AU2001249438A1 - Production of fluormethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether - Google Patents
Production of fluormethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl etherInfo
- Publication number
- AU2001249438A1 AU2001249438A1 AU2001249438A AU4943801A AU2001249438A1 AU 2001249438 A1 AU2001249438 A1 AU 2001249438A1 AU 2001249438 A AU2001249438 A AU 2001249438A AU 4943801 A AU4943801 A AU 4943801A AU 2001249438 A1 AU2001249438 A1 AU 2001249438A1
- Authority
- AU
- Australia
- Prior art keywords
- fluormethyl
- trifluoro
- trifluoromethyl
- production
- ethyl ether
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- CXJWJJZGJZNBRK-UHFFFAOYSA-N 1,1,1,3,3,3-hexafluoro-2-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)propane Chemical compound FC(F)(F)C(C(F)(F)F)OC(C(F)(F)F)C(F)(F)F CXJWJJZGJZNBRK-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 4
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 abstract 3
- 229910000040 hydrogen fluoride Inorganic materials 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 238000009835 boiling Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B7/00—Halogens; Halogen acids
- C01B7/19—Fluorine; Hydrogen fluoride
- C01B7/191—Hydrogen fluoride
- C01B7/195—Separation; Purification
- C01B7/196—Separation; Purification by distillation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/34—Separation; Purification; Stabilisation; Use of additives
- C07C41/40—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation
- C07C41/42—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation by distillation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/04—Saturated ethers
- C07C43/12—Saturated ethers containing halogen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A process for removing water from a mixture comprising hydrogen fluoride and water, said process comprising:
a) providing a mixture comprising hydrogen fluoride and water; and
b) removing water from the mixture as a constant boiling mixture with hydrogen fluoride.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/527,045 US6469219B1 (en) | 2000-03-16 | 2000-03-16 | Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether |
| US09527045 | 2000-03-16 | ||
| PCT/US2001/009547 WO2001068577A1 (en) | 2000-03-16 | 2001-03-15 | Production of fluormethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001249438A1 true AU2001249438A1 (en) | 2001-09-24 |
Family
ID=24099874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001249438A Abandoned AU2001249438A1 (en) | 2000-03-16 | 2001-03-15 | Production of fluormethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6469219B1 (en) |
| EP (3) | EP2272816A1 (en) |
| JP (4) | JP4112862B2 (en) |
| KR (3) | KR100685070B1 (en) |
| CN (2) | CN100515926C (en) |
| AT (1) | ATE419228T1 (en) |
| AU (1) | AU2001249438A1 (en) |
| BR (1) | BR0109376A (en) |
| CA (3) | CA2691933A1 (en) |
| CZ (1) | CZ304716B6 (en) |
| DE (2) | DE60137206D1 (en) |
| ES (2) | ES2319162T3 (en) |
| HU (1) | HUP0300589A3 (en) |
| PL (1) | PL202495B1 (en) |
| WO (1) | WO2001068577A1 (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6469219B1 (en) * | 2000-03-16 | 2002-10-22 | Halocarbon Products Corporation | Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether |
| US6987204B2 (en) * | 2003-01-14 | 2006-01-17 | Baxter International Inc. | Process for recovery of 1,1,1,3,3,3-hexafluoroisopropanol from the waste stream of sevoflurane synthesis |
| CZ2006444A3 (en) * | 2004-01-05 | 2007-02-07 | Halocarbon Products Corporation | Chromatographic method for the analysis of both in process and finished sevoflurane |
| CN101119953B (en) * | 2005-02-15 | 2011-02-16 | 碳卤化合物产品公司 | Separation/purification of desflurane from hydrogen fluoride |
| US7750192B2 (en) * | 2005-08-04 | 2010-07-06 | Halocarbon Products Corporation | Purification of Fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane) |
