DE69710729D1 - Fungizide zusammensetzung mit erhörter bioverfügbarkeit - Google Patents

Fungizide zusammensetzung mit erhörter bioverfügbarkeit

Info

Publication number: DE69710729D1
Authority: DE; Germany
Prior art keywords: heared; bioavailability; fungicidal composition; fungicidal; composition
Prior art date: 1996-05-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69710729T

Other languages

English (en)

Other versions

DE69710729T2 (de

Inventor

A Sangekar

A Vadino

I Lee

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck Sharp and Dohme LLC

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-24

Filing date

1997-05-21

Publication date

2002-04-04

1997-05-21 Application filed by Schering Corp filed Critical Schering Corp

2002-04-04 Publication of DE69710729D1 publication Critical patent/DE69710729D1/de

2002-08-14 Application granted granted Critical

2002-08-14 Publication of DE69710729T2 publication Critical patent/DE69710729T2/de

2017-05-22 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DE69710729T 1996-05-24 1997-05-21 Fungizide zusammensetzung mit erhörter bioverfügbarkeit Expired - Lifetime DE69710729T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US65532996A	1996-05-24	1996-05-24
PCT/US1997/019388 WO1998007429A2 (en)	1996-05-24	1997-05-21	Antifungal composition with enhanced bioavailability

Publications (2)

Publication Number	Publication Date
DE69710729D1 true DE69710729D1 (de)	2002-04-04
DE69710729T2 DE69710729T2 (de)	2002-08-14

Family

ID=24628452

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69710729T Expired - Lifetime DE69710729T2 (de)	1996-05-24	1997-05-21	Fungizide zusammensetzung mit erhörter bioverfügbarkeit

Country Status (27)

Country	Link
EP (1)	EP0914127B1 (de)
JP (1)	JP3366648B2 (de)
KR (1)	KR100307427B1 (de)
CN (1)	CN1121860C (de)
AR (1)	AR007250A1 (de)
AT (1)	ATE213632T1 (de)
AU (1)	AU719109B2 (de)
BR (1)	BR9711167A (de)
CA (1)	CA2255663C (de)
CO (1)	CO4840511A1 (de)
CZ (1)	CZ293586B6 (de)
DE (1)	DE69710729T2 (de)
ES (1)	ES2169440T3 (de)
HU (1)	HU221371B1 (de)
ID (1)	ID16956A (de)
IL (1)	IL126979A (de)
MY (1)	MY118988A (de)
NO (1)	NO316997B1 (de)
NZ (1)	NZ332699A (de)
PE (1)	PE68898A1 (de)
PL (1)	PL188401B1 (de)
RU (1)	RU2207119C2 (de)
SK (1)	SK281818B6 (de)
TR (1)	TR199802424T2 (de)
TW (1)	TW504390B (de)
WO (1)	WO1998007429A2 (de)
ZA (1)	ZA974428B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2157731B1 (es) *	1998-07-21	2002-05-01	Liconsa Liberacion Controlada	Preparacion farmaceutica oral de un compuesto de actividad antifungica y procedimiento para su preparacion.
WO2001034119A2 (en)	1999-11-12	2001-05-17	Abbott Laboratories	Inhibitors of crystallization in a solid dispersion
DE10026698A1 (de)	2000-05-30	2001-12-06	Basf Ag	Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
MEP27808A (en) *	2001-01-26	2010-10-10	Schering Corp	Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
WO2004066981A1 (en) *	2003-01-29	2004-08-12	Sun Pharmaceutical Industries Limited	Oral controlled release pharmaceutical composition containing metaxalone as active agent
US8025899B2 (en)	2003-08-28	2011-09-27	Abbott Laboratories	Solid pharmaceutical dosage form
PH12013500882A1 (en) *	2010-11-01	2020-10-19	Melinta Subsidiary Corp	Pharmaceutical compositions
RU2450807C1 (ru) *	2011-05-11	2012-05-20	Общество с ограниченной ответственностью фирма "Вита"	Стабилизированный фармацевтический состав с противогрибковым действием
CN103845292A (zh) *	2012-11-29	2014-06-11	正大天晴药业集团股份有限公司	泊沙康唑微丸及其制备方法
US9763934B2 (en) *	2014-03-05	2017-09-19	Professional Compounding Centers Of America	Synergistic effect of poloxamer-based composition and itraconazole on fungus and yeast
TR201620462A2 (tr)	2016-12-31	2018-07-23	Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi	POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4791111A (en) *	1985-12-23	1988-12-13	Janssen Pharmaceutica, N.V.	[[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
RU2039050C1 (ru) *	1989-09-26	1995-07-09	Такеда Кемикал Индастриз ЛТД	Производные 1,2,4-триазола, оптически инертные или имеющие r- или s-конфигурацию c-2 и c-3 асимметричных центров, или их соли, обладающие фунгицидной активностью, и способ их получения
GB9002375D0 (en) *	1990-02-02	1990-04-04	Pfizer Ltd	Triazole antifungal agents
US5039676A (en) *	1990-05-11	1991-08-13	Schering Corporation	Tri- and tetra-substituted-oxetanes and tetrahydrofurans and intermediates thereof
ZA9410142B (en)	1993-12-21	1996-05-02	Schering Corp	Tetrahydrofuran antifungals

