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MX2015011514A - Compuestos de heteroarilo y sus usos. - Google Patents

Compuestos de heteroarilo y sus usos.

Info

Publication number
MX2015011514A
MX2015011514A MX2015011514A MX2015011514A MX2015011514A MX 2015011514 A MX2015011514 A MX 2015011514A MX 2015011514 A MX2015011514 A MX 2015011514A MX 2015011514 A MX2015011514 A MX 2015011514A MX 2015011514 A MX2015011514 A MX 2015011514A
Authority
MX
Mexico
Prior art keywords
compounds
heteroarilo
methods
pharmaceutically acceptable
protein kinase
Prior art date
Application number
MX2015011514A
Other languages
English (en)
Other versions
MX374558B (es
Inventor
C Petter Russell
Niu Deqiang
Mazdiyasni Hormoz
Harvey Darren
Munson Mark
Zhu Zhendong
John Mcdonald Joseph
Singh Juswinder
Akullian D'agostino Laura
Tjin Tham Sjin Robert
Liu Haibo
Barrague Matthieu
Gross Alexander
Scholte Andrew
Maniar Sachin
Original Assignee
Celgene Avilomics Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Avilomics Res Inc filed Critical Celgene Avilomics Res Inc
Publication of MX2015011514A publication Critical patent/MX2015011514A/es
Publication of MX374558B publication Critical patent/MX374558B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/80—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Epidemiology (AREA)

Abstract

La presente invención proporciona compuestos útiles como inhibidores de proteínas cinasas, composiciones farmacéuticamente aceptables de los compuestos y métodos de uso de los compuestos.
MX2015011514A 2013-03-15 2014-03-14 Compuestos de heteroarilo y sus usos. MX374558B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361793113P 2013-03-15 2013-03-15
EP14305361 2014-03-13
PCT/US2014/029270 WO2014144737A1 (en) 2013-03-15 2014-03-14 Heteroaryl compounds and uses thereof

Publications (2)

Publication Number Publication Date
MX2015011514A true MX2015011514A (es) 2016-08-11
MX374558B MX374558B (es) 2025-03-06

Family

ID=50390019

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015011514A MX374558B (es) 2013-03-15 2014-03-14 Compuestos de heteroarilo y sus usos.

Country Status (13)

Country Link
US (1) US9663524B2 (es)
EP (1) EP2968337B1 (es)
JP (1) JP6576325B2 (es)
KR (1) KR102219695B1 (es)
CN (2) CN111793068A (es)
AU (1) AU2014228746B2 (es)
BR (1) BR112015022191A8 (es)
EA (1) EA036160B1 (es)
MA (1) MA38393B1 (es)
MX (1) MX374558B (es)
PE (1) PE20151776A1 (es)
SG (1) SG11201507478VA (es)
WO (1) WO2014144737A1 (es)

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MA38393A3 (fr) 2018-05-31
EP2968337B1 (en) 2021-07-21
EA201591420A1 (ru) 2016-02-29
CN111793068A (zh) 2020-10-20
US9663524B2 (en) 2017-05-30
AU2014228746B2 (en) 2018-08-30
MA38393B1 (fr) 2018-11-30
KR102219695B1 (ko) 2021-02-25
US20160046634A1 (en) 2016-02-18
CN105307657B (zh) 2020-07-10
JP2016519673A (ja) 2016-07-07
KR20150131237A (ko) 2015-11-24
CN105307657A (zh) 2016-02-03
WO2014144737A1 (en) 2014-09-18
MX374558B (es) 2025-03-06
EA036160B1 (ru) 2020-10-08
EP2968337A4 (en) 2016-10-19
JP6576325B2 (ja) 2019-09-18
EP2968337A1 (en) 2016-01-20
BR112015022191A2 (pt) 2017-10-10
PE20151776A1 (es) 2015-12-11
BR112015022191A8 (pt) 2018-01-23

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