CO2018013654A2 - Composiciones nasales de cannabidiol - Google Patents
Composiciones nasales de cannabidiolInfo
- Publication number
- CO2018013654A2 CO2018013654A2 CONC2018/0013654A CO2018013654A CO2018013654A2 CO 2018013654 A2 CO2018013654 A2 CO 2018013654A2 CO 2018013654 A CO2018013654 A CO 2018013654A CO 2018013654 A2 CO2018013654 A2 CO 2018013654A2
- Authority
- CO
- Colombia
- Prior art keywords
- nasal
- cannabidiol
- methods
- pharmaceutical compositions
- nasal compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/348—Cannabaceae
- A61K36/3482—Cannabis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/577—Malvaceae (Mallow family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Una composición de cannabinoides semisólida o líquida viscosa administrada por vía nasal, métodos nasales para la administración de las composiciones farmacéuticas nasales, métodos para la fabricación de composiciones farmacéuticas nasales, y métodos nasales para el tratamiento de enfermedades tratables por medio de composiciones farmacéuticas nasales formuladas con un cannabinoide o mezclas de estas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662344486P | 2016-06-02 | 2016-06-02 | |
| US201662426403P | 2016-11-25 | 2016-11-25 | |
| PCT/IB2017/000759 WO2017208072A2 (en) | 2016-06-02 | 2017-06-02 | Nasal cannabidiol compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2018013654A2 true CO2018013654A2 (es) | 2019-08-30 |
Family
ID=60478110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2018/0013654A CO2018013654A2 (es) | 2016-06-02 | 2018-12-17 | Composiciones nasales de cannabidiol |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20170348276A1 (es) |
| EP (1) | EP3478270A4 (es) |
| KR (1) | KR102433459B1 (es) |
| CN (1) | CN109789090A (es) |
| BR (1) | BR112018075073A2 (es) |
| CA (1) | CA3026274A1 (es) |
| CL (1) | CL2018003452A1 (es) |
| CO (1) | CO2018013654A2 (es) |
| MX (1) | MX392668B (es) |
| TW (1) | TWI790204B (es) |
| UY (1) | UY37271A (es) |
| WO (1) | WO2017208072A2 (es) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9907823B1 (en) | 2014-11-07 | 2018-03-06 | Eric H. Kuhrts | Water-soluble phytocannabinoid formulations |
| SI3687513T1 (sl) | 2017-09-28 | 2022-04-29 | Zynerba Pharmaceuticals, Inc. | Zdravljenje sindroma fragilnega kromosoma X in avtizma s kanabidiolom |
| US20190240148A1 (en) * | 2018-02-07 | 2019-08-08 | Tarukino Holdings, Inc. | Lubricant composition and method for preparing the composition |
| CA3092914A1 (en) * | 2018-03-05 | 2019-09-12 | Solva, Llc | Water-soluble phytocannabinoid formulations |
| US11020357B2 (en) * | 2018-03-19 | 2021-06-01 | Alexandra Yerike | Compound for use in relief of pain and method to produce thereof |
| EP3856172A4 (en) * | 2018-09-28 | 2022-10-05 | Visceral Therapeutics Inc. | Pharmaceutically active cannabis-based compositions and methods of use for treating gastrointestinal conditions |
| US20200170962A1 (en) * | 2018-11-30 | 2020-06-04 | F. Markus Leweke | Nasal cannabidiol compositions |
| CN113365635A (zh) * | 2018-12-14 | 2021-09-07 | 阿克罗斯生物制药公司 | 睾酮的活性酯衍生物、组合物和其用途 |
| KR20210104084A (ko) | 2018-12-14 | 2021-08-24 | 지네르바 파마슈티컬스, 인코포레이티드 | 칸나비디올을 사용하는 22q11.2 결실 증후군의 치료 |
| BR102018076973A2 (pt) * | 2018-12-21 | 2020-09-15 | Entourage Participações S.A. | Composição farmacêutica compreendendo extrato de cannabis, produto farmacêutico, processo de preparação da dita composição |
| WO2020142692A1 (en) * | 2019-01-04 | 2020-07-09 | Columbia Care Llc | Topical formulations having cannabinoid |
| US20200215024A1 (en) * | 2019-01-08 | 2020-07-09 | Replennabis LLC | Cannabinoid formulations for treating alcohol hangover |
| BR112021014976A2 (pt) * | 2019-02-08 | 2021-10-05 | Schedule 1 Therapeutics, Inc. | Composições compreendendo canabinoides e métodos de uso das mesmas |
| US10993928B2 (en) * | 2019-04-26 | 2021-05-04 | Natural Extraction Systems, LLC | Compositions comprising non-crystalline forms of cannabidiol |
