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CY1110842T1 - Φαρμακευτικες συνθεσεις για τη συντονισμενη διανομη των μσαφ - Google Patents

Φαρμακευτικες συνθεσεις για τη συντονισμενη διανομη των μσαφ

Info

Publication number
CY1110842T1
CY1110842T1 CY20101100948T CY101100948T CY1110842T1 CY 1110842 T1 CY1110842 T1 CY 1110842T1 CY 20101100948 T CY20101100948 T CY 20101100948T CY 101100948 T CY101100948 T CY 101100948T CY 1110842 T1 CY1110842 T1 CY 1110842T1
Authority
CY
Cyprus
Prior art keywords
coordinated
nsaid
pharmaceutical compositions
dosage form
release
Prior art date
Application number
CY20101100948T
Other languages
English (en)
Inventor
John R Plachetka
Original Assignee
Pozen, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23134063&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110842(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pozen, Inc. filed Critical Pozen, Inc.
Publication of CY1110842T1 publication Critical patent/CY1110842T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε μορφές δόσεως φαρμάκου που απελευθερώνουν έναν παράγοντα ο οποίος αυξάνει το pΗ της γαστρεντερικής οδού ενός ασθενούς, ακολουθούμενο από ένα μη στεροειδές αντιφλεγμονώδες φάρμακο. Η μορφή δόσεως σχεδιάζεται ώστε το ΜΣΑΦ να μην απελευθερώνεται μέχρι το ενδογαστρικό pΗ να έχει αυξηθεί σε ασφαλές επίπεδο. Η εφεύρεση περικλείει επίσης μεθόδους αγωγής των ασθενών δια της χορηγήσεως αυτής της μορφής μοναδιαίας δόσεως του συνδυασμού συντονισμένης απελευθερώσεως, γαστροπροστασίας, αντιαρθριτικού/αναλγητικού για να επιτευχθεί ανακούφιση από το άλγος και τα συμπτώματα με μειωμένο κίνδυνο αναπτύξεως γαστρεντερικής βλάβης όπως έλκη, διαβρώσεις και αιμορραγίες.
CY20101100948T 2001-06-01 2010-10-21 Φαρμακευτικες συνθεσεις για τη συντονισμενη διανομη των μσαφ CY1110842T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29458801P 2001-06-01 2001-06-01
EP02734602.2A EP1411900B2 (en) 2001-06-01 2002-05-31 PHARMACEUTICAL COMPOSITIONS FOR THE COORDINATED DELIVERY OF NSAIDs

Publications (1)

Publication Number Publication Date
CY1110842T1 true CY1110842T1 (el) 2015-06-10

Family

ID=23134063

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100948T CY1110842T1 (el) 2001-06-01 2010-10-21 Φαρμακευτικες συνθεσεις για τη συντονισμενη διανομη των μσαφ

Country Status (18)

Country Link
US (1) US6926907B2 (el)
EP (3) EP2163241A1 (el)
JP (1) JP4756823B2 (el)
AT (1) ATE474559T1 (el)
AU (3) AU2002305758B2 (el)
BE (1) BE2011C016I2 (el)
CA (1) CA2449098C (el)
CY (1) CY1110842T1 (el)
DE (1) DE60237087D1 (el)
DK (1) DK1411900T4 (el)
EA (1) EA006398B1 (el)
ES (1) ES2348710T5 (el)
IL (2) IL159129A0 (el)
LU (1) LU91858I2 (el)
MX (1) MXPA03011017A (el)
NO (2) NO333836B1 (el)
PT (1) PT1411900E (el)
WO (1) WO2002098352A2 (el)

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