CY1111750T1 - Νευροτροφικοι παραγοντες - Google Patents
Νευροτροφικοι παραγοντεςInfo
- Publication number
- CY1111750T1 CY1111750T1 CY20111100765T CY111100765T CY1111750T1 CY 1111750 T1 CY1111750 T1 CY 1111750T1 CY 20111100765 T CY20111100765 T CY 20111100765T CY 111100765 T CY111100765 T CY 111100765T CY 1111750 T1 CY1111750 T1 CY 1111750T1
- Authority
- CY
- Cyprus
- Prior art keywords
- neurotrophic factors
- neublastin
- polypeptides
- methods
- antibodies
- Prior art date
Links
- 108010025020 Nerve Growth Factor Proteins 0.000 title 1
- 102000007072 Nerve Growth Factors Human genes 0.000 title 1
- 239000003900 neurotrophic factor Substances 0.000 title 1
- 102100026376 Artemin Human genes 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Abstract
Η εφεύρεση αφορά σε πολυπεπτίδια νευροτροφικού παράγοντα νευροβλαστίνης, νουκλεϊνικά οξέα που κωδικοποιούν τα πολυπεπτίδια νευροβλαστίνης, και αντισώματα που προσδένονται ειδικά σε πολυπεπτίδια νευροβλαστίνης, καθώς επίσης και σε μεθόδους παρασκευής και μεθόδους χρήσης αυτών.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/804,615 US20020055467A1 (en) | 1998-07-06 | 2001-03-12 | Novel neurotrophic factors |
| EP07120461A EP1930439B1 (en) | 2001-03-12 | 2002-03-12 | Neurotrophic factors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1111750T1 true CY1111750T1 (el) | 2015-10-07 |
Family
ID=25189406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20111100765T CY1111750T1 (el) | 2001-03-12 | 2011-08-10 | Νευροτροφικοι παραγοντες |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20020055467A1 (el) |
| EP (2) | EP1373503B1 (el) |
| JP (2) | JP3738008B2 (el) |
| CN (1) | CN1268744C (el) |
| AT (2) | ATE509103T1 (el) |
| AU (1) | AU2002240943B2 (el) |
| CA (1) | CA2440767C (el) |
| CY (1) | CY1111750T1 (el) |
| DE (1) | DE60223511T2 (el) |
| DK (2) | DK1373503T3 (el) |
| ES (2) | ES2296899T3 (el) |
| NZ (1) | NZ528790A (el) |
| PT (2) | PT1373503E (el) |
| SI (2) | SI1373503T1 (el) |
| WO (1) | WO2002072826A2 (el) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
| HRP20010036B1 (hr) * | 1998-07-14 | 2010-06-30 | Janssen Pharmaceutica N.V. | Neurotrofni faktor rasta |
| BR0116749A (pt) * | 2000-12-22 | 2006-11-28 | Genentech Inc | usos de artemina ou seu agonista e artigo manufaturado |
| US7442370B2 (en) * | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
| US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
| WO2002078730A2 (en) * | 2001-03-28 | 2002-10-10 | Biogen, Inc. | Use of neublastin polypeptides for treating neuropathic pain |
| AU2002359786A1 (en) * | 2001-12-19 | 2003-07-09 | Hiroaki Mizukami | Adeno-associated virus-mediated delivery of gdnf to skeletal muscles |
| JP4571776B2 (ja) * | 2002-11-05 | 2010-10-27 | Jx日鉱日石エネルギー株式会社 | 潤滑油組成物 |
| RS52910B (sr) * | 2003-01-31 | 2014-02-28 | Biogen Idec Ma Inc. | Polimerni konjugati mutiranog neublastina |
| JP4742030B2 (ja) * | 2003-04-18 | 2011-08-10 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | ポリマーが結合したグリコシル化ニューブラスチン |
| DE602004019524D1 (de) | 2003-06-10 | 2009-04-02 | Nsgene As | Verbesserte sezernierung von neublastin |
| US7598059B2 (en) * | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
| KR20060095568A (ko) | 2003-10-20 | 2006-08-31 | 엔에스진 에이/에스 | 파킨슨병의 생체내 유전자 요법 |
| PT1786454E (pt) * | 2004-08-19 | 2010-08-18 | Biogen Idec Inc | Variantes de neublastina |
| CN101123978B (zh) * | 2004-08-19 | 2012-12-12 | 比奥根艾迪克Ma公司 | 神经胚素变体 |
| US20080260702A1 (en) * | 2005-10-11 | 2008-10-23 | Jesper Roland Jorgensen | Treatment of Retinopathies Using Gfra3 Agonists |
| TWI501774B (zh) * | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
| US20100056440A1 (en) * | 2006-03-01 | 2010-03-04 | Biogen Idec Ma Inc. | Compositions and methods for administering gdnf ligand family proteins |
| TWI445544B (zh) | 2007-05-01 | 2014-07-21 | Biogen Idec Inc | 增進血管形成之組合物及方法 |
| US20110135648A1 (en) * | 2007-08-08 | 2011-06-09 | Biogen Idec Ma Inc. | Anti-neublastin antibodies and uses thereof |
