[go: up one dir, main page]

CO5540380A2 - Medicamentos inhalativos que contienen un nuevo anticolinergico en combinacion con corticosteroides y betamimeticos - Google Patents

Medicamentos inhalativos que contienen un nuevo anticolinergico en combinacion con corticosteroides y betamimeticos

Info

Publication number
CO5540380A2
CO5540380A2 CO05024193A CO05024193A CO5540380A2 CO 5540380 A2 CO5540380 A2 CO 5540380A2 CO 05024193 A CO05024193 A CO 05024193A CO 05024193 A CO05024193 A CO 05024193A CO 5540380 A2 CO5540380 A2 CO 5540380A2
Authority
CO
Colombia
Prior art keywords
combination
anticholinergic
beta
polinergic
betamimetics
Prior art date
Application number
CO05024193A
Other languages
English (en)
Inventor
Michel Pairet
Meade Christopher John Montangue
Michael Paul Pieper
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of CO5540380A2 publication Critical patent/CO5540380A2/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1.- Medicamento para la inhalación, caracterizado por un contenido en al menos un anticolinérgico de la fórmula 1, en donde X ¯ significa un anión cargado negativamente una vez, preferiblemente un anión elegido del grupo consistente en cloruro, bromuro, yoduro, sulfato, fosfato, metanosulfonato, nitrato, maleato, acetato, citrato, fumarato, tartrato, oxalato, succinato, benzoato y p-toluenosulfonato, al menos un corticosteroide (2), así como al menos un betamimético (3), eventualmente en forma de sus enantiómeros, mezclas de los enantiómeros o en forma de los racematos, eventualmente en forma de los solvatos o hidratos, así como, eventualmente, junto con un coadyuvante fisiológicamente inocuo.2.- Medicamento según la reivindicación 1, caracterizado porque los principios activos 1, 2 y 3 están contenidos en común en una única forma de administración o en dos o tres formas de administración separadas.3.- Medicamento según una de las reivindicaciones 1 ó 2, caracterizado porque 1 se elige del grupo de las sales, en las que X ¯ representa un anión cargado negativamente una vez, elegido del grupo consistente en cloruro, bromuro, 4-toluenosulfonato y metanosulfonato, preferiblemente bromuro.
CO05024193A 2002-08-17 2005-03-15 Medicamentos inhalativos que contienen un nuevo anticolinergico en combinacion con corticosteroides y betamimeticos CO5540380A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10237739A DE10237739A1 (de) 2002-08-17 2002-08-17 Inhalative Arzneimittel enthaltend ein neues Anticholinergikum in Kombination mit Corticosteroiden und Betamimetika

Publications (1)

Publication Number Publication Date
CO5540380A2 true CO5540380A2 (es) 2005-07-29

Family

ID=30775387

Family Applications (1)

Application Number Title Priority Date Filing Date
CO05024193A CO5540380A2 (es) 2002-08-17 2005-03-15 Medicamentos inhalativos que contienen un nuevo anticolinergico en combinacion con corticosteroides y betamimeticos

Country Status (21)