| US20220257560A1 (en) * | 2019-05-23 | 2022-08-18 | India Globalization Capital, Inc. | Compositions and methods using cannabinoids for treating stammering/stuttering and symptoms of tourette syndrome |
| CN110433133A (zh) * | 2019-08-19 | 2019-11-12 | 中国人民解放军军事科学院军事医学研究院 | 治疗创伤后应激障碍的大麻二酚鼻用制剂 |
| ES2986160T3 (es) | 2019-08-30 | 2024-11-08 | Evie Sa | Gránulos cargados, su proceso de producción y sus usos |
| GB2588455B (en) * | 2019-10-25 | 2022-12-21 | Gw Res Ltd | Cannabinoid compound |
| US11419800B2 (en) | 2019-12-06 | 2022-08-23 | JLABS Beauty LLC | Topical compositions containing rose oil and cannabidiol and methods of making and using the same |
| TWI708835B (zh) * | 2020-01-17 | 2020-11-01 | 和協工程股份有限公司 | 緩釋型釋碳凝膠基質及土壤整治方法 |
| CH717205A1 (de) * | 2020-03-11 | 2021-09-15 | Jk Holding Gmbh | Verwendung von Cannabinoiden in Therapie- und Wellnessgeräten. |
| US20210322343A1 (en) * | 2020-04-15 | 2021-10-21 | Farzana Shaheen | Nasally administered pharmaceutical composition for the treatment of epilepsy and related disorders |
| EP4164613A4 (en) * | 2020-06-20 | 2024-10-23 | Chavan, Neha | COMPOSITIONS FOR SOLUBILISING WATER-INSOLUBLE ACTIVE SUBSTANCES |
| EP3984522A1 (de) * | 2020-10-19 | 2022-04-20 | Shima Khaki | Zusammensetzung, vorrichtung und verwendung |
| US12029720B2 (en) | 2021-04-29 | 2024-07-09 | Tilray Brands, Inc. | Cannabidiol-dominant formulations, methods of manufacturing, and uses thereof |
| IT202100014909A1 (it) * | 2021-06-08 | 2022-12-08 | Velleja Res S R L | Formulazioni oleose di cannabinoidi |
| CN113304109A (zh) * | 2021-06-08 | 2021-08-27 | 内蒙古大唐药业股份有限公司 | 一种醋柳黄酮固体脂质纳米粒分散液及其制备方法 |
| WO2023028708A1 (en) * | 2021-09-02 | 2023-03-09 | Canopy Growth Corporation | Water-soluble cannabinoid compositions, methods of making and use |
| US11471905B1 (en) | 2021-09-23 | 2022-10-18 | Apackaging Group Llc | All plastic airless pump dispenser |
| EP4186490A1 (en) | 2021-11-29 | 2023-05-31 | Sanity Group GmbH | Kit for preparing a medicament, cannabinoid composition, and preparation method |
| GB2634400A (en) * | 2022-03-15 | 2025-04-09 | Milehigh Repro Solutions Llc | Methods and systems to reduce injury in treated tissues |
| KR20250008060A (ko) | 2022-04-12 | 2025-01-14 | 섀클포드 파마 인코포레이티드 | 발작 장애의 치료 |
| WO2024010628A1 (en) * | 2022-07-05 | 2024-01-11 | Poviva Corp | Pharmaceutical compositions and methods for treating hypertension |
| US11666543B1 (en) * | 2022-07-05 | 2023-06-06 | Poviva Corp. | Pharmaceutical compositions and methods for treating hypertension |
| US11980593B2 (en) | 2022-07-05 | 2024-05-14 | Poviva Corp. | Compositions and methods for treating hypertension |
| WO2025024007A1 (en) * | 2023-07-24 | 2025-01-30 | Poviva Corp . | Compositions and methods for treating epilepsy |
| WO2025140869A1 (en) * | 2023-12-28 | 2025-07-03 | Linnea Sa | Process for stabilising a macerated oil |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9726916D0 (en) * | 1997-12-19 | 1998-02-18 | Danbiosyst Uk | Nasal formulation |
| DK1361864T3 (en) * | 2001-02-14 | 2014-03-03 | Gw Pharma Ltd | FLYLDENDE SPRAY FORMULATIONS FOR buccal administration of cannabinoids |
| GB0103638D0 (en) * | 2001-02-14 | 2001-03-28 | Gw Pharmaceuticals Ltd | Pharmaceutical formulations |
| GB2392093B (en) * | 2002-08-14 | 2006-03-08 | Gw Pharma Ltd | Pharmaceutical formulations |
| CN101132781A (zh) * | 2004-12-09 | 2008-02-27 | 茵西斯医疗公司 | 在室温下稳定的屈大麻酚剂型 |
| US20070060639A1 (en) * | 2005-09-09 | 2007-03-15 | University Of Kentucky | Compositions and methods for intranasal delivery of tricyclic cannabinoids |
| KR20240162608A (ko) * | 2011-05-15 | 2024-11-15 | 에이세러스 바이오파마 인크. | 비내용 테스토스테론 바이오-접착제 겔 제형 및 남성의 성선기능저하증을 치료하기 위한 그의 용도 |
-
2017
- 2017-06-02 CA CA3026274A patent/CA3026274A1/en active Pending
- 2017-06-02 UY UY0001037271A patent/UY37271A/es not_active Application Discontinuation
- 2017-06-02 BR BR112018075073-5A patent/BR112018075073A2/pt not_active Application Discontinuation
