DK0553234T3 - Luciferasesammensætninger og fremgangsmåder - Google Patents
Luciferasesammensætninger og fremgangsmåderInfo
- Publication number
- DK0553234T3 DK0553234T3 DK91919421T DK91919421T DK0553234T3 DK 0553234 T3 DK0553234 T3 DK 0553234T3 DK 91919421 T DK91919421 T DK 91919421T DK 91919421 T DK91919421 T DK 91919421T DK 0553234 T3 DK0553234 T3 DK 0553234T3
- Authority
- DK
- Denmark
- Prior art keywords
- luciferase
- methods
- luciferin
- coenzyme
- compositions
- Prior art date
Links
- 108060001084 Luciferase Proteins 0.000 title abstract 4
- 239000005089 Luciferase Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 241000254173 Coleoptera Species 0.000 abstract 4
- 238000006243 chemical reaction Methods 0.000 abstract 3
- RGJOEKWQDUBAIZ-IBOSZNHHSA-N CoASH Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCS)O[C@H]1N1C2=NC=NC(N)=C2N=C1 RGJOEKWQDUBAIZ-IBOSZNHHSA-N 0.000 abstract 2
- RGJOEKWQDUBAIZ-UHFFFAOYSA-N coenzime A Natural products OC1C(OP(O)(O)=O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 RGJOEKWQDUBAIZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000005516 coenzyme A Substances 0.000 abstract 2
- 229940093530 coenzyme a Drugs 0.000 abstract 2
- KDTSHFARGAKYJN-UHFFFAOYSA-N dephosphocoenzyme A Natural products OC1C(O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 KDTSHFARGAKYJN-UHFFFAOYSA-N 0.000 abstract 2
- CDMKLKAZVMTVHX-UHFFFAOYSA-N 4,5-dihydro-1,3-thiazol-3-ium-4-carboxylate Chemical compound OC(=O)C1CSC=N1 CDMKLKAZVMTVHX-UHFFFAOYSA-N 0.000 abstract 1
- IGXWBGJHJZYPQS-SSDOTTSWSA-N D-Luciferin Chemical compound OC(=O)[C@H]1CSC(C=2SC3=CC=C(O)C=C3N=2)=N1 IGXWBGJHJZYPQS-SSDOTTSWSA-N 0.000 abstract 1
- CYCGRDQQIOGCKX-UHFFFAOYSA-N Dehydro-luciferin Natural products OC(=O)C1=CSC(C=2SC3=CC(O)=CC=C3N=2)=N1 CYCGRDQQIOGCKX-UHFFFAOYSA-N 0.000 abstract 1
- BJGNCJDXODQBOB-UHFFFAOYSA-N Fivefly Luciferin Natural products OC(=O)C1CSC(C=2SC3=CC(O)=CC=C3N=2)=N1 BJGNCJDXODQBOB-UHFFFAOYSA-N 0.000 abstract 1
- DDWFXDSYGUXRAY-UHFFFAOYSA-N Luciferin Natural products CCc1c(C)c(CC2NC(=O)C(=C2C=C)C)[nH]c1Cc3[nH]c4C(=C5/NC(CC(=O)O)C(C)C5CC(=O)O)CC(=O)c4c3C DDWFXDSYGUXRAY-UHFFFAOYSA-N 0.000 abstract 1
- 238000003149 assay kit Methods 0.000 abstract 1
- 239000005515 coenzyme Substances 0.000 abstract 1
- LIYGYAHYXQDGEP-UHFFFAOYSA-N firefly oxyluciferin Natural products Oc1csc(n1)-c1nc2ccc(O)cc2s1 LIYGYAHYXQDGEP-UHFFFAOYSA-N 0.000 abstract 1
- JJVOROULKOMTKG-UHFFFAOYSA-N oxidized Photinus luciferin Chemical compound S1C2=CC(O)=CC=C2N=C1C1=NC(=O)CS1 JJVOROULKOMTKG-UHFFFAOYSA-N 0.000 abstract 1
- 150000007970 thio esters Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
- C12Y113/12—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
- C12Y113/12007—Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Detergent Compositions (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/580,371 US5283179A (en) | 1990-09-10 | 1990-09-10 | Luciferase assay method |
| PCT/US1991/006474 WO1992004468A1 (en) | 1990-09-10 | 1991-09-09 | Luciferase compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK0553234T3 true DK0553234T3 (da) | 1999-07-26 |
| DK0553234T4 DK0553234T4 (da) | 2005-08-01 |
Family
ID=24320802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91919421T DK0553234T4 (da) | 1990-09-10 | 1991-09-09 | Luciferasesammensætninger og fremgangsmåder |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US5283179A (da) |
| EP (1) | EP0553234B2 (da) |
| JP (2) | JP3171595B2 (da) |
| AT (1) | ATE173298T1 (da) |
| AU (1) | AU649289B2 (da) |
| DE (1) | DE69130482T3 (da) |
| DK (1) | DK0553234T4 (da) |
| ES (1) | ES2126576T5 (da) |
| GR (1) | GR3029352T3 (da) |
| WO (1) | WO1992004468A1 (da) |
Families Citing this family (110)
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|---|---|---|---|---|
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| US7255851B2 (en) * | 1994-07-01 | 2007-08-14 | The Board Of Trustees Of The Leland Stanford Junior University | Non-invasive localization of a light-emitting conjugate in a mammal |
| US6217847B1 (en) | 1994-07-01 | 2001-04-17 | The Board Of Trustees Of The Leland Stanford Junior University | Non-invasive localization of a light-emitting conjugate in a mammal |
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| US6183978B1 (en) * | 1998-09-04 | 2001-02-06 | Tropix, Inc. | Luciferase assay, compositions and kits for use in connection therewith |
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| JP6703484B2 (ja) | 2014-01-29 | 2020-06-03 | プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ | 細胞による取り込み測定のための、標識用試薬としての、キノンでマスクされたプローブ |
| EP3313846B1 (en) * | 2015-06-25 | 2020-05-06 | Promega Corporation | Thienopyrrole compounds and uses thereof as inhibitors of oplophorus-derived luciferases |
| JP7114460B2 (ja) | 2015-06-26 | 2022-08-08 | サノフィ・バイオテクノロジー | モノクローナル抗ＩＬ－１ＲＡｃＰ抗体 |
| US11015176B2 (en) | 2016-03-11 | 2021-05-25 | National Institute Of Advanced Industrial Science And Technology | Nucleic acid encoding a luminescent enzyme protein |
| EP3241845A1 (en) | 2016-05-06 | 2017-11-08 | MAB Discovery GmbH | Humanized anti-il-1r3 antibodies |
| JP7161475B2 (ja) | 2016-12-28 | 2022-10-26 | プロメガ コーポレイション | 官能化ｎａｎｏｌｕｃ阻害剤 |
| EP3401332A1 (en) | 2017-05-08 | 2018-11-14 | MAB Discovery GmbH | Anti-il-1r3 antibodies for use in inflammatory conditions |
| CN111089859A (zh) * | 2018-10-23 | 2020-05-01 | 北京中医药大学 | 新型三磷酸腺苷生物发光测定方法及其用途 |
| RU2744869C2 (ru) * | 2019-08-08 | 2021-03-16 | Общество с ограниченной ответственностью "ПЛАНТА" | Метод и реактивы для детекции активности люциферазы |
| CN113030052B (zh) * | 2021-03-18 | 2022-10-21 | 中国科学院华南植物园 | 一种香蕉采后果实eATP水平的检测方法 |
| CA3217862A1 (en) | 2021-05-05 | 2022-11-10 | Radius Pharmaceuticals, Inc. | Animal model having homologous recombination of mouse pth1 receptor |
| CN114350626A (zh) * | 2021-12-21 | 2022-04-15 | 合肥巅峰生物科技有限公司 | 一种荧光素酶冻干粉稀释反应液 |
| CN114736949B (zh) * | 2022-03-22 | 2024-03-01 | 药科元(上海)生物技术有限公司 | 一种萤火虫荧光素酶报告基因检测试剂盒 |
| AR130550A1 (es) | 2022-09-21 | 2024-12-18 | Sanofi Biotechnology | Anticuerpo anti-il-1r3 humanizado y métodos de uso |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE428379B (sv) * | 1978-05-31 | 1983-06-27 | Lkb Produkter Ab | Bioluminiscens bestemning av atp och reagens herfor |
