DK0554284T3 - Peptid-baserede hæmmere af Hiv-replikation - Google Patents
Peptid-baserede hæmmere af Hiv-replikationInfo
- Publication number
- DK0554284T3 DK0554284T3 DK91917865.7T DK91917865T DK0554284T3 DK 0554284 T3 DK0554284 T3 DK 0554284T3 DK 91917865 T DK91917865 T DK 91917865T DK 0554284 T3 DK0554284 T3 DK 0554284T3
- Authority
- DK
- Denmark
- Prior art keywords
- hiv replication
- peptide
- based inhibitors
- oligopeptide
- inhibition
- Prior art date
Links
- 230000010076 replication Effects 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 102000015636 Oligopeptides Human genes 0.000 abstract 2
- 108010038807 Oligopeptides Proteins 0.000 abstract 2
- ODKSFYDXXFIFQN-SCSAIBSYSA-N D-arginine Chemical compound OC(=O)[C@H](N)CCCNC(N)=N ODKSFYDXXFIFQN-SCSAIBSYSA-N 0.000 abstract 1
- 229930028154 D-arginine Natural products 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 238000012289 standard assay Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60295390A | 1990-10-24 | 1990-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0554284T3 true DK0554284T3 (da) | 1997-01-06 |
Family
ID=24413440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91917865.7T DK0554284T3 (da) | 1990-10-24 | 1991-10-23 | Peptid-baserede hæmmere af Hiv-replikation |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0554284B1 (da) |
| JP (1) | JPH06501938A (da) |
| AT (1) | ATE146483T1 (da) |
| AU (1) | AU660947B2 (da) |
| CA (1) | CA2092075A1 (da) |
| DE (1) | DE69123754T2 (da) |
| DK (1) | DK0554284T3 (da) |
| ES (1) | ES2095959T3 (da) |
| FI (1) | FI931801L (da) |
| GR (1) | GR3022838T3 (da) |
| WO (1) | WO1992007871A1 (da) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5633230A (en) * | 1990-10-24 | 1997-05-27 | Allelix Biopharmaceuticals, Inc. | Treatment of cytomegalovirus infection |
| ATE169822T1 (de) * | 1992-04-23 | 1998-09-15 | Allelix Biopharma | Behandlung von herpesvirus infektion |
| WO1994014464A1 (en) * | 1992-12-22 | 1994-07-07 | Allelix Biopharmaceuticals Inc. | Synergistic compositions containing an antiviral nucleoside analogue and an antiviral oligopeptide |
| US5654398A (en) * | 1993-06-03 | 1997-08-05 | The Regents Of The University Of California | Compositions and methods for inhibiting replication of human immunodeficiency virus-1 |
| WO1995011038A1 (en) * | 1993-10-22 | 1995-04-27 | Allelix Biopharmaceuticals Inc. | Treatment of cytomegalovirus infection |
| US5627194A (en) * | 1993-11-17 | 1997-05-06 | Allelix Biopharmaceuticals Inc. | Anti-viral guanidino-substituted compounds |
| US5441936A (en) * | 1993-12-07 | 1995-08-15 | Houghten Pharmaceuticals, Inc. | Antiviral peptides |
| AU6972798A (en) * | 1997-04-18 | 1998-11-13 | University Of Medicine And Dentistry Of New Jersey | Inhibition of hiv-1 replication by a tat rna-binding domain peptide analog |
| GB2341390B (en) * | 1997-05-21 | 2000-11-08 | Univ Leland Stanford Junior | Composition and method for enhancing transport across biological membranes |
| US5891994A (en) | 1997-07-11 | 1999-04-06 | Thymon L.L.C. | Methods and compositions for impairing multiplication of HIV-1 |
| US6919076B1 (en) | 1998-01-20 | 2005-07-19 | Pericor Science, Inc. | Conjugates of agents and transglutaminase substrate linking molecules |
| US6958148B1 (en) | 1998-01-20 | 2005-10-25 | Pericor Science, Inc. | Linkage of agents to body tissue using microparticles and transglutaminase |
| US6258774B1 (en) * | 1998-03-19 | 2001-07-10 | University Of Medicine And Dentistry Of New Jersey | Carrier for in vivo delivery of a therapeutic agent |
| CA2381425A1 (en) | 1999-08-24 | 2001-03-01 | Cellgate, Inc. | Enhancing drug delivery across and into epithelial tissues using oligo arginine moieties |
| US6669951B2 (en) | 1999-08-24 | 2003-12-30 | Cellgate, Inc. | Compositions and methods for enhancing drug delivery across and into epithelial tissues |
