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CY1106365T1 - Συνδυασμος ενος αναστολεα pde και ενος ανταγωνιστη υποδοχεων λευκοτριενιου - Google Patents

Συνδυασμος ενος αναστολεα pde και ενος ανταγωνιστη υποδοχεων λευκοτριενιου

Info

Publication number
CY1106365T1
CY1106365T1 CY20071100329T CY071100329T CY1106365T1 CY 1106365 T1 CY1106365 T1 CY 1106365T1 CY 20071100329 T CY20071100329 T CY 20071100329T CY 071100329 T CY071100329 T CY 071100329T CY 1106365 T1 CY1106365 T1 CY 1106365T1
Authority
CY
Cyprus
Prior art keywords
combination
leukotriene receptor
receptor antagonist
pde inhibitor
leukotriene
Prior art date
Application number
CY20071100329T
Other languages
English (en)
Inventor
Rolf Beume
Christian Weimar
Stefan-Lutz Wollin
Daniela Bundschuh
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of CY1106365T1 publication Critical patent/CY1106365T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Η εφεύρεση σχετίζεται με τη συνδυασμένη χορήγηση αναστολέων PDE4 ή PDE3/4 και ανταγωνιστών υποδοχέων λευκοτριενίου για τη θεραπεία των νόσων των αναπνευστικών οδών.
CY20071100329T 2001-09-19 2007-03-09 Συνδυασμος ενος αναστολεα pde και ενος ανταγωνιστη υποδοχεων λευκοτριενιου CY1106365T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01000474 2001-09-19
PCT/EP2002/010423 WO2003024488A2 (en) 2001-09-19 2002-09-17 Combination of a pde inhibitor and a leukotriene receptor antagonist
EP02798730A EP1429843B1 (en) 2001-09-19 2002-09-17 Combination of a pde inhibitor and a leukotriene receptor antagonist

Publications (1)

Publication Number Publication Date
CY1106365T1 true CY1106365T1 (el) 2011-10-12

Family

ID=8176066

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100329T CY1106365T1 (el) 2001-09-19 2007-03-09 Συνδυασμος ενος αναστολεα pde και ενος ανταγωνιστη υποδοχεων λευκοτριενιου

Country Status (25)

Country Link
US (1) US20050014762A1 (el)
EP (1) EP1429843B1 (el)
JP (1) JP2005505570A (el)
KR (1) KR20040044946A (el)
CN (1) CN100346831C (el)
AT (1) ATE349243T1 (el)
BR (1) BR0212582A (el)
CA (1) CA2460442A1 (el)
CO (1) CO5560584A2 (el)
CY (1) CY1106365T1 (el)
DE (1) DE60217139T2 (el)
DK (1) DK1429843T3 (el)
EA (1) EA007736B1 (el)
ES (1) ES2279004T3 (el)
HU (1) HUP0500078A3 (el)
IL (2) IL160272A0 (el)
MA (1) MA27136A1 (el)
MX (1) MXPA04002560A (el)
NO (1) NO331885B1 (el)
NZ (1) NZ532279A (el)
PL (1) PL205927B1 (el)
PT (1) PT1429843E (el)
SI (1) SI1429843T1 (el)
WO (1) WO2003024488A2 (el)
ZA (1) ZA200402653B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0719518D0 (en) * 2007-10-05 2007-11-14 Therapeutics Ltd E Therapy
RU2470639C2 (ru) * 2007-10-25 2012-12-27 Мерк Фросст Кэнада Лтд. Композиции для ингаляции, содержащие кислоту монтелукаст и ингибитор pde-4 или ингаляционный кортикостероид
WO2012168907A1 (en) 2011-06-10 2012-12-13 Glenmark Pharmaceuticals Sa Pharmaceutical composition comprising revamilast and montelukast or zafirlukast
WO2014012954A1 (en) 2012-07-18 2014-01-23 Takeda Gmbh Treatment of partly controlled or uncontrolled severe asthma
MD20150071A2 (ro) 2013-02-19 2016-02-29 Pfizer Inc. Compuşi azabenzimidazolici ca inhibitori ai PDE4 izoenzimelor pentru tratamentul tulburărilor SNC şi altor afecţiuni
WO2015063669A1 (en) 2013-10-30 2015-05-07 Wockhardt Limited Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof
JP2017503814A (ja) 2014-01-22 2017-02-02 タケダ ゲー・エム・ベー・ハーＴａｋｅｄａ ＧｍｂＨ 部分的コントロール状態の重症喘息またはコントロール不良状態の重症喘息のｐｄｅ４インヒビターを用いた（およびロイコトリエン調節薬と組み合わせて用いた）治療
US10131669B2 (en) 2014-07-24 2018-11-20 Pfizer Inc. Pyrazolopyrimidine compounds
HUE044040T2 (hu) 2014-08-06 2019-09-30 Pfizer Imidazopiridazin vegyületek

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY121142A (en) * 1999-02-23 2005-12-30 Smithkline Beecham Corp Controlled release formulation for treating copd
TR200909479T2 (tr) * 1999-08-21 2012-02-21 Nycomed Gmbh Sinerjistik kombinasyon.
MY134008A (en) * 1999-12-22 2007-11-30 Merck Frosst Canada Inc Subtituted 8-arylquinoline phospohodiestrase-4 inhibitors
BR0107964A (pt) * 2000-01-31 2002-10-29 Pfizer Prod Inc Derivados de nicotinamida benzofundida com heterociclica úteis como inibidores seletivos de isozimas pde4
MY123585A (en) * 2000-03-23 2006-05-31 Merck Canada Inc Tri-aryl-substituted-ethane pde4 inhibitors.
WO2001090076A1 (en) * 2000-05-25 2001-11-29 Merck Frosst Canada & Co. Fluoroalkoxy-substituted benzamide dichloropyridinyl n-oxide pde4 inhibitor

Also Published As

Publication number Publication date
JP2005505570A (ja) 2005-02-24
MXPA04002560A (es) 2004-05-31
PT1429843E (pt) 2007-03-30
HK1066752A1 (en) 2005-04-01
NO20041595L (no) 2004-06-16
IL160272A0 (en) 2004-07-25
CN100346831C (zh) 2007-11-07
KR20040044946A (ko) 2004-05-31
ES2279004T3 (es) 2007-08-16
DE60217139T2 (de) 2007-10-04
EA200400416A1 (ru) 2004-12-30
US20050014762A1 (en) 2005-01-20
HUP0500078A2 (hu) 2005-04-28
IL160272A (en) 2008-03-20
HUP0500078A3 (en) 2010-07-28
WO2003024488A2 (en) 2003-03-27
ATE349243T1 (de) 2007-01-15
BR0212582A (pt) 2004-10-13
EA007736B1 (ru) 2006-12-29
WO2003024488A3 (en) 2003-09-04
MA27136A1 (fr) 2005-01-03
DK1429843T3 (da) 2007-04-30
ZA200402653B (en) 2005-02-14
PL367414A1 (en) 2005-02-21
EP1429843A2 (en) 2004-06-23
CA2460442A1 (en) 2003-03-27
DE60217139D1 (de) 2007-02-08
EP1429843B1 (en) 2006-12-27
CO5560584A2 (es) 2005-09-30
NO331885B1 (no) 2012-04-30
NZ532279A (en) 2006-02-24
PL205927B1 (pl) 2010-06-30
SI1429843T1 (sl) 2007-06-30
CN1655846A (zh) 2005-08-17

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