- 2017-06-02 MX MX2018014978A patent/MX392668B/es unknown
- 2017-06-02 US US15/613,116 patent/US20170348276A1/en not_active Abandoned
- 2017-06-02 TW TW106118333A patent/TWI790204B/zh not_active IP Right Cessation
- 2017-06-02 WO PCT/IB2017/000759 patent/WO2017208072A2/en not_active Ceased
- 2017-06-02 CN CN201780041815.6A patent/CN109789090A/zh active Pending
- 2017-06-02 EP EP17805945.7A patent/EP3478270A4/en not_active Withdrawn
- 2017-06-02 KR KR1020187038219A patent/KR102433459B1/ko active Active
-
2018
- 2018-12-03 CL CL2018003452A patent/CL2018003452A1/es unknown
- 2018-12-17 CO CONC2018/0013654A patent/CO2018013654A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017208072A2 (en) | 2017-12-07 |
| EP3478270A4 (en) | 2019-11-27 |
| CN109789090A (zh) | 2019-05-21 |
| TWI790204B (zh) | 2023-01-21 |
| TW201801721A (zh) | 2018-01-16 |
| WO2017208072A3 (en) | 2018-01-11 |
| MX2018014978A (es) | 2019-09-04 |
| EP3478270A2 (en) | 2019-05-08 |
| CA3026274A1 (en) | 2017-12-07 |
| MX392668B (es) | 2025-03-24 |
| KR20190034506A (ko) | 2019-04-02 |
| BR112018075073A2 (pt) | 2019-04-30 |
| KR102433459B1 (ko) | 2022-08-17 |
| US20170348276A1 (en) | 2017-12-07 |
| UY37271A (es) | 2017-11-30 |
| CL2018003452A1 (es) | 2019-06-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO2018013654A2 (es) | Composiciones nasales de cannabidiol | |
| MX2020004467A (es) | Metodos para el tratamiento o la prevencion del asma mediante la administracion de antagonista de il-4r. | |
| BR112018076601A2 (pt) | formulação farmacêutica oral, métodos para tratar um paciente, e, uso de uma formulação | |
| MX385332B (es) | Moduladores de ror-gamma. | |
| MX387442B (es) | Composiciones y tratamientos para el trastorno del sueño | |
| MX2019000588A (es) | Moduladores de la somatostatina y usos de los mismos. | |
| CL2018002758A1 (es) | Derivados de indolina sustituidos como inhibidores de la replicación viral del dengue. | |
| MX2019011606A (es) | Derivados de indolina sustituidos como inhibidores de la replicacion virica de dengue. | |
| CL2018002718A1 (es) | Derivados de indolina sustituidos como inhibidores de la replicación vírica de dengue. | |
| MX2019013878A (es) | Derivados de indolina sustituidos como inhibidores de la replicacion virica de dengue. | |
| CL2019001658A1 (es) | Derivados de la pirimidin enona tricíclica para la inhibición de rory y otros usos. | |
| EA201991447A1 (ru) | Снижение вязкости фармацевтических составов | |
| MX2018015985A (es) | Composiciones, dispositivos y metodos para el tratamiento del trastorno relacionado con el consumo de alcohol. | |
| MX2019013893A (es) | Derivados de indolina sustituidos como inhibidores de la replicacion virica de dengue. | |
| MX2019001633A (es) | Proteina derivada de la seda para el tratamiento de la inflamacion. | |
| MX383124B (es) | Compuestos tricíclicos fusionados de piridazinona útiles para tratar infecciones de orthomyxovirus. | |
| BR112019007576A2 (pt) | compostos de bifenil sulfonamida para o tratamento de doenças ou transtornos renais | |
| MX2021011507A (es) | Compuestos farmaceuticos para el tratamiento de trastornos mediados por complemento. | |
| BR112016024176A2 (pt) | composições para tratamento bucal tendo estabilidade aprimorada | |
| DOP2016000161A (es) | Ureas asimétricas p- sustituidas y usos médicos de las mismas. | |
| CL2016000677A1 (es) | Compuestos derivados de etinilo, moduladores alostericos positivos del receptor mglur4; composicion farmaceutica que los comprende; y su uso en enfermedades del snc, cancer y diabetes tipo 2. | |
| CO2019002245A2 (es) | Combinación de agonistas de fxr | |
| UY37729A (es) | NUEVOS COMPUESTOS QUE INHIBEN LA ACTIVIDAD DE Nav1.7 | |
| BR112018067554A2 (pt) | formulações de testosterona e métodos de tratamento com as mesmas | |
| MX2018000872A (es) | Combinaciones terapeuticas de paclitaxel oralmente administrado y un inhibidor de la bomba de p-glicoproteina (p-gp) para el tratamiento del cancer. |