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DK0495953T3 - 10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo-(7.2.0.0.3.8)undec-2-en-carboxylsyreestere og fremgangsmåde til fremstilling deraf - Google Patents

10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo-(7.2.0.0.3.8)undec-2-en-carboxylsyreestere og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0495953T3
DK0495953T3 DK91914351.1T DK91914351T DK0495953T3 DK 0495953 T3 DK0495953 T3 DK 0495953T3 DK 91914351 T DK91914351 T DK 91914351T DK 0495953 T3 DK0495953 T3 DK 0495953T3
Authority
DK
Denmark
Prior art keywords
azatricyclo
undec
ene
oxo
hydroxyethyl
Prior art date
Application number
DK91914351.1T
Other languages
English (en)
Inventor
Alcide Perboni
Tino Rossi
Giovanni Gaviraghi
Antonella Ursini
Giorgio Tarzia
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909018330A external-priority patent/GB9018330D0/en
Priority claimed from GB919104770A external-priority patent/GB9104770D0/en
Application filed by Glaxo Spa filed Critical Glaxo Spa
Application granted granted Critical
Publication of DK0495953T3 publication Critical patent/DK0495953T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
DK91914351.1T 1990-08-21 1991-08-20 10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo-(7.2.0.0.3.8)undec-2-en-carboxylsyreestere og fremgangsmåde til fremstilling deraf DK0495953T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909018330A GB9018330D0 (en) 1990-08-21 1990-08-21 Heterocyclic compounds
GB919104770A GB9104770D0 (en) 1991-03-07 1991-03-07 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
DK0495953T3 true DK0495953T3 (da) 1994-07-18

Family

ID=26297540

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91914351.1T DK0495953T3 (da) 1990-08-21 1991-08-20 10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo-(7.2.0.0.3.8)undec-2-en-carboxylsyreestere og fremgangsmåde til fremstilling deraf

Country Status (32)

Country Link
US (1) US5587374A (da)
EP (1) EP0495953B1 (da)
JP (2) JP3151215B2 (da)
KR (1) KR0169147B1 (da)
CN (1) CN1030917C (da)
AP (1) AP238A (da)
AT (1) ATE106887T1 (da)
AU (1) AU647178B2 (da)
CA (1) CA2067741C (da)
CY (1) CY2037A (da)
CZ (1) CZ280942B6 (da)
DE (1) DE69102415T2 (da)
DK (1) DK0495953T3 (da)
ES (1) ES2054502T3 (da)
FI (1) FI97136C (da)
HK (1) HK19495A (da)
HR (1) HRP940556B1 (da)
HU (2) HUT61024A (da)
IE (1) IE66122B1 (da)
IL (1) IL99248A (da)
MX (1) MX9100743A (da)
MY (1) MY106997A (da)
NO (1) NO300176B1 (da)
NZ (1) NZ239474A (da)
OA (1) OA09578A (da)
PL (1) PL169425B1 (da)
PT (1) PT98729B (da)
SG (1) SG169494G (da)
SI (1) SI9111427B (da)
SK (1) SK278470B6 (da)
WO (1) WO1992003437A1 (da)
YU (1) YU48079B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9104838D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
AP294A (en) * 1992-08-31 1993-12-28 Glaxo Spa "10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo-(7.2.0.0.3.8) undec-2-ene-2-carboxylic acid derivatives".
GB9218781D0 (en) * 1992-09-04 1992-10-21 Glaxo Spa Heterocyclic derivatives
IN188720B (da) * 1997-11-06 2002-11-02 Panacea Biotec Ltd
CA2465336C (en) 2001-11-05 2009-04-28 Sumitomo Pharmaceuticals Co., Ltd. Novel carbapenem compounds
US7468364B2 (en) * 2003-04-08 2008-12-23 Dainippon Sumitomo Pharma Co., Ltd. Carbapenem compounds
EP1785426A4 (en) * 2004-09-03 2008-02-20 Dainippon Sumitomo Pharma Co NEW CARBAPENEM DERIVATIVE
US20090029964A1 (en) * 2005-03-25 2009-01-29 Makoto Sunagawa Novel carbapenem compound
EP2085084A1 (en) 2008-01-29 2009-08-05 LEK Pharmaceuticals D.D. Use of inhibitor of beta-lactamases and its combination with beta-lactam antibiotics
EP2135871A1 (en) * 2008-06-18 2009-12-23 LEK Pharmaceuticals D.D. New trinem antibiotics and inhibitors of beta-lactamases
CN110869016B (zh) 2017-05-08 2023-09-12 葛兰素史密斯克莱知识产权发展有限公司 用于治疗分枝杆菌感染的山费培南或其盐或酯

