CO5540379A2 - Capsulas para inhalacion - Google Patents
Capsulas para inhalacionInfo
- Publication number
- CO5540379A2 CO5540379A2 CO03108303A CO03108303A CO5540379A2 CO 5540379 A2 CO5540379 A2 CO 5540379A2 CO 03108303 A CO03108303 A CO 03108303A CO 03108303 A CO03108303 A CO 03108303A CO 5540379 A2 CO5540379 A2 CO 5540379A2
- Authority
- CO
- Colombia
- Prior art keywords
- capsules
- inhalation
- cellulose
- gelatin
- peg
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/003—Particle size control by passing the aerosol trough sieves or filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1.- Cápsulas para inhalación, que como polvo inhalable contienen tiotropio en mezcla con una sustancia auxiliar fisiológicamente inocua, caracterizadas porque el material de las cápsulas presenta un contenido reducido de humedad (humedad TEWS de secador con halógeno de menos que 15 % ).2.- Cápsulas para inhalación según la reivindicación 1, caracterizadas porque el material de las cápsulas se selecciona entre el grupo que consta de gelatina, derivados de celulosa, almidón, derivados de almidón, quitosana y materiales plásticos sintéticos.3.- Cápsulas para inhalación según la reivindicación 2, caracterizadas porque como material de las cápsulas se utiliza una gelatina en mezcla con otros aditivos seleccionados entre el grupo que consta de polietilen-glicol (PEG), con preferencia PEG 3350, glicerol, sorbitol, propilen-glicol, copolímeros de bloques PEO-PPO, y otros polialcoholes y poliéteres.4.- Cápsulas para inhalación según la reivindicación 3, caracterizadas porque el material de las cápsulas contiene, además de gelatina, un PEG en una proporción de 1 - 10 % (% en peso), con preferencia de 3 - 8 %.5.- Cápsulas para inhalación según la reivindicación 3 ó 4, caracterizadas porque el material de las cápsulas presenta una humedad TEWS o de secador con halógeno de menos que 12 %, de modo especialmente preferido de = 10 %.6.- Cápsulas para inhalación según la reivindicación 2, caracterizadas porque el material de las cápsulas se selecciona entre el grupo de los derivados de celulosa hidroxipropil-metil-celulosa, hidroxipropil-celulosa, metil-celulosa, hidroximetil-celulosa e hidroxietil-celulosa.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10126924A DE10126924A1 (de) | 2001-06-01 | 2001-06-01 | Inhalationskapseln |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5540379A2 true CO5540379A2 (es) | 2005-07-29 |
Family
ID=7687020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO03108303A CO5540379A2 (es) | 2001-06-01 | 2003-12-10 | Capsulas para inhalacion |
Country Status (37)
| Country | Link |
|---|---|
| EP (2) | EP1508330A1 (es) |
| JP (3) | JP4447311B2 (es) |
| KR (2) | KR100921904B1 (es) |
| CN (3) | CN101697965A (es) |
| AR (2) | AR034346A1 (es) |
| AT (1) | ATE285752T1 (es) |
| AU (2) | AU2002344354B2 (es) |
| BG (1) | BG65655B1 (es) |
| BR (1) | BR0209366A (es) |
| CA (1) | CA2448425C (es) |
| CH (1) | CH1379220H1 (es) |
| CO (1) | CO5540379A2 (es) |
| CZ (1) | CZ300284B6 (es) |
| DE (2) | DE10126924A1 (es) |
| EA (1) | EA005188B1 (es) |
| EC (2) | ECSP034868A (es) |
| EE (1) | EE05416B1 (es) |
| EG (1) | EG24227A (es) |
| ES (1) | ES2236590B5 (es) |