Country Link
EP (2) EP1530471B1 (es)
JP (1) JP2006501253A (es)
KR (1) KR101083977B1 (es)
CN (1) CN1688308A (es)
AT (1) ATE366574T1 (es)
AU (1) AU2003255289B2 (es)
BR (1) BR0313526A (es)
CA (1) CA2495454C (es)
CO (1) CO5540380A2 (es)
CY (1) CY1107742T1 (es)
DE (2) DE10237739A1 (es)
DK (1) DK1530471T3 (es)
ES (1) ES2290549T3 (es)
IL (1) IL166891A (es)
MX (1) MXPA05001823A (es)
NZ (1) NZ538834A (es)
PL (1) PL212070B1 (es)
PT (1) PT1530471E (es)
RU (1) RU2332217C2 (es)
WO (1) WO2004022058A1 (es)
ZA (1) ZA200500019B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ304043B6 (cs) 2000-08-05 2013-09-04 Glaxo Group Limited Estery steroidních thiokyselin
US7291608B2 (en) 2001-04-30 2007-11-06 Glaxo Group Limited Anti-inflammatory 17.β.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.α
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
DE102004024453A1 (de) * 2004-05-14 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Bronchodilatoren zur Behandlung von Atemwegserkrankungen
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
US7745621B2 (en) 2004-05-14 2010-06-29 Boehringer Ingelheim International Gmbh Long acting bronchodilators for the treatment of respiratory diseases
US20060034776A1 (en) * 2004-08-10 2006-02-16 Boehringer Ingelheim International Gmbh Inhalable medicaments containing a new anticholinergic, corticosteroids, and betamimetics
DE102004056578A1 (de) * 2004-11-23 2006-05-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalative Arzneimittel enthaltend ein neues Anticholinergikum, Formoterol und ein Steroid
DE102004056579A1 (de) * 2004-11-23 2006-05-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalative Arzneimittel enthaltend ein neues Anticholinergikum, Salmeterol und ein Steroid
UA92732C2 (ru) 2005-02-25 2010-12-10 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Фармацевтические аэрозольные композиции для ингаляторов под давлением с вымеренными дозами, которые содержат связующее соединение
MX2007012084A (es) * 2005-03-30 2007-11-21 Schering Corp Medicamentos y metodos que combinan un anticolinergico, un corticosteroide y un agonista beta de accion prolongada.
RU2369411C2 (ru) * 2005-04-21 2009-10-10 Бёрингер Ингельхайм Интернациональ Гмбх Порошковый ингалятор
CA2607391A1 (en) * 2005-04-23 2006-11-02 Boehringer Ingelheim International Gmbh Combination of medicaments to be inhaled, containing a betamimetic agent and a steroid in addition to an anticholinergic agent
RU2431501C2 (ru) * 2005-07-14 2011-10-20 Липотера, Инк. Липолитические составы с пролонгированным высвобождением для локального лечения отложения жировых тканей
WO2007020227A1 (de) 2005-08-15 2007-02-22 Boehringer Ingelheim International Gmbh Verfahren zur herstellung von betamimetika
MX2010004529A (es) * 2007-10-25 2010-05-10 Merck Frosst Canada Ltd Composiciones de inhalacion que comprenden acido montelukast y un inhibidor de fosfodiesterasa-4 o un corticoesteroide inhalado.
EP3106149B1 (en) 2009-05-29 2019-11-20 Pearl Therapeutics, Inc. Compositions for pulmonary delivery of long-acting muscarinic antagonists and long-acting beta-2 adrenergic receptor agonists and associated methods and systems
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
RU2479304C1 (ru) * 2012-05-29 2013-04-20 Шолекс Девелопмент Гмбх, Стабильный раствор фенотерола гидробромида
RU2504382C1 (ru) * 2012-06-13 2014-01-20 Шолекс Девелопмент Гмбх Ингаляционный препарат для лечения бронхиальной астмы и хронической обструктивной болезни легких и способ его получения
ES2706757T3 (es) 2012-12-21 2019-04-01 Boehringer Ingelheim Vetmedica Gmbh Formulación farmacéutica que comprende ciclesonida
SI2934479T1 (sl) 2012-12-21 2019-01-31 Boehringer Ingelheim Vetmedica Gmbh Ciklezonid za zdravljenje bolezni dihalnih poti pri konjih
BR112015022784B1 (pt) 2013-03-15 2023-02-14 Pearl Therapeutics, Inc Método de condicionamento de material cristalino micronizado e sistemas de condicionamento
WO2015065220A1 (ru) * 2013-10-28 2015-05-07 Шолекс Девелопмент Гмбх Ингаляционный препарат для лечения бронхиальной астмы и хронической обструктивной болезни легких и способ его получения
WO2015065223A1 (ru) * 2013-10-28 2015-05-07 Шолекс Девелопмент Гмбх Стабильный раствор фенотерола гидробромида
ES2759247T3 (es) * 2014-06-18 2020-05-08 Boehringer Ingelheim Vetmedica Gmbh Antagonistas muscarínicos y combinaciones de estos para el tratamiento de enfermedades de las vías respiratorias en caballos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0003935D0 (en) * 2000-02-08 2000-04-12 King S College London Formulation for dry powder inhaler
CN1213732C (zh) * 2000-05-22 2005-08-10 奇斯药制品公司 用于加压计量吸入器的稳定药用溶液制剂
DE10050994A1 (de) * 2000-10-14 2002-04-18 Boehringer Ingelheim Pharma Neue als Arneimittel einsetzbare Anticholinergika sowie Verfahren zu deren Herstellung
DE10130371A1 (de) * 2001-06-23 2003-01-02 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika

Also Published As

Publication number Publication date
IL166891A (en) 2010-04-15
ATE366574T1 (de) 2007-08-15
AU2003255289A1 (en) 2004-03-29
EP1785136A3 (de) 2009-04-22
DE10237739A1 (de) 2004-02-26
KR101083977B1 (ko) 2011-11-22
CA2495454C (en) 2011-09-06
CN1688308A (zh) 2005-10-26
ES2290549T3 (es) 2008-02-16
MXPA05001823A (es) 2005-04-19
AU2003255289B2 (en) 2009-08-20
CY1107742T1 (el) 2013-04-18
BR0313526A (pt) 2005-06-28
EP1785136A2 (de) 2007-05-16
ZA200500019B (en) 2006-07-26
EP1530471B1 (de) 2007-07-11
PL375233A1 (en) 2005-11-28
EP1530471A1 (de) 2005-05-18
NZ538834A (en) 2007-10-26
CA2495454A1 (en) 2004-03-18
RU2332217C2 (ru) 2008-08-27
KR20050051644A (ko) 2005-06-01
PL212070B1 (pl) 2012-08-31
PT1530471E (pt) 2007-07-26
RU2005107475A (ru) 2006-04-10
JP2006501253A (ja) 2006-01-12
WO2004022058A1 (de) 2004-03-18
DE50307659D1 (de) 2007-08-23
DK1530471T3 (da) 2007-10-22

Similar Documents

Publication Publication Date Title
CO5540380A2 (es) Medicamentos inhalativos que contienen un nuevo anticolinergico en combinacion con corticosteroides y betamimeticos
UY27938A1 (es) Formulacion aerosol para inhalacion, que contiene un agente anticolinergico
NO20061833L (no) Aerosolformulgering for inhalering, inneholdende anticholinergt middel
RU2005121162A (ru) Производные хинуклидина, фармацевтическая композиция и способ лечения респираторных, урологических или желудочно-кишечных заболеваний
AR035589A1 (es) Esteres de acido difenilmetilcarboxilico con efecto anticolinergico, un procedimiento para su preparacion, el uso de los mismos para la preparacion de un medicamento y los preparados farmaceuticos que los contienen
HRP20031066B1 (en) Crystalline anticholinergic, method for its production, and use thereof in the production of a drug
AR062424A1 (es) Formulacion en aerosol para la inhalacion de beta - agonistas
AR039404A1 (es) Combinaciones de medicamentos que contienen compuestos heterociclicos y un agente anticolinergico. aerosol para su inhalacion
ZA200409676B (en) Novel drug compositions based on novel anticholinergics and inhibitors of EGFR-kinase
AR039275A1 (es) Medicamento que contiene esteroides y un nuevo anticolinergico
MY132777A (en) Inhalable formulation of a solution containing a tiotropium salt
AR059126A1 (es) Uso de sales de tiotropio en el tratamiento del asma persistente moderada
AR055597A1 (es) Uso de sales de tiotripio en el tratamiento del asma persistente severa
AU2003222290A1 (en) Novel ester hydroxy-substituted nitrogen heterocycles as antagonists of the muscarinic m3 receptor, methods for the production thereof, and use thereof as a medicament
CN107863039A (zh) 一种医院设备管理创新用展示宣传装置
ATE341547T1 (de) Difurylglykolsäuretropenolester als anticholinergika
TH65935A (th) ยาซึ่งประกอบรวมด้วยสเตอรอยด์ และแอนตีโคลิเนอร์จิคตัวใหม่
CO5700760A2 (es) Nuevas composiciones de medicamentos a base de nuevos anti- colinergicos e inhibidores de egfr-quinasa

Legal Events

Date Code Title Description
FC Application refused