ES2079368T3 - Metodo y reactivos para detectar anfetaminas y/o d-meta-anfetaminas en muestras biologicas. - Google Patents
Metodo y reactivos para detectar anfetaminas y/o d-meta-anfetaminas en muestras biologicas.Info
- Publication number
- ES2079368T3 ES2079368T3 ES89119701T ES89119701T ES2079368T3 ES 2079368 T3 ES2079368 T3 ES 2079368T3 ES 89119701 T ES89119701 T ES 89119701T ES 89119701 T ES89119701 T ES 89119701T ES 2079368 T3 ES2079368 T3 ES 2079368T3
- Authority
- ES
- Spain
- Prior art keywords
- sample
- reagents
- amphetamines
- methamphetamine
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 6
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 3
- 239000012472 biological sample Substances 0.000 title abstract 2
- MYWUZJCMWCOHBA-SECBINFHSA-N levmetamfetamine Chemical compound CN[C@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-SECBINFHSA-N 0.000 abstract 3
- 229950007554 levmetamfetamine Drugs 0.000 abstract 3
- 239000000523 sample Substances 0.000 abstract 3
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 abstract 2
- 229940025084 amphetamine Drugs 0.000 abstract 2
- 238000003018 immunoassay Methods 0.000 abstract 2
- DZGWFCGJZKJUFP-UHFFFAOYSA-N Tyramine Natural products NCCC1=CC=C(O)C=C1 DZGWFCGJZKJUFP-UHFFFAOYSA-N 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000013060 biological fluid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000599 controlled substance Substances 0.000 abstract 1
- 230000009260 cross reactivity Effects 0.000 abstract 1
- 238000002875 fluorescence polarization Methods 0.000 abstract 1
- KHIWWQKSHDUIBK-UHFFFAOYSA-N periodic acid Chemical compound OI(=O)(=O)=O KHIWWQKSHDUIBK-UHFFFAOYSA-N 0.000 abstract 1
- ULSIYEODSMZIPX-UHFFFAOYSA-N phenylethanolamine Chemical compound NCC(O)C1=CC=CC=C1 ULSIYEODSMZIPX-UHFFFAOYSA-N 0.000 abstract 1
- 239000000700 radioactive tracer Substances 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 108010053455 riboflavin-binding protein Proteins 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 229960003732 tyramine Drugs 0.000 abstract 1
- DZGWFCGJZKJUFP-UHFFFAOYSA-O tyraminium Chemical compound [NH3+]CCC1=CC=C(O)C=C1 DZGWFCGJZKJUFP-UHFFFAOYSA-O 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
EL INVENTO RELATA UN METODO PARA DETERMINAR SI HAY ANFETAMINA Y D-META-ANFETAMINA EN UN FLUIDO BIOLOGICO, COMO LA ORINA. EN PARTICULAS, EL INVENTO RELATA LAS MEJORAS EN UN PROCEDIMIENTO DE POLARIZACION PARA DETERMINAR LA PRESENCIA DE ANFETAMINA Y D-METAANFETAMINA EN UNA PRUEBA SIMPLE. EL PROCESO DESCRIBE EL PRETRATAMIENTO DE UN EJEMPLO BIOLOGICO PARA ELIMINAR REACTIVOS COMO EL (BETA)-HIDROXI-FENTIL-AMINA PREINCUBANDO LA MUESTRA EN UNA DISOLUCION ACUOSA CON UN PH DE 4,0 A 7,5 SIN AJUSTARSE A UN PH ALCALINO Y CONTACTANDO CON LA MUESTRA PROTEINA DE RIBOFLACINA PARA REDUCIR LA INTERFERENCIA DE LOS COMPONENTES FLUORESCENTES DE LA MUESTRA. EL PROCESO MANTIENE LA REACTIVIDAD DE LA TIRAMINA EN UN 0,4% Y LA I-META-ANFETAMINA EN U/N 5,1% Y ELIMINAN LA NECESIDAD DE CONTROLAR CIERTAS SUSTANCIAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26536188A | 1988-10-28 | 1988-10-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2079368T3 true ES2079368T3 (es) | 1996-01-16 |
Family
ID=23010119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89119701T Expired - Lifetime ES2079368T3 (es) | 1988-10-28 | 1989-10-24 | Metodo y reactivos para detectar anfetaminas y/o d-meta-anfetaminas en muestras biologicas. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0371253B1 (es) |
| JP (1) | JPH02170050A (es) |
| AT (1) | ATE127928T1 (es) |