| HR (1) | HRP20030993B1 (es) |
| HU (3) | HU230827B1 (es) |
| IL (2) | IL158917A0 (es) |
| ME (1) | ME00301B (es) |
| MX (1) | MXPA03010990A (es) |
| MY (1) | MY126253A (es) |
| NO (1) | NO332857B3 (es) |
| NZ (1) | NZ530356A (es) |
| PE (1) | PE20030071A1 (es) |
| PL (2) | PL203801B1 (es) |
| PT (1) | PT1379220E (es) |
| RS (1) | RS50353B (es) |
| SI (1) | SI1379220T1 (es) |
| SK (2) | SK287346B6 (es) |
| TW (1) | TWI327921B (es) |
| UA (1) | UA75659C2 (es) |
| WO (1) | WO2002098874A2 (es) |
| ZA (1) | ZA200308340B (es) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2395653C (en) | 2000-10-12 | 2006-05-09 | Boehringer Ingelheim Pharma Kg | New inhalable powder containing tiotropium |
| DE10126924A1 (de) * | 2001-06-01 | 2002-12-05 | Boehringer Ingelheim Pharma | Inhalationskapseln |
| DE10212264A1 (de) | 2002-03-20 | 2003-10-02 | Boehringer Ingelheim Pharma | Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels |
| US20040025876A1 (en) * | 2002-05-07 | 2004-02-12 | Danforth Miller | Capsules for dry powder inhalers and methods of making and using same |
| DE10255387A1 (de) * | 2002-11-28 | 2004-06-09 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Tiotropium-haltige Pulverformulierung für die Inhalation |
| US7763280B2 (en) | 2002-11-28 | 2010-07-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing powder formulation for inhalation |
| DE10258360A1 (de) * | 2002-12-12 | 2004-06-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator mit Kapselkammer zum Aufnehmen einer mit Wirkstoff gefüllten Einwegkapsel |
| DE10352277A1 (de) * | 2003-11-08 | 2005-06-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| SE0303269L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Medicinsk produkt |
| SE0303570L (sv) | 2003-12-03 | 2005-06-04 | Microdrug Ag | Fukt-känslig medicinsk produkt |
| GB0503738D0 (en) | 2005-02-23 | 2005-03-30 | Optinose As | Powder delivery devices |
| RU2369411C2 (ru) * | 2005-04-21 | 2009-10-10 | Бёрингер Ингельхайм Интернациональ Гмбх | Порошковый ингалятор |
| US7694676B2 (en) | 2005-04-22 | 2010-04-13 | Boehringer Ingelheim Gmbh | Dry powder inhaler |
| JP4825455B2 (ja) * | 2005-05-02 | 2011-11-30 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 粉末吸入器 |
| DE102006016901A1 (de) | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Mundstück für einen Inhalator |
| DE102006016904A1 (de) | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator |
| GB0716026D0 (en) * | 2007-08-16 | 2007-09-26 | Norton Healthcare Ltd | An inhalable medicament |
| DE102007036411A1 (de) | 2007-07-20 | 2009-02-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| DE102007052871A1 (de) * | 2007-11-02 | 2009-05-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Kapsel zur Aufnahme von pharmazeutischen Wirkstoffformulierungen |
| CA2714178A1 (en) * | 2008-02-08 | 2009-08-13 | Boehringer Ingelheim International Gmbh | Method and device for filling capsules |
| EP2172190A1 (en) * | 2008-10-02 | 2010-04-07 | Laboratorios Liconsa, S.A. | Inhalable particles comprising tiotropium |
| ES2739352T3 (es) | 2009-02-26 | 2020-01-30 | Glaxo Group Ltd | Formulaciones farmacéuticas que comprenden 4-{(1R)-2-[(6-{2-[(2,6-diclorobencil)oxi]etoxi}hexil)amino]-1-hidroxietil}-2-(hidroximetil)fenol |