| JP5315609B2 (en) * | 2006-06-05 | 2013-10-16 | ダイキン工業株式会社 | Novel carboxylic acid compound, its use and production method |
| JP5114880B2 (en) | 2006-07-06 | 2013-01-09 | ダイキン工業株式会社 | Novel α-fluoromethoxycarboxylic acid ester, method for producing the α-fluoromethoxycarboxylic acid ester, and method for producing sevoflurane |
| JP5163064B2 (en) * | 2007-11-13 | 2013-03-13 | ダイキン工業株式会社 | Novel carboxylic acid ester, its use and production method |
| US7732647B2 (en) * | 2007-12-27 | 2010-06-08 | Halocarbon Products Corporation | Process for the purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane) |
| US20090275785A1 (en) * | 2008-05-01 | 2009-11-05 | Barry Jones | Distillation Method For The Purification Of Sevoflurane And The Maintenance Of Certain Equipment That May Be Used In The Distillation Process |
| CN101659603B (en) | 2008-08-27 | 2014-05-07 | 中化蓝天集团有限公司 | Method for preparing fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether |
| JP5434236B2 (en) | 2009-04-28 | 2014-03-05 | セントラル硝子株式会社 | Method for producing fluoromethylhexafluoroisopropyl ether |
| US9102604B1 (en) | 2010-02-15 | 2015-08-11 | Baxter International Inc. | Methods for cleaning distilling columns |
| DE102011077681A1 (en) | 2011-06-17 | 2012-12-20 | Evonik Degussa Gmbh | Process for the preparation of 3-cyano-3,5,5-trimethylcyclohexanone |
| US8729313B2 (en) | 2011-08-15 | 2014-05-20 | Baxter International Inc. | Process for the manufacturing of sevoflurane |
| JP7670992B2 (en) * | 2020-03-19 | 2025-05-01 | セントラル硝子株式会社 | Method for producing (hydro)halocarbons |
| CN113943214B (en) * | 2021-11-11 | 2023-12-19 | 福建海西联合药业有限公司 | Process for producing sevoflurane |
| CN120025236B (en) * | 2025-04-21 | 2025-06-27 | 江苏恒瑞医药股份有限公司 | Method for preparing sevoflurane and intermediate thereof |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2425752A (en) * | 1944-09-15 | 1947-08-19 | Phillips Petroleum Co | Separation of hydrogen fluoride from water and organic contaminants by distillation and decantation |
| US2992276A (en) * | 1959-05-20 | 1961-07-11 | Du Pont | Process for preparing polyfluoro alkyl compounds |
| US3911024A (en) | 1966-12-08 | 1975-10-07 | Louise S Croix | Fluorinated isopropyl derivatives |
| US3683092A (en) * | 1970-07-31 | 1972-08-08 | Baxter Laboratories Inc | Method of anesthesia |
| US3689571A (en) * | 1970-07-31 | 1972-09-05 | Baxter Laboratories Inc | Fluorinated ether |
| US3773907A (en) * | 1971-03-09 | 1973-11-20 | Buss Ag | Process for the production of pure concentrated hf from impure fluosilicic acid |
| US3897502A (en) | 1971-10-22 | 1975-07-29 | Airco Inc | Process for making fluorinated ethers |
| USRE29084E (en) * | 1974-04-17 | 1976-12-21 | Universal Oil Products Company | Separate recycle of regenerated acid and of isoparaffin from HF catalyst regeneration zone |
| US4314087A (en) * | 1979-12-26 | 1982-02-02 | Baxter Travenol Laboratories, Inc. | Methods of synthesizing hexafluoroisopropanol from impure mixtures and synthesis of a fluoromethyl ether therefrom |
| US4469898A (en) * | 1979-12-26 | 1984-09-04 | Baxter Travenol Laboratories, Inc. | Method of synthesizing fluoromethylhexafluoroisopropyl ether |
| US4250334A (en) * | 1979-12-26 | 1981-02-10 | Baxter Travenol Laboratories, Inc. | Method of synthesizing fluoromethylhexafluoroisopropyl ether |
| US4874901A (en) | 1988-05-06 | 1989-10-17 | Boc, Inc. | Process for the production of polyfluorinated ethers |
| US4874902A (en) | 1988-05-20 | 1989-10-17 | Boc, Inc. | Method for the preparation of fluoromethyl 1,1,1,3,3,3-hexafluoro-2-propyl ether |
| EP0518506B1 (en) * | 1991-06-14 | 1997-08-20 | Imperial Chemical Industries Plc | Production of bis(fluoromethyl)ether and difluoromethane |
| GB9124087D0 (en) * | 1991-11-13 | 1992-01-02 | Ici Plc | Chemical process |
| JPH0532568A (en) * | 1991-07-31 | 1993-02-09 | Daikin Ind Ltd | Method for removing hydrogen fluoride from a mixture of hydrogen fluoride and dichlorofluoromethane |
| CA2068068A1 (en) * | 1991-08-30 | 1993-03-01 | James H. Mestepey | Recovery of anhydrous hydrogen fluoride from depleted uranium |
| GB9126355D0 (en) * | 1991-12-11 | 1992-02-12 | Ici Plc | Production of hydrofluorocarbons |
| GB9208769D0 (en) * | 1992-04-23 | 1992-06-10 | Ici Plc | Production of bis (fluoromethyl) ether and difluoromethane |
| JP2865554B2 (en) * | 1994-04-08 | 1999-03-08 | セントラル硝子株式会社 | Gas chromatographic analysis of fluoromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether |
| GB9600072D0 (en) | 1996-01-04 | 1996-03-06 | Ici Plc | Process for the production of fluoromethylhexafluoroisopropylether |
| JP3240043B2 (en) * | 1996-01-23 | 2001-12-17 | セントラル硝子株式会社 | Purification method of fluoromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether |
| US5811596A (en) | 1996-02-21 | 1998-09-22 | Central Glass Co., Ltd. | Method of producing fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether |
| US6352677B1 (en) * | 1996-06-04 | 2002-03-05 | Alliedsignal, Inc. | Process to produce commercial grade anhydrous hydrogen fluoride (AHF) and uranium oxide from the delfuorination of uranium hexafluoride (UF6) |
| GB9616879D0 (en) * | 1996-08-10 | 1996-09-25 | Ici Plc | Removal of water from process streams |
| US5705710A (en) | 1997-01-15 | 1998-01-06 | University Of Iowa Research Foundation | Process for the synthesis of hexafluoroisopropyl ethers |
| US5969193A (en) | 1997-08-18 | 1999-10-19 | Medeva Pharmaceuticals Pa, Inc. | Method for the preparation of sevoflurane |
| US5886239A (en) | 1997-11-21 | 1999-03-23 | Baxter International Inc. | Method of preparing monofluoromethyl ethers |
| US6469219B1 (en) * | 2000-03-16 | 2002-10-22 | Halocarbon Products Corporation | Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether |
-
2000
- 2000-03-16 US US09/527,045 patent/US6469219B1/en not_active Expired - Lifetime
-
2001
- 2001-03-15 DE DE60137206T patent/DE60137206D1/en not_active Expired - Lifetime
- 2001-03-15 AU AU2001249438A patent/AU2001249438A1/en not_active Abandoned
- 2001-03-15 JP JP2001567676A patent/JP4112862B2/en not_active Expired - Fee Related
- 2001-03-15 KR KR1020057019924A patent/KR100685070B1/en not_active Expired - Fee Related
- 2001-03-15 WO PCT/US2001/009547 patent/WO2001068577A1/en not_active Ceased
- 2001-03-15 CA CA002691933A patent/CA2691933A1/en not_active Abandoned
- 2001-03-15 HU HU0300589A patent/HUP0300589A3/en unknown
- 2001-03-15 CZ CZ2002-3069A patent/CZ304716B6/en not_active IP Right Cessation
- 2001-03-15 AT AT01922664T patent/ATE419228T1/en not_active IP Right Cessation
- 2001-03-15 EP EP10183963A patent/EP2272816A1/en not_active Withdrawn
- 2001-03-15 BR BR0109376-2A patent/BR0109376A/en active Search and Examination
- 2001-03-15 DE DE08173108T patent/DE08173108T1/en active Pending
- 2001-03-15 PL PL365368A patent/PL202495B1/en unknown
- 2001-03-15 ES ES01922664T patent/ES2319162T3/en not_active Expired - Lifetime
- 2001-03-15 CA CA2403105A patent/CA2403105C/en not_active Expired - Fee Related
- 2001-03-15 CN CNB200410011582XA patent/CN100515926C/en not_active Expired - Fee Related
- 2001-03-15 ES ES08173108T patent/ES2320720T1/en active Pending
- 2001-03-15 KR KR1020057019923A patent/KR100685072B1/en not_active Expired - Fee Related
- 2001-03-15 EP EP08173108.5A patent/EP2036877B1/en not_active Expired - Lifetime
- 2001-03-15 EP EP01922664A patent/EP1268381B1/en not_active Expired - Lifetime
- 2001-03-15 KR KR1020027012180A patent/KR100698653B1/en not_active Expired - Fee Related
- 2001-03-15 CN CNB018075819A patent/CN100509735C/en not_active Expired - Fee Related
- 2001-03-15 CA CA2689573A patent/CA2689573C/en not_active Expired - Fee Related
-
2008
- 2008-02-06 JP JP2008026830A patent/JP5086118B2/en not_active Expired - Fee Related
-
2011
- 2011-05-31 JP JP2011122368A patent/JP5711050B2/en not_active Expired - Lifetime
-
2013
- 2013-09-05 JP JP2013184221A patent/JP2014005287A/en active Pending
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