[go: up one dir, main page]

CY1110049T1 - Ευρεως χρησιμοποιουμενη διαδικασια για την ταυτοποιηση των ρυθμιστων των συνδεδεμενων με g-πρωτεϊνη υποδοχεων - Google Patents

Ευρεως χρησιμοποιουμενη διαδικασια για την ταυτοποιηση των ρυθμιστων των συνδεδεμενων με g-πρωτεϊνη υποδοχεων

Info

Publication number
CY1110049T1
CY1110049T1 CY20101100467T CY101100467T CY1110049T1 CY 1110049 T1 CY1110049 T1 CY 1110049T1 CY 20101100467 T CY20101100467 T CY 20101100467T CY 101100467 T CY101100467 T CY 101100467T CY 1110049 T1 CY1110049 T1 CY 1110049T1
Authority
CY
Cyprus
Prior art keywords
pathway
identifying
protein
protein related
gpcr
Prior art date
Application number
CY20101100467T
Other languages
English (en)
Inventor
Evi Kostenis
Original Assignee
Sanofi-Aventis Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis Deutschland Gmbh filed Critical Sanofi-Aventis Deutschland Gmbh
Publication of CY1110049T1 publication Critical patent/CY1110049T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)

Abstract

Η εφεύρεση αφορά σε μια ευρέως χρησιμοποιούμενη διαδικασία για την ταυτοποίηση χημικών ενώσεων, οι οποίες ρυθμίζουν τους συνδεδεμένους με G-πρωτεΐνη υποδοχείς, μέσω νέων υβριδικών G-πρωτεΐνών με πολύ ευρεία εξειδίκευση υποδοχέων και πολύ υψηλή έκφραση καθώς και σε χημικές ενώσεις, που μπορούν να ταυτοποιηθούν μέσω μιας τέτοιας διαδικασίας.
CY20101100467T 2000-07-08 2010-05-27 Ευρεως χρησιμοποιουμενη διαδικασια για την ταυτοποιηση των ρυθμιστων των συνδεδεμενων με g-πρωτεϊνη υποδοχεων CY1110049T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10033353A DE10033353A1 (de) 2000-07-08 2000-07-08 Breit einsetzbares Verfahren zur Identifizierung von Modulatoren von G-Protein gekoppelten Rezeptoren
EP01951650A EP1319022B1 (de) 2000-07-08 2001-07-05 Breit einsetzbares verfahren zur identifizierung von modulatoren von g-protein gekoppelten rezeptoren

Publications (1)

Publication Number Publication Date
CY1110049T1 true CY1110049T1 (el) 2015-01-14

Family

ID=7648325

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100467T CY1110049T1 (el) 2000-07-08 2010-05-27 Ευρεως χρησιμοποιουμενη διαδικασια για την ταυτοποιηση των ρυθμιστων των συνδεδεμενων με g-πρωτεϊνη υποδοχεων

Country Status (19)

Country Link
US (2) US20040002109A9 (el)
EP (1) EP1319022B1 (el)
JP (1) JP4991081B2 (el)
KR (1) KR100922701B1 (el)
AT (1) ATE462721T1 (el)
AU (2) AU7252201A (el)
BR (1) BR0112300B1 (el)
CA (1) CA2415460C (el)
CY (1) CY1110049T1 (el)
DE (2) DE10033353A1 (el)
DK (1) DK1319022T3 (el)
ES (1) ES2342453T3 (el)
IL (2) IL153818A0 (el)
MX (1) MXPA02012641A (el)
NO (2) NO330684B1 (el)
NZ (1) NZ523480A (el)
PT (1) PT1319022E (el)
WO (1) WO2002004665A2 (el)
ZA (1) ZA200300707B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002036622A2 (en) * 2000-10-30 2002-05-10 Senomyx, Inc. GαqPROETIN VARIANTS AND THEIR USE IN THE ANALYSIS AND DISCOVERY OF AGONISTS AND ANTAGONISTS OF CHEMOSENSORY RECEPTORS
US20050112701A1 (en) * 2003-09-11 2005-05-26 Aventis Pharma Deutschland Gmbh Test system for the identification of APJ receptor ligands
EP1520861A1 (en) * 2003-09-11 2005-04-06 Aventis Pharma Deutschland GmbH Test system for the identification of APJ receptor ligands
DE102007002260A1 (de) 2007-01-16 2008-07-31 Sanofi-Aventis Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms
ES2637805T3 (es) 2008-05-05 2017-10-17 Sanofi Derivados de ácido ciclopentanocarboxílico fusionados sustituidos por acilamino y su uso como productos farmacéuticos
AR079022A1 (es) 2009-11-02 2011-12-21 Sanofi Aventis Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion
EP2862574A1 (en) 2013-10-15 2015-04-22 Sanofi {4-[5-(3-chloro-phenoxy)-oxazolo[5,4 d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-acetic acid for use in the prevention or treatment of acute kidney injury
CN109946451B (zh) * 2019-04-16 2022-05-20 浙江诺迦生物科技有限公司 一种基于细胞内游离钙离子浓度变化效应的大麻素类活性物质的检测方法及其检测试剂盒
CN109946450B (zh) * 2019-04-16 2022-04-19 浙江诺迦生物科技有限公司 一种基于细胞内游离钙离子浓度变化效应的阿片类活性物质的检测方法及其检测试剂盒

