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DK0409410T3 - Indenoindolforbindelser - Google Patents

Indenoindolforbindelser

Info

Publication number
DK0409410T3
DK0409410T3 DK90306718.9T DK90306718T DK0409410T3 DK 0409410 T3 DK0409410 T3 DK 0409410T3 DK 90306718 T DK90306718 T DK 90306718T DK 0409410 T3 DK0409410 T3 DK 0409410T3
Authority
DK
Denmark
Prior art keywords
lower alkyl
hydrogen
group
cor
alkyl group
Prior art date
Application number
DK90306718.9T
Other languages
Danish (da)
English (en)
Inventor
Malcolm Sainsbury
Howard G Shertzer
Original Assignee
Univ Bath
Univ Cincinnati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bath, Univ Cincinnati filed Critical Univ Bath
Application granted granted Critical
Publication of DK0409410T3 publication Critical patent/DK0409410T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK90306718.9T 1989-06-22 1990-06-20 Indenoindolforbindelser DK0409410T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8902274A SE8902274D0 (sv) 1989-06-22 1989-06-22 Indenoidole compounds ii

Publications (1)

Publication Number Publication Date
DK0409410T3 true DK0409410T3 (da) 1996-04-29

Family

ID=20376370

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90306718.9T DK0409410T3 (da) 1989-06-22 1990-06-20 Indenoindolforbindelser

Country Status (34)

Country Link
EP (1) EP0409410B1 (fr)
JP (1) JP3064411B2 (fr)
KR (1) KR920702679A (fr)
CN (1) CN1033029C (fr)
AT (1) ATE135688T1 (fr)
BG (1) BG60317B2 (fr)
CA (1) CA2060897A1 (fr)
DD (1) DD297960A5 (fr)
DE (1) DE69025998T2 (fr)
DK (1) DK0409410T3 (fr)
DZ (1) DZ1428A1 (fr)
ES (1) ES2084660T3 (fr)
FI (1) FI100800B (fr)
GR (1) GR3019779T3 (fr)
HR (1) HRP920903B1 (fr)
HU (1) HUT59097A (fr)
IE (1) IE74682B1 (fr)
IL (1) IL94830A (fr)
IS (1) IS3590A7 (fr)
LT (1) LT3675B (fr)
LV (1) LV10253B (fr)
MX (1) MX21244A (fr)
MY (1) MY107311A (fr)
NO (1) NO177932C (fr)
NZ (1) NZ234175A (fr)
PL (1) PL167761B1 (fr)
PT (1) PT94468B (fr)
RO (1) RO111573B1 (fr)
RU (1) RU2104270C1 (fr)
SE (1) SE8902274D0 (fr)
SI (1) SI9011223B (fr)
WO (1) WO1990015799A1 (fr)
YU (1) YU122390A (fr)
ZA (1) ZA904827B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK34893A3 (en) * 1990-10-16 1993-09-08 Univesity Of Bath Indenindole derivatives, process for their preparation and their pharmaceutical compositions
JPH0656669A (ja) * 1992-06-11 1994-03-01 Asahi Breweries Ltd 活性酸素消去作用を持つプテリン誘導体製剤
SE9302431D0 (sv) * 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
AU675141B2 (en) * 1993-07-20 1997-01-23 Adir Et Compagnie (Thia)cycloalkyl(b)indoles, process for preparing them and pharmaceutical compositions containing them
US6288099B1 (en) 1998-12-04 2001-09-11 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
CN1333774A (zh) * 1998-12-04 2002-01-30 美国家庭用品有限公司 以取代苯并呋喃并吲哚和茚并[1,2－b]吲哚作为新的钾通道开放剂
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN101213190A (zh) 2005-07-14 2008-07-02 Irm责任有限公司 用作tpo模拟物的化合物和组合物
DE102006047231B4 (de) 2006-10-04 2009-02-12 Hemmerling, Hans-Jörg, Dr. Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika
AU2012270311B2 (en) * 2011-06-16 2016-04-21 Katholieke Universiteit Leuven K.U. Leuven R & D Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases
EP4585266A3 (fr) 2012-12-14 2025-09-17 Korea Research Institute of Chemical Technology Composé, sel pharmaceutiquement acceptable ou isomère optique de celui-ci, son procédé de préparation et composition pharmaceutique pour la prévention ou le traitement de maladies virales
TWI832045B (zh) 2020-04-20 2024-02-11 瑞士商諾華公司 抗病毒性1,3-二氧代茚化合物
WO2021214080A1 (fr) 2020-04-20 2021-10-28 Novartis Ag Composés de 1,3-di-oxo-indène antiviraux

Also Published As

Publication number Publication date
LV10253B (en) 1995-04-20
HU904825D0 (en) 1992-03-30
DZ1428A1 (fr) 2004-09-13
DE69025998D1 (de) 1996-04-25
NZ234175A (en) 1992-12-23
IL94830A0 (en) 1991-04-15
CN1051554A (zh) 1991-05-22
NO177932B (no) 1995-09-11
PL285752A1 (en) 1991-03-11
KR920702679A (ko) 1992-10-06
SE8902274D0 (sv) 1989-06-22
AU5836990A (en) 1991-01-08
IS3590A7 (is) 1990-12-23
PT94468B (pt) 1997-12-31
NO177932C (no) 1995-12-20
EP0409410B1 (fr) 1996-03-20
HRP920903A2 (hr) 1994-04-30
PT94468A (pt) 1991-02-08
ZA904827B (en) 1991-04-24
HUT59097A (en) 1992-04-28
PL167761B1 (pl) 1995-10-31
WO1990015799A1 (fr) 1990-12-27
FI100800B (fi) 1998-02-27
FI915999A0 (fi) 1991-12-19
YU122390A (sh) 1992-09-07
NO915049L (no) 1992-02-21
RU2104270C1 (ru) 1998-02-10
JP3064411B2 (ja) 2000-07-12
IE74682B1 (en) 1997-07-30
JPH04505923A (ja) 1992-10-15
IL94830A (en) 1996-07-23
CA2060897A1 (fr) 1990-12-23
ATE135688T1 (de) 1996-04-15
IE902247L (en) 1990-12-22
CN1033029C (zh) 1996-10-16
DE69025998T2 (de) 1996-08-08
DD297960A5 (de) 1992-01-30
SI9011223B (sl) 1998-08-31
ES2084660T3 (es) 1996-05-16
MY107311A (en) 1995-11-30
LT3675B (en) 1996-01-25
NO915049D0 (no) 1991-12-20
HRP920903B1 (en) 1998-06-30
SI9011223A (en) 1997-10-31
IE902247A1 (en) 1991-01-16
EP0409410A1 (fr) 1991-01-23
GR3019779T3 (en) 1996-07-31
MX21244A (es) 1994-03-31
LV10253A (lv) 1994-10-20
LTIP912A (en) 1995-03-27
BG60317B2 (bg) 1994-07-25
AU644084B2 (en) 1993-12-02
RO111573B1 (ro) 1996-11-29

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