DE69920734D1 - VERFAHREN UND ZUSAMMENSETZUNGEN ZUR PRÄVENTION von TOLERANZ VON BRONCHODILATOREN - Google Patents

VERFAHREN UND ZUSAMMENSETZUNGEN ZUR PRÄVENTION von TOLERANZ VON BRONCHODILATOREN

Info

Publication number: DE69920734D1
Authority: DE; Germany
Prior art keywords: bronchodilators; compositions; preventing tolerance; tolerance; preventing
Prior art date: 1998-10-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69920734T

Other languages

English (en)

Other versions

DE69920734T2 (de

Inventor

Tahir Ahmed

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ivax Research Holdings Inc

Original Assignee

Ivax Research Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-30

Filing date

1999-10-13

Publication date

2004-11-04

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26803748&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69920734(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-10-13 Application filed by Ivax Research Inc filed Critical Ivax Research Inc

2004-11-04 Application granted granted Critical

2004-11-04 Publication of DE69920734D1 publication Critical patent/DE69920734D1/de

2005-10-06 Publication of DE69920734T2 publication Critical patent/DE69920734T2/de

2019-10-14 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pulmonology (AREA)
Emergency Medicine (AREA)
Engineering & Computer Science (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Investigating Or Analysing Biological Materials (AREA)

DE69920734T 1998-10-30 1999-10-13 Verfahren und zusammensetzungen zur vorbeugung von toleranz gegenüber bronchodilatoren Expired - Lifetime DE69920734T2 (de)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US10650798P	1998-10-30	1998-10-30
US106507P		1998-10-30
US362540		1999-07-28
US09/362,540 US6235725B1 (en)	1998-10-30	1999-07-28	Methods and compositions for the prevention of tolerance to medications
PCT/US1999/024034 WO2000025723A2 (en)	1998-10-30	1999-10-13	Methods and compositions for the prevention of tolerance to medications

Publications (2)

Publication Number	Publication Date
DE69920734D1 true DE69920734D1 (de)	2004-11-04
DE69920734T2 DE69920734T2 (de)	2005-10-06

Family

ID=26803748

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69920734T Expired - Lifetime DE69920734T2 (de)	1998-10-30	1999-10-13	Verfahren und zusammensetzungen zur vorbeugung von toleranz gegenüber bronchodilatoren

Country Status (25)

Country	Link
US (1)	US6235725B1 (de)
EP (1)	EP1124563B1 (de)
JP (1)	JP4585121B2 (de)
CN (2)	CN1329496A (de)
AR (2)	AR023911A1 (de)
AT (1)	ATE277621T1 (de)
AU (1)	AU760119B2 (de)
BR (1)	BR9915818A (de)
CA (1)	CA2348926C (de)
CO (1)	CO5160320A1 (de)
CY (1)	CY1107493T1 (de)
CZ (1)	CZ297914B6 (de)
DE (1)	DE69920734T2 (de)
ES (1)	ES2228173T3 (de)
HK (1)	HK1041596A1 (de)
HU (1)	HUP0302492A3 (de)
IL (2)	IL142865A0 (de)
IS (1)	IS2321B (de)
NO (1)	NO333194B1 (de)
NZ (1)	NZ511399A (de)
PL (1)	PL195592B1 (de)
PT (1)	PT1124563E (de)
SK (1)	SK285150B6 (de)
TW (1)	TW565451B (de)
WO (1)	WO2000025723A2 (de)

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US9006175B2 (en)	1999-06-29	2015-04-14	Mannkind Corporation	Potentiation of glucose elimination
CA2395653C (en) *	2000-10-12	2006-05-09	Boehringer Ingelheim Pharma Kg	New inhalable powder containing tiotropium
US20030055026A1 (en)	2001-04-17	2003-03-20	Dey L.P.	Formoterol/steroid bronchodilating compositions and methods of use thereof
US6667344B2 (en) *	2001-04-17	2003-12-23	Dey, L.P.	Bronchodilating compositions and methods
US20030070679A1 (en) *	2001-06-01	2003-04-17	Boehringer Ingelheim Pharma Kg	Capsules containing inhalable tiotropium
US6702997B2 (en)	2001-10-26	2004-03-09	Dey, L.P.	Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
JP2003221335A (ja)	2001-10-26	2003-08-05	Dey Lp	慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
US20030140920A1 (en) *	2001-10-26	2003-07-31	Dey L.P.	Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
US20030191151A1 (en) *	2001-10-26	2003-10-09	Imtiaz Chaudry	Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20030203930A1 (en) *	2001-10-26	2003-10-30	Imtiaz Chaudry	Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
CA2516322C (en) *	2002-02-18	2013-10-15	University Of Southampton	Glycosaminoglycan-dnase combination therapy
WO2003068188A1 (en) *	2002-02-18	2003-08-21	University Of Southampton	Combination therapy for respiratory disorders
DE60323973D1 (de) *	2002-02-18	2008-11-20	Univ Southampton	Verwendung von glykosaminglykanen wie z.b. heparin zur behandlung von atemerkrankungen wie copd
ES2425392T3 (es)	2002-03-20	2013-10-15	Mannkind Corporation	Cartucho para un aparato de inhalación
EP1551852A4 (de) *	2002-04-25	2007-03-21	Momenta Pharmaceuticals Inc	Verfahren und produkte zur verabreichung an die schleimhaut
US20040023935A1 (en) *	2002-08-02	2004-02-05	Dey, L.P.	Inhalation compositions, methods of use thereof, and process for preparation of same
EP2322243A1 (de) *	2002-08-29	2011-05-18	Cipla Ltd.	Pharmazeutische Produkte und Zusammensetzungen enthaltend Formoterol, Ciclesonid und Tiotropium
US7763280B2 (en) *	2002-11-28	2010-07-27	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Tiotropium containing powder formulation for inhalation
US20040109826A1 (en) *	2002-12-06	2004-06-10	Dey, L.P.	Stabilized albuterol compositions and method of preparation thereof
JP4851185B2 (ja)	2003-05-16	2012-01-11	ジェレックスインターナショナル株式会社	アレルギー症状抑制剤及び空気濾過フィルター
TWI359675B (en) *	2003-07-10	2012-03-11	Dey L P	Bronchodilating β-agonist compositions
US20050043343A1 (en) *	2003-07-28	2005-02-24	Boehringer Ingelheim International Gmbh	Medicaments for inhalation comprising an anticholinergic and a PDE IV inhibitor
DK1786784T3 (da)	2004-08-20	2011-02-14	Mannkind Corp	Katalyse af diketopiperazinsyntese
BR122019022692B1 (pt)	2004-08-23	2023-01-10	Mannkind Corporation	Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
WO2007033372A2 (en)	2005-09-14	2007-03-22	Mannkind Corporation	Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
DK1986679T3 (da)	2006-02-22	2017-11-20	Mannkind Corp	Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof
US8485180B2 (en)	2008-06-13	2013-07-16	Mannkind Corporation	Dry powder drug delivery system
CA3153292A1 (en)	2008-06-13	2009-12-17	Mannkind Corporation	A dry powder inhaler and system for drug delivery
CN102065942B (zh)	2008-06-20	2013-12-11	曼金德公司	用于对吸入工作进行实时描绘的交互式设备和方法
TWI532497B (zh)	2008-08-11	2016-05-11	曼凱公司	超快起作用胰島素之用途
US8314106B2 (en)	2008-12-29	2012-11-20	Mannkind Corporation	Substituted diketopiperazine analogs for use as drug delivery agents
PL2405963T3 (pl)	2009-03-11	2014-04-30	Mannkind Corp	Urządzenie, układ i sposób pomiaru oporu inhalatora
KR20180036807A (ko)	2009-06-12	2018-04-09	맨카인드 코포레이션	한정된 비표면적을 갖는 디케토피페라진 마이크로입자
CA2778698A1 (en)	2009-11-03	2011-05-12	Mannkind Corporation	An apparatus and method for simulating inhalation efforts
WO2011133687A2 (en) *	2010-04-20	2011-10-27	President And Fellows Of Harvard College	Methods and compositions for inhibition of beta2-adrenergic receptor degradation
RU2571331C1 (ru)	2010-06-21	2015-12-20	Маннкайнд Корпорейшн	Системы и способы доставки сухих порошковых лекарств
KR101940832B1 (ko)	2011-04-01	2019-01-21	맨카인드 코포레이션	의약 카트리지용 블리스터 패키지
WO2012174472A1 (en)	2011-06-17	2012-12-20	Mannkind Corporation	High capacity diketopiperazine microparticles