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6004808A (en) * 1996-06-21 1999-12-21 Aurora Biosciences Corporation Promiscuous G-protein compositions and their use
US6383761B2 (en) * 1997-07-28 2002-05-07 The Regents Of The University Of California Methods and compositions for identifying modulators of G-protein-coupled receptors

Also Published As

Publication number Publication date
AU2001272522B2 (en) 2007-05-31
EP1319022B1 (de) 2010-03-31
NO330684B1 (no) 2011-06-06
NZ523480A (en) 2008-04-30
BR0112300B1 (pt) 2014-01-21
IL153818A (en) 2010-05-31
DE50115416D1 (de) 2010-05-12
NO20030068D0 (no) 2003-01-07
DK1319022T3 (da) 2010-07-26
US20050255531A1 (en) 2005-11-17
KR100922701B1 (ko) 2009-10-22
ATE462721T1 (de) 2010-04-15
JP2004502463A (ja) 2004-01-29
CA2415460A1 (en) 2002-01-17
NO20101390L (no) 2003-01-07
US20040002109A9 (en) 2004-01-01
WO2002004665A2 (de) 2002-01-17
ES2342453T3 (es) 2010-07-07
US7378252B2 (en) 2008-05-27
MXPA02012641A (es) 2003-04-25
PT1319022E (pt) 2010-06-11
JP4991081B2 (ja) 2012-08-01
NO20030068L (no) 2003-01-07
DE10033353A1 (de) 2002-01-24
CA2415460C (en) 2011-05-10
IL153818A0 (en) 2003-07-31
AU7252201A (en) 2002-01-21
KR20030021246A (ko) 2003-03-12
BR0112300A (pt) 2004-07-27
EP1319022A2 (de) 2003-06-18
WO2002004665A3 (de) 2002-12-19
US20020127601A1 (en) 2002-09-12
ZA200300707B (en) 2004-04-15

Similar Documents

Publication Publication Date Title
CY1110049T1 (el) Ευρεως χρησιμοποιουμενη διαδικασια για την ταυτοποιηση των ρυθμιστων των συνδεδεμενων με g-πρωτεϊνη υποδοχεων
CY1108998T1 (el) Πρωτεϊνες που δεσμευονται με οστεοπροτεγερινη και υποδοχεις
DK169724B1 (da) Fremgangsmåde til fremstilling af et polypeptidfragment af faktor VIII:C, DNA-sekvens, som koder herfor, og ekstrachromosomalt element indeholdende en sådan DNA-sekvens
Hanai et al. Protein footprinting by the combined use of reversible and irreversible lysine modifications.
NO961115D0 (no) Humane metabotrope glutamatreseptorsubtyper (HMR4, HMR6, HMR7) og relaterte DNA forbindelser
Wu et al. Autonomous subdomains in protein folding
Righetti et al. Isoelectric focusing in immobilized pH gradients: an update
Dunten et al. Recognition of modified forms of ribonuclease A by the ubiquitin system
NO20010362L (no) Nukleinsyrer kodende for proteiner som er involvert i sensorisk transduksjon
DE69434661D1 (de) An die periplasmatische Membran gebundenes System zur Ermittlung von Protein-Protein Interaktionen
DE69735716D1 (de) Kappa/mu ähnliche proteintyrosinphosphatase, proteintyrosinphosphatase lambda
DE69837811D1 (de) Menschlicher lysophosphatidsäure rezeptor und dessen verwendung
CA2279881A1 (en) A method of identifying modulators of cell surface membrane receptors useful in the treatment of disease
James et al. Protein microsequencing with post-column fluorescent phenylisothiocyanate analogues
Bausserman et al. NH2-terminal analysis of four of the polymorphic forms of human serum amyloid A proteins
US5677422A (en) Method for making a polypeptide derivative
DE69813476D1 (de) G-protein-gekoppelter rezeptor mit selektiver affinität für atp
Wang et al. Reconstructed protein arrays from 3D HPLC/tandem mass spectrometry and 2D gels: complementary approaches to Porphyromonas gingivalis protein expression
ATE121421T1 (de) Hemmung von migration von zellen mit hilfe von synthetischen peptiden.
Yuasa et al. A new α1-antitrypsin allele PI* Poki: Isoelectric focusing with immobilized pH gradients as a tool for identification of PI variants
Babila et al. Rat pineal Gsa, Gia and Goa: relative abundance and development
Rusconi et al. Characterization of the chicken telokin heterogeneity by time-of-flight mass spectrometry
Nikiforovich et al. Biologically active conformation of tuftsin
Law et al. Association of a Lower Molecular Weight Protein to the μ‐Opioid Receptor Demonstrated by 125I‐β‐Endorphin Cross‐Linking Studies
Dunn Quantitative amino acid analysis