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DE60039998D1 - Pentacyclische taxan-verbindungen - Google Patents

Pentacyclische taxan-verbindungen

Info

Publication number
DE60039998D1
DE60039998D1 DE60039998T DE60039998T DE60039998D1 DE 60039998 D1 DE60039998 D1 DE 60039998D1 DE 60039998 T DE60039998 T DE 60039998T DE 60039998 T DE60039998 T DE 60039998T DE 60039998 D1 DE60039998 D1 DE 60039998D1
Authority
DE
Germany
Prior art keywords
taxan
pentacyclic
compounds
taxan compounds
pentacyclic taxan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60039998T
Other languages
English (en)
Inventor
Soga
Uoto
Takeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Application granted granted Critical
Publication of DE60039998D1 publication Critical patent/DE60039998D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE60039998T 1999-10-15 2000-10-12 Pentacyclische taxan-verbindungen Expired - Lifetime DE60039998D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP29335699 1999-10-15
PCT/JP2000/007087 WO2001027115A1 (en) 1999-10-15 2000-10-12 Pentacyclic taxane compounds

Publications (1)

Publication Number Publication Date
DE60039998D1 true DE60039998D1 (de) 2008-10-02

Family

ID=17793741

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60039998T Expired - Lifetime DE60039998D1 (de) 1999-10-15 2000-10-12 Pentacyclische taxan-verbindungen

Country Status (22)

Country Link
EP (1) EP1221445B1 (de)
JP (1) JP3776799B2 (de)
KR (1) KR100706566B1 (de)
CN (1) CN1203074C (de)
AR (1) AR026026A1 (de)
AT (1) ATE405569T1 (de)
AU (1) AU774787B2 (de)
BR (1) BR0014687A (de)
CA (1) CA2386772C (de)
DE (1) DE60039998D1 (de)
DK (1) DK1221445T3 (de)
ES (1) ES2311473T3 (de)
HK (1) HK1044000B (de)
IL (2) IL149007A0 (de)
MX (1) MXPA02003797A (de)
MY (1) MY125378A (de)
NO (1) NO328418B1 (de)
PT (1) PT1221445E (de)
RU (1) RU2257387C2 (de)
TW (1) TWI225062B (de)
WO (1) WO2001027115A1 (de)
ZA (1) ZA200202696B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1295229C (zh) * 2001-11-29 2007-01-17 第一制药株式会社 紫杉烷衍生物的结晶及其制备方法
TW200533339A (en) 2004-03-16 2005-10-16 Bristol Myers Squibb Co Therapeutic synergy of anti-cancer compounds
CA2565013C (en) 2004-04-30 2013-01-08 Daiichi Pharmaceutical Co., Ltd. Method for producing pentacyclic taxans
WO2007049575A1 (ja) * 2005-10-25 2007-05-03 Daiichi Sankyo Company, Limited アゼチジン環構造を有するタキサン化合物
CN100516067C (zh) * 2006-01-10 2009-07-22 上海恒瑞医药有限公司 具有抗肿瘤活性的紫杉酚衍生物
US8785669B2 (en) 2010-06-30 2014-07-22 Gfv, Llc Taxane compounds, compositions and methods
CN103732229A (zh) 2011-08-02 2014-04-16 安斯泰来制药株式会社 基于药剂的联用的癌症治疗方法
FR2986526A1 (fr) 2012-02-03 2013-08-09 Sanofi Sa Procede de preparation de derives du taxol et certains composes intermediaires
CN104650109B (zh) * 2013-11-22 2019-01-01 江苏天士力帝益药业有限公司 紫杉烷类化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
FR2712289B1 (fr) * 1993-11-08 1996-01-05 Rhone Poulenc Rorer Sa Nouveaux dérivés de taxicine, leur préparation et les compositions pharmaceutiques qui les contiennent.
KR100380875B1 (ko) * 1995-04-28 2003-10-10 다이이찌 세이야꾸 가부시기가이샤 펜타사이클릭화합물
TW527183B (en) * 1996-06-06 2003-04-11 Daiichi Seiyaku Co Drug complex

Also Published As

Publication number Publication date
MY125378A (en) 2006-07-31
KR20020035901A (ko) 2002-05-15
EP1221445A4 (de) 2003-05-28
EP1221445A1 (de) 2002-07-10
ES2311473T3 (es) 2009-02-16
CA2386772A1 (en) 2001-04-19
NO328418B1 (no) 2010-02-15
AU774787B2 (en) 2004-07-08
CN1409714A (zh) 2003-04-09
BR0014687A (pt) 2002-11-19
ATE405569T1 (de) 2008-09-15
MXPA02003797A (es) 2002-12-13
AR026026A1 (es) 2002-12-26
TWI225062B (en) 2004-12-11
JP3776799B2 (ja) 2006-05-17
HK1044000A1 (en) 2002-10-04
IL149007A (en) 2006-12-10
HK1044000B (en) 2008-11-21
RU2257387C2 (ru) 2005-07-27
CN1203074C (zh) 2005-05-25
EP1221445B1 (de) 2008-08-20
NO20021753L (no) 2002-06-12
PT1221445E (pt) 2008-10-08
ZA200202696B (en) 2003-09-23
CA2386772C (en) 2009-01-13
IL149007A0 (en) 2002-11-10
DK1221445T3 (da) 2008-11-24
WO2001027115A1 (en) 2001-04-19
NO20021753D0 (no) 2002-04-12
AU7685100A (en) 2001-04-23
KR100706566B1 (ko) 2007-04-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition