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CY2017048I1 - Νεες φαρμακευτικες χρησεις των παραγωγων σταυροσπορινης - Google Patents

Νεες φαρμακευτικες χρησεις των παραγωγων σταυροσπορινης

Info

Publication number
CY2017048I1
CY2017048I1 CY2017048C CY2017048C CY2017048I1 CY 2017048 I1 CY2017048 I1 CY 2017048I1 CY 2017048 C CY2017048 C CY 2017048C CY 2017048 C CY2017048 C CY 2017048C CY 2017048 I1 CY2017048 I1 CY 2017048I1
Authority
CY
Cyprus
Prior art keywords
stavrosporine
derivatives
new pharmaceutical
pharmaceutical uses
new
Prior art date
Application number
CY2017048C
Other languages
English (en)
Other versions
CY2017048I2 (el
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33539193&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2017048(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY2017048I2 publication Critical patent/CY2017048I2/el
Publication of CY2017048I1 publication Critical patent/CY2017048I1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/16Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CY2017048C 2003-06-18 2017-12-22 Νεες φαρμακευτικες χρησεις των παραγωγων σταυροσπορινης CY2017048I1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47957503P 2003-06-18 2003-06-18
PCT/EP2004/006562 WO2004112794A2 (en) 2003-06-18 2004-06-17 New pharmaceutical uses of staurosporine derivatives
EP04740016A EP1638574B1 (en) 2003-06-18 2004-06-17 New pharmaceutical uses of staurosporine derivatives

Publications (2)

Publication Number Publication Date
CY2017048I2 CY2017048I2 (el) 2018-09-05
CY2017048I1 true CY2017048I1 (el) 2018-09-05

Family

ID=33539193

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20101100627T CY1110179T1 (el) 2003-06-18 2010-07-06 Νεες φαρμακευτικες χρησεις των παραγωγων σταυροσπορινης
CY2017048C CY2017048I1 (el) 2003-06-18 2017-12-22 Νεες φαρμακευτικες χρησεις των παραγωγων σταυροσπορινης

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20101100627T CY1110179T1 (el) 2003-06-18 2010-07-06 Νεες φαρμακευτικες χρησεις των παραγωγων σταυροσπορινης

Country Status (23)

Country Link
US (2) US8575146B2 (el)
EP (1) EP1638574B1 (el)
JP (2) JP5057780B2 (el)
CN (2) CN100457111C (el)
AT (1) ATE464052T1 (el)
AU (1) AU2004248909B2 (el)
BE (1) BE2017C067I2 (el)
BR (1) BRPI0411563B8 (el)
CA (2) CA2527703C (el)
CY (2) CY1110179T1 (el)
DE (1) DE602004026578D1 (el)
DK (1) DK1638574T3 (el)
ES (1) ES2344700T3 (el)
FR (1) FR17C1063I2 (el)
HU (1) HUS000503I2 (el)
LU (1) LUC00055I9 (el)
MX (1) MXPA05013722A (el)
NL (1) NL300917I2 (el)
PL (1) PL1638574T3 (el)
PT (1) PT1638574E (el)
SI (1) SI1638574T1 (el)
TW (1) TWI324604B (el)
WO (1) WO2004112794A2 (el)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI324604B (en) * 2003-06-18 2010-05-11 Novartis Ag New use of staurosporine derivatives
US20060014165A1 (en) * 2003-07-14 2006-01-19 Decode Genetics Ehf. Methods of diagnosis and treatment for asthma and other respiratory diseases based on haplotype association
JP4762150B2 (ja) 2003-11-18 2011-08-31 ノバルティス アーゲー Kitの変異体の阻害剤
WO2005115385A1 (en) * 2004-05-24 2005-12-08 Ab Science Use of c-kit inhibitors for treating acne
US20090054358A1 (en) * 2004-07-19 2009-02-26 The John Hopkins University Flt3 inhibitors for immune suppression
MX2007001155A (es) * 2004-07-29 2007-08-14 Creabilis Therapeutics Spa Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1.
GB0419159D0 (en) * 2004-08-27 2004-09-29 Novartis Ag Organic compounds
PL1879585T3 (pl) * 2005-05-02 2013-08-30 Novartis Ag Zastosowanie pochodnych pirymidyloaminobenzamidowych do leczenia mastocytozy układowej
RU2429848C2 (ru) * 2005-07-20 2011-09-27 Петер ФАЛЕНТ Композиции для лечения системного мастоцитоза
AU2006313724B2 (en) * 2005-11-14 2010-12-23 Universitat Zurich Staurosporine derivatives for use in alveolar rhabdomyosarcoma
WO2009092442A1 (en) * 2008-01-23 2009-07-30 Universidad De Barcelona Treatment of portal hypertension and related conditions by combined inhibition of the vegf and pdgf signalling pathways
EP2662078A1 (en) * 2010-11-10 2013-11-13 National Jewish Health Methods to Treat Allergic Conditions
US20210401859A1 (en) 2018-11-01 2021-12-30 Syros Pharmaceuticals, Inc. Methods of treating cancer in biomarker-identified patients with non-covalent inhibitors of cyclin-dependent kinase 7 (cdk7)
US11325978B2 (en) * 2018-11-06 2022-05-10 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Compositions and methods for treating beta-globinopathies
US11839619B2 (en) * 2019-09-16 2023-12-12 The Regents Of The University Of California Methods for treatment of pediatric systemic mastocytosis
KR102805013B1 (ko) * 2022-03-15 2025-05-09 국립해양생물자원관 스트렙토마이세스 속 snc087 균주 또는 이로부터 분리한 스타우로스포린을 유효성분으로 포함하는 비용종 예방 또는 치료용 약학 조성물

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639455A (en) * 1984-10-02 1987-01-27 Key Pharmaceuticals, Inc. Means of aiding in the prevention of sudden infant death syndrome
JPH0826037B2 (ja) 1987-01-22 1996-03-13 協和醗酵工業株式会社 生理活性物質k−252の誘導体
US5093330A (en) * 1987-06-15 1992-03-03 Ciba-Geigy Corporation Staurosporine derivatives substituted at methylamino nitrogen
CA2046801C (en) 1990-08-07 2002-02-26 Peter D. Davis Substituted pyrroles
DK0518468T3 (da) * 1991-05-09 2000-01-31 Neurim Pharma 1991 Melatoninholdige sammensætninger
AR004480A1 (es) 1995-04-06 1998-12-16 Amico Derin C D Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
WO1997049406A1 (en) 1996-06-25 1997-12-31 Cephalon, Inc. Use of k-252a derivative for the treatment of peripheral or central nerve disorders, and cytokine overproduction
US6093740A (en) 1997-04-30 2000-07-25 Eli Lilly And Company Therapeutic treatment for skin disorders
WO1999062537A1 (en) * 1998-06-04 1999-12-09 The Rockefeller University Methods and agents for modulating the immune response and inflammation involving monocyte and dendritic cell membrane proteins
GB9903547D0 (en) * 1999-02-16 1999-04-07 Novartis Ag Organic compounds
ATE301661T1 (de) * 2000-12-08 2005-08-15 Ortho Mcneil Pharm Inc Makroheterocyclische verbindungen als kinase inhibitoren
GB0108606D0 (en) * 2001-04-05 2001-05-23 Novartis Ag Organic compounds
WO2003002109A2 (en) * 2001-06-29 2003-01-09 Ab Science Use of tyrosine kinase inhibitors for treating autoimmune diseases
US20030091974A1 (en) * 2001-06-29 2003-05-15 Alain Moussy Method for screening compounds capable of depleting mast cells
EP1441737B1 (en) * 2001-10-30 2006-08-09 Novartis AG Staurosporine derivatives as inhibitors of flt3 receptor tyrosine kinase activity
US6998391B2 (en) * 2002-02-07 2006-02-14 Supergen.Inc. Method for treating diseases associated with abnormal kinase activity
CA2522712A1 (en) * 2003-04-18 2004-10-28 Kyowa Hakko Kogyo Co., Ltd. Nerve regenerating drug
WO2004093910A1 (ja) 2003-04-22 2004-11-04 Astellas Pharma Inc. PPARδアゴニストによる脳神経変性疾患治療剤
TWI324604B (en) * 2003-06-18 2010-05-11 Novartis Ag New use of staurosporine derivatives
JP4762150B2 (ja) 2003-11-18 2011-08-31 ノバルティス アーゲー Kitの変異体の阻害剤

Also Published As

Publication number Publication date
PL1638574T3 (pl) 2010-09-30
LUC00055I1 (el) 2017-12-14
EP1638574A2 (en) 2006-03-29
LUC00055I9 (el) 2022-11-09
US20070299049A1 (en) 2007-12-27
EP1638574B1 (en) 2010-04-14
AU2004248909B2 (en) 2008-05-08
FR17C1063I2 (fr) 2019-05-03
DK1638574T3 (da) 2010-08-02
HK1095519A1 (zh) 2007-05-11
ES2344700T3 (es) 2010-09-03
LUC00055I2 (el) 2018-02-21
HUS000503I2 (hu) 2021-03-29
CN101164539A (zh) 2008-04-23
JP2006527727A (ja) 2006-12-07
TWI324604B (en) 2010-05-11
AU2004248909A1 (en) 2004-12-29
MXPA05013722A (es) 2006-03-08
ATE464052T1 (de) 2010-04-15
BRPI0411563B1 (pt) 2019-09-24
TW200512213A (en) 2005-04-01
DE602004026578D1 (de) 2010-05-27
NL300917I2 (nl) 2018-01-09
WO2004112794A3 (en) 2005-06-16
CY1110179T1 (el) 2015-01-14
JP5057780B2 (ja) 2012-10-24
US20130289018A1 (en) 2013-10-31
NL300917I1 (nl) 2017-12-12
CA2785950A1 (en) 2004-12-29
CA2527703C (en) 2012-10-23
CA2527703A1 (en) 2004-12-29
BRPI0411563B8 (pt) 2021-05-25
CN1805749A (zh) 2006-07-19
CY2017048I2 (el) 2018-09-05
PT1638574E (pt) 2010-07-14
BE2017C067I2 (el) 2023-08-09
HUS1700053I1 (hu) 2018-01-29
JP2012144572A (ja) 2012-08-02
WO2004112794A2 (en) 2004-12-29
SI1638574T1 (sl) 2010-08-31
CN100457111C (zh) 2009-02-04
US8575146B2 (en) 2013-11-05
FR17C1063I1 (el) 2018-02-16
BRPI0411563A (pt) 2006-08-01

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