| EP2411008B1 (en) * | 2009-03-27 | 2017-03-22 | Mahmut Bilgic | Complexes of tiotropium with improved properties of solubility and stability |
| GB0921075D0 (en) | 2009-12-01 | 2010-01-13 | Glaxo Group Ltd | Novel combination of the therapeutic agents |
| EP2575786B1 (en) | 2010-06-03 | 2017-11-15 | Sima Patent ve Lisanslama Hizmetleri Ltd.Sti. | Process for dry powder formulations |
| DE202011102694U1 (de) | 2011-06-29 | 2011-12-19 | Zisser Gmbh | Inhalationsgerät für Heimanwender |
| GB201200525D0 (en) | 2011-12-19 | 2012-02-29 | Teva Branded Pharmaceutical Prod R & D Inc | An inhalable medicament |
| US20150150802A1 (en) | 2012-07-05 | 2015-06-04 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Dry powder inhaler compositions comprising long acting muscarinic antagonists |
| DE202013000774U1 (de) | 2013-01-21 | 2013-04-15 | Rhinofilt GmbH | Miniaturisiertes Inhalationsgerät zur Privatanwendung |
| US10034866B2 (en) | 2014-06-19 | 2018-07-31 | Teva Branded Pharmaceutical Products R&D, Inc. | Inhalable medicament comprising tiotropium |
| CN108295042A (zh) * | 2018-03-05 | 2018-07-20 | 上海祺宇生物科技有限公司 | 一种用于吸入药剂的植物空心胶囊及其胶囊剂 |
| CN108451920A (zh) * | 2018-03-14 | 2018-08-28 | 绍兴康可胶囊有限公司 | 一种吸雾式胶囊及其制备方法 |
| CN114848605B (zh) * | 2022-03-25 | 2023-08-11 | 上海方予健康医药科技有限公司 | 一种供吸入粉雾剂用的明胶胶囊 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3931041C2 (de) * | 1989-09-16 | 2000-04-06 | Boehringer Ingelheim Kg | Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| WO1993025193A1 (fr) * | 1992-06-12 | 1993-12-23 | Teijin Limited | Preparation pharmaceutique destinee a etre administree par les voies respiratoires |
| US6228394B1 (en) * | 1997-10-14 | 2001-05-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Supercritical fluid extraction of mould lubricant from hard shell capsules |
| DE19835346A1 (de) * | 1998-08-05 | 2000-02-10 | Boehringer Ingelheim Pharma | Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren |
| JP2000143502A (ja) * | 1998-11-11 | 2000-05-23 | Shionogi Qualicaps Kk | 吸入製剤 |
| DK1131059T3 (da) * | 1998-11-13 | 2003-06-30 | Jago Res Ag | Tørpulver til inhalation |
| DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
| EP1072258A1 (de) * | 1999-07-28 | 2001-01-31 | Greither, Peter | Eine Kapsel für die Freisetzung von Bakterien, enthaltend ein Bakterienlyophilisat und ein Verfahren zu ihrer Herstellung |
| CA2387212A1 (en) * | 1999-10-12 | 2001-04-19 | Kaken Pharmaceutical Co., Ltd. | Dry powder inhalation and a method for the preparation thereof |
| DE10126924A1 (de) * | 2001-06-01 | 2002-12-05 | Boehringer Ingelheim Pharma | Inhalationskapseln |
-
2001
- 2001-06-01 DE DE10126924A patent/DE10126924A1/de not_active Withdrawn
-
2002
- 2002-05-27 EA EA200301275A patent/EA005188B1/ru not_active IP Right Cessation
- 2002-05-27 BR BR0209366-9A patent/BR0209366A/pt not_active Application Discontinuation
- 2002-05-27 ES ES02776507.2T patent/ES2236590B5/es not_active Expired - Lifetime
- 2002-05-27 ME MEP-2008-425A patent/ME00301B/me unknown
- 2002-05-27 CZ CZ20033579A patent/CZ300284B6/cs not_active IP Right Cessation
- 2002-05-27 EE EEP200300595A patent/EE05416B1/xx unknown