| DE2828658C3 (de) * | 1978-06-29 | 1981-10-22 | Lkb-Produkter Ab, Stockholm | Verfahren zur photometrischen Bestimmung der Untereinheit B der Creatinkinase und Reagens hierfür |
| US4234681A (en) * | 1978-07-21 | 1980-11-18 | The Regents Of The University Of California | Immobolized light emitting systems |
| US4614712A (en) * | 1983-02-25 | 1986-09-30 | The Upjohn Company | Immunoassays with luciferase labeled ligands or receptors |
| US4665022A (en) * | 1984-02-17 | 1987-05-12 | The Regents Of The University Of California | Bioluminescent assay reagent and method |
| FR2566798B1 (fr) * | 1984-06-27 | 1986-12-12 | Centre Nat Rech Scient | Membrane porteuse de la luciferase pour le dosage de l'atp et son procede de production |
| JPS6163855A (ja) * | 1984-09-05 | 1986-04-02 | Fuji Photo Film Co Ltd | 静電写真用液体現像剤 |
| DK258787D0 (da) * | 1987-05-21 | 1987-05-21 | Foss Electric As N | Fremgangsmaade til bestemmelse af bakteriekoncentration i en proeve |
| GB8722252D0 (en) * | 1987-09-22 | 1987-10-28 | Brewing Res Found | Atp extraction |
| US5283179A (en) * | 1990-09-10 | 1994-02-01 | Promega Corporation | Luciferase assay method |
-
1990
- 1990-09-10 US US07/580,371 patent/US5283179A/en not_active Expired - Lifetime
-
1991
- 1991-09-09 AT AT91919421T patent/ATE173298T1/de not_active IP Right Cessation
- 1991-09-09 DK DK91919421T patent/DK0553234T4/da active
- 1991-09-09 DE DE69130482T patent/DE69130482T3/de not_active Expired - Lifetime
- 1991-09-09 AU AU88583/91A patent/AU649289B2/en not_active Ceased
- 1991-09-09 WO PCT/US1991/006474 patent/WO1992004468A1/en not_active Ceased
- 1991-09-09 EP EP91919421A patent/EP0553234B2/en not_active Expired - Lifetime
- 1991-09-09 ES ES91919421T patent/ES2126576T5/es not_active Expired - Lifetime
- 1991-09-09 JP JP51753191A patent/JP3171595B2/ja not_active Expired - Lifetime
-
1994
- 1994-01-31 US US08/189,558 patent/US5650289A/en not_active Expired - Lifetime
-
1995
- 1995-06-07 US US08/485,834 patent/US5641641A/en not_active Expired - Lifetime
-
1997
- 1997-04-09 US US08/831,781 patent/US5814471A/en not_active Expired - Lifetime
-
1999
- 1999-02-10 GR GR990400439T patent/GR3029352T3/el unknown
-
2000
- 2000-12-28 JP JP2000400335A patent/JP2001224398A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001224398A (ja) | 2001-08-21 |
| US5650289A (en) | 1997-07-22 |
| DE69130482T2 (de) | 1999-05-27 |
| EP0553234A1 (en) | 1993-08-04 |
| EP0553234A4 (da) | 1995-08-02 |
| ES2126576T5 (es) | 2005-12-01 |
| US5283179A (en) | 1994-02-01 |
| EP0553234B1 (en) | 1998-11-11 |
| JP3171595B2 (ja) | 2001-05-28 |
| DK0553234T4 (da) | 2005-08-01 |
| DE69130482T3 (de) | 2006-05-04 |
| EP0553234B2 (en) | 2005-07-13 |
| ATE173298T1 (de) | 1998-11-15 |
| AU8858391A (en) | 1992-03-30 |
| GR3029352T3 (en) | 1999-05-28 |
| JPH06500921A (ja) | 1994-01-27 |
| WO1992004468A1 (en) | 1992-03-19 |
| AU649289B2 (en) | 1994-05-19 |
| US5814471A (en) | 1998-09-29 |
| US5641641A (en) | 1997-06-24 |
| DE69130482D1 (de) | 1998-12-17 |
| ES2126576T3 (es) | 1999-04-01 |
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