[go: up one dir, main page]

DE60137206D1 - Herstellung von fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethylether - Google Patents

Herstellung von fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethylether

Info

Publication number
DE60137206D1
DE60137206D1 DE60137206T DE60137206T DE60137206D1 DE 60137206 D1 DE60137206 D1 DE 60137206D1 DE 60137206 T DE60137206 T DE 60137206T DE 60137206 T DE60137206 T DE 60137206T DE 60137206 D1 DE60137206 D1 DE 60137206D1
Authority
DE
Germany
Prior art keywords
fluoromethyl
trifluoro
trifluoromethyl
preparation
ethyl ether
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60137206T
Other languages
English (en)
Inventor
Ashot Khrimian
Barry Malcolm Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Halocarbon Products Corp
Original Assignee
Halocarbon Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Halocarbon Products Corp filed Critical Halocarbon Products Corp
Application granted granted Critical
Publication of DE60137206D1 publication Critical patent/DE60137206D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B7/00—Halogens; Halogen acids
    • C01B7/19—Fluorine; Hydrogen fluoride
    • C01B7/191—Hydrogen fluoride
    • C01B7/195—Separation; Purification
    • C01B7/196—Separation; Purification by distillation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/34—Separation; Purification; Stabilisation; Use of additives
    • C07C41/40—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation
    • C07C41/42—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation by distillation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/12—Saturated ethers containing halogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60137206T 2000-03-16 2001-03-15 Herstellung von fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethylether Expired - Lifetime DE60137206D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/527,045 US6469219B1 (en) 2000-03-16 2000-03-16 Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
PCT/US2001/009547 WO2001068577A1 (en) 2000-03-16 2001-03-15 Production of fluormethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether

Publications (1)

Publication Number Publication Date
DE60137206D1 true DE60137206D1 (de) 2009-02-12

Family

ID=24099874

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60137206T Expired - Lifetime DE60137206D1 (de) 2000-03-16 2001-03-15 Herstellung von fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethylether
DE08173108T Pending DE08173108T1 (de) 2000-03-16 2001-03-15 Herstellung von Fluormethyl-2,2,2-trifluor-1-(trifluormethyl)ethylether

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE08173108T Pending DE08173108T1 (de) 2000-03-16 2001-03-15 Herstellung von Fluormethyl-2,2,2-trifluor-1-(trifluormethyl)ethylether

Country Status (15)

Country Link
US (1) US6469219B1 (de)
EP (3) EP2036877B1 (de)
JP (4) JP4112862B2 (de)
KR (3) KR100685070B1 (de)
CN (2) CN100515926C (de)
AT (1) ATE419228T1 (de)
AU (1) AU2001249438A1 (de)
BR (1) BR0109376A (de)
CA (3) CA2691933A1 (de)
CZ (1) CZ304716B6 (de)
DE (2) DE60137206D1 (de)
ES (2) ES2320720T1 (de)
HU (1) HUP0300589A3 (de)
PL (1) PL202495B1 (de)
WO (1) WO2001068577A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6469219B1 (en) * 2000-03-16 2002-10-22 Halocarbon Products Corporation Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
BRPI0406766B8 (pt) * 2003-01-14 2021-05-25 Baxter Int processo para a recuperação de 1,1,1,3,3,3-hexafluoroisopropanol a partir de corrente de rejeitos de síntese de sevoflurano
JP2007518078A (ja) * 2004-01-05 2007-07-05 ヘイロウカーボン プロダクツ コーポレイション プロセス中及び完成セボフルランの両方の分析のクロマトグラフ法
CA2597788C (en) * 2005-02-15 2013-07-09 Halocarbon Products Corporation Separation/purification of desflurane from hydrogen fluoride
CN101263102B (zh) * 2005-08-04 2011-08-17 碳卤化合物产品公司 氟甲基1,1,1,3,3,3-六氟异丙基醚（七氟烷）的纯化
JP5315609B2 (ja) * 2006-06-05 2013-10-16 ダイキン工業株式会社 新規カルボン酸化合物、その用途及びその製造方法
JP5114880B2 (ja) 2006-07-06 2013-01-09 ダイキン工業株式会社 新規α−フルオロメトキシカルボン酸エステル、該α−フルオロメトキシカルボン酸エステルの製造方法及びセボフルランの製造方法
JP5163064B2 (ja) 2007-11-13 2013-03-13 ダイキン工業株式会社 新規カルボン酸エステル、その用途及びその製造方法
US7732647B2 (en) * 2007-12-27 2010-06-08 Halocarbon Products Corporation Process for the purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane)
US20090275785A1 (en) * 2008-05-01 2009-11-05 Barry Jones Distillation Method For The Purification Of Sevoflurane And The Maintenance Of Certain Equipment That May Be Used In The Distillation Process
CN101659603B (zh) 2008-08-27 2014-05-07 中化蓝天集团有限公司 一种制备氟甲基-1,1,1,3,3,3-六氟异丙基醚的方法
JP5434236B2 (ja) 2009-04-28 2014-03-05 セントラル硝子株式会社 フルオロメチルヘキサフルオロイソプロピルエーテルの製造方法
US9102604B1 (en) 2010-02-15 2015-08-11 Baxter International Inc. Methods for cleaning distilling columns
DE102011077681A1 (de) 2011-06-17 2012-12-20 Evonik Degussa Gmbh Verfahren zur Herstellung von 3-Cyano-3,5,5-trimethylcyclohexanon
US8729313B2 (en) 2011-08-15 2014-05-20 Baxter International Inc. Process for the manufacturing of sevoflurane
JP7670992B2 (ja) * 2020-03-19 2025-05-01 セントラル硝子株式会社 （ハイドロ）ハロカーボンの製造方法
CN113943214B (zh) * 2021-11-11 2023-12-19 福建海西联合药业有限公司 一种运用于七氟烷生产的工艺
CN120025236B (zh) * 2025-04-21 2025-06-27 江苏恒瑞医药股份有限公司 一种制备七氟烷及其中间体的方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2425752A (en) * 1944-09-15 1947-08-19 Phillips Petroleum Co Separation of hydrogen fluoride from water and organic contaminants by distillation and decantation
US2992276A (en) * 1959-05-20 1961-07-11 Du Pont Process for preparing polyfluoro alkyl compounds
US3911024A (en) 1966-12-08 1975-10-07 Louise S Croix Fluorinated isopropyl derivatives
US3689571A (en) * 1970-07-31 1972-09-05 Baxter Laboratories Inc Fluorinated ether
US3683092A (en) * 1970-07-31 1972-08-08 Baxter Laboratories Inc Method of anesthesia
US3773907A (en) * 1971-03-09 1973-11-20 Buss Ag Process for the production of pure concentrated hf from impure fluosilicic acid
US3897502A (en) 1971-10-22 1975-07-29 Airco Inc Process for making fluorinated ethers
USRE29084E (en) * 1974-04-17 1976-12-21 Universal Oil Products Company Separate recycle of regenerated acid and of isoparaffin from HF catalyst regeneration zone
US4250334A (en) * 1979-12-26 1981-02-10 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4469898A (en) * 1979-12-26 1984-09-04 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4314087A (en) * 1979-12-26 1982-02-02 Baxter Travenol Laboratories, Inc. Methods of synthesizing hexafluoroisopropanol from impure mixtures and synthesis of a fluoromethyl ether therefrom
US4874901A (en) 1988-05-06 1989-10-17 Boc, Inc. Process for the production of polyfluorinated ethers
US4874902A (en) 1988-05-20 1989-10-17 Boc, Inc. Method for the preparation of fluoromethyl 1,1,1,3,3,3-hexafluoro-2-propyl ether
GB9124087D0 (en) * 1991-11-13 1992-01-02 Ici Plc Chemical process
EP0518506B1 (de) * 1991-06-14 1997-08-20 Imperial Chemical Industries Plc Herstellung von Bis(fluormethyl)äther und von Difluormethan
JPH0532568A (ja) * 1991-07-31 1993-02-09 Daikin Ind Ltd フツ化水素とジクロロフルオロメタンの混合物からフツ化水素を除去する方法
CA2068068A1 (en) * 1991-08-30 1993-03-01 James H. Mestepey Recovery of anhydrous hydrogen fluoride from depleted uranium
GB9126355D0 (en) * 1991-12-11 1992-02-12 Ici Plc Production of hydrofluorocarbons
GB9208769D0 (en) * 1992-04-23 1992-06-10 Ici Plc Production of bis (fluoromethyl) ether and difluoromethane
JP2865554B2 (ja) * 1994-04-08 1999-03-08 セントラル硝子株式会社 フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルのガスクロマトグラフ分析
GB9600072D0 (en) 1996-01-04 1996-03-06 Ici Plc Process for the production of fluoromethylhexafluoroisopropylether
JP3240043B2 (ja) * 1996-01-23 2001-12-17 セントラル硝子株式会社 フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルの精製方法
US5811596A (en) 1996-02-21 1998-09-22 Central Glass Co., Ltd. Method of producing fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether
US6352677B1 (en) * 1996-06-04 2002-03-05 Alliedsignal, Inc. Process to produce commercial grade anhydrous hydrogen fluoride (AHF) and uranium oxide from the delfuorination of uranium hexafluoride (UF6)
GB9616879D0 (en) * 1996-08-10 1996-09-25 Ici Plc Removal of water from process streams
US5705710A (en) 1997-01-15 1998-01-06 University Of Iowa Research Foundation Process for the synthesis of hexafluoroisopropyl ethers
US5969193A (en) * 1997-08-18 1999-10-19 Medeva Pharmaceuticals Pa, Inc. Method for the preparation of sevoflurane
US5886239A (en) 1997-11-21 1999-03-23 Baxter International Inc. Method of preparing monofluoromethyl ethers
US6469219B1 (en) * 2000-03-16 2002-10-22 Halocarbon Products Corporation Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether

Also Published As

Publication number Publication date
EP2036877A3 (de) 2009-07-15
KR100698653B1 (ko) 2007-03-23
ES2320720T1 (es) 2009-05-28
CA2689573C (en) 2012-05-22
KR20050105289A (ko) 2005-11-03
DE08173108T1 (de) 2009-08-13
KR100685072B1 (ko) 2007-02-22
EP1268381A1 (de) 2003-01-02
HUP0300589A3 (en) 2003-10-28
JP2008143915A (ja) 2008-06-26
US6469219B1 (en) 2002-10-22
CA2691933A1 (en) 2001-09-20
CA2403105C (en) 2010-02-16
CN100509735C (zh) 2009-07-08
EP1268381A4 (de) 2004-10-20
JP4112862B2 (ja) 2008-07-02
CN1636864A (zh) 2005-07-13
CA2689573A1 (en) 2001-09-20
PL365368A1 (en) 2004-12-27
CA2403105A1 (en) 2001-09-20
CN100515926C (zh) 2009-07-22
ES2319162T3 (es) 2009-05-05
EP1268381B1 (de) 2008-12-31
JP5086118B2 (ja) 2012-11-28
JP2014005287A (ja) 2014-01-16
KR20050107528A (ko) 2005-11-11
WO2001068577A1 (en) 2001-09-20
CZ20023069A3 (cs) 2003-05-14
JP2011207902A (ja) 2011-10-20
BR0109376A (pt) 2004-01-13
KR20020082886A (ko) 2002-10-31
EP2272816A1 (de) 2011-01-12
CN1430592A (zh) 2003-07-16
EP2036877A2 (de) 2009-03-18
PL202495B1 (pl) 2009-06-30
JP2003530323A (ja) 2003-10-14
EP2036877B1 (de) 2015-08-12
JP5711050B2 (ja) 2015-04-30
CZ304716B6 (cs) 2014-09-10
AU2001249438A1 (en) 2001-09-24
ATE419228T1 (de) 2009-01-15
HUP0300589A2 (hu) 2003-07-28
KR100685070B1 (ko) 2007-02-22

Similar Documents

Publication Publication Date Title
DE60137206D1 (de) Herstellung von fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethylether
EP1401433A4 (de) Gehemmte konformationsanaloga als mittel gegen diabetes und adipositas und verfahren
AR066694A2 (es) Metodo para la preparacion de citalopram
BG105692A (en) Method for the preparation of 5-cyanophthalide
ATE219040T1 (de) Verfahren zur herstellung von sevoflurane
DE60142051D1 (de) Herstellung von perfluorolefinen
ATE157075T1 (de) Herstellung von bis(fluormethyl)äther und von difluormethan
DE60123034D1 (de) Herstellung von sekundären aminoisobutylalkoxysilanen
BR9914444A (pt) Dióxido de silìcio, processo para a preparação do mesmo, uso do mesmo, peça moldada e catalisador
PT1204659E (pt) Benzofuranos serotoninergicos
DE60136463D1 (de) Verfahren zur herstellung von fluorierten acyl fluoriden und fluorierten vinylethern
DE50111886D1 (de) Verfahren zur Herstellung von Fluor enthaltenden Benzaldehyden
GT199900047A (es) Procedimiento para alquilar sulfonamidas impedidas estèricamente.
DE69715733D1 (de) Verfahren zur Herstellung von 5-Brom-2-Fluorbenzolboronsäure
RU97107033A (ru) Абсорбент для очистки газов от h2s и co2
BR0100131A (pt) Processo para misturação de um gás e um lìquido dentro de um recipiente fechado possuindo um espaço de gás superior, e, aparelhagem para misturação de um gás e um lìquido durante a operação de misturação
DE60120985D1 (de) Verwendung von fibrate zur herstellung eines arzneimittel zur behandlung von kongestiven herzversagens
DE69008036D1 (de) Verfahren zur Herstellung von aromatischen Ethern.
DE60132856D1 (de) Verfahren zur Herstellung von Wismut-basierten Hochtemperatur-Supraleitern
PL361172A1 (en) 1,3-dioxolanes with antitussive activity
PT1307440E (pt) 1,3-dioxolanos dissubstituidos em 2,2 como agentes antitussicos
DE3750062D1 (de) Benzothiazolone, ihre Herstellung und Anwendung als Herbizide.
DK0948338T3 (da) Anvendelse af et på æg baseret præparat som antidepressivt middel
Maguidova et al. Modelling guide to English idiomaticity
Nefedova Quality of professional operator training on example of Sevastopol Institute of nuclear power and industry; Kachestvo podgotovki spetsialistov dlya raboty na AES na primere Sevastopol'skogo Instituta yadernoj ehnergii i promyshlennosti

Legal Events

Date Code Title Description
8364 No opposition during term of opposition