- 2002-05-27 HR HR20030993A patent/HRP20030993B1/xx not_active IP Right Cessation
- 2002-05-27 CA CA2448425A patent/CA2448425C/en not_active Expired - Fee Related
- 2002-05-27 DE DE50201898T patent/DE50201898D1/de not_active Expired - Lifetime
- 2002-05-27 SI SI200230077T patent/SI1379220T1/xx unknown
- 2002-05-27 EP EP04026411A patent/EP1508330A1/de not_active Withdrawn
- 2002-05-27 AT AT02776507T patent/ATE285752T1/de active
- 2002-05-27 JP JP2003501995A patent/JP4447311B2/ja not_active Expired - Lifetime
- 2002-05-27 SK SK50049-2009A patent/SK287346B6/sk not_active IP Right Cessation
- 2002-05-27 EP EP02776507A patent/EP1379220B1/de not_active Expired - Lifetime
- 2002-05-27 CN CN200910149591A patent/CN101697965A/zh active Pending
- 2002-05-27 HU HU1500188A patent/HU230827B1/hu unknown
- 2002-05-27 PL PL364108A patent/PL203801B1/pl unknown
- 2002-05-27 NZ NZ530356A patent/NZ530356A/en not_active IP Right Cessation
- 2002-05-27 KR KR1020037015718A patent/KR100921904B1/ko not_active Expired - Lifetime
- 2002-05-27 IL IL15891702A patent/IL158917A0/xx unknown
- 2002-05-27 SK SK1620-2003A patent/SK287379B6/sk not_active IP Right Cessation
- 2002-05-27 CN CN201010143914A patent/CN101829072A/zh active Pending
- 2002-05-27 KR KR1020097000835A patent/KR100952321B1/ko not_active Expired - Lifetime
- 2002-05-27 PT PT02776507T patent/PT1379220E/pt unknown
- 2002-05-27 CH CH02776507T patent/CH1379220H1/de unknown
- 2002-05-27 PL PL387118A patent/PL205714B1/pl unknown
- 2002-05-27 HU HU1800092A patent/HU231082B1/hu unknown
- 2002-05-27 UA UA20031212504A patent/UA75659C2/uk unknown
- 2002-05-27 RS YUP-935/03A patent/RS50353B/sr unknown
- 2002-05-27 MX MXPA03010990A patent/MXPA03010990A/es active IP Right Grant
- 2002-05-27 AU AU2002344354A patent/AU2002344354B2/en not_active Expired
- 2002-05-27 WO PCT/EP2002/005600 patent/WO2002098874A2/de not_active Ceased
- 2002-05-27 HU HU0400666A patent/HU230058B1/hu not_active IP Right Cessation
- 2002-05-27 CN CNA028109791A patent/CN1512875A/zh active Pending
- 2002-05-29 AR ARP020102000A patent/AR034346A1/es not_active Application Discontinuation
- 2002-05-29 EG EG20020570A patent/EG24227A/xx active
- 2002-05-31 TW TW091111706A patent/TWI327921B/zh not_active IP Right Cessation
- 2002-05-31 MY MYPI20022036A patent/MY126253A/en unknown
- 2002-05-31 PE PE2002000465A patent/PE20030071A1/es active IP Right Grant
-
2003
- 2003-10-27 ZA ZA200308340A patent/ZA200308340B/xx unknown
- 2003-11-18 IL IL158917A patent/IL158917A/en active IP Right Grant
- 2003-11-24 BG BG108380A patent/BG65655B1/bg unknown
- 2003-11-27 EC EC2003004868A patent/ECSP034868A/es unknown
- 2003-11-27 NO NO20035265A patent/NO332857B3/no not_active IP Right Cessation
- 2003-12-10 CO CO03108303A patent/CO5540379A2/es not_active Application Discontinuation
-
2006
- 2006-02-15 JP JP2006038063A patent/JP4787034B2/ja not_active Expired - Lifetime
-
2007
- 2007-10-03 JP JP2007260177A patent/JP2008050364A/ja active Pending
-
2008
- 2008-07-10 AU AU2008203057A patent/AU2008203057C1/en not_active Expired
-
2011
- 2011-01-06 EC EC2011004868A patent/ECSP11004868A/es unknown
-
2012
- 2012-01-06 AR ARP120100053A patent/AR084804A2/es not_active Application Discontinuation
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