| AU (1) | AU634985B2 (es) |
| CA (1) | CA2001696A1 (es) |
| DE (1) | DE68924243T2 (es) |
| ES (1) | ES2079368T3 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5362852A (en) * | 1991-09-27 | 1994-11-08 | Pfizer Inc. | Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties |
| US5470997A (en) * | 1992-04-06 | 1995-11-28 | Biosite Diagnostics Incorporated | Amphetamine derivatives and protein and polypeptide amphetamine derivative conjugates and labels |
| US5378634A (en) * | 1992-08-20 | 1995-01-03 | Matsushita Electric Industrial Co., Ltd. | Labelling color for detecting methamphetamine |
| US6306616B1 (en) | 1998-03-27 | 2001-10-23 | Microgenics Corporation | Adsorption type confirmatory assays |
| GB2361473C (en) | 2000-03-08 | 2005-06-28 | Microgenics Corp | Ecstasy-class analogs and use of same in detection of ecstasy-class compounds |
| US6472228B2 (en) * | 2000-12-04 | 2002-10-29 | Lifepoint, Inc. | Composition and methods for synthesis of novel tracers for detecting amphetamine and methamphetamine in samples |
| US20030170917A1 (en) * | 2002-03-01 | 2003-09-11 | Roche Diagnostics Corporation | Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes |
| GB2404022B (en) | 2004-06-14 | 2005-08-10 | Cozart Bioscience Ltd | Competitive assays for the detection of methamphetamine group drugs |
| GB2404023B (en) | 2004-07-02 | 2005-07-06 | Cozart Bioscience Ltd | Delta-9-tetrahydrocannabinol detection method |
| CN102590493A (zh) * | 2012-02-17 | 2012-07-18 | 南开大学 | 一种邻苯二甲酸二乙酯荧光偏振免疫检测试剂盒 |
| BR112020021157A2 (pt) * | 2018-04-19 | 2021-01-19 | Ellie LLC | Método de tratamento e teste de uma amostra que compreende um analito |
| CN115078556B (zh) * | 2021-03-11 | 2023-10-24 | 远大生命科学(武汉)有限公司 | 一种同时测定多西拉敏与吡哆醇含量的方法 |
| CN113461492B (zh) * | 2021-06-30 | 2022-11-11 | 中国科学院上海微系统与信息技术研究所 | 一种基于手性晶体界面选择性解聚的液相荧光检测体系 |
| CN114354781A (zh) * | 2021-12-15 | 2022-04-15 | 广西桂林锐德检测认证技术有限公司 | 一种同时测定食品中5种非法添加物的方法 |
| CN114890958B (zh) * | 2022-02-23 | 2023-10-20 | 四川警察学院 | 双光子染料化合物、其制备方法及其应用 |
| CN118330096B (zh) * | 2024-06-12 | 2024-09-13 | 长沙市公安局 | 一种液态餐厨垃圾中毒品的检测方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU162378B (es) * | 1970-06-10 | 1973-02-28 | ||
| US4939264A (en) * | 1986-07-14 | 1990-07-03 | Abbott Laboratories | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies |
| US4952336A (en) * | 1987-02-03 | 1990-08-28 | Abbott Laboratories | Fluorescence polymerization immunoassay for amphetamine/methamphetamine |
| US4868132A (en) * | 1987-02-03 | 1989-09-19 | Abbott Laboratories | Fluorescence polarization immunoassay for amphetamine/methamphetamine |
-
1989
- 1989-10-24 ES ES89119701T patent/ES2079368T3/es not_active Expired - Lifetime
- 1989-10-24 AT AT89119701T patent/ATE127928T1/de not_active IP Right Cessation
- 1989-10-24 DE DE68924243T patent/DE68924243T2/de not_active Expired - Fee Related
- 1989-10-24 EP EP89119701A patent/EP0371253B1/en not_active Expired - Lifetime
- 1989-10-26 AU AU43807/89A patent/AU634985B2/en not_active Ceased
- 1989-10-27 CA CA002001696A patent/CA2001696A1/en not_active Abandoned
- 1989-10-28 JP JP1281627A patent/JPH02170050A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE68924243T2 (de) | 1996-03-28 |
| EP0371253A2 (en) | 1990-06-06 |
| AU4380789A (en) | 1990-05-03 |
| EP0371253B1 (en) | 1995-09-13 |
| ATE127928T1 (de) | 1995-09-15 |
| DE68924243D1 (de) | 1995-10-19 |
| JPH02170050A (ja) | 1990-06-29 |
| CA2001696A1 (en) | 1990-04-28 |
| EP0371253A3 (en) | 1990-06-20 |
| AU634985B2 (en) | 1993-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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