EP2776053A1 (de)	2011-10-24	2014-09-17	MannKind Corporation	Verfahren und zusammensetzungen zur schmerzbehandlung
CN104619369B (zh)	2012-07-12	2018-01-30	曼金德公司	干粉药物输送系统和方法
EP2911690A1 (de)	2012-10-26	2015-09-02	MannKind Corporation	Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
AU2014228415B2 (en)	2013-03-15	2018-08-09	Mannkind Corporation	Microcrystalline diketopiperazine compositions and methods
CA2918369C (en)	2013-07-18	2021-06-29	Mannkind Corporation	Heat-stable dry powder pharmaceutical compositions and methods
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1999
- 1999-07-28 US US09/362,540 patent/US6235725B1/en not_active Expired - Lifetime
- 1999-10-13 HK HK02103273.0A patent/HK1041596A1/zh unknown
- 1999-10-13 IL IL14286599A patent/IL142865A0/xx active IP Right Grant
- 1999-10-13 CZ CZ20011518A patent/CZ297914B6/cs not_active IP Right Cessation
- 1999-10-13 PL PL99364727A patent/PL195592B1/pl unknown
- 1999-10-13 SK SK590-2001A patent/SK285150B6/sk not_active IP Right Cessation
- 1999-10-13 EP EP99971300A patent/EP1124563B1/de not_active Expired - Lifetime
- 1999-10-13 DE DE69920734T patent/DE69920734T2/de not_active Expired - Lifetime
- 1999-10-13 AT AT99971300T patent/ATE277621T1/de active
- 1999-10-13 WO PCT/US1999/024034 patent/WO2000025723A2/en not_active Ceased
- 1999-10-13 NZ NZ511399A patent/NZ511399A/en not_active IP Right Cessation
- 1999-10-13 ES ES99971300T patent/ES2228173T3/es not_active Expired - Lifetime
- 1999-10-13 JP JP2000579168A patent/JP4585121B2/ja not_active Expired - Fee Related
- 1999-10-13 BR BR9915818-3A patent/BR9915818A/pt not_active Application Discontinuation
- 1999-10-13 CA CA2348926A patent/CA2348926C/en not_active Expired - Fee Related
- 1999-10-13 HU HU0302492A patent/HUP0302492A3/hu not_active Application Discontinuation
- 1999-10-13 PT PT99971300T patent/PT1124563E/pt unknown
- 1999-10-13 CN CN99813923A patent/CN1329496A/zh active Pending
- 1999-10-13 CN CNB2004100629128A patent/CN100352448C/zh not_active Expired - Fee Related
- 1999-10-13 AU AU12051/00A patent/AU760119B2/en not_active Ceased
- 1999-10-28 AR ARP990105443A patent/AR023911A1/es not_active Application Discontinuation
- 1999-10-29 CO CO99068642A patent/CO5160320A1/es unknown
- 1999-11-09 TW TW088118719A patent/TW565451B/zh not_active IP Right Cessation
2001
- 2001-04-27 NO NO20012097A patent/NO333194B1/no not_active IP Right Cessation
- 2001-04-27 IS IS5928A patent/IS2321B/is unknown
- 2001-04-30 IL IL142865A patent/IL142865A/en not_active IP Right Cessation
2004
- 2004-12-06 CY CY20041101437T patent/CY1107493T1/el unknown
2011
- 2011-09-07 AR ARP110103258A patent/AR082913A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU1205100A (en)	2000-05-22
PL364727A1 (en)	2004-12-13
EP1124563B1 (de)	2004-09-29
HUP0302492A2 (hu)	2003-11-28
CZ297914B6 (cs)	2007-04-25
NO20012097D0 (no)	2001-04-27
DE69920734T2 (de)	2005-10-06
CO5160320A1 (es)	2002-05-30
IS5928A (is)	2001-04-27
HUP0302492A3 (en)	2005-05-30
TW565451B (en)	2003-12-11
AU760119B2 (en)	2003-05-08
WO2000025723A2 (en)	2000-05-11
SK285150B6 (sk)	2006-07-07
AR023911A1 (es)	2002-09-04
AR082913A2 (es)	2013-01-16
NZ511399A (en)	2004-09-24
EP1124563A2 (de)	2001-08-22
HK1041596A1 (zh)	2002-07-12
PL195592B1 (pl)	2007-10-31
NO333194B1 (no)	2013-04-02
IL142865A (en)	2006-07-05
IL142865A0 (en)	2002-03-10
JP4585121B2 (ja)	2010-11-24
NO20012097L (no)	2001-06-15
JP2002535245A (ja)	2002-10-22
CN1572303A (zh)	2005-02-02
CY1107493T1 (el)	2013-03-13
CN1329496A (zh)	2002-01-02
ES2228173T3 (es)	2005-04-01
CA2348926A1 (en)	2000-05-11
ATE277621T1 (de)	2004-10-15
CN100352448C (zh)	2007-12-05
EP1124563A4 (de)	2002-01-02
US6235725B1 (en)	2001-05-22
BR9915818A (pt)	2002-06-18
SK5902001A3 (en)	2002-07-02
PT1124563E (pt)	2005-01-31
WO2000025723A3 (en)	2000-07-27
IS2321B (is)	2007-12-15
CA2348926C (en)	2011-08-23
CZ20011518A3 (cs)	2002-04-17

Publication	Publication Date	Title
DE69920734D1 (de)	2004-11-04	VERFAHREN UND ZUSAMMENSETZUNGEN ZUR PRÄVENTION von TOLERANZ VON BRONCHODILATOREN
DE69812232D1 (de)	2003-04-24	Beschichtungszusammensetzung und Verfahren zur Beschichtung
ATE233049T1 (de)	2003-03-15	Zusammensetzung und verfahren zur kontrolle von schädlichen bio-organismen
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