1997
- 1997-05-21 JP JP50544798A patent/JP3366648B2/ja not_active Expired - Fee Related
- 1997-05-21 CA CA002255663A patent/CA2255663C/en not_active Expired - Fee Related
- 1997-05-21 HU HU9904265A patent/HU221371B1/hu not_active IP Right Cessation
- 1997-05-21 AT AT97949341T patent/ATE213632T1/de not_active IP Right Cessation
- 1997-05-21 ID IDP971708A patent/ID16956A/id unknown
- 1997-05-21 IL IL12697997A patent/IL126979A/xx not_active IP Right Cessation
- 1997-05-21 WO PCT/US1997/019388 patent/WO1998007429A2/en not_active Ceased
- 1997-05-21 NZ NZ332699A patent/NZ332699A/xx not_active IP Right Cessation
- 1997-05-21 DE DE69710729T patent/DE69710729T2/de not_active Expired - Lifetime
- 1997-05-21 TR TR1998/02424T patent/TR199802424T2/xx unknown
- 1997-05-21 CO CO97027673A patent/CO4840511A1/es unknown
- 1997-05-21 BR BR9711167A patent/BR9711167A/pt not_active IP Right Cessation
- 1997-05-21 PE PE1997000400A patent/PE68898A1/es not_active Application Discontinuation
- 1997-05-21 ES ES97949341T patent/ES2169440T3/es not_active Expired - Lifetime
- 1997-05-21 PL PL97330480A patent/PL188401B1/pl not_active IP Right Cessation
- 1997-05-21 EP EP97949341A patent/EP0914127B1/de not_active Expired - Lifetime
- 1997-05-21 RU RU98123611/14A patent/RU2207119C2/ru not_active IP Right Cessation
- 1997-05-21 AU AU59399/98A patent/AU719109B2/en not_active Ceased
- 1997-05-21 CN CN97196513A patent/CN1121860C/zh not_active Expired - Fee Related
- 1997-05-21 KR KR1019980709501A patent/KR100307427B1/ko not_active Expired - Fee Related
- 1997-05-21 TW TW086106780A patent/TW504390B/zh not_active IP Right Cessation
- 1997-05-21 SK SK1608-98A patent/SK281818B6/sk not_active IP Right Cessation
- 1997-05-21 CZ CZ19983790A patent/CZ293586B6/cs not_active IP Right Cessation
- 1997-05-21 ZA ZA9704428A patent/ZA974428B/xx unknown
- 1997-05-22 MY MYPI97002234A patent/MY118988A/en unknown
- 1997-05-22 AR ARP970102173A patent/AR007250A1/es active IP Right Grant
1998
- 1998-11-23 NO NO19985447A patent/NO316997B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE213632T1 (de)	2002-03-15
CA2255663C (en)	2002-08-20
WO1998007429A2 (en)	1998-02-26
CZ293586B6 (cs)	2004-06-16
CO4840511A1 (es)	1999-09-27
KR100307427B1 (ko)	2001-12-28
KR20000065222A (ko)	2000-11-06
BR9711167A (pt)	1999-08-17
PL330480A1 (en)	1999-05-24
EP0914127B1 (de)	2002-02-27
JP3366648B2 (ja)	2003-01-14
NO985447D0 (no)	1998-11-23
HUP9904265A3 (en)	2000-05-29
HU221371B1 (en)	2002-09-28
NZ332699A (en)	2000-01-28
JP2000509720A (ja)	2000-08-02
HUP9904265A2 (hu)	2000-04-28
AR007250A1 (es)	1999-10-27
DE69710729T2 (de)	2002-08-14
ID16956A (id)	1997-11-27
CA2255663A1 (en)	1998-02-26
TW504390B (en)	2002-10-01
WO1998007429A3 (en)	1998-04-23
AU5939998A (en)	1998-03-06
EP0914127A2 (de)	1999-05-12
IL126979A (en)	2000-10-31
PE68898A1 (es)	1998-11-10
CZ379098A3 (cs)	1999-03-17
CN1121860C (zh)	2003-09-24
NO316997B1 (no)	2004-07-19
HK1017855A1 (en)	1999-12-03
MY118988A (en)	2005-02-28
TR199802424T2 (xx)	1999-03-22
SK160898A3 (en)	1999-05-07
IL126979A0 (en)	1999-09-22
ES2169440T3 (es)	2002-07-01
ZA974428B (en)	1997-11-24
CN1228699A (zh)	1999-09-15
PL188401B1 (pl)	2005-01-31
SK281818B6 (sk)	2001-08-06
RU2207119C2 (ru)	2003-06-27
NO985447L (no)	1998-11-23
AU719109B2 (en)	2000-05-04

