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CZ61893A3 - Cyclopeptides, process of their preparation and their use as medicaments - Google Patents

Cyclopeptides, process of their preparation and their use as medicaments Download PDF

Info

Publication number
CZ61893A3
CZ61893A3 CS93618A CS6189391A CZ61893A3 CZ 61893 A3 CZ61893 A3 CZ 61893A3 CS 93618 A CS93618 A CS 93618A CS 6189391 A CS6189391 A CS 6189391A CZ 61893 A3 CZ61893 A3 CZ 61893A3
Authority
CZ
Czechia
Prior art keywords
arg
ile
gly
phe
ala
Prior art date
Application number
CS93618A
Other languages
Czech (cs)
English (en)
Inventor
Gerd Schnorrenberg
Rainer Palluk
Stefan Heinrichs
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19904032271 external-priority patent/DE4032271A1/de
Priority claimed from DE19904032269 external-priority patent/DE4032269A1/de
Priority claimed from DE19904032268 external-priority patent/DE4032268A1/de
Priority claimed from DE19914117733 external-priority patent/DE4117733A1/de
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of CZ61893A3 publication Critical patent/CZ61893A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C07K14/582—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CS93618A 1990-10-11 1991-10-10 Cyclopeptides, process of their preparation and their use as medicaments CZ61893A3 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19904032271 DE4032271A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19904032269 DE4032269A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19904032268 DE4032268A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19914117733 DE4117733A1 (de) 1991-05-30 1991-05-30 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
PCT/EP1991/001934 WO1992006998A1 (fr) 1990-10-11 1991-10-10 Cyclopeptides, leur procede de production et leur utilisation comme medicaments

Publications (1)

Publication Number Publication Date
CZ61893A3 true CZ61893A3 (en) 1994-01-19

Family

ID=27435038

Family Applications (1)

Application Number Title Priority Date Filing Date
CS93618A CZ61893A3 (en) 1990-10-11 1991-10-10 Cyclopeptides, process of their preparation and their use as medicaments

Country Status (12)

Country Link
EP (1) EP0552238A1 (fr)
JP (1) JPH06501950A (fr)
KR (1) KR930702395A (fr)
AU (1) AU8736691A (fr)
CA (1) CA2089747A1 (fr)
CZ (1) CZ61893A3 (fr)
FI (1) FI931499A0 (fr)
HU (1) HUT63859A (fr)
IE (1) IE913582A1 (fr)
PL (1) PL168456B1 (fr)
SK (1) SK32693A3 (fr)
WO (1) WO1992006998A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846932A (en) * 1993-11-12 1998-12-08 Genentech, Inc. Receptor specific atrial natriuretic peptides
US6525022B1 (en) 1993-11-12 2003-02-25 Genentech, Inc. Receptor specific atrial natriuretic peptides
US5665704A (en) * 1993-11-12 1997-09-09 Genentech, Inc. Receptor specific atrial natriuretic peptides
WO1999067286A2 (fr) * 1998-06-24 1999-12-29 The Rockefeller University Nouveaux peptides de staphylocoques utilises pour des interferences bacteriennes
US6337385B1 (en) 1998-06-24 2002-01-08 The Rockefeller University Staphylococcus peptides for bacterial interference
FR2797689B1 (fr) * 1999-08-16 2003-06-27 Pasteur Sanofi Diagnostics Utilisation de composes synthetiques pour des immunodosages
US6455587B1 (en) * 2000-03-15 2002-09-24 Pharmacor Inc. Amino acid derivatives as HIV aspartyl protease inhibitors
WO2004082629A2 (fr) 2003-03-17 2004-09-30 Albany Molecular Research, Inc. Nouvelles cyclosporines
US7388008B2 (en) 2004-08-02 2008-06-17 Ambrilia Biopharma Inc. Lysine based compounds
US7378391B2 (en) 2004-09-29 2008-05-27 Amr Technology, Inc. Cyclosporin alkyne analogues and their pharmaceutical uses
JP2008514702A (ja) 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド 新規シクロスポリン類似体およびそれらの薬学的使用
US7361636B2 (en) 2004-10-06 2008-04-22 Amr Technology, Inc. Cyclosporin alkynes and their utility as pharmaceutical agents
AU2006319716B2 (en) 2005-11-30 2012-02-02 Taimed Biologics, Inc. Lysine-based prodrugs of aspartyl protease inhibitors and processes for their preparation
JP2009532385A (ja) 2006-03-30 2009-09-10 パラティン・テクノロジーズ・インコーポレーテッド 線状ナトリウム利尿ペプチド構築物
EA016804B1 (ru) 2006-03-30 2012-07-30 Палатин Текнолоджиз, Инк. Циклические конструкты натрийуретических пептидов
US8580746B2 (en) 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
CN102083793A (zh) 2006-09-21 2011-06-01 安布林生物制药公司 蛋白酶抑制剂
PL2118123T3 (pl) 2007-01-31 2016-06-30 Dana Farber Cancer Inst Inc Stabilizowane peptydy p53 i ich zastosowania
KR101525754B1 (ko) 2007-03-28 2015-06-09 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 스티칭된 폴리펩티드
CA2807685C (fr) 2010-08-13 2020-10-06 Aileron Therapeutics, Inc. Macrocycle peptidomimetique derive de p53
TW201806968A (zh) 2011-10-18 2018-03-01 艾利倫治療公司 擬肽巨環化合物
BR112014020103A2 (pt) 2012-02-15 2018-10-09 Aileron Therapeutics, Inc. macrociclos peptidomiméticos
CA2864120A1 (fr) 2012-02-15 2013-08-22 Aileron Therapeutics, Inc. Macrocycles peptidomimetiques reticules par triazole et par thioether
KR20150082307A (ko) 2012-11-01 2015-07-15 에일러론 테라퓨틱스 인코포레이티드 이치환 아미노산 및 이의 제조 및 사용 방법
US20170112896A1 (en) 2014-05-20 2017-04-27 Ohio State Innovation Foundation Small molecule rac or rho inhibitors
SG10201902598VA (en) 2014-09-24 2019-04-29 Aileron Therapeutics Inc Peptidomimetic macrocycles and formulations thereof
MX2017003797A (es) 2014-09-24 2017-06-15 Aileron Therapeutics Inc Macrociclos peptidomimeticos y usos de los mismos.
US10253067B2 (en) 2015-03-20 2019-04-09 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
CN108368161A (zh) 2015-09-10 2018-08-03 艾瑞朗医疗公司 作为mcl-1调节剂的拟肽大环化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337891C (fr) * 1987-12-16 1996-01-02 John Dimaio Derives du facteur natriuretique avec nouveau pontage
US4935492A (en) * 1987-12-24 1990-06-19 California Biotechnology Inc. Cyclic analogs of atrial natriuretic peptides
DK380288D0 (da) * 1988-07-07 1988-07-07 Novo Industri As Hidtil ukendet peptider

Also Published As

Publication number Publication date
AU8736691A (en) 1992-05-20
FI931499A7 (fi) 1993-04-02
FI931499L (fi) 1993-04-02
EP0552238A1 (fr) 1993-07-28
SK32693A3 (en) 1993-09-09
JPH06501950A (ja) 1994-03-03
FI931499A0 (fi) 1993-04-02
CA2089747A1 (fr) 1992-04-12
WO1992006998A1 (fr) 1992-04-30
PL168456B1 (pl) 1996-02-29
IE913582A1 (en) 1992-04-22
HU9301054D0 (en) 1993-07-28
HUT63859A (en) 1993-10-28
KR930702395A (ko) 1993-09-09

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