-naftalenocarboxamida.
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
CN102911133B (zh) * 2012-10-31 2014-07-02 绍兴民生医药有限公司 (4r,5r)-2-二氯甲基-4,5-二氢-5-(4-甲砜基苯基)-4-恶唑甲醇的纯化方法
CN103980167B (zh) * 2014-04-17 2016-06-08 天津大学 一种无定形氟苯尼考及其制备方法
CN105218474B (zh) * 2015-10-22 2017-12-05 山东国邦药业股份有限公司 (4r,5r)‑2‑二氯甲基‑4,5‑二氢‑5‑(4‑甲砜基苯基)‑4‑恶唑甲醇的合成方法
CN106278964B (zh) * 2016-07-31 2018-01-16 浙江润康药业有限公司 氟苯尼考的制备方法
CN109678811B (zh) * 2019-01-25 2020-12-29 湖北中牧安达药业有限公司 一种氟苯尼考中间体环合物的不对称制备方法
CN110330463B (zh) * 2019-08-02 2021-05-14 山东国邦药业有限公司 一种氟苯尼考中间体的制备方法
CN113264892B (zh) * 2021-04-05 2022-12-20 复旦大学 一种使用微反应系统连续制备氟苯尼考关键中间体的方法
CN113185473B (zh) * 2021-06-30 2021-10-08 山东国邦药业有限公司 一种氟苯尼考中间体氟甲砜噁唑的制备方法
CN113185474B (zh) * 2021-07-02 2021-11-05 山东国邦药业有限公司 一种氟苯尼考中间体的制备方法

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Also Published As

Publication number Publication date
ATE115123T1 (de) 1994-12-15
AU8927991A (en) 1992-05-26
PL166385B1 (en) 1995-05-31
HK185496A (en) 1996-10-11
DE69105752D1 (de) 1995-01-19
US5382673A (en) 1995-01-17
RU2071468C1 (ru) 1997-01-10
AU646910B2 (en) 1994-03-10
CZ286239B6 (cs) 2000-02-16
HU9301182D0 (en) 1993-08-30
NZ250394A (en) 1994-10-26
SK37793A3 (en) 1993-10-06
HU212617B (en) 1996-09-30
CA2094810A1 (en) 1992-04-26
NZ240319A (en) 1994-10-26
CA2094810C (en) 2002-06-04
EP0555340A1 (en) 1993-08-18
GR3015221T3 (en) 1995-05-31
JPH0645580B2 (ja) 1994-06-15
WO1992007824A1 (en) 1992-05-14
HUT65402A (en) 1994-06-28
SK281740B6 (sk) 2001-07-10
ES2067958T3 (es) 1995-04-01
CZ71093A3 (en) 1994-02-16
KR960008665B1 (en) 1996-06-28
DE69105752T2 (de) 1995-05-11
JPH05507289A (ja) 1993-10-21
EP0555340B1 (en) 1994-12-07

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