CO5700711A2 - Composiciones farmaceuticas de liberacion controlada y exten dida que comprenden polimeros cargados - Google Patents
Composiciones farmaceuticas de liberacion controlada y exten dida que comprenden polimeros cargadosInfo
- Publication number
- CO5700711A2 CO5700711A2 CO05047639A CO05047639A CO5700711A2 CO 5700711 A2 CO5700711 A2 CO 5700711A2 CO 05047639 A CO05047639 A CO 05047639A CO 05047639 A CO05047639 A CO 05047639A CO 5700711 A2 CO5700711 A2 CO 5700711A2
- Authority
- CO
- Colombia
- Prior art keywords
- composition
- polymer
- treating agent
- agent
- anionic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
1.- Una composición farmacéutica bioadhesiva que comprende un agente tratante iónico y un polímero iónico, en donde el polímero es suficientemente ionizado para suministrar un ión con el agente tratamiento para posibilitarle a la composición liberar el agente tratante de una manera controlada durante un periodo extendido de tiempo, y en donde la composición no requiere un sistema de emulsión para administrar el agente tratante.2.- La composición de la reivindicación 1, en donde el polímero es aniónico.3.- La composición de la reivindicación 1, en donde el polímero es catiónico, y la composición además incluyeun agente bioadhesivo.4.- La composición de la reivindicación 2, en donde el agente tratante es aniónico, y la composición además comprende un agente complejante catiónico que forma un complejo con el agente tratante, cuyo complejo se une al polímero aniónico.5.- La composición de la reivindicación 4, en donde el polímero es suficientemente ionizado para unirse con el complejo de agente tratante así corno también suministrar bioadhesión de la composición.6.- La composición de la reivindicación 2, en donde el polímero es suficientemente ionizado para suministrar bioadhesión.7.- La composición de la reivindicación 6, en donde el polímero es un polímero de ácido policarboxílico reticulado bioadhesivo, inchable con agua, pero insoluble en agua.8.- La composición de la reivindicación 7, en donde el polímero comprende policarbofilo.9.- La composición de la reivindicación 1, en donde el agente tratante es liberado durante un periodo de al menos aproximadamente 6 horas.10.- La composición de la reivindicación 2, en donde el agente tratante es liberado durante un periodo de al menos 12 horas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/278,912 US20030114394A1 (en) | 2001-10-29 | 2002-10-24 | Vaginally administered anti-dysrhythmic agents for treating pelvic pain |
| US43850103P | 2003-01-08 | 2003-01-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5700711A2 true CO5700711A2 (es) | 2006-11-30 |
Family
ID=32179474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO05047639A CO5700711A2 (es) | 2002-10-24 | 2005-05-17 | Composiciones farmaceuticas de liberacion controlada y exten dida que comprenden polimeros cargados |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1556015B1 (es) |
| JP (1) | JP5204374B2 (es) |
| KR (1) | KR20050083802A (es) |
| CN (2) | CN101327326A (es) |
| AR (1) | AR039464A1 (es) |
| AU (1) | AU2003233066B2 (es) |
| BR (1) | BR0315576A (es) |
| CA (1) | CA2503383C (es) |
| CO (1) | CO5700711A2 (es) |
| ES (1) | ES2618300T3 (es) |
| HR (1) | HRP20050448A2 (es) |
| MA (1) | MA27493A1 (es) |
| ME (2) | MEP34108A (es) |
| MX (1) | MXPA05004330A (es) |
| NO (1) | NO20052480L (es) |
| NZ (1) | NZ539512A (es) |
| PE (2) | PE20040323A1 (es) |
| PL (1) | PL376537A1 (es) |
| RS (1) | RS20050321A (es) |
| RU (2) | RU2366410C2 (es) |
| TW (1) | TW200406223A (es) |
| WO (1) | WO2004037229A1 (es) |
| ZA (1) | ZA200503133B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080007358A (ko) * | 2005-05-10 | 2008-01-18 | 노파르티스 아게 | 변형 방출형 팜시클로비르 제약 조성물 |
| WO2017130208A1 (en) * | 2016-01-29 | 2017-08-03 | Faheem Hyder Pottoo | Triple drug combination for treatment of status epilepticus and/or partial seizures and/or partial seizures with associated neurological disorders |
| CN119074731A (zh) * | 2024-09-20 | 2024-12-06 | 湖南师范大学 | 盐酸达克罗宁在预防雌性小鼠下丘脑-垂体-卵巢轴损伤中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU565354B2 (en) * | 1983-11-14 | 1987-09-10 | Bio-Mimetics Inc. | Bioadhesive compositions and methods of treatment therewith |
| DK0431719T3 (da) * | 1989-10-31 | 1995-02-27 | Columbia Lab Inc | Vaginalt vævsbefugtende præparat |
| IL114589A (en) * | 1990-11-21 | 1999-12-22 | Roussel Uclaf | Intermediates for the preparation of erythromycin derivatives |
| US5578315A (en) * | 1993-12-01 | 1996-11-26 | Rutgers, The State University Of New Jersey | Mucosal adhesive device for long-acting delivery of pharmaceutical combinations in oral cavity |
| CA2161684C (en) * | 1994-03-07 | 2010-11-09 | Larry R. Wilson | Bioactive and/or targeted dendrimer conjugates |
| US5667492A (en) * | 1994-10-07 | 1997-09-16 | Columbia Laboratories, Inc. | Use and composition of an anti-sexually transmitted diseases formulation |
| US6197327B1 (en) * | 1997-06-11 | 2001-03-06 | Umd, Inc. | Device and method for treatment of dysmenorrhea |
| US6624200B2 (en) * | 1998-08-25 | 2003-09-23 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| DE69819748T2 (de) * | 1997-09-12 | 2004-09-30 | Columbia Laboratories (Bermuda) Ltd. | Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen |
| US6248358B1 (en) * | 1998-08-25 | 2001-06-19 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets and methods of making and using the same |
| UA74168C2 (uk) * | 1999-10-05 | 2005-11-15 | Коламбіа Леборетеріс (Бермуда) Лімітед | Лікування ендометріозу або безпліддя, або покращення плідності та застосування бета-адренергічного агоніста для виробництва лікарського засобу |
-
2002
- 2002-10-28 CN CNA2008100962684A patent/CN101327326A/zh active Pending
-
2003
- 2003-04-24 TW TW092109642A patent/TW200406223A/zh unknown
- 2003-04-25 NZ NZ539512A patent/NZ539512A/en not_active IP Right Cessation
- 2003-04-25 PE PE2003000414A patent/PE20040323A1/es not_active Application Discontinuation
- 2003-04-25 EP EP03727364.6A patent/EP1556015B1/en not_active Expired - Lifetime
- 2003-04-25 KR KR1020057006990A patent/KR20050083802A/ko not_active Ceased
- 2003-04-25 PE PE2008001302A patent/PE20081613A1/es not_active Application Discontinuation
- 2003-04-25 WO PCT/EP2003/004316 patent/WO2004037229A1/en not_active Ceased
- 2003-04-25 HR HR20050448A patent/HRP20050448A2/hr not_active Application Discontinuation
- 2003-04-25 RU RU2005115574/15A patent/RU2366410C2/ru not_active IP Right Cessation
- 2003-04-25 BR BR0315576-5A patent/BR0315576A/pt not_active Application Discontinuation
- 2003-04-25 AU AU2003233066A patent/AU2003233066B2/en not_active Ceased
- 2003-04-25 MX MXPA05004330A patent/MXPA05004330A/es active IP Right Grant
- 2003-04-25 ME MEP-341/08A patent/MEP34108A/xx unknown
- 2003-04-25 RS YUP-2005/0321A patent/RS20050321A/sr unknown
- 2003-04-25 JP JP2005501510A patent/JP5204374B2/ja not_active Expired - Fee Related
- 2003-04-25 CN CN038254182A patent/CN1703205B/zh not_active Expired - Fee Related
- 2003-04-25 CA CA2503383A patent/CA2503383C/en not_active Expired - Fee Related
- 2003-04-25 ME MEP-2008-341A patent/ME00233B/me unknown
- 2003-04-25 ES ES03727364.6T patent/ES2618300T3/es not_active Expired - Lifetime
- 2003-04-25 PL PL376537A patent/PL376537A1/pl not_active Application Discontinuation
- 2003-04-28 AR ARP030101458A patent/AR039464A1/es not_active Application Discontinuation
-
2005
- 2005-04-19 ZA ZA200503133A patent/ZA200503133B/en unknown
- 2005-05-17 CO CO05047639A patent/CO5700711A2/es not_active Application Discontinuation
- 2005-05-20 MA MA28292A patent/MA27493A1/fr unknown
- 2005-05-23 NO NO20052480A patent/NO20052480L/no not_active Application Discontinuation
-
2009
- 2009-04-01 RU RU2009112072/15A patent/RU2009112072A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1703205A (zh) | 2005-11-30 |
| CN101327326A (zh) | 2008-12-24 |
| WO2004037229A1 (en) | 2004-05-06 |
| KR20050083802A (ko) | 2005-08-26 |
| CA2503383C (en) | 2013-03-12 |
| NZ539512A (en) | 2009-03-31 |
| CA2503383A1 (en) | 2004-05-06 |
| ZA200503133B (en) | 2006-12-27 |
| EP1556015A1 (en) | 2005-07-27 |
| PE20081613A1 (es) | 2008-11-15 |
| TW200406223A (en) | 2004-05-01 |
| NO20052480L (no) | 2005-07-25 |
| PE20040323A1 (es) | 2004-06-10 |
| MXPA05004330A (es) | 2005-08-02 |
| MA27493A1 (fr) | 2005-08-01 |
| PL376537A1 (pl) | 2006-01-09 |
| JP5204374B2 (ja) | 2013-06-05 |
| HRP20050448A2 (en) | 2005-12-31 |
| RU2005115574A (ru) | 2005-10-27 |
| AU2003233066B2 (en) | 2009-11-19 |
| NO20052480D0 (no) | 2005-05-23 |
| RU2009112072A (ru) | 2010-10-10 |
| BR0315576A (pt) | 2005-08-30 |
| RS20050321A (sr) | 2007-08-03 |
| JP2006506453A (ja) | 2006-02-23 |
| MEP34108A (hr) | 2011-02-10 |
| ME00233B (me) | 2011-05-10 |
| EP1556015B1 (en) | 2017-02-22 |
| ES2618300T3 (es) | 2017-06-21 |
| CN1703205B (zh) | 2010-12-01 |
| AU2003233066A1 (en) | 2004-05-13 |
| AR039464A1 (es) | 2005-02-23 |
| RU2366410C2 (ru) | 2009-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |