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DE69919769D1 - 3,6-Ketal-Makrolidantibiotika - Google Patents

3,6-Ketal-Makrolidantibiotika

Info

Publication number
DE69919769D1
DE69919769D1 DE69919769T DE69919769T DE69919769D1 DE 69919769 D1 DE69919769 D1 DE 69919769D1 DE 69919769 T DE69919769 T DE 69919769T DE 69919769 T DE69919769 T DE 69919769T DE 69919769 D1 DE69919769 D1 DE 69919769D1
Authority
DE
Germany
Prior art keywords
ketal
macrolide antibiotics
macrolide
antibiotics
ketal macrolide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69919769T
Other languages
English (en)
Other versions
DE69919769T2 (de
Inventor
Kristin M Lundy
Hengmiao Cheng
Subas M Sakya
Peter Bertinato
Martha L Minich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Application granted granted Critical
Publication of DE69919769D1 publication Critical patent/DE69919769D1/de
Publication of DE69919769T2 publication Critical patent/DE69919769T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE69919769T 1998-03-03 1999-02-23 3,6-Ketal-Makrolidantibiotika Expired - Fee Related DE69919769T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7663098P 1998-03-03 1998-03-03
US76630P 1998-03-03

Publications (2)

Publication Number Publication Date
DE69919769D1 true DE69919769D1 (de) 2004-10-07
DE69919769T2 DE69919769T2 (de) 2005-01-27

Family

ID=22133253

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69919769T Expired - Fee Related DE69919769T2 (de) 1998-03-03 1999-02-23 3,6-Ketal-Makrolidantibiotika

Country Status (17)

