DE60031243D1 - Impfstofformulierung gegen tuberkulose mit monoglyceriden oder fettsäuren als adjuvant - Google Patents
Impfstofformulierung gegen tuberkulose mit monoglyceriden oder fettsäuren als adjuvantInfo
- Publication number
- DE60031243D1 DE60031243D1 DE60031243T DE60031243T DE60031243D1 DE 60031243 D1 DE60031243 D1 DE 60031243D1 DE 60031243 T DE60031243 T DE 60031243T DE 60031243 T DE60031243 T DE 60031243T DE 60031243 D1 DE60031243 D1 DE 60031243D1
- Authority
- DE
- Germany
- Prior art keywords
- sub
- adjuvant
- fatty acids
- monoglycerides
- vaccination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 201000008827 tuberculosis Diseases 0.000 title abstract 3
- 239000002671 adjuvant Substances 0.000 title abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract 2
- 229930195729 fatty acid Natural products 0.000 title abstract 2
- 239000000194 fatty acid Substances 0.000 title abstract 2
- 150000004665 fatty acids Chemical class 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical compound CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 title 1
- 238000002255 vaccination Methods 0.000 title 1
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 abstract 2
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 2
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9900495A SE9900495D0 (sv) | 1999-02-12 | 1999-02-12 | Vaccine composition |
| SE9900495 | 1999-02-12 | ||
| PCT/EP2000/001046 WO2000047225A2 (en) | 1999-02-12 | 2000-02-09 | Tuberculosis vaccine formulation comprising monoglycerides or fatty acids as adjuvant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60031243D1 true DE60031243D1 (de) | 2006-11-23 |
| DE60031243T2 DE60031243T2 (de) | 2007-05-24 |
Family
ID=20414469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60031243T Expired - Lifetime DE60031243T2 (de) | 1999-02-12 | 2000-02-09 | Impfstofformulierung gegen tuberkulose mit monoglyceriden oder fettsäuren als adjuvant |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6936260B1 (de) |
| EP (1) | EP1154792B1 (de) |
| AT (1) | ATE342065T1 (de) |
| AU (1) | AU769390B2 (de) |
| DE (1) | DE60031243T2 (de) |
| DK (1) | DK1154792T3 (de) |
| ES (1) | ES2275495T3 (de) |
| NZ (1) | NZ513130A (de) |
| SE (1) | SE9900495D0 (de) |
| WO (1) | WO2000047225A2 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPR030800A0 (en) * | 2000-09-22 | 2000-10-12 | Pharmalink International Limited | Immunomodulatory preparation |
| DE60226175T2 (de) * | 2001-11-14 | 2009-07-09 | Novavax, Inc. | Mycobakterieller impfstoff |
| CN1602199B (zh) * | 2001-12-11 | 2012-04-04 | 巴斯德研究院 | 用于治疗包含免疫失调的疾病的革兰氏阳性菌制剂 |
| CU23476A1 (es) * | 2004-01-29 | 2009-12-17 | Ct Ingenieria Genetica Biotech | Formulación adyuvante conteniendo una emulsión oleosa con aceite de jojoba |
| JP5159322B2 (ja) * | 2005-01-28 | 2013-03-06 | ノース−ウエスト ユニヴァーシティ | ワクチンの有効性増強のためのアジュバント |
| PT2144626E (pt) * | 2007-04-12 | 2015-03-03 | Lighter Jennifer | Vacina para a tuberculose e processo para o seu uso |
| CN102441162B (zh) * | 2010-10-04 | 2018-07-24 | 免疫产品美国股份有限公司 | 结核病的治疗和预防 |
| KR20140053887A (ko) * | 2011-04-20 | 2014-05-08 | 미코 바이오, 인크. | 면역 반응을 증진시키는 조성물 및 방법 |
| EP2620159A1 (de) * | 2012-01-24 | 2013-07-31 | Institut Pasteur | Verbesserte Krebsbehandlung durch Immuntherapie mit BCG- oder antigenetisch ähnlichen nicht-pathogenen Mykobakterien |
| WO2018006939A1 (en) | 2016-07-05 | 2018-01-11 | Universidad De Zaragoza | Inactivated tuberculosis vaccine |
| US12491216B2 (en) | 2018-12-04 | 2025-12-09 | Neiker—Instituto Vasco De Investigacion Y Desarrollo Agrario, S.A. | Immunostimulant for use against pathogens |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU212924B (en) * | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| WO1993006921A1 (en) * | 1991-10-04 | 1993-04-15 | Gs Biochem Ab | Particles, method of preparing said particles and uses thereof |
| DK17093D0 (da) | 1993-02-15 | 1993-02-15 | Lyfjathroun H F | Farmaceutisk praeparat til topisk administrering af antigener og/eller vacciner til pattedyr via slimhinder |
| ATE318147T1 (de) * | 1996-03-25 | 2006-03-15 | Medarex Inc | Spezifische monoklonale antikörperfür die extrazelluläre domäne von protasta-spezifischem membranantigen |
| SE9602280D0 (sv) | 1996-06-10 | 1996-06-10 | Pharmatrix Ab | Immunstimulerande lipidformulering |
-
1999
- 1999-02-12 SE SE9900495A patent/SE9900495D0/xx unknown
-
2000
- 2000-02-09 AU AU28035/00A patent/AU769390B2/en not_active Ceased
- 2000-02-09 WO PCT/EP2000/001046 patent/WO2000047225A2/en not_active Ceased
- 2000-02-09 EP EP00906305A patent/EP1154792B1/de not_active Expired - Lifetime
- 2000-02-09 AT AT00906305T patent/ATE342065T1/de not_active IP Right Cessation
- 2000-02-09 ES ES00906305T patent/ES2275495T3/es not_active Expired - Lifetime
- 2000-02-09 DE DE60031243T patent/DE60031243T2/de not_active Expired - Lifetime
- 2000-02-09 US US09/926,001 patent/US6936260B1/en not_active Expired - Fee Related
- 2000-02-09 DK DK00906305T patent/DK1154792T3/da active
- 2000-02-09 NZ NZ513130A patent/NZ513130A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000047225A2 (en) | 2000-08-17 |
| AU769390B2 (en) | 2004-01-22 |
| SE9900495D0 (sv) | 1999-02-12 |
| ES2275495T3 (es) | 2007-06-16 |
| WO2000047225A3 (en) | 2000-12-14 |
| AU2803500A (en) | 2000-08-29 |
| ATE342065T1 (de) | 2006-11-15 |
| EP1154792A2 (de) | 2001-11-21 |
| EP1154792B1 (de) | 2006-10-11 |
| US6936260B1 (en) | 2005-08-30 |
| NZ513130A (en) | 2003-01-31 |
| DK1154792T3 (da) | 2007-02-12 |
| DE60031243T2 (de) | 2007-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |