ATE135688T1 - Indenoindolverbindungen - Google Patents
IndenoindolverbindungenInfo
- Publication number
- ATE135688T1 ATE135688T1 AT90306718T AT90306718T ATE135688T1 AT E135688 T1 ATE135688 T1 AT E135688T1 AT 90306718 T AT90306718 T AT 90306718T AT 90306718 T AT90306718 T AT 90306718T AT E135688 T1 ATE135688 T1 AT E135688T1
- Authority
- AT
- Austria
- Prior art keywords
- lower alkyl
- hydrogen
- group
- cor
- alkyl group
- Prior art date
Links
- RXXXUIOZOITBII-UHFFFAOYSA-N indeno[1,2-g]indole Chemical class C1=C2C=CC=CC2=C2C1=C1N=CC=C1C=C2 RXXXUIOZOITBII-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000003282 alkyl amino group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Toxicology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8902274A SE8902274D0 (sv) | 1989-06-22 | 1989-06-22 | Indenoidole compounds ii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE135688T1 true ATE135688T1 (de) | 1996-04-15 |
Family
ID=20376370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90306718T ATE135688T1 (de) | 1989-06-22 | 1990-06-20 | Indenoindolverbindungen |
Country Status (34)
| Country | Link |
|---|---|
| EP (1) | EP0409410B1 (de) |
| JP (1) | JP3064411B2 (de) |
| KR (1) | KR920702679A (de) |
| CN (1) | CN1033029C (de) |
| AT (1) | ATE135688T1 (de) |
| BG (1) | BG60317B2 (de) |
| CA (1) | CA2060897A1 (de) |
| DD (1) | DD297960A5 (de) |
| DE (1) | DE69025998T2 (de) |
| DK (1) | DK0409410T3 (de) |
| DZ (1) | DZ1428A1 (de) |
| ES (1) | ES2084660T3 (de) |
| FI (1) | FI100800B (de) |
| GR (1) | GR3019779T3 (de) |
| HR (1) | HRP920903B1 (de) |
| HU (1) | HUT59097A (de) |
| IE (1) | IE74682B1 (de) |
| IL (1) | IL94830A (de) |
| IS (1) | IS3590A7 (de) |
| LT (1) | LT3675B (de) |
| LV (1) | LV10253B (de) |
| MX (1) | MX21244A (de) |
| MY (1) | MY107311A (de) |
| NO (1) | NO177932C (de) |
| NZ (1) | NZ234175A (de) |
| PL (1) | PL167761B1 (de) |
| PT (1) | PT94468B (de) |
| RO (1) | RO111573B1 (de) |
| RU (1) | RU2104270C1 (de) |
| SE (1) | SE8902274D0 (de) |
| SI (1) | SI9011223B (de) |
| WO (1) | WO1990015799A1 (de) |
| YU (1) | YU122390A (de) |
| ZA (1) | ZA904827B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2094024A1 (en) * | 1990-10-16 | 1992-04-17 | Malcolm Sainsbury | Indenoindole compounds |
| JPH0656669A (ja) * | 1992-06-11 | 1994-03-01 | Asahi Breweries Ltd | 活性酸素消去作用を持つプテリン誘導体製剤 |
| SE9302431D0 (sv) * | 1993-07-16 | 1993-07-16 | Ab Astra | Use of indenoindole compounds |
| CA2128283A1 (fr) * | 1993-07-20 | 1995-01-21 | Paul Caubere | (thia)cycloalkyl¬b|indoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US6288099B1 (en) | 1998-12-04 | 2001-09-11 | American Home Products Corporation | Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers |
| WO2000034285A2 (en) * | 1998-12-04 | 2000-06-15 | American Home Products Corporation | Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers |
| FR2826009B1 (fr) * | 2001-06-13 | 2003-08-15 | Servier Lab | Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| PL1910338T3 (pl) | 2005-07-14 | 2011-02-28 | Irm Llc | Związki heterotetracykliczne jako mimetyki TPO |
| DE102006047231B4 (de) * | 2006-10-04 | 2009-02-12 | Hemmerling, Hans-Jörg, Dr. | Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika |
| EP3597184A3 (de) * | 2011-06-16 | 2020-04-22 | Korea Research Institute of Chemical Technology | Indanonderivate, pharmazeutisch zulässige salze oder optische isomere davon, herstellungsverfahren dafür und pharmazeutische zusammensetzungen damit als wirkstoff zur verhinderung oder behandlung von virenerkrankungen |
| PL3882244T3 (pl) | 2012-12-14 | 2025-06-16 | Korea Research Institute Of Chemical Technology | ZWIĄZEK, JEGO FARMACEUTYCZNIE DOPUSZCZALNA SÓL LUB IZOMER OPTYCZNY, SPOSÓB ICH WYTWARZANIA i ZAWIERAJĄCA JE, JAKO SKŁADNIK AKTYWNY, KOMPOZYCJA FARMACEUTYCZNA DO PROFILAKTYKI LUB LECZENIA CHORÓB WIRUSOWYCH |
| TWI851890B (zh) | 2020-04-20 | 2024-08-11 | 瑞士商諾華公司 | 抗病毒性1,3-二氧代茚化合物 |
| KR20230024887A (ko) | 2020-04-20 | 2023-02-21 | 노파르티스 아게 | 항바이러스성 1,3-디-옥소-인덴 화합물 |
-
1989
- 1989-06-22 SE SE8902274A patent/SE8902274D0/xx unknown
-
1990
- 1990-06-13 IS IS3590A patent/IS3590A7/is unknown
- 1990-06-20 EP EP90306718A patent/EP0409410B1/de not_active Expired - Lifetime
- 1990-06-20 IE IE224790A patent/IE74682B1/en not_active IP Right Cessation
- 1990-06-20 AT AT90306718T patent/ATE135688T1/de active
- 1990-06-20 DZ DZ900114A patent/DZ1428A1/fr active
- 1990-06-20 DE DE69025998T patent/DE69025998T2/de not_active Expired - Fee Related
- 1990-06-20 HU HU904825A patent/HUT59097A/hu unknown
- 1990-06-20 RO RO149127A patent/RO111573B1/ro unknown
- 1990-06-20 WO PCT/GB1990/000949 patent/WO1990015799A1/en not_active Ceased
- 1990-06-20 JP JP2508940A patent/JP3064411B2/ja not_active Expired - Fee Related
- 1990-06-20 RU SU5010937A patent/RU2104270C1/ru active
- 1990-06-20 PL PL90285752A patent/PL167761B1/pl unknown
- 1990-06-20 MX MX21244A patent/MX21244A/es unknown
- 1990-06-20 ES ES90306718T patent/ES2084660T3/es not_active Expired - Lifetime
- 1990-06-20 CA CA002060897A patent/CA2060897A1/en not_active Abandoned
- 1990-06-20 DK DK90306718.9T patent/DK0409410T3/da active
- 1990-06-21 MY MYPI90001050A patent/MY107311A/en unknown
- 1990-06-21 ZA ZA904827A patent/ZA904827B/xx unknown
- 1990-06-21 IL IL9483090A patent/IL94830A/en not_active IP Right Cessation
- 1990-06-21 NZ NZ234175A patent/NZ234175A/xx unknown
- 1990-06-21 DD DD90341939A patent/DD297960A5/de not_active IP Right Cessation
- 1990-06-22 SI SI9011223A patent/SI9011223B/sl unknown
- 1990-06-22 CN CN90104933A patent/CN1033029C/zh not_active Expired - Fee Related
- 1990-06-22 PT PT94468A patent/PT94468B/pt not_active IP Right Cessation
- 1990-06-22 YU YU122390A patent/YU122390A/sh unknown
-
1991
- 1991-12-19 FI FI915999A patent/FI100800B/fi active
- 1991-12-20 BG BG095667A patent/BG60317B2/bg unknown
- 1991-12-20 NO NO915049A patent/NO177932C/no unknown
- 1991-12-23 KR KR1019910701951A patent/KR920702679A/ko not_active Ceased
-
1992
- 1992-10-02 HR HRP-1223/90A patent/HRP920903B1/xx not_active IP Right Cessation
-
1993
- 1993-06-14 LV LVP-93-568A patent/LV10253B/xx unknown
- 1993-08-30 LT LTIP912A patent/LT3675B/lt not_active IP Right Cessation
-
1996
- 1996-04-29 GR GR960401159T patent/GR3019779T3/el unknown
Also Published As
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