DK0471295T3 - Reagens til udfældning af proteiner - Google Patents

Reagens til udfældning af proteiner

Info

Publication number: DK0471295T3
Authority: DK; Denmark
Prior art keywords: precipitation reagent; analytes; proteins; determination; test sample
Prior art date: 1990-08-15

Application number

DK91113331.2T

Other languages

English (en)

Inventor

Victoria P Meucci

Mariola B Zajac

Elizabeth A Simpson

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-15

Filing date

1991-08-08

Publication date

1996-04-09

1991-08-08 Application filed by Abbott Lab filed Critical Abbott Lab

1996-04-09 Application granted granted Critical

1996-04-09 Publication of DK0471295T3 publication Critical patent/DK0471295T3/da

Links

239000003153 chemical reaction reagent Substances 0.000 title abstract 5
230000006920 protein precipitation Effects 0.000 title 1
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 5
238000001556 precipitation Methods 0.000 abstract 4
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
230000002209 hydrophobic effect Effects 0.000 abstract 3
102000014914 Carrier Proteins Human genes 0.000 abstract 2
108091008324 binding proteins Proteins 0.000 abstract 2
238000003018 immunoassay Methods 0.000 abstract 2
230000002452 interceptive effect Effects 0.000 abstract 2
230000009870 specific binding Effects 0.000 abstract 2
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
102000001554 Hemoglobins Human genes 0.000 abstract 1
108010054147 Hemoglobins Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
229930182912 cyclosporin Natural products 0.000 abstract 1
238000004925 denaturation Methods 0.000 abstract 1
230000036425 denaturation Effects 0.000 abstract 1
WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
230000010287 polarization Effects 0.000 abstract 1
239000002244 precipitate Substances 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
150000003751 zinc Chemical class 0.000 abstract 1
NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 abstract 1
229960001763 zinc sulfate Drugs 0.000 abstract 1
229910000368 zinc sulfate Inorganic materials 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials

Landscapes

Health & Medical Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
General Physics & Mathematics (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Sampling And Sample Adjustment (AREA)
Separation Of Suspended Particles By Flocculating Agents (AREA)

DK91113331.2T 1990-08-15 1991-08-08 Reagens til udfældning af proteiner DK0471295T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/567,853 US5135875A (en)	1990-08-15	1990-08-15	Protein precipitation reagent

Publications (1)

Publication Number	Publication Date
DK0471295T3 true DK0471295T3 (da)	1996-04-09

Family

ID=24268905

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91113331.2T DK0471295T3 (da)	1990-08-15	1991-08-08	Reagens til udfældning af proteiner

Country Status (10)

Country	Link
US (1)	US5135875A (da)
EP (1)	EP0471295B1 (da)
JP (1)	JPH04233460A (da)
AT (1)	ATE130095T1 (da)
AU (1)	AU642522B2 (da)
CA (1)	CA2048314A1 (da)
DE (1)	DE69114403T2 (da)
DK (1)	DK0471295T3 (da)
ES (1)	ES2082059T3 (da)
GR (1)	GR3018907T3 (da)

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US4734378A (en) *	1985-06-26	1988-03-29	Abbott Laboratories	Precipitation of interfering proteins in fluorescence polarization immunoassay for digoxin
NO890029D0 (no) *	1989-01-04	1989-01-04	Axis Research	Nye modifiserte peptider og proteiner for in vitro diagnoser (diabetes).

1990
- 1990-08-15 US US07/567,853 patent/US5135875A/en not_active Expired - Fee Related
1991
- 1991-08-01 CA CA002048314A patent/CA2048314A1/en not_active Abandoned
- 1991-08-08 ES ES91113331T patent/ES2082059T3/es not_active Expired - Lifetime
- 1991-08-08 DE DE69114403T patent/DE69114403T2/de not_active Expired - Fee Related
- 1991-08-08 EP EP91113331A patent/EP0471295B1/en not_active Expired - Lifetime
- 1991-08-08 AT AT91113331T patent/ATE130095T1/de active
- 1991-08-08 DK DK91113331.2T patent/DK0471295T3/da active
- 1991-08-14 AU AU82472/91A patent/AU642522B2/en not_active Ceased
- 1991-08-15 JP JP3205211A patent/JPH04233460A/ja active Pending
1996
- 1996-02-07 GR GR960400313T patent/GR3018907T3/el unknown

Also Published As

Publication number	Publication date
AU642522B2 (en)	1993-10-21
ES2082059T3 (es)	1996-03-16
EP0471295B1 (en)	1995-11-08
DE69114403D1 (de)	1995-12-14
GR3018907T3 (en)	1996-05-31
US5135875A (en)	1992-08-04
ATE130095T1 (de)	1995-11-15
DE69114403T2 (de)	1996-06-05
AU8247291A (en)	1992-02-20
JPH04233460A (ja)	1992-08-21
CA2048314A1 (en)	1992-02-16
EP0471295A1 (en)	1992-02-19

Publication	Publication Date	Title
DK0471295T3 (da)	1996-04-09	Reagens til udfældning af proteiner
US6114180A (en)	2000-09-05	Synthetic calibrators for use in immunoassays, comprising the analytes or partial sequences thereof which are conjugated to inert carrier molecules
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DE69233674D1 (de)	2007-02-15	Homogenes Testsystem zur Bestimmung eines Analytes
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ES2079368T3 (es)	1996-01-16	Metodo y reactivos para detectar anfetaminas y/o d-meta-anfetaminas en muestras biologicas.
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IL124093A (en)	2000-08-31	Cyanide containing hemoglobin reagent composition and method for the determination of hemoglobin in blood
DK0598903T3 (da)	1998-03-02	Reagens til bestemmelse af (1-3)-beta-D-glucan
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Sims et al.	1977	Determination of serum creatinine by reaction with methyl-3, 5-dinitrobenzoate in methyl sulfoxide
AT400199B (de)	1995-10-25	Aufbereitung von lipoproteinhältigen proben
AU3106589A (en)	1989-09-14	Agent, for immunochemical assays, containing amine oxides
MISOGIANES	1979	A physiochemical and spectral characterization of the extrapallial fluid of Mytilus edulis