| US7229961B2 (en) | 1999-08-24 | 2007-06-12 | Cellgate, Inc. | Compositions and methods for enhancing drug delivery across and into ocular tissues |
| US6399067B1 (en) | 2000-04-28 | 2002-06-04 | Thymon L.L.C. | Methods and compositions for impairing multiplication of HIV-1 |
| AU8466501A (en) | 2000-07-21 | 2002-02-05 | Essentia Biosystems Inc | Multi-component biological transport systems |
| US7033991B2 (en) | 2001-07-16 | 2006-04-25 | Board Of Supervisors Of Louisiana State University And Agriculture And Mechanical College | Inhibiting furin with polybasic peptides |
| EP1432728A4 (en) * | 2001-08-30 | 2007-10-24 | Praecis Pharm Inc | METHODS AND COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY DISORDERS |
| SG150570A1 (en) | 2004-03-03 | 2009-03-30 | Revance Therapeutics Inc | Compositions and methods for topical diagnostic and therapeutic transport |
| US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| DE602005020137D1 (de) | 2004-05-07 | 2010-05-06 | Univ North Carolina | Verfahren zur verstärkung oder hemmung des insulinähnlichen wachstumsfaktors-i |
| US8187595B2 (en) | 2004-05-07 | 2012-05-29 | The University Of North Carolina At Chapel Hill | Monoclonal antibodies for enhancing or inhibiting insulin-like growth factor-I |
| EP1851247A2 (en) | 2005-02-15 | 2007-11-07 | Thymon L.L.C. | Methods and compositions for impairing multiplication of hiv-1 |
| JP2008531725A (ja) | 2005-03-03 | 2008-08-14 | ルバンス セラピュティックス インク． | オリゴペプチドの局所適用及び経皮送達のための組成物及び方法 |
| EP1861112A4 (en) | 2005-03-03 | 2009-07-22 | Revance Therapeutics Inc | COMPOSITIONS AND METHODS FOR TOPICAL APPLICATION AND TRANSDERMAL DELIVERY OF BOTULINUM TOXINES |
| NZ568216A (en) | 2005-11-17 | 2012-09-28 | Revance Therapeutics Inc | Compositions and methods of topical application and transdermal delivery of botulinum toxins with reduced non-toxin proteins |
| CN102803500B (zh) | 2009-06-05 | 2014-11-19 | 13治疗有限公司 | 免疫调节肽和使用方法 |
| US8580748B2 (en) | 2011-04-06 | 2013-11-12 | 13Therapeutics, Inc. | Peptides for the treatment of hearing |
| KR20150047602A (ko) | 2012-08-31 | 2015-05-04 | 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 | 인슐린 유사 성장 인자 1(igf-1)을 증강 또는 억제시키는 모노클로날 항체 |
| CN103739674A (zh) * | 2013-04-01 | 2014-04-23 | 中国人民解放军军事医学科学院野战输血研究所 | 系列低分子鱼精蛋白模拟肽及其应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3756789A (en) * | 1988-06-16 | 1990-01-12 | St. Louis University | Antagonists of viral transactivating proteins |
-
1991
- 1991-10-23 WO PCT/CA1991/000378 patent/WO1992007871A1/en not_active Ceased
- 1991-10-23 AT AT91917865T patent/ATE146483T1/de not_active IP Right Cessation
- 1991-10-23 EP EP91917865A patent/EP0554284B1/en not_active Expired - Lifetime
- 1991-10-23 ES ES91917865T patent/ES2095959T3/es not_active Expired - Lifetime
- 1991-10-23 DK DK91917865.7T patent/DK0554284T3/da active
- 1991-10-23 FI FI931801A patent/FI931801L/fi not_active Application Discontinuation
- 1991-10-23 CA CA002092075A patent/CA2092075A1/en not_active Abandoned
- 1991-10-23 DE DE69123754T patent/DE69123754T2/de not_active Expired - Fee Related
- 1991-10-23 JP JP3516338A patent/JPH06501938A/ja active Pending
- 1991-10-23 AU AU87259/91A patent/AU660947B2/en not_active Ceased
-
1997
- 1997-03-17 GR GR970400513T patent/GR3022838T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE146483T1 (de) | 1997-01-15 |
| EP0554284A1 (en) | 1993-08-11 |
| ES2095959T3 (es) | 1997-03-01 |
| WO1992007871A1 (en) | 1992-05-14 |
| AU8725991A (en) | 1992-05-26 |
| DE69123754D1 (de) | 1997-01-30 |
| FI931801A7 (fi) | 1993-04-21 |
| GR3022838T3 (en) | 1997-06-30 |
| DE69123754T2 (de) | 1997-04-03 |
| FI931801A0 (fi) | 1993-04-21 |
| CA2092075A1 (en) | 1992-04-25 |
| EP0554284B1 (en) | 1996-12-18 |
| AU660947B2 (en) | 1995-07-13 |
| FI931801L (fi) | 1993-04-21 |
| JPH06501938A (ja) | 1994-03-03 |
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