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CU20130124A7 - Derivados de tieno [2,3-d] pirimidina y su uso para el tratamiento de la arritmia - Google Patents

Derivados de tieno [2,3-d] pirimidina y su uso para el tratamiento de la arritmia

Info

Publication number
CU20130124A7
CU20130124A7 CU2013000124A CU20130124A CU20130124A7 CU 20130124 A7 CU20130124 A7 CU 20130124A7 CU 2013000124 A CU2013000124 A CU 2013000124A CU 20130124 A CU20130124 A CU 20130124A CU 20130124 A7 CU20130124 A7 CU 20130124A7
Authority
CU
Cuba
Prior art keywords
treatment
arritmia
tieno
pyrimidine
derivatives
Prior art date
Application number
CU2013000124A
Other languages
English (en)
Other versions
CU24173B1 (es
Inventor
Derek Edward John
John Ford
Original Assignee
Xention Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44071904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CU20130124(A7) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xention Ltd filed Critical Xention Ltd
Publication of CU20130124A7 publication Critical patent/CU20130124A7/es
Publication of CU24173B1 publication Critical patent/CU24173B1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compuestos de tienopiridimidina que son inhibidores de canal de potasio. Composiciones farmacéuticas que comprenden los compuestos y su uso en el tratamiento de arritmia.
CUP2013000124A 2011-04-01 2012-03-29 Compuestos derivados de tieno [2,3-d] pirimidina para el tratamiento de la arritmia CU24173B1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1105659.5A GB201105659D0 (en) 2011-04-01 2011-04-01 Compounds
PCT/GB2012/050710 WO2012131379A1 (en) 2011-04-01 2012-03-29 Thieno [2, 3 -d] pyrimidine derivatives and their use to treat arrhythmia

Publications (2)

Publication Number Publication Date
CU20130124A7 true CU20130124A7 (es) 2014-01-29
CU24173B1 CU24173B1 (es) 2016-04-25

Family

ID=44071904

Family Applications (1)

Application Number Title Priority Date Filing Date
CUP2013000124A CU24173B1 (es) 2011-04-01 2012-03-29 Compuestos derivados de tieno [2,3-d] pirimidina para el tratamiento de la arritmia

Country Status (42)

Country Link
US (1) US9249155B2 (es)
EP (1) EP2694518B1 (es)
JP (1) JP5826374B2 (es)
KR (1) KR20140023332A (es)
CN (1) CN103492392B (es)
AP (1) AP2013007198A0 (es)
AR (1) AR088735A1 (es)
AU (1) AU2012235882B2 (es)
BR (1) BR112013025236A2 (es)
CA (1) CA2831493A1 (es)
CL (1) CL2013002789A1 (es)
CO (1) CO6801756A2 (es)
CR (1) CR20130488A (es)
CU (1) CU24173B1 (es)
CY (1) CY1117025T1 (es)
DK (1) DK2694518T3 (es)
EA (1) EA201301111A1 (es)
EC (1) ECSP13012988A (es)
ES (1) ES2558563T3 (es)
GB (1) GB201105659D0 (es)
GT (1) GT201300225A (es)
HR (1) HRP20151340T1 (es)
HU (1) HUE028438T2 (es)
IL (1) IL228555A0 (es)
MA (1) MA35064B1 (es)
ME (1) ME02314B (es)
MX (1) MX335937B (es)
NI (1) NI201300100A (es)
PE (1) PE20141021A1 (es)
PH (1) PH12013501952A1 (es)
PL (1) PL2694518T3 (es)
PT (1) PT2694518E (es)
RS (1) RS54458B1 (es)
RU (1) RU2013148627A (es)
SG (1) SG193578A1 (es)
SI (1) SI2694518T1 (es)
SM (1) SMT201500322B (es)
TN (1) TN2013000377A1 (es)
TW (1) TWI516265B (es)
UA (1) UA110131C2 (es)
WO (1) WO2012131379A1 (es)
ZA (1) ZA201307085B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2922858A4 (en) * 2012-11-20 2016-06-15 Univ Mcgill THIENOPYRIMIDININHIBITORS OF FARNESYL AND / OR GERANYL GERANYL PYROPHOSPHATE SYNTHASE
AU2016378723B2 (en) 2015-12-22 2021-09-30 SHY Therapeutics LLC Compounds for the treatment of cancer and inflammatory disease
CN106727587A (zh) * 2016-11-28 2017-05-31 李娜 一种治疗心律失常的药物组合物
MA49458A (fr) 2017-06-21 2020-04-29 SHY Therapeutics LLC Composés interagissant avec la superfamille ras destinés à être utilisés dans le traitement de cancers, de maladies inflammatoires, de rasopathies et de maladies fibrotiques
EP3898609A1 (en) 2018-12-19 2021-10-27 Shy Therapeutics LLC Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease

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Also Published As

Publication number Publication date
US20140206703A1 (en) 2014-07-24
AR088735A1 (es) 2014-07-02
HK1193096A1 (zh) 2014-09-12
BR112013025236A2 (pt) 2019-09-24
SI2694518T1 (sl) 2016-02-29
CY1117025T1 (el) 2017-04-05
HRP20151340T1 (hr) 2016-02-26
MX2013011301A (es) 2014-04-16
SMT201500322B (it) 2016-02-25
CR20130488A (es) 2013-12-06
NZ615621A (en) 2015-01-30
SG193578A1 (en) 2013-10-30
RS54458B1 (sr) 2016-06-30
ME02314B (me) 2016-06-20
PH12013501952A1 (en) 2018-04-11
US9249155B2 (en) 2016-02-02
GT201300225A (es) 2014-12-30
KR20140023332A (ko) 2014-02-26
TWI516265B (zh) 2016-01-11
MA35064B1 (fr) 2014-04-03
HUE028438T2 (en) 2017-02-28
WO2012131379A1 (en) 2012-10-04
CN103492392A (zh) 2014-01-01
AU2012235882B2 (en) 2015-08-06
CL2013002789A1 (es) 2014-07-18
CN103492392B (zh) 2015-11-25
ECSP13012988A (es) 2013-12-31
IL228555A0 (en) 2013-12-31
AP2013007198A0 (en) 2013-10-31
ZA201307085B (en) 2015-04-29
HK1193806A1 (zh) 2014-10-03
CA2831493A1 (en) 2012-10-04
JP5826374B2 (ja) 2015-12-02
MX335937B (es) 2016-01-04
GB201105659D0 (en) 2011-05-18
EA201301111A1 (ru) 2014-02-28
NI201300100A (es) 2014-01-07
EP2694518A1 (en) 2014-02-12
AU2012235882A1 (en) 2013-05-02
PT2694518E (pt) 2016-02-05
ES2558563T3 (es) 2016-02-05
TW201244720A (en) 2012-11-16
UA110131C2 (ru) 2015-11-25
PL2694518T3 (pl) 2016-03-31
DK2694518T3 (en) 2015-11-09
CU24173B1 (es) 2016-04-25
PE20141021A1 (es) 2014-08-30
RU2013148627A (ru) 2015-05-10
TN2013000377A1 (en) 2015-01-20
EP2694518B1 (en) 2015-10-07
JP2014509637A (ja) 2014-04-21
CO6801756A2 (es) 2013-11-29

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