Country Link
US (1) US6043226A (de)
EP (1) EP0941998B1 (de)
JP (1) JP3666788B2 (de)
CN (1) CN1244532A (de)
AR (1) AR016715A1 (de)
AT (1) ATE275151T1 (de)
AU (1) AU741435B2 (de)
BR (1) BR9900856A (de)
CA (1) CA2263203C (de)
DE (1) DE69919769T2 (de)
DK (1) DK0941998T3 (de)
ES (1) ES2226282T3 (de)
HU (1) HUP9900492A3 (de)
NO (1) NO312366B1 (de)
NZ (1) NZ334442A (de)
PT (1) PT941998E (de)
ZA (1) ZA991664B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
TR200200435T2 (tr) * 1998-11-03 2002-07-22 Pfizer Products Inc. Yeni makrolit antibiyotikler.
US6514944B2 (en) * 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6451768B1 (en) * 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
NZ515027A (en) 1999-04-16 2004-01-30 Kosan Biosciences Inc Erythromycin derivatives as antibiotics
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
US6590083B1 (en) * 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
OA11945A (en) * 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
EP1146051A3 (de) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A-Derivate
JP2005502302A (ja) * 2000-11-07 2005-01-27 モーフオテク・インコーポレーテツド 超変異性哺乳動物細胞より新規抗微生物剤を単離するための方法
US8063021B2 (en) * 2002-01-17 2011-11-22 Kosan Biosciences Incorporated Ketolide anti-infective compounds
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
ITMI20022292A1 (it) * 2002-10-29 2004-04-30 Zambon Spa 9a-azalidi ad attivita' antiinfiammatoria.
US20060141470A1 (en) * 2003-02-14 2006-06-29 Kalayoglu Murat V Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof
MX2007007598A (es) * 2004-12-21 2007-07-25 Pfizer Prod Inc Macrolidos.
US7517859B2 (en) * 2005-05-04 2009-04-14 Enanta Pharmaceuticals, Inc. Spirocyclic bicyclolides
EP2203435B1 (de) * 2007-09-17 2018-07-18 Enanta Pharmaceuticals, Inc. 6, 11-gebrückte biaryl-makrolide
WO2018193116A1 (en) * 2017-04-20 2018-10-25 Novintum Biotechnology Gmbh Azithromycin derivatives containing a phosphonium ion as anticancer agents
WO2018193111A1 (en) * 2017-04-20 2018-10-25 Novintum Biotechnology Gmbh Azithromycin derivatives containing a phosphonium ion as anticancer agents
WO2018193126A1 (en) * 2017-04-20 2018-10-25 Novintum Biotechnology Gmbh Azithromycin derivatives containing a phosphonium ion as antibacterial agents
WO2018193117A1 (en) * 2017-04-20 2018-10-25 Novintum Biotechnology Gmbh Azithromycin derivatives containing a phosphonium ion as anticancer agents
JP2020517749A (ja) * 2017-04-20 2020-06-18 ライジング タイド ファウンデーション 抗がん剤としてホスホニウムイオンを含むアジスロマイシン誘導体
GB201706299D0 (en) * 2017-04-20 2017-06-07 Novintum Biotechnology Gmbh Compounds
EP3612177A4 (de) 2017-04-21 2021-01-13 Lunella Biotech, Inc. Targeting von hypoxischen krebsstammzellen (cscs) mit doxycyclin: implikationen zur verbesserung der anti-angiogenesetherapie
WO2018195434A1 (en) 2017-04-21 2018-10-25 Lisanti Michael P Vitamin c and doxycycline: a synthetic lethal combination therapy for eradicating cancer stem cells (cscs)
CA3063717C (en) 2017-05-19 2021-08-24 Lunella Biotech, Inc. Antimitoscins: targeted inhibitors of mitochondrial biogenesis for eradicating cancer stem cells
EP3624897A4 (de) 2017-05-19 2021-07-14 Lunella Biotech, Inc. Begleitdiagnostika für mitochondrien-hemmer
CR20200033A (es) 2017-06-26 2020-03-05 Lunella Biotech Inc Mitocetoscinas: agentes terapéuticos basados en mitocondrias que fijan como objetivo el metabolismo de cetonas en células cancerosas
GB201817083D0 (en) * 2018-10-19 2018-12-05 Novintum Biotechnology Gmbh Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8721165D0 (en) * 1987-09-09 1987-10-14 Beecham Group Plc Chemical compounds
EP0344106A3 (de) * 1988-05-24 1990-01-31 Ciba-Geigy Ag Blaue Dispersionsfarbstoffe und Mischungen blauer Dispersionsfarbstoffe
US5302705A (en) * 1989-10-07 1994-04-12 Taisho Pharmaceutical Co., Ltd. 6-O-methylerythromycin a oxime derivatives
US5602239A (en) * 1993-01-26 1997-02-11 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
JP2000509712A (ja) * 1996-05-07 2000-08-02 アボツト・ラボラトリーズ ６―ｏ―置換エリスロマイシン及びその製造方法

Also Published As

Publication number Publication date
US6043226A (en) 2000-03-28
ATE275151T1 (de) 2004-09-15
PT941998E (pt) 2004-12-31
CN1244532A (zh) 2000-02-16
DE69919769T2 (de) 2005-01-27
NO991012D0 (no) 1999-03-02
BR9900856A (pt) 2000-04-25
EP0941998B1 (de) 2004-09-01
HU9900492D0 (en) 1999-04-28
HUP9900492A2 (hu) 1999-09-28
JP3666788B2 (ja) 2005-06-29
NO312366B1 (no) 2002-04-29
AR016715A1 (es) 2001-07-25
CA2263203C (en) 2002-09-03
DK0941998T3 (da) 2004-09-20
CA2263203A1 (en) 1999-09-03
HUP9900492A3 (en) 2001-08-28
JPH11315093A (ja) 1999-11-16
AU741435B2 (en) 2001-11-29
NO991012L (no) 1999-09-06
AU1856299A (en) 1999-09-16
EP0941998A2 (de) 1999-09-15
ES2226282T3 (es) 2005-03-16
ZA991664B (en) 2000-10-12
NZ334442A (en) 2000-03-27
EP0941998A3 (de) 1999-10-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee