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DE60113663D1 - Neue fettsäureanaloga - Google Patents

Neue fettsäureanaloga

Info

Publication number
DE60113663D1
DE60113663D1 DE60113663T DE60113663T DE60113663D1 DE 60113663 D1 DE60113663 D1 DE 60113663D1 DE 60113663 T DE60113663 T DE 60113663T DE 60113663 T DE60113663 T DE 60113663T DE 60113663 D1 DE60113663 D1 DE 60113663D1
Authority
DE
Germany
Prior art keywords
carbon
fatty acid
alkyl
coor2
proviso
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60113663T
Other languages
English (en)
Other versions
DE60113663T2 (de
Inventor
Rolf Berge
K Sydnes
Jon Songstad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thia Medica AS
Original Assignee
Thia Medica AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thia Medica AS filed Critical Thia Medica AS
Application granted granted Critical
Publication of DE60113663D1 publication Critical patent/DE60113663D1/de
Publication of DE60113663T2 publication Critical patent/DE60113663T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/60Unsaturated compounds containing ether groups, groups, groups, or groups the non-carboxylic part of the ether being unsaturated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C391/00Compounds containing selenium
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03Monocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/18Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon triple bonds as unsaturation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Edible Oils And Fats (AREA)
  • Pyrane Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60113663T 2000-03-03 2001-03-02 Neue fettsäureanaloga Expired - Lifetime DE60113663T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20001123 2000-03-03
NO20001123A NO328803B1 (no) 2000-03-03 2000-03-03 Nye fettsyreanaloger
PCT/NO2001/000082 WO2001068582A1 (en) 2000-03-03 2001-03-02 Novel fatty acid analogous

Publications (2)

Publication Number Publication Date
DE60113663D1 true DE60113663D1 (de) 2006-02-09
DE60113663T2 DE60113663T2 (de) 2006-07-27

Family

ID=19910832

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60113663T Expired - Lifetime DE60113663T2 (de) 2000-03-03 2001-03-02 Neue fettsäureanaloga

Country Status (17)

Country Link
US (1) US7902399B2 (de)
EP (1) EP1265838B9 (de)
JP (1) JP5122050B2 (de)
KR (3) KR100940373B1 (de)
CN (1) CN1283611C (de)
AT (1) ATE305447T1 (de)
AU (2) AU2001237835B2 (de)
BR (1) BR0108950A (de)
CA (1) CA2401757C (de)
DE (1) DE60113663T2 (de)
DK (1) DK1265838T3 (de)
ES (1) ES2250360T3 (de)
MX (1) MX236472B (de)
NO (1) NO328803B1 (de)
NZ (1) NZ521137A (de)
RU (1) RU2288215C2 (de)
WO (1) WO2001068582A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO20004844L (no) 2000-09-27 2002-05-10 Thia Medica As Fettsyre analoger for behandling av proliferative hudsykdommer
CA2490121C (en) 2002-06-20 2013-01-08 Ic Vec Limited Modified phospholipids
AU2005209331A1 (en) * 2004-01-30 2005-08-11 Peplin Biolipids Pty Ltd Therapeutic and carrier molecules
RU2388490C2 (ru) * 2004-07-19 2010-05-10 Тиа Медика Ас Композиция, содержащая растительный или рыбий жир, и соединения, содержащие неокисляющиеся структурные элементы жирных кислот
NO324533B1 (no) * 2004-07-19 2007-11-19 Thia Medica As Materiale fremstilt fra en kombinasjon av ikke-β-oksiderbare fettsyreanaloger og et proteinmateriale, samt anvendelse derav.
KR20070054637A (ko) * 2004-07-19 2007-05-29 티아 메디카 에이에스 식물유 및/또는 어유 및 비-산화성 지방산 구성요소를포함하는 조성물
EP2217224B1 (de) 2007-11-09 2019-05-08 Basf As Lipid-verbindungen zur verwendung in kosmetischen produkten, als nahrungsergänzungsmittel oder als medikament
NO20075894L (no) * 2007-11-15 2009-05-18 Thia Medica As Redusert kjonnsmodning i fisk
EP2147910A1 (de) * 2008-07-15 2010-01-27 Pronova BioPharma Norge AS Neue Lipid-Verbindungen
PL2427415T3 (pl) 2009-05-08 2019-09-30 Basf As Wielonienasycone kwasy tłuszczowe do leczenia chorób związanych z dziedziną chorób sercowo-naczyniowych, metabolicznych i zapalnych
RU2402326C1 (ru) * 2009-06-22 2010-10-27 Учреждение Российской академии медицинских наук Дальневосточный научный центр физиологии и патологии дыхания Сибирского отделения Российской академии медицинских наук (ДНЦ ФПД СО РАМН) Способ коррекции инсулинорезистентности при метаболическом синдроме
NZ610705A (en) 2010-11-05 2014-10-31 Pronova Biopharma Norge As Methods of treatment using lipid compounds
KR102213143B1 (ko) 2013-02-28 2021-02-08 바스프 에이에스 지방질 화합물, 트리글리세리드 및 계면활성제를 포함하는 조성물 및 이를 이용하는 방법
EP2968568A2 (de) 2013-03-11 2016-01-20 Life Science Nutrition AS Natürliche lipide mit nicht oxidierbaren fettsäuren
AU2014228387B2 (en) 2013-03-11 2016-09-01 Sciadonics, Inc. Lipid compositions containing bioactive fatty acids
BR112017023164A2 (en) 2015-04-28 2018-07-24 Pronova Biopharma Norge As and method of preventing and / or treating non-alcoholic steatohepatitis in an individual in need thereof
BR112020011431A2 (pt) 2017-12-06 2020-11-24 Basf As derivados de ácido graxo para o tratamento de esteato-hepatite não alcoólica
WO2020251368A1 (en) * 2019-06-11 2020-12-17 Rosi Charni As Liposome formulation

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2210230A1 (de) * 1972-03-03 1973-09-06 Kolmar Laboratories Verwendung bestimmter thioaether als antimikrobielle und zytostatische mittel
BE809894A (nl) 1973-01-30 1974-07-18 Antikleursluierstoffen voor fotografische kleurenmaterialen
JPS5531778B2 (de) * 1973-02-15 1980-08-20
DE3620685A1 (de) 1986-06-20 1987-12-23 Henkel Kgaa Neue mittel zur abdeckung unverletzter und/oder verletzter bereiche menschlicher oder tierischer haut
PT88053B (pt) 1987-07-22 1995-03-01 Roussel Uclaf Processo para a preparacao de biciclo-octanos substituidos
FR2631339B1 (fr) 1988-05-10 1990-11-16 Cird Nouveaux eicosanoides sulfures et leur application en pharmacie et en cosmetique
US5268494A (en) * 1988-05-10 1993-12-07 Centre International De Recherches Dermatologiques C.I.R.D. Sulphur-containing eicosanoides and their application in pharmacy and in cosmetics
GB8813012D0 (en) * 1988-06-02 1988-07-06 Norsk Hydro As Non-b-oxidizable fatty acid analogues to reduce concentration of cholesterol & triglycerides in blood of mammals
JPH0379659A (ja) 1989-08-22 1991-04-04 Mitsubishi Gas Chem Co Inc 光学用成形材料
DE69027423T2 (de) 1989-09-11 1997-02-06 Kao Corp Bleichzusammensetzung
CA2030174C (en) * 1990-01-10 1996-12-24 Anthony H. Cincotta Process for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hypoglycemia in vertebrates
JP3079659B2 (ja) 1991-08-07 2000-08-21 松下電器産業株式会社 車載用空気清浄器
US6602861B1 (en) 1992-04-16 2003-08-05 Research Corporation Technologies, Inc. Acylated phospholipid drugs
US5554646A (en) * 1992-04-29 1996-09-10 Wisconsin Alumni Research Foundation Method for reducing body fat in animals
US5290960A (en) 1993-02-25 1994-03-01 The United States Of America As Represented By The Secretary Of The Navy Diacetylenic phospholipids containing heteroatom near diacetylenic functionality for modulation of microstructure morphology
CN1088058C (zh) * 1994-10-13 2002-07-24 肽技术有限公司 经修饰的多不饱和脂肪酸
NO952796D0 (no) * 1995-07-14 1995-07-14 Rolf Berge Fettsyre analoger med ikkeoksyderbart B-sete, fremstilling og anvendelse i krapeutiske preparater
WO1997038688A1 (en) * 1996-04-12 1997-10-23 Peptide Technology Pty. Limited Methods of treating immunopathologies using polyunsaturated fattyacids
AU3408097A (en) * 1996-06-06 1998-01-05 Ergo Research Corporation Treatment of lipid and glucose metabolism disorders with dopamine and seroto nin agonists
AU7240398A (en) * 1998-05-08 1999-11-29 Rolf Berge Use of non-beta-oxidizable fatty acid analogues for treatment of syndrome-x conditions
JP2002519341A (ja) * 1998-06-29 2002-07-02 パーカー ヒューズ インスティテュート 強力な抗がん剤としてのアルキルケトン類
US6656498B1 (en) 1998-11-25 2003-12-02 Vanderbilt University Cationic liposomes for gene transfer
FR2792312B1 (fr) 1999-04-15 2001-06-08 Oreal Composes (poly)thia-alcynoiques et leurs derives, compositions les comprenant et leur utilisation
AUPQ291499A0 (en) * 1999-09-17 1999-10-07 Women's And Children's Hospital Adelaide Novel nitro and sulphur containing compounds
NO20003591L (no) 2000-07-13 2002-01-14 Thia Medica As Fettsyreanaloger for behandling av kreft
NO20004844L (no) 2000-09-27 2002-05-10 Thia Medica As Fettsyre analoger for behandling av proliferative hudsykdommer
NO20006008L (no) 2000-11-28 2002-05-29 Thia Medica As Fettsyreanaloger for behandling av inflammatoriske og autoimmune sykdommer
US20020188023A1 (en) 2000-12-12 2002-12-12 Michael Jorgensen Compound
GB0118517D0 (en) 2001-07-30 2001-09-19 Mitsubishi Tokyo Pharm Inc Compound
FR2828487B1 (fr) 2001-08-09 2005-05-27 Genfit S A Nouveaux composes derives d'acides gras, preparation et utilisations
CA2490121C (en) 2002-06-20 2013-01-08 Ic Vec Limited Modified phospholipids
KR20070054637A (ko) 2004-07-19 2007-05-29 티아 메디카 에이에스 식물유 및/또는 어유 및 비-산화성 지방산 구성요소를포함하는 조성물

Also Published As

Publication number Publication date
KR100857626B1 (ko) 2008-09-08
DE60113663T2 (de) 2006-07-27
EP1265838A1 (de) 2002-12-18
KR20090108135A (ko) 2009-10-14
US7902399B2 (en) 2011-03-08
NZ521137A (en) 2004-08-27
EP1265838B1 (de) 2005-09-28
JP5122050B2 (ja) 2013-01-16
HK1050182A1 (en) 2003-06-13
NO328803B1 (no) 2010-05-18
NO20001123L (no) 2001-09-04
DK1265838T3 (da) 2006-02-20
RU2002123590A (ru) 2004-02-27
BR0108950A (pt) 2003-01-28
MXPA02008629A (es) 2003-09-22
RU2288215C2 (ru) 2006-11-27
US20040213442A1 (en) 2004-10-28
AU2001237835B2 (en) 2006-03-23
CN1283611C (zh) 2006-11-08
KR20080046747A (ko) 2008-05-27
MX236472B (es) 2006-05-04
CA2401757A1 (en) 2001-09-20
ATE305447T1 (de) 2005-10-15
KR100940373B1 (ko) 2010-02-02
AU3783501A (en) 2001-09-24
CN1419532A (zh) 2003-05-21
ES2250360T3 (es) 2006-04-16
JP2003527364A (ja) 2003-09-16
KR100982228B1 (ko) 2010-09-14
KR20020077931A (ko) 2002-10-14
NO20001123D0 (no) 2000-03-03
CA2401757C (en) 2010-09-14
WO2001068582A1 (en) 2001-09-20
EP1265838B9 (de) 2006-05-10

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