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1433131A (en) * 1972-03-13 1976-04-22 Astra Laekemedel Ab Penicillins
GB1425571A (en) * 1972-03-13 1976-02-18 Astra Laekemedel Ab Penicillins and cephaosporins
DE2811514A1 (de) * 1977-03-19 1978-09-21 Beecham Group Ltd Ester der 7-oxo-1-azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept- 2-en-2-carbonsaeure und deren derivate, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zubereitungen
US4374848A (en) * 1981-09-14 1983-02-22 Merck & Co., Inc. 6-(1-Hydroxyethyl)cyclonocardicin
US4374849A (en) * 1981-09-14 1983-02-22 Merck & Co., Inc. 6-Amidocyclonocardicins
CZ435990A3 (cs) 1989-09-08 1999-11-17 Glaxo S.P.A. Kyselina 10-(1-hydroxyethyl)-11-oxo-1-azatricyklo/7,2,0,03,8/-undec-2en-2-karboxylová a její deriváty, způsob jejich výroby, použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem
AU636913B2 (en) * 1989-10-11 1993-05-13 Takeda Chemical Industries Ltd. Tricyclic carbapenem compounds
GB9104832D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
GB9104838D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds

Also Published As

Publication number Publication date
KR0169147B1 (en) 1999-01-15
FI921717A0 (fi) 1992-04-16
PL169425B1 (pl) 1996-07-31
CZ121392A3 (en) 1993-04-14
CN1060094A (zh) 1992-04-08
AU647178B2 (en) 1994-03-17
OA09578A (en) 1993-01-31
JP2000351730A (ja) 2000-12-19
MX9100743A (es) 1992-04-01
SG169494G (en) 1995-04-28
IL99248A0 (en) 1992-07-15
FI921717L (fi) 1992-04-16
DE69102415T2 (de) 1994-10-13
PT98729A (pt) 1992-07-31
SK121392A3 (en) 1997-06-04
ATE106887T1 (de) 1994-06-15
EP0495953B1 (en) 1994-06-08
HU9201303D0 (en) 1992-07-28
HRP940556A2 (en) 1996-06-30
SK278470B6 (en) 1997-06-04
US5587374A (en) 1996-12-24
YU48079B (sh) 1997-01-08
MY106997A (en) 1995-08-30
AP9100320A0 (en) 1991-10-31
AP238A (en) 1993-02-04
CA2067741C (en) 2002-01-01
NO921521L (no) 1992-06-22
DE69102415D1 (de) 1994-07-14
NZ239474A (en) 1994-06-27
JPH05502044A (ja) 1993-04-15
NO300176B1 (no) 1997-04-21
FI97136B (fi) 1996-07-15
HU211584A9 (en) 1995-12-28
NO921521D0 (no) 1992-04-15
CZ280942B6 (cs) 1996-05-15
ES2054502T3 (es) 1994-08-01
JP3461786B2 (ja) 2003-10-27
WO1992003437A1 (en) 1992-03-05
FI97136C (fi) 1996-10-25
IE912944A1 (en) 1992-02-26
HUT61024A (en) 1992-11-30
CY2037A (en) 1998-02-20
SI9111427A (en) 1996-12-31
KR920702361A (ko) 1992-09-03
CN1030917C (zh) 1996-02-07
AU8421291A (en) 1992-03-17
EP0495953A1 (en) 1992-07-29
SI9111427B (sl) 2000-10-31
YU142791A (sh) 1994-01-20
HRP940556B1 (en) 2000-06-30
CA2067741A1 (en) 1992-02-22
PT98729B (pt) 1999-01-29
HK19495A (en) 1995-02-17
IE66122B1 (en) 1995-12-13
IL99248A (en) 1996-01-31
JP3151215B2 (ja) 2001-04-03

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