| WO2009045813A1 (en) * | 2007-10-01 | 2009-04-09 | Vgx Pharmaceuticals, Inc. | Materials and methods for the delivery of biomolecules to cells of an organ |
| KR101886029B1 (ko) * | 2010-10-01 | 2018-08-07 | 호바 세라퓨틱스 에이피에스 | 무해자극통증, 통각과민증, 자발통증 및 헛통증의 치료를 위한 메테오린의 용도 |
| US20190381138A1 (en) * | 2018-05-17 | 2019-12-19 | Helixmith Co., Ltd. | Treatment of neuropathic pain associated with chemotherapy-induced peripheral neuropathy |
| JP7504367B2 (ja) | 2021-05-18 | 2024-06-24 | 株式会社Lttバイオファーマ | 抗癌剤の投与に伴う障害を治療又は予防するための医薬組成物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184200B1 (en) * | 1995-09-28 | 2001-02-06 | Amgen Inc. | Truncated glial cell line-derived neurotrophic factor |
| ATE335003T1 (de) | 1996-05-08 | 2006-08-15 | Biogen Idec Inc | Ret-ligand 3 (retl3), um neurales und renales wachstum zu stimulieren |
| US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
| US6284540B1 (en) * | 1998-09-29 | 2001-09-04 | Washington University | Artemin, a novel neurotrophic factor |
| WO2000034475A2 (en) * | 1998-12-09 | 2000-06-15 | Amgen Inc. | Grnf4, a gdnf-related neurotrophic factor |
| ES2287020T3 (es) * | 1999-06-02 | 2007-12-16 | Genentech, Inc. | Procedimiento y composiciones para inhibir el crecimiento de celulas neoplasicas. |
-
2001
- 2001-03-12 US US09/804,615 patent/US20020055467A1/en not_active Abandoned
-
2002
- 2002-03-12 DK DK02706759T patent/DK1373503T3/da active
- 2002-03-12 SI SI200230656T patent/SI1373503T1/sl unknown
- 2002-03-12 DK DK07120461.4T patent/DK1930439T3/da active
- 2002-03-12 NZ NZ528790A patent/NZ528790A/en not_active IP Right Cessation
- 2002-03-12 ES ES02706759T patent/ES2296899T3/es not_active Expired - Lifetime
- 2002-03-12 AT AT07120461T patent/ATE509103T1/de active
- 2002-03-12 CA CA2440767A patent/CA2440767C/en not_active Expired - Fee Related
- 2002-03-12 AT AT02706759T patent/ATE378353T1/de active
- 2002-03-12 PT PT02706759T patent/PT1373503E/pt unknown
- 2002-03-12 JP JP2002571881A patent/JP3738008B2/ja not_active Expired - Fee Related
- 2002-03-12 DE DE60223511T patent/DE60223511T2/de not_active Expired - Lifetime
- 2002-03-12 EP EP02706759A patent/EP1373503B1/en not_active Expired - Lifetime
- 2002-03-12 WO PCT/EP2002/002691 patent/WO2002072826A2/en not_active Ceased
- 2002-03-12 AU AU2002240943A patent/AU2002240943B2/en not_active Ceased
- 2002-03-12 ES ES07120461T patent/ES2366610T3/es not_active Expired - Lifetime
- 2002-03-12 PT PT07120461T patent/PT1930439E/pt unknown
- 2002-03-12 CN CNB028097858A patent/CN1268744C/zh not_active Expired - Fee Related
- 2002-03-12 EP EP07120461A patent/EP1930439B1/en not_active Expired - Lifetime
- 2002-03-12 SI SI200230954T patent/SI1930439T1/sl unknown
-
2005
- 2005-02-02 JP JP2005027109A patent/JP2005198656A/ja not_active Withdrawn
-
2011
- 2011-08-10 CY CY20111100765T patent/CY1111750T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI1373503T1 (sl) | 2008-04-30 |
| ES2366610T3 (es) | 2011-10-21 |
| EP1373503A2 (en) | 2004-01-02 |
| AU2002240943B2 (en) | 2007-05-10 |
| CA2440767C (en) | 2012-05-29 |
| EP1373503B1 (en) | 2007-11-14 |
| EP1930439B1 (en) | 2011-05-11 |
| WO2002072826A3 (en) | 2003-04-10 |
| ATE509103T1 (de) | 2011-05-15 |
| AU2002240943A2 (en) | 2002-09-24 |
| CA2440767A1 (en) | 2002-09-19 |
| US20020055467A1 (en) | 2002-05-09 |
| DE60223511D1 (de) | 2007-12-27 |
| PT1930439E (pt) | 2011-07-25 |
| PT1373503E (pt) | 2008-02-26 |
| ATE378353T1 (de) | 2007-11-15 |
| NZ528790A (en) | 2004-06-25 |
| DK1930439T3 (da) | 2011-08-29 |
| CN1509333A (zh) | 2004-06-30 |
| DK1373503T3 (da) | 2008-03-25 |
| DE60223511T2 (de) | 2008-10-23 |
| EP1930439A1 (en) | 2008-06-11 |
| ES2296899T3 (es) | 2008-05-01 |
| HK1120556A1 (en) | 2009-04-03 |
| JP2005198656A (ja) | 2005-07-28 |
| CN1268744C (zh) | 2006-08-09 |
| JP2004531242A (ja) | 2004-10-14 |
| WO2002072826A2 (en) | 2002-09-19 |
| SI1930439T1 (sl) | 2011-09-30 |
| JP3738008B2 (ja) | 2006-01-25 |
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