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CY1119077T1 - Παραγωγα πυραζολυλαμινοπυριδινης χρησιμα ως αναστολεις κινασων - Google Patents

Παραγωγα πυραζολυλαμινοπυριδινης χρησιμα ως αναστολεις κινασων

Info

Publication number
CY1119077T1
CY1119077T1 CY20151101071T CY151101071T CY1119077T1 CY 1119077 T1 CY1119077 T1 CY 1119077T1 CY 20151101071 T CY20151101071 T CY 20151101071T CY 151101071 T CY151101071 T CY 151101071T CY 1119077 T1 CY1119077 T1 CY 1119077T1
Authority
CY
Cyprus
Prior art keywords
pyrazylylamin
chinase
pyridene
producers
suspensions
Prior art date
Application number
CY20151101071T
Other languages
English (en)
Inventor
Audrey Davies
Michelle Lamb
Paul Lyne
Peter Mohr
Bin Wang
Tao Wang
Dingwei Yu
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CY1119077T1 publication Critical patent/CY1119077T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Αυτή η εφεύρεση σχετίζεται με καινοφανείς ενώσεις έχουσες τον χημικό τύπο (I), και με τις φαρμακευτικές συνθέσεις αυτών και με τις μεθόδους χρήσης αυτών. Αυτές οι καινοφανείς ενώσεις παρέχουν μια αγωγή για καρκίνο.
CY20151101071T 2005-02-04 2015-11-26 Παραγωγα πυραζολυλαμινοπυριδινης χρησιμα ως αναστολεις κινασων CY1119077T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65005305P 2005-02-04 2005-02-04
US65332905P 2005-02-16 2005-02-16
US72163305P 2005-09-29 2005-09-29
EP06701619A EP1846394B1 (en) 2005-02-04 2006-02-01 Pyrazolylaminopyridine derivatives useful as kinase inhibitors

Publications (1)

Publication Number Publication Date
CY1119077T1 true CY1119077T1 (el) 2018-01-10

Family

ID=36177856

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20121100025T CY1115078T1 (el) 2005-02-04 2012-01-11 Παραγωγα πυραζολοαμινοπυριδινης χρησιμα ως αναστολεις της κινασης
CY20151101071T CY1119077T1 (el) 2005-02-04 2015-11-26 Παραγωγα πυραζολυλαμινοπυριδινης χρησιμα ως αναστολεις κινασων

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20121100025T CY1115078T1 (el) 2005-02-04 2012-01-11 Παραγωγα πυραζολοαμινοπυριδινης χρησιμα ως αναστολεις της κινασης

Country Status (29)

Country Link
US (2) US8324252B2 (el)
EP (2) EP1846394B1 (el)
JP (1) JP5139084B2 (el)
KR (1) KR101302945B1 (el)
CN (1) CN101155800B (el)
AR (1) AR056184A1 (el)
AT (1) ATE530545T1 (el)
AU (1) AU2006210710B2 (el)
BR (1) BRPI0606793A8 (el)
CA (1) CA2595834C (el)
CY (2) CY1115078T1 (el)
DK (2) DK2383268T3 (el)
ES (2) ES2555063T3 (el)
HR (1) HRP20110962T1 (el)
HU (1) HUE025671T2 (el)
IL (1) IL184674A (el)
ME (1) ME02645B (el)
MX (1) MX2007009437A (el)
MY (1) MY149512A (el)
NO (1) NO341112B1 (el)
NZ (1) NZ561145A (el)
PL (2) PL2383268T3 (el)
PT (2) PT1846394E (el)
RS (1) RS52061B (el)
SA (1) SA06270007B1 (el)
SI (2) SI1846394T1 (el)
TW (1) TWI370127B (el)
UY (1) UY29360A1 (el)
WO (1) WO2006082392A1 (el)

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Also Published As

Publication number Publication date
PT2383268E (pt) 2015-12-21
JP2008528664A (ja) 2008-07-31
RS52061B (sr) 2012-04-30
MX2007009437A (es) 2007-08-16
AR056184A1 (es) 2007-09-26
DK1846394T3 (da) 2012-01-16
US20080139561A1 (en) 2008-06-12
HK1163677A1 (en) 2012-09-14
SI1846394T1 (sl) 2012-06-29
EP1846394A1 (en) 2007-10-24
BRPI0606793A2 (pt) 2009-12-01
HUE025671T2 (en) 2016-04-28
CN101155800B (zh) 2012-05-23
EP2383268B1 (en) 2015-09-02
CY1115078T1 (el) 2016-12-14
DK2383268T3 (en) 2015-09-14
SI2383268T1 (sl) 2016-02-29
IL184674A0 (en) 2007-12-03
IL184674A (en) 2012-07-31
EP1846394B1 (en) 2011-10-26
HK1114374A1 (en) 2008-10-31
MY149512A (en) 2013-09-13
WO2006082392A1 (en) 2006-08-10
JP5139084B2 (ja) 2013-02-06
PL1846394T3 (pl) 2012-04-30
UY29360A1 (es) 2006-10-02
US8835465B2 (en) 2014-09-16
AU2006210710B2 (en) 2009-12-10
KR20070107107A (ko) 2007-11-06
ES2375735T3 (es) 2012-03-05
CA2595834A1 (en) 2006-08-10
SA06270007B1 (ar) 2010-11-22
CA2595834C (en) 2013-04-30
HRP20110962T1 (hr) 2012-01-31
EP2383268A1 (en) 2011-11-02
ES2555063T3 (es) 2015-12-28
AU2006210710A1 (en) 2006-08-10
NO20073791L (no) 2007-08-30
ME02645B (me) 2012-04-30
US8324252B2 (en) 2012-12-04
KR101302945B1 (ko) 2013-09-06
US20130090358A1 (en) 2013-04-11
NO341112B1 (no) 2017-08-28
TWI370127B (en) 2012-08-11
ATE530545T1 (de) 2011-11-15
PT1846394E (pt) 2012-01-05
BRPI0606793A8 (pt) 2018-03-13
NZ561145A (en) 2011-02-25
CN101155800A (zh) 2008-04-02
PL2383268T3 (pl) 2016-02-29

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