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CO5190660A1 - Formulacion farmaceutica comprenden dos o mas unidades conectadas - Google Patents

Formulacion farmaceutica comprenden dos o mas unidades conectadas

Info

Publication number
CO5190660A1
CO5190660A1 CO00056905A CO00056905A CO5190660A1 CO 5190660 A1 CO5190660 A1 CO 5190660A1 CO 00056905 A CO00056905 A CO 00056905A CO 00056905 A CO00056905 A CO 00056905A CO 5190660 A1 CO5190660 A1 CO 5190660A1
Authority
CO
Colombia
Prior art keywords
drug substance
capsule
compartment
capsule compartment
weld
Prior art date
Application number
CO00056905A
Other languages
English (en)
Inventor
Allan J Clarke
Fonio Teodoro
Geoffrey Arthur Harris
Ronald Kift
Danald Lightfoot
Mcginley Shane
Thomas Ofsharick
Margaret Mary Szymczak
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9917775.0A external-priority patent/GB9917775D0/en
Priority claimed from GBGB9917772.7A external-priority patent/GB9917772D0/en
Priority claimed from GBGB9917774.3A external-priority patent/GB9917774D0/en
Priority claimed from GBGB9917777.6A external-priority patent/GB9917777D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of CO5190660A1 publication Critical patent/CO5190660A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Una forma de dosis farmacéutica de múltiples componentes, que comprende una pluralidad de subunidades de contención de sustancia medicamentosa, cada una seleccionada de compartimentos de cápsula que pueden desprender su sustancia medicamentosa en el ambiente gastrointestinal, y subunidades sólidas que comprenden una matriz sólida de un polímero que contiene una sustancia medicamentosa, siendo el polímero soluble, dispersable o desintegrable en el ambiente gastrointestinal del paciente para desprender de este modo la sustancia medicamentosa, estando conectadas las subunidades entre sí en la forma farmacéutica montada y siendo retenidas juntas mediante la conexión al menos antes de la administración a un paciente, en que la conexión es proporcionada por una soldadura entre partes de la forma farmacéutica montada.3Un procedimiento para fabricar una forma farmacéutica según una cualquiera de las reivindicaciones precedentes que comprende un compartimento de cápsula - unidad de enlace - compartimento de cápsula en una disposición lineal, caracterizado por las etapas de primero llenar un primer compartimento de cápsula con una cantidad adecuada de una sustancia medicamentosa; insertar una primera parte macho de una unidad de enlace en el extremo abierto del primer compartimento de cápsula y soldar éste en su sitio; llenar un segundo compartimento de cápsula que contiene una cantidad adecuada de sustancia medicamentosa; insertar la segunda parte macho opuesta de la unidad de enlace en el extremo abierto del segundo compartimento de cápsula y soldar la unidad de enlace y el segundo compartimento de cápsula entre sí.<EMI FILE="00056905_1" ID="1" IMF=JPEG >
CO00056905A 1999-07-30 2000-07-28 Formulacion farmaceutica comprenden dos o mas unidades conectadas CO5190660A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9917775.0A GB9917775D0 (en) 1999-07-30 1999-07-30 Pharmaceutical formulation
GBGB9917772.7A GB9917772D0 (en) 1999-07-30 1999-07-30 Pharmaceutical formulation
GBGB9917774.3A GB9917774D0 (en) 1999-07-30 1999-07-30 Pharmaceutical formulation
GBGB9917777.6A GB9917777D0 (en) 1999-07-30 1999-07-30 Pharmaceutical formulation

Publications (1)

Publication Number Publication Date
CO5190660A1 true CO5190660A1 (es) 2002-08-29

Family

ID=27451916

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00056905A CO5190660A1 (es) 1999-07-30 2000-07-28 Formulacion farmaceutica comprenden dos o mas unidades conectadas

Country Status (23)

Country Link
US (3) US7163693B1 (es)
EP (1) EP1204410B1 (es)
JP (1) JP4902918B2 (es)
KR (1) KR100710118B1 (es)
CN (1) CN1213740C (es)
AR (1) AR024966A1 (es)
AU (1) AU773800B2 (es)
BR (1) BR0012869A (es)
CA (1) CA2391707C (es)
CO (1) CO5190660A1 (es)
CZ (1) CZ2002336A3 (es)
DK (1) DK1204410T3 (es)
ES (1) ES2392393T3 (es)
HK (1) HK1047537A1 (es)
HU (1) HUP0201936A3 (es)
IL (2) IL147826A0 (es)
MX (1) MXPA02001080A (es)
MY (1) MY125298A (es)
NO (2) NO332155B1 (es)
NZ (1) NZ516733A (es)
PL (1) PL208550B1 (es)
TW (1) TWI236915B (es)
WO (1) WO2001008666A1 (es)

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NO20020464L (no) 2002-03-20
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EP1204410A1 (en) 2002-05-15
US7691407B2 (en) 2010-04-06
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US7163693B1 (en) 2007-01-16
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