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DE69907926D1 - 1,2,4-triazol-3-thion verbindungen - Google Patents

1,2,4-triazol-3-thion verbindungen

Info

Publication number
DE69907926D1
DE69907926D1 DE69907926T DE69907926T DE69907926D1 DE 69907926 D1 DE69907926 D1 DE 69907926D1 DE 69907926 T DE69907926 T DE 69907926T DE 69907926 T DE69907926 T DE 69907926T DE 69907926 D1 DE69907926 D1 DE 69907926D1
Authority
DE
Germany
Prior art keywords
triazol
thion compounds
compounds
thion
triazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69907926T
Other languages
English (en)
Other versions
DE69907926T2 (de
Inventor
Andrew Baxter
Colin Bennion
Peter Cage
Nicholas Kindon
Michael Mortimore
Bryan Roberts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of DE69907926D1 publication Critical patent/DE69907926D1/de
Application granted granted Critical
Publication of DE69907926T2 publication Critical patent/DE69907926T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE69907926T 1998-09-01 1999-08-27 1,2,4-triazol-3-thion verbindungen Expired - Fee Related DE69907926T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9802937 1998-09-01
SE9802937A SE9802937D0 (sv) 1998-09-01 1998-09-01 Novel compounds
PCT/SE1999/001469 WO2000012489A1 (en) 1998-09-01 1999-08-27 1, 2, 4-triazole-3-thione compounds

Publications (2)

Publication Number Publication Date
DE69907926D1 true DE69907926D1 (de) 2003-06-18
DE69907926T2 DE69907926T2 (de) 2004-02-19

Family

ID=20412435

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69907926T Expired - Fee Related DE69907926T2 (de) 1998-09-01 1999-08-27 1,2,4-triazol-3-thion verbindungen

Country Status (8)

Country Link
US (1) US20020086862A1 (de)
EP (1) EP1109790B1 (de)
JP (1) JP2002525281A (de)
AT (1) ATE240303T1 (de)
AU (1) AU5892399A (de)
DE (1) DE69907926T2 (de)
SE (1) SE9802937D0 (de)
WO (1) WO2000012489A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2361003A (en) * 2000-04-07 2001-10-10 Astrazeneca Ab Novel compounds
PL365886A1 (en) * 2000-07-18 2005-01-10 Smithkline Beecham Corporation Use of il-8 receptor antagonists in the treatment of virus infections
AU2003215549A1 (en) 2003-02-03 2004-08-30 Janssen Pharmaceutica N.V. Mercaptoimidazoles as ccr2 receptor antagonists
US7276050B2 (en) * 2004-03-02 2007-10-02 Alan Franklin Trans-scleral drug delivery method and apparatus
WO2005097112A2 (en) * 2004-03-08 2005-10-20 Wyeth Ion channel modulators
EP1778646A1 (de) * 2004-08-11 2007-05-02 Janssen Pharmaceutica N.V. Mercaptoimidazole als ccr2-rezeptor-antagonisten
FR2883875A1 (fr) * 2005-04-01 2006-10-06 Galderma Res & Dev Nouveaux inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
WO2006103119A2 (en) * 2005-04-01 2006-10-05 Galderma Research & Development Tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and also in cosmetics
WO2009077500A2 (de) * 2007-12-19 2009-06-25 Basf Se Azolylmethyloxirane, ihre verwendung sowie sie enthaltende mittel
WO2009077471A2 (de) * 2007-12-19 2009-06-25 Basf Se Azolylmethyloxirane, ihre verwendung sowie sie enthaltende mittel
BRPI0821296A2 (pt) * 2007-12-19 2014-10-07 Basf Se Composto, uso de um composto, composição, semente, método para controlar fungos fitopatogênicos, medicamento, e, processos para preparar um antimicótico e compostos
TWI487705B (zh) 2009-12-17 2015-06-11 Lundbeck & Co As H 作為pde10a酵素抑制劑之雜芳香族芳基三唑衍生物
WO2013134562A1 (en) 2012-03-09 2013-09-12 Inception 2, Inc. Triazolone compounds and uses thereof
JP6404230B2 (ja) 2012-12-20 2018-10-10 インセプション 2、 インコーポレイテッド トリアゾロン化合物およびその使用
CN103012233B (zh) * 2012-12-26 2015-08-26 华润赛科药业有限责任公司 一种n-(氨基硫代甲基)-5-氧代-1-丙基-2-吡咯烷乙酰胺的制备方法
EA201690230A1 (ru) 2013-09-06 2016-07-29 Инсепшн 2, Инк. Соединения триазолона и их применения
AU2024260234A1 (en) * 2023-04-26 2025-11-13 Institució Catalana De Recerca I Estudis Avançats 1,2,4-triazole-3-thione inhibitors of trex2 for use in the treatment of psoriasis, atopic dermatitis or ichthyosis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW467902B (en) * 1996-07-31 2001-12-11 Bristol Myers Squibb Co Diphenyl heterocycles as potassium channel modulators

Also Published As

Publication number Publication date
EP1109790A1 (de) 2001-06-27
AU5892399A (en) 2000-03-21
JP2002525281A (ja) 2002-08-13
WO2000012489A1 (en) 2000-03-09
EP1109790B1 (de) 2003-05-14
ATE240303T1 (de) 2003-05-15
US20020086862A1 (en) 2002-07-04
SE9802937D0 (sv) 1998-09-01
DE69907926T2 (de) 2004-02-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee