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DE69837664D1 - Wässrige suspensionspräparationen mit exzellenter redispersibilität - Google Patents

Wässrige suspensionspräparationen mit exzellenter redispersibilität

Info

Publication number
DE69837664D1
DE69837664D1 DE69837664T DE69837664T DE69837664D1 DE 69837664 D1 DE69837664 D1 DE 69837664D1 DE 69837664 T DE69837664 T DE 69837664T DE 69837664 T DE69837664 T DE 69837664T DE 69837664 D1 DE69837664 D1 DE 69837664D1
Authority
DE
Germany
Prior art keywords
aqueous suspension
suspension preparations
excellent redispersibility
redispersibility
preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69837664T
Other languages
English (en)
Other versions
DE69837664T2 (de
Inventor
Shin-Ichi Yasueda
Keiichi Matsuhisa
Hideo Terayama
Katsuhiro Inada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Publication of DE69837664D1 publication Critical patent/DE69837664D1/de
Application granted granted Critical
Publication of DE69837664T2 publication Critical patent/DE69837664T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69837664T 1997-05-14 1998-04-30 Wässrige suspensionspräparationen mit exzellenter redispersibilität Expired - Lifetime DE69837664T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP12416697 1997-05-14
JP12416697 1997-05-14
PCT/JP1998/001998 WO1998051281A1 (en) 1997-05-14 1998-04-30 Aqueous suspension preparations with excellent redispersibility

Publications (2)

Publication Number Publication Date
DE69837664D1 true DE69837664D1 (de) 2007-06-06
DE69837664T2 DE69837664T2 (de) 2008-01-03

Family

ID=14878589

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69837664T Expired - Lifetime DE69837664T2 (de) 1997-05-14 1998-04-30 Wässrige suspensionspräparationen mit exzellenter redispersibilität

Country Status (7)

Country Link
US (3) US6274634B1 (de)
EP (1) EP0995435B1 (de)
KR (1) KR20010012188A (de)
CA (1) CA2289618A1 (de)
DE (1) DE69837664T2 (de)
ES (1) ES2284202T3 (de)
WO (1) WO1998051281A1 (de)

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CA2289618A1 (en) * 1997-05-14 1998-11-19 Shin-Ichi Yasueda Aqueous suspension preparations with excellent redispersibility
HRP20010309B1 (en) 1998-12-23 2005-06-30 Idea Ag Improved formulation for topical non-invasive application in vivo
DE69901377T2 (de) 1999-01-27 2003-01-02 Idea Ag Nichtinvasive Impfung durch die Haut
ATE216223T1 (de) 1999-01-27 2002-05-15 Idea Ag Transnasaler transport bzw. impfung mit hochadaptierbaren trägern
WO2001001962A1 (en) 1999-07-05 2001-01-11 Idea Ag. A method for the improvement of transport across adaptable semi-permeable barriers
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
EP1282401A2 (de) * 2000-05-15 2003-02-12 PHARMACIA & UPJOHN S.p.A. Stabilisierte steroidale suspension
AU2001278779A1 (en) * 2000-08-25 2002-03-04 Senju Pharmaceutical Co. Ltd. Aqueous suspension preparations
AU2001290328A1 (en) * 2000-09-29 2002-04-08 Wakamoto Pharmaceutical Co., Ltd. Eye drops comprising acyclovir suspension
US20040058956A1 (en) * 2000-12-11 2004-03-25 Yohko Akiyama Pharmaceutical composition having an improved water solubility
FI112282B (fi) * 2001-01-12 2003-11-14 Kibron Inc Oy Menetelmä vesipitoisen liuoksen pintajännityksen mittaamiseksi
JP3805203B2 (ja) * 2001-02-16 2006-08-02 日本油脂株式会社 点眼用水性懸濁製剤およびその製造方法
MXPA03009021A (es) 2001-04-03 2004-02-12 Schering Corp Composicion antifungal con biodisponibilidad aumentada.
US20030055026A1 (en) * 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US20040023935A1 (en) * 2002-08-02 2004-02-05 Dey, L.P. Inhalation compositions, methods of use thereof, and process for preparation of same
US7473432B2 (en) * 2002-10-11 2009-01-06 Idea Ag NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery
US20040109826A1 (en) * 2002-12-06 2004-06-10 Dey, L.P. Stabilized albuterol compositions and method of preparation thereof
JP4430616B2 (ja) * 2003-02-20 2010-03-10 千寿製薬株式会社 水性懸濁液剤
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
MXPA06003185A (es) * 2003-09-23 2006-06-23 Alcon Inc Formulaciones de acetonuro de triamcinolona y de acetato de anecotarve para inyeccion.
US20050136116A1 (en) * 2003-12-18 2005-06-23 Keith Whitehead Stabilized prednisolone sodium phosphate solutions
CA2581126A1 (en) * 2004-09-24 2006-04-06 Rfe Pharma Llc Carboxy-amido-triazoles for the localized treatment of ocular diseases
KR20070086045A (ko) * 2004-11-12 2007-08-27 이데아 아게 피부 상태 치료에서의 확대된 표면 집합체
TWI363626B (en) 2004-11-15 2012-05-11 Otsuka Pharma Co Ltd Aqueous ophthalmic suspension of crystalline rebamipide
EP1904028A1 (de) * 2005-06-16 2008-04-02 Warner Chilcott Company Inc. Östrogenzusammensetzungen zur vaginalen verabreichung
US20070004693A1 (en) * 2005-06-16 2007-01-04 Warner Chilcott Company Inc. Estrogen compositions for vaginal administration
CN101232869B (zh) * 2005-06-16 2016-03-02 沃纳奇尔科特有限责任公司 局部给药的凝胶组合物
US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
US7597333B2 (en) * 2006-04-05 2009-10-06 Acorn Products, Llc Brake assembly and scooters and skateboards including the same
TWI415629B (zh) * 2006-10-26 2013-11-21 Otsuka Pharma Co Ltd 含有瑞巴匹特之水性醫藥懸浮物及其製造方法
KR101475965B1 (ko) * 2007-03-29 2014-12-23 산텐 세이야꾸 가부시키가이샤 플루오로메토론을 함유하는 현탁형 점안제
US8300252B2 (en) * 2008-06-18 2012-10-30 Livescribe, Inc. Managing objects with varying and repeated printed positioning information
EP2366408B1 (de) * 2010-03-01 2012-07-18 Laboratorios SALVAT, S.A. Wässrige klare Lösungen aus Fluocinolon-Acetonid zur Behandlung von Ohrentzündungen
AR090775A1 (es) 2012-04-23 2014-12-03 Otsuka Pharma Co Ltd Preparado inyectable
ES2727474T3 (es) * 2012-05-08 2019-10-16 Nicox Ophthalmics Inc Nanocristales de propionato de fluticasona
US9308165B2 (en) * 2013-08-22 2016-04-12 Therapeutic Vision, Inc. Composition for treating ocular effects of diabetes
AU2014313287B2 (en) 2013-08-30 2019-05-23 Nof Corporation Ophthalmic solution
EP3954362A1 (de) 2014-07-28 2022-02-16 Sun Pharma Advanced Research Company Ltd Verfahren zur erhöhung der bioverfügbarkeit und/oder zur verlängerung der ophthalmischen wirkung eines arzneimittels
TWI773641B (zh) 2015-05-08 2022-08-11 日商活效製藥股份有限公司 含有糖皮質類固醇（ｇｌｕｃｏｃｏｒｔｉｃｏｉｄｓ）之奈米微粒子之水性懸浮液劑
WO2018033792A2 (en) 2016-08-19 2018-02-22 Orasis Pharmaceuticals Ltd. Ophthalmic pharmaceutical compositions and uses relating thereto
MX2023011649A (es) * 2021-03-30 2023-10-11 Senju Pharma Co Suspension que contiene derivado de heterociclidenacetamida.

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JPS5296721A (en) * 1976-02-10 1977-08-13 Nippon Kayaku Co Ltd Stable pharmaceutical dispersion
DE3013839A1 (de) * 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
JPS57171912A (en) * 1981-04-14 1982-10-22 Sumitomo Chem Co Ltd Cream
JPS60161915A (ja) 1984-02-01 1985-08-23 Sato Seiyaku Kk 制酸剤含有内用液剤
US5124392A (en) * 1988-10-03 1992-06-23 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
CS275231B2 (en) * 1989-09-29 1992-02-19 Ustav Makormolekularni Chemie Medicine bottle
JPH03135924A (ja) 1989-10-23 1991-06-10 Takada Seiyaku Kk 新規な消炎作用物質含有外用製剤
JP2554784B2 (ja) 1991-03-15 1996-11-13 杏林製薬株式会社 懸濁シロップ剤
EP0531529B1 (de) * 1991-03-27 1996-11-20 Senju Pharmaceutical Co., Ltd. Verfahren zur herstellung einer wässrigen suspension
JP2808378B2 (ja) * 1991-03-27 1998-10-08 武田薬品工業株式会社 水性懸濁液剤の製造法
ES2079994B1 (es) * 1992-10-07 1996-08-01 Cusi Lab Formulacion farmaceutica a base de polimixina-trimetoprim y un agente antiinflamatorio para su utilizacion topica oftalmica y otica.
AU668447B2 (en) * 1993-04-16 1996-05-02 Wakamoto Pharmaceutical Co., Ltd. Reversible, thermally gelling water-base medicinal composition
EP0709099A3 (de) 1994-09-28 1996-07-24 Senju Pharma Co Wässrige Suspension zur nasalen Verabreichung enthaltend Cyclodextrin
JPH08151332A (ja) 1994-09-28 1996-06-11 Senju Pharmaceut Co Ltd 点鼻用水性懸濁液
US5516808A (en) * 1994-10-27 1996-05-14 Sawaya; Assad S. Topical cellulose pharmaceutical formulation
JP3135924B2 (ja) 1995-01-05 2001-02-19 タイテックス アクティーゼルスカブ ヒッププロテクタ付きズボン
JP3269770B2 (ja) 1995-03-02 2002-04-02 参天製薬株式会社 再分散性の優れたイオン性高分子配合水性懸濁点眼剤
US5683993A (en) * 1995-06-22 1997-11-04 Ciba Vision Corporation Compositions and methods for stabilizing polymers
US5811446A (en) * 1997-04-18 1998-09-22 Cytos Pharmaceuticals Llc Prophylactic and therapeutic methods for ocular degenerative diseases and inflammations and histidine compositions therefor
CA2289618A1 (en) * 1997-05-14 1998-11-19 Shin-Ichi Yasueda Aqueous suspension preparations with excellent redispersibility
WO1999037286A1 (en) 1998-01-22 1999-07-29 Santen Pharmaceutical Co., Ltd. Fluorometholone suspension eye drops

Also Published As

Publication number Publication date
US6683070B2 (en) 2004-01-27
US6448296B2 (en) 2002-09-10
US20010036966A1 (en) 2001-11-01
EP0995435B1 (de) 2007-04-25
WO1998051281A1 (en) 1998-11-19
DE69837664T2 (de) 2008-01-03
ES2284202T3 (es) 2007-11-01
US6274634B1 (en) 2001-08-14
US20030008010A1 (en) 2003-01-09
EP0995435A1 (de) 2000-04-26
KR20010012188A (ko) 2001-02-15
EP0995435A4 (de) 2004-11-10
CA2289618A1 (en) 1998-11-19

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Legal Events

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8364 No opposition during term of opposition