Publication	Publication Date	Title
NO982599L (no)	1998-11-19	Antifungale sammensetninger med forbedret biotilgjenelighet
DE59707564D1 (de)	2002-07-25	Fungizide mischung
BR9607925A (pt)	1998-06-09	Composição fungicida
ATE215310T1 (de)	2002-04-15	Fungizide mischungen
ATE237939T1 (de)	2003-05-15	Fungizide mischungen
DE69717927D1 (de)	2003-01-30	Insektizide Zusammensetzung
ATE228763T1 (de)	2002-12-15	Fungizide mischungen
DE69710729D1 (de)	2002-04-04	Fungizide zusammensetzung mit erhörter bioverfügbarkeit
ATE268553T1 (de)	2004-06-15	Fungizide zusammensetzung
DE69700755D1 (de)	1999-12-16	Mikrobizide Zusammensetzung
ATE214874T1 (de)	2002-04-15	Fungizide mischungen
DK0967869T3 (da)	2003-07-14	Fungicidblandinger
ATE204708T1 (de)	2001-09-15	Fungizide mischungen
DE59706103D1 (de)	2002-03-07	Fungizide mischungen
ATE229270T1 (de)	2002-12-15	Fungizide mischungen
DE59707655D1 (de)	2002-08-08	Fungizide mischungen
DE59704457D1 (de)	2001-10-04	Fungizide mischungen
DE69702094D1 (de)	2000-06-29	N-Acetonylbenzamidverbindungen mit fungizider Aktivität
DE59707602D1 (de)	2002-08-01	Fungizide mischungen
ATE245352T1 (de)	2003-08-15	Fungizide mischungen
DE59706870D1 (de)	2002-05-08	Fungizide mischung
ATE225127T1 (de)	2002-10-15	Fungizide mischungen
ATE214876T1 (de)	2002-04-15	Fungizide mischungen
DE69700503D1 (de)	1999-10-21	Fungizide Zusammensetzung
DE59706871D1 (de)	2002-05-08	Fungizide mischungen