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CO6491066A2 - Metodo quimico para esterilizacion sexual y eliminacion de libido en mamiferos machos - Google Patents

Metodo quimico para esterilizacion sexual y eliminacion de libido en mamiferos machos

Info

Publication number
CO6491066A2
CO6491066A2 CO12008129A CO12008129A CO6491066A2 CO 6491066 A2 CO6491066 A2 CO 6491066A2 CO 12008129 A CO12008129 A CO 12008129A CO 12008129 A CO12008129 A CO 12008129A CO 6491066 A2 CO6491066 A2 CO 6491066A2
Authority
CO
Colombia
Prior art keywords
libido
elimination
active ingredients
male mammals
sterilization
Prior art date
Application number
CO12008129A
Other languages
English (en)
Inventor
Marcelo Vivacqua
Original Assignee
Marcelo Vivacqua
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marcelo Vivacqua filed Critical Marcelo Vivacqua
Publication of CO6491066A2 publication Critical patent/CO6491066A2/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Un método químico para esterilización sexual y eliminación de libido en mamíferos machos se indica para lograr la esterilización biológica de mamíferos machos talescomo bovinos, ovejas, cabras, equinos, cerdos, perros, gatos, y humanos. La invención consiste en una solución acuosa estéril que contiene un principio esclerosante activo (ácido láctico) y una enzima (papaína). La enzima causa digestión del tejido del testículo, intensificando el efecto necrosante del ácido y causando que actúe más rápido y más eficientemente. La asociación de estos dos principios activos provoca una reacción inflamatoria aguda con una resolución rápida caracterizada por fibrosis del órgano. Este efecto conduce a la pérdida de las funciones gametogénicas y androgénicas, y causa esterilidad y eliminación de libido, respectivamente. El proceso de esterilización biológico se puede llevar a cabo fácilmente y no requiere tratamientos adicionales, requiriendo menos manejo de los animales, con menos estrés y ganancia de peso incrementada. El proceso no es doloroso ya sea durante o después de la administración, debido a la lesión de las terminaciones nerviosas del testículo en el momento de la aplicación, y al hecho de que el número más grande de estructuras sensibles está localizado en el saco escrotal. La carne del ganado así tratado no requiere para el consumo un período de espera entre la aplicación y el sacrificio, puesto que los principios activos biológicos se pueden metabolizar fácilmente por el organismo del animal. Este método ya se ha utilizado exitosamente en más de 3,000 animales, y es el único método disponible hoy en día en el cual se utilizan principios activos biológicos naturalmente disponibles.
CO12008129A 2009-07-28 2012-01-20 Metodo quimico para esterilizacion sexual y eliminacion de libido en mamiferos machos CO6491066A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0902699-1A BRPI0902699A2 (pt) 2009-07-28 2009-07-28 método quìmico para esterilização sexual e eliminação da libido em mamìferos do sexo masculino

Publications (1)

Publication Number Publication Date
CO6491066A2 true CO6491066A2 (es) 2012-07-31

Family

ID=43528649

Family Applications (1)

Application Number Title Priority Date Filing Date
CO12008129A CO6491066A2 (es) 2009-07-28 2012-01-20 Metodo quimico para esterilizacion sexual y eliminacion de libido en mamiferos machos

Country Status (14)

Country Link
US (1) US20120156188A1 (es)
EP (1) EP2460532A4 (es)
JP (1) JP2013500273A (es)
KR (1) KR20120052355A (es)
CN (1) CN102497878A (es)
AU (1) AU2010278687A1 (es)
BR (1) BRPI0902699A2 (es)
CA (1) CA2768404A1 (es)
CO (1) CO6491066A2 (es)
MX (1) MX2012000503A (es)
NZ (1) NZ597924A (es)
PH (1) PH12012500162A1 (es)
RU (1) RU2012106488A (es)
WO (1) WO2011011843A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101360830B1 (ko) 2013-11-21 2014-02-11 (주)나비바이오텍 젖산을 함유한 동물의 난소 기능 불활 조성물
EA026326B1 (ru) * 2014-05-23 2017-03-31 Елена Владимировна Кухар Препарат для химической кастрации бычков
RU2568364C1 (ru) * 2014-06-26 2015-11-20 Государственное Научное Учреждение Научно-исследовательский институт ветеринарии Восточной Сибири Россельхозакадемии Способ для кастрации самцов сельскохозяйственных животных
KR102249104B1 (ko) 2019-04-30 2021-05-07 (주)인벤티지랩 데슬로렐린을 포함하는 서방성 마이크로 입자 및 이의 제조 방법
KR20230124229A (ko) 2022-02-18 2023-08-25 (주)인벤티지랩 데슬로렐린을 포함하는 서방성 주사용 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3122440A (en) * 1961-05-02 1964-02-25 Hodges Res & Dev Co Processes of tenderizing meat using ante-mortem enzyme injection and post-mortem water injection
US4339438A (en) * 1976-01-23 1982-07-13 The Curators Of The University Of Missouri Injectable male animal sterilant for selectively controlling the function of testes
US4156427A (en) * 1976-01-23 1979-05-29 The Curators Of The University Of Missouri Injectable male animal sterilant for selectively controlling the function of testes
US4356189A (en) * 1979-04-13 1982-10-26 Philips, Roxane, Inc. Chemical castration
US5164181A (en) * 1992-01-14 1992-11-17 Robert E. Hopkins, Ii, D.V.M., Inc. Enzyme castration of animals
AU729978B2 (en) * 1997-03-21 2001-02-22 Snow Brand Milk Products Co., Ltd. Iron-partial hydrolyzates of casein complexes and processes for preparation thereof
CA2240079A1 (en) * 1998-07-20 2000-01-20 Cyril Gallant Method for preparing a stuffed lobster product incorporating protease enzyme and vacuum extracted meat and roe from head-shells of raw lobster
RU2198669C2 (ru) * 2000-12-27 2003-02-20 Галочкин Владимир Анатольевич Способ энзимостерилизации животных

Also Published As

Publication number Publication date
JP2013500273A (ja) 2013-01-07
RU2012106488A (ru) 2013-09-10
EP2460532A1 (en) 2012-06-06
KR20120052355A (ko) 2012-05-23
WO2011011843A1 (pt) 2011-02-03
NZ597924A (en) 2012-12-21
MX2012000503A (es) 2012-08-03
CN102497878A (zh) 2012-06-13
US20120156188A1 (en) 2012-06-21
EP2460532A4 (en) 2013-05-15
BRPI0902699A2 (pt) 2011-04-12
AU2010278687A1 (en) 2012-02-23
CA2768404A1 (en) 2011-02-03
PH12012500162A1 (en) 2011-02-03

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